Health Security Headlines
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Today's Headlines: February 19, 2018

Biological Agents & Infectious Diseases

Influenza Activity--United States, October 1, 2017-February 3, 2018 ( MMWR) Influenza activity in the US began to increase in early November 2017 and rose sharply from December through February 3, 2018; elevated influenza activity is expected to continue for several more weeks. Influenza A viruses have been most commonly identified, with influenza A(H3N2) viruses predominating, but influenza A(H1N1)pdm09 and influenza B viruses were also reported. This report summarizes US influenza activity during October 1, 2017-February 3, 2018, and updates the previous summary. Go to article


Government Affairs & National Security

DSI's Joint Civil and DoD CBRN Symposium to Explore Government-Wide Approaches to Defense, Response, and Recovery ( Homeland Preparedness News) Homeland security stakeholders will gather on March 5-6 in Virginia at the 6th Annual Joint Civil and Department of Defense Chemical, Biological, Radiological and Nuclear Symposium, where participants will have the opportunity to discuss challenges and improvements to the nation's CBRN defense, readiness, response and recovery posture. Go to article

The National Defense Strategy: A Compelling Call for Defense Innovation ( War on the Rocks) At first glance, you might think these quotes were from a CEO who just took over a company facing disruption from agile startups and a changing environment. And you'd be right. But in this case the CEO is the secretary of defense. And his company has 2 million employees. Go to article

Blue Ribbon Study Panel on Biodefense Awarded $2.5 Million Grant ( Homeland Preparedness News) The Open Philanthropy Project awarded a $2.5 million grant to the Blue Ribbon Study Panel on Biodefense on Thursday, which will be used to help the organization continue to assess biodefense, identify needed changes and make recommendations. Go to article


Global Health Security

Monkeypox in Nigeria: The Value of Local Surveillance and Genetic Sequencing ( Global Biodefense) Scientists performed genetic sequencing of patient samples from the monkeypox virus (MXPV) outbreak in Nigeria, revealing that the outbreak likely originated from a source within the country. Go to article

See Also: Genomic Characterisation of Human Monkeypox Virus in Nigeria ( The Lancet) First identified in 1958, MPXV has caused sporadic human outbreaks in central and west Africa, with a mortality rate between 1% and 10%. Viral genomes from west Africa and the Congo Basin separate into 2 clades, the latter being more virulent. Recently, MPXV outbreaks have occurred in Sudan (2005), the Republic of the Congo and Democratic Republic of the Congo (2009), and the Central African Republic (2016). Go to article


Medicine & Public Health

TSRI Scientists Receive $15 Million to Study Viral Outbreak Survivors ( Phys.org) With a new $15 million grant, scientists at The Scripps Research Institute are gearing up for an in-depth study of survivors of viral outbreaks. The grant from the National Institutes of Health's National Institute of Allergy and Infectious Diseases will support the efforts of the TSRI-led Center for Viral Systems Biology to fight Ebola and Lassa viruses.  Go to article

Cryptosporidium: Novartis and the Bill & Melinda Gates Foundation Form Alliance to Develop Drug Candidate ( Outbreak News Today) Novartis and the Bill & Melinda Gates Foundation have formed an alliance to advance development of Novartis' drug candidate KDU731 for the treatment of cryptosporidiosis. Diarrheal diseases are one of the leading causes of childhood mortality globally, resulting in approximately 525,000 deaths each year and cryptosporidiosis is the second leading cause of infectious diarrhea in children under 2 years of age. Go to article

Brazil Battles Yellow Fever--And A 'Dangerous' Anti-Vaccination Campaign ( Washington Post) With cases of yellow fever multiplying in Brazil, Paula Muniz, a 42-year-old accountant, was considering whether to get vaccinated. Then she saw a viral Facebook post about a teenage girl's supposedly fatal reaction after receiving the vaccine, and she decided it was a firm no for her, her 14-year-old son and her husband. Go to article

Apple's Move to Share Health Care Records is a Game-Changer ( Wired) In late January, Apple previewed an iOS feature that would allow consumers to access their electronic health records on their phones. Skeptics said the move was a decade too late given a similar (and failed) effort from Google. Optimists argued that Apple was capable of translating health data into something meaningful for consumers. Go to article


Science & Technology

China Develops a New Intranasal Flu Vaccine ( Healthworld) Scientists in China have developed a new intranasal flu vaccine using nano-technology that can target broad-spectrum flu viruses and induce robust immune responses. Go to article

In the Future We Won't Edit Genomes--We'll Just Print Out New Ones ( MIT Technology Review) At least since thirsty Sumerians began brewing beer thousands of years ago, Homo sapiens has had a tight relationship with Saccharomyces cerevisiae, the unicellular fungus better known as brewer's yeast. Through fermentation, humans were able to harness a microscopic species for our own ends. These days yeast cells produce ethanol and insulin and are the workhorse of science labs. Go to article

Horsepox Synthesis: A Case of the Unilateralist's Curse? ( Bulletin of the Atomic Scientists) Horsepox is a virus brought back from extinction by biotechnology. In 2016, the Canadian researcher Ryan Noyce, along with colleagues, synthesized a copy of horsepox DNA from the virus's published DNA sequence, placed it into a cell culture alongside another poxvirus, and in this way recovered copies of "live" horsepox virus. Go to article

New CRISPR Tools Can Detect Infections Like HPV, Dengue, and Zika ( The Verge) Scientists are harnessing the same technology behind the powerful gene-editing tool CRISPR to develop cheap devices that can quickly diagnose infections. These systems, described in new research, have the potential to revolutionize how we detect and respond to viruses like HPV and Zika, especially in developing countries. Go to article


Other 21st Century Threats

Public Reports 'Clearly Show' Assad's Use of Chemical Weapons: McMaster ( Reuters) US National Security Adviser HR McMaster said on Saturday that, despite denials, public reports showed that Syrian President Bashar al-Assad was using chemical weapons, and added that it was time for the international community to hold the Syrian government to account.  Go to article


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