November 2015 Newsletter 
Clinical Trial Working Groups
  • Approved LOI:
    • ER+ and/or PR+ and HER2- breast cancer (Illinois)
    • AR+ triple negative breast cancer (Wisconsin)
  • Current concepts:
    • First line triple negative metastatic breast cancer (Penn State)
    • Newly diagnosed ER+, HER2- breast cancer (Minnesota)
    • Triple negative breast cancer (Wisconsin)
  • Next call: TBD; see you at SABCS!
  • Trial in start-up: Hepatocellular (Indiana)
  • Approved LOI:
    • Esophageal (Indiana) - see also thoracic
    • Gastric/GE junction adenocarcinoma (Northwestern)
  • Current concepts
    • Hepatocellular (Wisconsin)
    • Colorectal (Wisconsin) - on hold until Q1 2016
    • Pancreatic (Penn State)
  • Next call: Friday, December 18 at 3 p.m. ET / 2 p.m. CT; see you at GI ASCO!
  • Open trial: Renal cell carcinoma (Illinois)
  • Current concepts:
    • Bladder (Iowa)
    • Bladder (Penn State)
  • Next call: Friday, December 11 at 10 a.m. ET / 9 a.m. CT.; see you at GU ASCO!
  • Trial in start-up: Endometrial carcinoma (Northwestern)
  • Current concept: Ovarian (Rutgers)
  • Next call: TBD
  • Current concepts:
    • Peripheral T-cell lymphoma (Michigan) -
      4 concepts, not yet presented
    • Cutaneous T-cell lymphoma (Michigan) -
      2 concepts, not yet presented
    • Lymphoma (Minnesota)
  • Next call: Wednesday, November 11 at 11 a.m. ET / 10 a.m. CT;
    see you at ASH!
  • Current concepts:
    • Squamous cell carcinoma of the skin (Rutgers)
    • Melanoma brain metastasis (Michigan)
    • Uveal melanoma (Michigan)
  • Next call: Monday, December 14 at 2 p.m. ET / 1 p.m. CT
  • Current concept: Multiple myeloma and lymphoma (Indiana)
  • Next call: TBD; see you at ASH!
  • Next call: TBD; see you at ASH!
  • Next call: TBD
  • Approved LOI:
    • Esophageal (Indiana) - see also gastrointestinal
    • NSCLC (Illinois)
  • Current concepts:
    • Mesothelioma (Illinois)
    • Splice variants in lung cancer in women (Illinois)
    • HER2 expression and targeted therapy (Illinois)
  • Next call: Thursday, November 5 at 1 p.m. ET / 12 p.m. CT
 
To Discuss Protocols: Contact Jessica Roy at [email protected] or 317-634-5842, ext. 19

To Join a CTWG or Submit an LOI: Contact Donna LaPlaca Sullivan at  [email protected] or 317-634-5842, ext. 40.

Support the BTCRC
BTN spotlights consortium
If you enjoy watching live events and programs on the Big Ten Network, watch for a new promotional spot highlighting the BTCRC, now airing on the Network. The making of this 30-second video was a team effort, with support from all member institutions.  Watch on YouTube .


BTN LiveBIG: The Big Ten vs. Breast Cancer

BTN LiveBIG, a program of the Big Ten Network, featured several Big Ten cancer centers in a web-based spotlight on breast cancer during October.

Check out the full story on BTN LiveBIG:
Opportunities for investigators

Meetings for Heme, Breast, GU & GI working groups

The BTCRC will host in-person meetings for the hematologic malignancies, breast, genitourinary, and gastrointestinal clinical trial working groups at national meetings noted below. Click the links for further details and to RSVP.

Call for Abstracts: Pan Pacific Lymphoma Conference

The University of Nebraska Medical Center is now accepting abstracts for the 2016 Pan Pacific Lymphoma Conference. The UNMC-sponsored event, which brings together more than 500 members of the multidisciplinary lymphoma clinical team, will take place July 18-22, 2016, in Koloa, Hawaii. Learn more.

Featured Member Profile
Indiana University Melvin and Bren Simon Cancer Center

"The NCI has established criteria for transdisciplinary collaboration and now recognizes the importance of inter-institution collaboration. These are, typically, seen with one investigator collaborating with another. The uniqueness of the BTCRC is that institutions, not just investigators, are collaborating together for a common cause. The tie with the athletic conference embodies the notion that our institutions may compete against each other on the athletic field, but in this fight against cancer, we are all on the same team." Read more in this conversation with Patrick J. Loehrer, Sr., MD, director of the Indiana University Melvin and Bren Simon Cancer Center, our featured member for November. 

To see past member features, click here.
Q&A: Budgets 
Our BTCRC FAQ series continues with a focus on budgets. Questions addressed in this FAQ include:
  • What is the process for submitting a budget with the LOI to the funder?
  • What is the timeline for budget submission to a funder?
  • How will participating institutions be compensated?
  • Is the budget submitted with the LOI the final budget?
  • How do you determine site start-up and patient care costs?
Across the Consortium
In our latest edition of  Across the Consortium, we recount the innovative breakthroughs of member institutions asking - and answering - big questions. We also glean inspiration from the breakaway performances of Big Ten research leaders achieving new milestones and paving the way for the leaders of tomorrow. As the impact of senior faculty deepens, new training programs broaden the pool of future talent.   Read more .


Tackling lung, pancreatic, and stomach cancers

November is the national month of awareness for pancreas, stomach, and lung cancers. Within the Big Ten Cancer Research Consortium, member institutions are tackling these cancers through innovative multidisciplinary efforts that leverage the scientific expertise of Big Ten universities.