INVO NEWSLETTER 
Summer 2016 
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National Recognition of Northwestern Faculty  

Prof. Teri Odom (Weinberg)
was recognized for her outstanding achievements and contributions to science by being named a
2016 American Chemical Society Fellow .  Prof. Odom's research lab focuses on "controlling materials at the 100-nanometer scale and investigating their size and shape-dependent properties.  [They] have developed massively parallel, multi-scale nanopatterning tools to generate noble metal structures that can manipulate visible light at the nanoscale, including  a
for fabricating materials for nanophotonic and sensing applications 
 
Prof. Tobin Marks (Weinberg)
was recognized by the American Chemical Society with the 2017 Priestley Medal for his pioneering work in "catalytic polymerization, organometallic chemistry, organic opto-electronic materials and electronically functional metal oxides."  Some of his technologies include organic photovoltaics , catalysts for polymerization , and an electro-optic modulator. This award is the highest honor bestowed by the world's largest scientific society. 
 

Prof. Jian Cao (McCormick)
was recognized by the Society of Manufacturing Engineers with the 2016 SME International Honor Award .  Prof. Cao's research focuses on innovative manufacturing processes and systems, including laser-induced plasma micromachining and a desktop micro surface texturing system. 
 

Prof. Samuel Stupp (McCormick and Weinberg)
was honored with the Royal Society of Chemistry's Soft Matter and Biophysical Chemistry Award.  He was recognized for his contributions to the science of supramolecular soft matter and for demonstrating its value to control biophysical interactions with mammalian cells.  For example, he discovered self-assembling peptide ampliphiles that form nanofibers for tissue scaffolding or other peptide ampliphiles that promote neurite growth.

 
was invited to speak at the prestigious Milken Institute's Global Conference in May 2016. Prof. Backman's research focus is the "development of novel optical spectral and imaging techniques for non-invasive screening, diagnosis and detection of disease."   Two examples of his inventions are inverse scattering optical coherence tomography and an improved structured illumination microscope for generating higher resolution medical images.  Prof. Backman has two startups, American BioOptics and Nanocytomics, that are developing technologies that help to better diagnose and detect cancer.

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NU Innovation Recognition in the Media   



Feinberg Prof. Stephen Miller and former McCormick Prof. Lonnie Shea received media attention by Scientific American after a recent publication in the
Proceedings of the National Academy of Sciences.  The collaborating scientists are developing a new way to treat allergies using nanoparticles that cloak allergens and help teach the immune system not to attach safe allergens. 


Feinberg Prof. Dane Chetkovich, published a paper in Molecular Psychiatry showing his work that gene therapy targeting the hippocampus may be an additional anti-depression therapy.  The work was covered in The Science Explorer .  

 

McCormick Prof. Michael Jewett was cited by
Nanowerk for his significant work in synthetic biology. 

 
Feinberg Prof. Teresa Woodruff and McCormick Prof. Ramille Shah have collaboratively worked to develop a way to 3D-print mouse ovaries.  When implanted into mice, whose ovaries were removed, they allow the mice to ovulate, give birth and nurse.  Watch "Form Following Fertility: Innovations in Complex Tissue Engineering" by Monica Laronda in her TEDx Talk.  Coverage by Chicago Tribune. 
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New INVO Agreements
 
INVO executed
15 
licensing & option agreements 
since
January 1, 2016    
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Upcoming Events 

Wildfire Demo Day at The Garage (Aug 25).  The Garage offered a 10-week accelerator program, providing student startups access to workspace, mentorship, entrepreneurship curriculum and a $10,000 stipend.  Teams will present at Demo Day .  Time:  5:30.  Location:  Evanston

INVO Seminar (Oct 5):
Commercialization of Research Tools.  Our guest speaker from Millipore will be sharing an industry perspective on their considerations as they select and develop platforms to bring to the market.  Time 4pm. Registration information will be available here.  Location: 
Evanston

The Garage Seminar (Nov 9):  Startups 2.0.
  Osage Partners will give a primer on startups addressing company formation, funding, creating an elevator pitch and pitch deck and how VCs assess opportunities and develop investment memos.  Registration information will be available here.  Time: 5pm. Location: 
Evanston

INVO Seminar (Nov 10):  Venture Capital.  Osage Partners will lead an in-depth
look at the workings of VC investment decisions including who/how/when to approach VCs, making the pitch, investor due diligence, term sheets, and syndication .  The talk is geared towards faculty, staff, post-docs or students.  Registration information will be available here.  Times: TBD.  Locations:  Evanston and Chicago 
 
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About Us

The Innovation and New Ventures Office inspires and nurtures a culture of innovation, bridging Northwestern research with its practical use for public benefit.

INVO

1800 Sherman Ave, Suite 504
Northwestern University
Evanston, Illinois 60201
847.467.2097
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Faculty Startup Milestones
Weinberg Prof. Chad Mirkin's public company, Nanosphere was acquired b y Luminex for $58M at $1.35/share.
Click here for the Press Release. Nanosphe re has developed the Verigene Sys tem, a point-o f-care molecular diagnost ic tool that enables clinicians to deliver timely and targeted therapy for critical life-threatening infectious diseases.  

Transplant Genomics, co-founded by Feinberg faculty physician, Michael Abecassis, entered an Immunosuppressive Clinical Trials collaboration with Astellas Pharmaceuticals. Click
here for the Press Release.  Transplant Genomics is a molecular diagnostics company that intends to improve organ transplant management and outcomes through tests that detect early signs of graft injury, differentiate among actionable causes and enable optimization of therapy.
 
TRACT Therapeutics received FDA approval for Phase 2 trials using patients' immune cells.  Click
here for coverage on this milestone.  TRACT is a biotech company developing personalized regulatory T-cell therapies to help restore immune balance to transplant recipients so their bodies will accept the foreign organ instead of rejecting it.  
 

Bold Diagnostics successfully completed their participation in CIMIT, the Center for Integration of Medicine and Innovative Technology, in Boston.  More information.

Student startup working out of The Garage, 89 Robotics, made Inc's top 10 college startup list.  More information. 
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NU Startup Fundraising

Aptinyx, McC Prof. Joseph Moskal's second startup, received $65M for clinical trials focused on managing nerve-related pain.  This milestone received coverage by Chicago Tribune and Modern Healthcare.  

SiNode Systems, a Northwestern startup commercializing technologies by McCormick Professors Harold Kung and Jiaxing Huang, won a $4M award from US Advanced Battery Consortium to create electric cars.  Half of the award is funded by the US Department of Energy.  Click here for the Crain's article covering this milestone.

Hazel Technologies won the $500k Clean Energy Trust Award.  Hazel has created two primary products:  (1) FruitBrite™ is a carton insert that extends the shelf life of ethylene sensitive produce; and (2) Berrybrite™ is a berry clamshell insert that uses a blend of essential oils to increase the shelf life of berries by up to 3x in cold storage.  The Chicago Tribune covered this achievement.

Luna Lights recently raised $225k from various investors .  Luna Lights is an automatic lighting solution that prevents night time falls, by automatically turning on mountable lights when a user gets out of bed.  The system illuminates potential trip hazards and creates a lighted, guided path through a dark home.  

The Northwestern Center for Device Development (CD2) team that created Bold Diagnostics was awarded the National Science Foundation's SBIR Award for $225k to further develop their new cuffless blood pressure monitoring technology--an impressive award considering they have only been together for less than one year.  Congratulations to the rock star CD2 team: Kyle Miller MD, Jay Pandit MD, Sean Connell PhD and Andrew Wu MS.

Preora Diagnostics won 2nd place at the 2016 PROPEL competition.

MDAR won 4th place at the University of Oregon's New Venture Championship.


Surginet won 1st place ($20k) at the Northwestern University Venture Challenge.

Nort hwestern startups performed well at the Rice Business Plan C  ompetition.  Overall finishes included Hazel Technologies (3rd place), Bold Diagnostics (4th place), and MDAR (6th place).  Hyperlinks for respective elevator pitches are:   Hazel Technologies , Bold Diagnostics , and MDAR .  In addition, Bold Diagnostics won over $125k in prizes. 
 
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INVO Welcomes Two New Colleagues:
Vara Prasad Josyula & Lisa Dhar     
Vara Prasad Josyula, PhD
Invention Manager 
Vara brings over twenty years of pharmaceutical research and development experience to INVO, working with both large multi-national pharmaceutical and small bio-tech companies.  He started as a senior chemist with Parke-Davis and moved up the ranks to Research Fellow with Pfizer.  Later, he worked as a Senior Director with PTC Therapeutics.  He is an author/co-author of over 75 publications in peer-reviewed journals and inventor/co-inventor of over 35 patents/patent applications.  Vara Prasad earned his M.S. in Chemistry from Indian Institute of Technology, Roorkee and Ph.D. in Chemistry from Indian Institute of Technology, Chennai. He is certified to practice before the United States Patent and Trademarks Office.   Vara joined the INVO team in March 2016 and primarily manages technology portfolios in medicinal chemistry, life sciences and biomedical engineering.

 
Lisa Dhar, PhD
Director of New Business Ventures for Engineering at INVO and McCormick School of Engineering and Applied Science 
Lisa is a faculty member of the Farley Center for Entrepreneurship and Innovation.  Lisa was co-founder and vice president of InPhase Technologies, a company spun out of Lucent Technologies and was most recently the Senior Associate Director of the Office of Technology Management at the University of Illinois at Urbana-Champaign. Lisa has served on the National Academies' Assessment Panel on Materials Science and Engineering at the National Institute of Standards and Technology (NIST) and on the Advisory Board for University of Colorado's Women in Engineering Program.  Lisa holds a Ph.D. in Physical Chemistry from the Massachusetts Institute of Technology and a B.S. in Chemistry from the University of Chicago.
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Other INVO News... 
 
$10M N.XT and $4M NUseeds FUNDS ANNOUNCED
This spring, Northwestern announced the launch of two funds to support the commercialization of technologies by faculty and students.  The N.XT Fund is geared towards technologies that are patented by Northwestern and typically are discoveries based on faculty research.  The NUseeds Fund, managed by The Garage, offers seed investment for student startups.  Chicago Tribune article.
 
INTERNSHIP PROGRAM:  INVO PRACTICUM 
The INVO Practicum welcomed its 4th cohort of interns in July.  They include:  (left to right) Laura Whittenburg (MS, BME, McC), Rachel Lander PhD (Post-Doc, Molecular Biosciences, Weinberg), Jose Martinez (PhD, Chemistry, Weinberg), and Natalie Greco PhD (Post-Doc, Cell & Molecular Biology, Feinberg).  INVO is fortunate to have two senior interns (not pictur ed) stay beyond their 6-month program: Hilary Chase (PhD, Chemistry, Weinberg) and Yunli Ma MS (McCormick) . After intense training, INVO interns gain hands-on experience with performing patentability assessments and market analyses and marketing technologies.  Some of our interns have moved onto a variety of positions including tech transfer offices at the Ludwig Institute for Cancer Research, Rice University, and MIT.  Others have taken positions as technical specialists in industry and law firms.  One intern moved onto a tenure track professorship at another university. INVO is extremely proud of their accomplishments.  Applications for the January 2017 cohort are available online at this link.
 
CD2 FELLOWS PROGRAM
 
The CD2 Innovation Fellowship has come to a close.  The final class of innovation fellows, ( Andrew Wu, MS, Kyle Miller, MD, MBA, Jay Pandit MD, and Sean Connell PhD) completed their business plan competition circuit with a 4th place finish at the Rice Business Plan Competition along with over $128,000 in prizes.   BOLD Diagnostics received many recognitions, including: $5,000 Rice Business Plan Competition Fourth Place Award sponsored by Ernst and Young; $25,000 Cisco Internet of Everything Innovation Challenge Prize;  $25,000 TMCx Digital Health Accelerator Prize; $20,00 0 NASA Earth/Space Human Health and Performance Innovation Cash Award;  $50,000 TiE RBPC Angel Investment Prize;  $3,000 Best Written Business Plan sponsored by Palo Alto Software; Mercury Fund Elevator Pitch Competition 4 th Place Prize;  2016 Rice Business Plan Competition Semi-Final Round Flight 2 1 st Place Award. INVO is grateful for the generous funds donated by devoted Northwestern philanthropists who have allowed us to explore medical innovation and commercialization through McCormick and Feinberg over the last three years.   


I2C SUMMER FELLOWSHIP GRADUATES ITS 3RD COHORT  
The I2C Summer Fellows completed their INVO program with  final presentations on August 5.  The six fellows pictured below (left to right) are:
Smit Naik (MBA, Kellogg), Hongbin Zhu (JD/MBA, Pritzker/Kellogg), Amir Vahabikashi (PhD, McCormick), Seoan Huh (PhD, Feinberg), Stephanie Niemczyk, (PhD, Feinberg) and Yali Li (LLM, Pritzker).  The mission of the I2C program is to help commercialize Northwestern intellectual property assets by allowing our graduate students take a deep dive into addressing the needs of our technologies or startups.  This summer, they made significant progress on twelve projects in the following areas: medical devices, diagnostics, software, nanotechnology, therapeutics, and research tools.  One I2C fellow from Kellogg, Smit Naik, said, "As an MBA candidate, I've found that my time working alongside Northwestern inventors as well as other passionate, intelligent fellows has been absolutely pivotal in shaping the way I understand the intersection of science and business.  The I2C Fellowship has catalyzed my growth in an amazingly meaningful way."  Alicia L öffler Associate Provost for Innovation and New Ventures stated, "The work that the fellows achieved was outstanding and will help inform INVO of the commercialization strategies for these innovations.  At the same time, the fellows gained important practical business experience that will open the doors to a variety of career opportunities."   
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INVO & Social Media 

TWITTER
Follow us on Twitter ( @INVOatNU ) where we tweet news related 
to INVO, Northwestern technologies and startups, and local entrepreneurial activities.

LINKEDIN
Connect with INVO through our group on LinkedIn. INVO will utilize this new group to highlight news on Northwestern technologies that are either available for licensing or being commercialized by a startup.
 
YOUTUBE
Check out our new Innovation and New Ventures @Northwestern channel on YouTube for direct access to our videos.