Weekly Nutrition Newsletter
SPMs NOW: Current Therapeutic Research Areas
Interview Series with Dr. Charles Serhan, PhD, DSc

In part 2 of a new SPM series from the 15 th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases, October 2017 in Puerto Vallarta, Mexico, listen in as Dr. Charles Serhan answers the question: “ Can you describe some therapeutic areas where specialized pro-resolving mediators are currently being investigated for clinical use? ” Dr. Serhan discusses the most current, ongoing therapeutic research assessing SPM efficacy, including applications in pulmonary, cardiometabolic, vascular, joint and cognitive health, as well as pain and wound healing

Dr. Charles Serhan, PhD, DSc is Director of the Center for Experimental Therapeutics and Reperfusion Injury at Brigham and Women’s Hospital and Professor of Anesthesia at Harvard Medical School
The Nonnutritive Sweetener Paradox

Nonnutritive sweeteners (NNS) including aspartame, sucralose and stevioside are zero- or low-calorie sugar substitutes that were designed to limit caloric intake and assist in weight and blood glucose management, but recent findings link nonnutritive sweetener use to higher adiposity and cardiometabolic risk

NNS are widely consumed in the US by 25% of children and 41% of adults. A recent study quantified the long-term impact of routine NNS consumption on obesity and cardiometabolic endpoints in over 400,000 patients
Pregnancy Hypertension to Chronic Hypertension: Weight Matters

Hypertensive disorders of pregnancy (HDP) are obstetric complications including pre-eclampsia and gestational hypertension (HTN). In the US, pre-eclampsia and gestational HTN affect 3% and 5-10% of pregnancies, respectively. Researchers from Brigham and Women’s Hospital and Harvard University recently investigated the impact of lifestyle risk factors on the development of chronic HTN in patients with history of HDP. The prospective Nurses’ Health Study II cohort included 54,588 women aged 32-59 years
In this presentation from The New York Academy of Sciences, Frank Hu, MD, PhD, Professor of Nutrition and Epidemiology at Harvard School of Public Health and Harvard Medical School, provides an edifying overview of the relationship between nutrition and metabolic diseases, with a systems epidemiology approach

Dr. Hu explores the genetic impact of common foods or ingredients such as sugar sweetened beverages, caffeine and amino acids on type 2 diabetes. The evidence Dr. Hu presents supports the importance of a healthy diet and lifestyle to attenuate the obesity loci on our genes and ultimately reduce the chronic disease burden
Frank Hu, MD, PhD
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