January 2018
News
Happy New Year!
We made it through 2017 with some challenges and many opportunities. In fact, we thrived because of your incredible hard work and dedication. I am personally grateful to each one of you for your tremendous efforts and accomplishments.

As we enter 2018, we will build upon our successes and continue to pursue initiatives that will increase our collaborative opportunities. As Principal Investigator of the Clinical and Translational Science Collaborative, I am committed to providing a rich environment for training and education and the resources designed to develop, support, and promote clinical and translational research and innovation.

The CTSC has made it possible to develop research relationships and collaborations between investigators within our partner institutions, as well as nationally and internationally, to accelerate research. The CTSC has also made it possible to collaborate with other organizations to advance our clinical and translational research initiatives. We are proud to have built and nurture an environment to efficiently accelerate discoveries and to train the next generation of clinical and translational researchers.

On behalf of the CTSC leadership team, we want to personally thank the entire CTSC community for contributing to the development, support, and success of our program. We look forward to 2018 and the opportunities that lie ahead for all of us to achieve even greater success!

Best wishes,
Mike
FUNDING OPPORTUNITY: Taipei Medical University-CTSC Collaborative Pilot Program
Pre-proposal Deadline: January 26, 2018
Taipei Medical University along with the Clinical and Translational Science Collaborative (CTSC) is pleased to offer a collaborative pilot award opportunity to promote translational research projects through team science. The objective is to accelerate laboratory discoveries into new treatments and to foster the education of highly skilled scientists and engineers to encourage the next generation of global scientific and engineering leaders. 

The target areas for funding are Oncology, and Neurosciences including traumatic brain injury, stroke and dementia, and all include devices, drugs, diagnostics and software.

Funding for these Pilot Awards will be granted by both TMU and the CTSC. Grants will be awarded in the funding cycle as established by TMU and the CTSC.  TMU and CTSC Pilot Awards will fund up to $50,000, and may be requested for up to 1 year of support. TMU collaborators will be eligible to apply for an additional $25,000 for their part of the project, for a total of up to $75,000.

The deadline for submitting the pre-proposal is 11:59pm on  January 26, 2018 .

Investigators will be invited to submit full proposals by March 1, 2018 with a deadline for full proposals to be April 15, 2018.
 
The full RFA can be found  here.
The template for Pre-Proposals can be found  here.

Contact Anne DeChant with any questions: 216-368-8867 or akd6@case.edu.
The Making of a Citizen-Scientist through Community-Based Research Consultation Service
A community-based research (CBR) evaluation model of consultation services is helping to translate clinical practice observations into research-supported treatment approaches.

For many clinicians, it can be difficult to gather the research data needed to determine how effective a treatment will be for a patient. Ensuring that observations from clinical practice can lead to better therapies is a translational science priority that NCATS seeks to support through its Clinical and Translational Science Awards (CTSA) Program.

Licensed massage therapist (LMT) Diane Mastnardo has demonstrated how challenging this effort in translation can be. She was certain that massage therapy helped her clients by relieving pain, increasing joint flexibility, improving balance and posture and speeding recovery from injuries. Yet medical providers — citing a lack of scientific evidence demonstrating health benefits of massage — often were reluctant to refer their patients to LMTs for therapy. Mastnardo had hit a translational barrier: She needed data about massage therapy, but she couldn’t collect the information without research training or access to resources to carry out a study that could generate the data.

Upcoming Network Events
Research without sites? by Ray Dorsey, MD
January 11, 2018 at 12:00pm ET
Research can increasingly be conducted remotely by bringing research opportunities to patients. We will discuss the future of clinical research highlighting how smartphones and virtual research visits can increasingly enable anyone anywhere to participate in research.

Open Forum: Standard Agreements
January 18, 2018 at 2:00pm ET
Learn more about Trial Innovation Network Website and have an opportunity to ask questions and receive information.

Novel approaches to clinical trials recruitment: Lessons learned from the 2017 Buffalo Creative Scientist Workshop, by Larry Hawk, Ph.D.
January 23, 2018 at 12:00pm ET
Research can increasingly be conducted remotely by bringing research opportunities to patients. We will discuss the future of clinical research highlighting how smartphones and virtual research visits can increasingly enable anyone anywhere to participate in research.

Wish to talk to our local TIN Hub Liaison Team? Complete this  INTAKE FORM  to be connected with our local TIN Hub Liaison Team who can provide advice and input on your proposal and directly connect you to the national network.
Enhanced Secure Environment for REDCap at CWRU
At the request of CWRU Researchers, UTech is providing an enhanced secure environment for REDCap at CWRU.

CWRU-based REDCap users and existing CWRU REDCap projects will be relocated to the Secure Research Environment (SRE) beginning late January 2018. Existing user access/experience will not change--you will use your current URL ( https://redcap.case.edu/redcap/ ). There will be a brief scheduled interruption in the service during the changeover (during non-business hours).

Future communications will address this move’s impact on your projects that may contain Protected Health Information (PHI) from HIPAA covered entities, Personally Identified Information (PII), or new users or projects migrating from partnering hospital systems (with PHI or PII present). In these cases, enhanced security options will be available and UTech/REDCap staff will be available to assist you.

At this time, there will be no change in access or service. If you have questions, please contact the [U]Tech Service Desk at  help@case.edu  or (216) 368-HELP. Refer to the REDCap change. (If you are not using the CWRU REDCap, this relocation will not apply to you, unless you seek to move your REDCap data from its current location to the CWRU instance).
CWRU IRB Implements New Continuing Review Policy for Less then Minimum Risk Studies
Beginning January 1, 2018, the Case Western Reserve University Institutional Review Board (CWRU IRB) will extend the continuing review cycles for non-federally funded studies that are less than minimal risk to three (3) years. Examples of research activities that may be eligible for three (3) year approvals include:
  • Chart reviews
  • Focus groups
  • Interviews
  • Surveys
  • Tissue studies

This change will decrease the administrative burden on researchers.

Please contact the CWRU IRB Office at  (216) 368-6925  or  cwru-irb@case.edu  with any questions about this change.
New Health Informatics Graduate Certificate Program
The Department of Population and Quantitative Health Sciences introduces its newly approved Graduate Certificate Program in Health Informatics. As part of the program, a new course is being offered, " Computing in Biomedical and Health Informatics" , that starts January 19, 2018 (Fridays 2:30-5:30).

Contact Mendel Singer, PhD, MPH with question s: mes12@case.edu or 216-368-1951

Health Informatics News from the
Institute for Computational Biology
Institute for Computational Biology (ICB) Newsletter
The ICB released issue 0.1 (a preview) of its monthly newsletter just before the holiday break, and selected content from that issue is below. If you would like to sign-up for the monthly ICB newsletter, please click on the following link:

EMERSE (Electronic Medical Record Search Engine) – ICB PI: Jill Barnholtz-Sloan, Ph.D.
EMERSE (Electronic Medical Record Search Engine) is a search engine that facilitates the use of free text documents (i.e. clinical, radiology, and pathology notes) in medical records. Developed at the University of Michigan, it supports clinical and translational research, internal quality improvement and quality assurance initiatives, hospital operational support, complex case review, improved reimbursement rates, compliance, risk management and infection control. Importantly, the product is open source. Finally, since 2008, EMERSE has been integral in cohort identification for over 460 clinical trials at the University of Michigan and has been included in over 920 IRB-approved studies.

We are excited to report that, over the next 5 years, the ICB will participate in a consortium grant (U24, Jill Barnholtz-Sloan, Local-PI) that will install, enhance, and expand the utilization of the EMERSE software.  The consortium includes: Case Western Reserve University, University of Michigan, University of Cincinnati, University of North Carolina, Columbia University, and the University of Kentucky. More information about the EMERSE tool can be found here:  http://project-emerse.org/
ICB External Advisory Board Meeting – Held December 11, 2017
The ICB External Advisory Board (EAB) held a site visit on Monday, December 11, 2017 where ICB progress to date and the draft proposal strategic plan for the next five years was presented and discussed. The current ICB EAB members and their respective areas of expertise are:
  • Marylyn D. Ritchie, Ph.D. Geisinger Health System/University of Pennsylvania, Director, Biomedical & Translational Informatics, Computational approaches to analyze Electronic Health Record data
  • Bradley A. Malin, Ph.D. Vanderbilt University, Vice-Chair for Research, Dep’t of Biomedical Informatics, Data security and privacy
  • Warren A. Kibbe, Ph.D. Duke University, Chief Data Officer, Duke Cancer Institute, Professor, Dep’t Biostatistics & Bioinformatics, Biomedical informatics and data sharing
  • Sean D. Mooney, Ph.D. University of Washington, Chief Research Information Officer (UW Medicine), Dep’t Biomedical Informatics, Clinical informatics platforms
  • Kyle B. Brothers, M.D., Ph.D. University of Louisville, Institute for Bioethics & Dep’t of Pediatrics, Ethical, Legal, Social Issues
News from the PRCHN
PRCHN Monthly Seminar Series
Mark your calendars for these upcoming PRCHN seminars:

January 10, 2018
Patterns of Use and Beliefs among Adolescents and Young Adults Who Smoke Cigarillos 
Sue Flocke, PhD; David Cavallo, PhD, MPH, RDN; Elizabeth Antognoli, PhD; Rock Lim, BS; and Sarah Koopman-Gonzalez, PhD

February 14, 2018
Ideas Moving Parents & Adolescents to Change Together (IMPACT) Study Findings
Elaine Borawski, PhD, Director, PRCHN and Angela Bowen Wiliamson Professor of Community Nutrition, CWRU School of Medicine, and IMPACT Team

Mark your calendars for the 2nd Wednesday of each month from 12:00-1:15 pm
 

Latest YRBS Infographic Incorporates Local Youth Tobacco Use Data
The Youth Risk Behavior Survey (YRBS) has been administered in secondary schools throughout Cuyahoga County with support from a variety of funders and community sponsors since 1995. The YRBS is a cross-sectional tool developed by the Centers for Disease Control and Prevention (CDC) to track adolescent risk behavior over time.

This information is important to collect at the national level, and it is beneficial to collect this data on the local level in order to compare the risk behaviors of local teens with those of teens in other communities in Ohio as well as with those behaviors in other urban communities across the country.

News from the Urban Health Intiative
Happy New Year!

Our efforts this past month have focused on establishing or formalizing some partnerships that we anticipate will bring a new host of new data and users to Health Data Matters. Stay tuned as we finalize these details. We've also been busy with proposal writing and planning for two upcoming events:

Location: Cleveland Ohio Global Center for Health Innovation & Cleveland Public Library
We're excited and proud that Cleveland will be hosting the Third Annual Meeting of the National Digital Inclusion Alliance, the only organization dedicated to ensuring that all Americans have the access and skills needed to participate in the 21 st century economy. The summit will feature a pre-conference workshop focused on digital health literacy (April 17 th). This session will provide an opportunity for the small number of us working in this field to meet, share information about activities underway or planned, to consider common measures and strategies for successful partnerships. The conference schedule and registration are available now.

The dates for the 2018 Data Days CLE have not been finalized, but we know there will be plenty of opportunities for attendees to learn about and even create maps and stories with Health Data Matters.

We've also been learning from other communities with endeavors similar to what we're trying to do with Health Data Matters. A couple of examples we've newly investigated include:

  • Rhode Island DataHub features a data catalogue, data stories and data reports that give us some great ideas about organization and navigation.
  • Houston Community Data Connections. This project, with neighborhood indicators, community profiles, and mapping, has been especially important for efforts to assess the impact of flooding from Hurricane Harvey and to consider resource distribution. We especially like their online tutorial and documentation methods.

Take a look and let us know what you think!

Amy R. Sheon, Ph.D., M.P.H.
Executive Director, Urban Health Initiative
Case Western Reserve University School of Medicine
216-368-0915
@CLEhealthCUY
News from our Colleagues
Tools and resources are provided to assist institutions in joining SMART IRB and to help IRB and HRPP representatives and study teams develop processes and procedures for using SMART IRB for their studies.
NIH Extramural Nexus
"Pending in FY 2018 appropriations are significant funding increases for the National Institutes of Health, the Clinical and Translational Science Awards (CTSA) program..."
As the 115th Congress wraps up its first session, Republican legislators continue to work to finalize a comprehensive package of tax cuts. While numerous competing priorities have emerged and details are still being hashed out, the final proposal looks to be a mixed bag for healthcare.

Call for Volunteers
The Clinical Research Forum is looking for volunteers to serve on committees. Our committees include: the IT Roundtable, Finance, Industry Roundtable, Communications, Nominating, and Membership. Please contact admin@clinicalresearchforum.org if you are willing to serve. 
Notice of Changes to NIH Policy for Issuing Certificates of Confidentiality
NOT-OD-17-109 : Effective Oct 1, 2017, NIH will automatically issue Certificates of Confidentiality to all research funded by NIH that is collecting or using identifiable, sensitive information. These new disclosure rules apply to everyone. These Certificates protect the privacy of subjects by limiting the disclosure of identifiable, sensitive information. Effective October 1, 2017, all research that was commenced or ongoing on or after December 13, 2016 and is within the scope of this policy is deemed to be issued a certificate through this policy and is therefore required to protect the privacy of individuals who are subjects of such research in accordance with subsection 301(d) of the Public Health Service Act. Notably, in accordance with  NIH Grants Policy Statement Chapter 15.2.1 , grant recipients are responsible for ensuring that any sub recipient that receives funds to carry out part of the NIH award involving a copy of identifiable, sensitive information protected by a certificate issued by this policy understand they are also subject to subsection 301(d) of the Public Health Service Act. With respect to the CTSA Program hubs this includes KL2 scholar projects and pilot projects. For more information see  Certificates of Confidentiality for NIH Funded Research .
Research Highlights
KL2 Scholar Grad Receives NIH Funding to Expand Countermeasures Against Chemical Threats
Kurt Lu, MD, former CTSC KL2 scholar and assistant professor of dermatology at Case Western Reserve University School of Medicine, has received a five-year, $3.9 million grant from the National Institutes of Health to expand countermeasures against chemical threats, including mustard gas and mustard-related compounds. The molecular action of mustard on DNA leads to strand breaks and eventual cell death. The goal of the grant is to augment the body’s immune system after exposure, reducing skin swelling and pain as well as enhancing tissue repair.

Research Management: Connecting the Dots of the Process of Conflict of Interest Management and Institutional Review Board Management
Philip A. Cola, PhD, Adjunct Assistant Professor of Medicine at CWRU, and colleague, Adrienne Dumke, MBA, Research Integrity Specialist at the University of Louisvill e find that a breakdown or interruption of information flow between the IRB and COI offices or committees adds to the complexity and challenges of maintaining the delicate balance of ensuring compliance while limiting investigator burden in carrying out their research.

Noteworthy Research
Events
2nd An nual Cancer Disparities Symposium:
"Taking it to the Streets: Where Cancer Disparities Research and Community Intersect"
March 23, 2018
Wolstein Research Building - CWRU Campus
This event will showcase cutting-edge research, with a focus on reducing and eliminating disparities in cancer, going from bench-to-bedside-to-community and back. This important symposium will also feature two keynote addresses, including a key leader in our community, and an internationally-recognized cancer disparities researcher. This event will promote the exchange of ideas and collaborative opportunities among scientists, clinicians, government, and community representatives.
 
The Case Comprehensive Cancer Center and Office of Cancer Disparities Research invites abstracts from attendees, organized into two areas:  Academic Science  and  Community Abstracts must be submitted via email to  caseccc-OCDR@case.edu  by 5 pm on January 5, 2018. 
National Digitial Inclusion Alliance:
Net Inclusion 2018
April 17-19, 2018
Global Center for Health Innovation & Cleveland Public Library, Cleveland, OH
Thanks to the robust engagement of local advocates, the third annual Net Inclusion Summit will be held in Cleveland. Academics, advocates, policymakers and community members will discuss policy innovations to improve digital equity, and the science around the impact of digital skills and connectivity on many aspects of life. A number of us are planning a pre-conference workshop focused on addressing disparities in use of digital tools for improving health. If you are interested, please contact Amy Sheon.
Injury Control Research Center for Suicide Prevention (ICRC-S)
May 7-11, 2018
University of Rochester, New York
The Injury Control Research Center for Suicide Prevention (ICRC-S)  has announced that its fourth Research Training Institute (RTI) will take place on Monday, May 7th to Friday, May 11th, 2018 at the University of Rochester in Rochester, NY.

The RTI is a five-day series of interactive workshops, presentations, mentoring and small group sessions designed to promote collaboration between suicide prevention researchers and those involved in suicide prevention practice. Faculty include staff from the University of Rochester Medical Center and other experts in the suicide prevention research field. Applicants will be selected through a competitive process that requires researchers and injury prevention/suicide prevention professionals to work as partners to submit one joint application describing a research project which focuses on public health approaches to suicide prevention. 

Application Deadline: January 12, 2018

For more information visit the  ICRC-S website .
2018 Science of Team Science (SciTS) Conference
May 21-24, 2018
University of Texas Medical Branch, Galveston, TX
Workshop Submission Deadlin e: February 5, 2018
Abstract Submission Deadline: March 20, 2018
 
The  SciTS conference  is the annual international forum dedicated to SciTS, bringing together thought leaders from a broad range of disciplines and fields, including: communications, management, social and behavioral sciences, information technology, systems science, and translational research. It provides investigators, academic administrators, and funders with state-of-the-art knowledge, strategies, and connections. SciTS scholars, scientists engaged in team-based research, institutional leaders who promote collaborative research, policymakers, and federal agency representatives will be in attendance. 
 
This year’s conference for the SciTS community will be hosted by the University of Texas Medical Branch in Galveston, Texas on May 21-24, 2018.
 
Workshops
The SciTS Program Committee invites submissions from individuals or groups to conduct  Special Interest Workshops and Seminars .
 
Workshops/Sessions will be 3.5 hours or 6.5 hours in length. All topics relevant to the application of Science of Team Science approaches are welcomed, specifically with respect to training sessions that will equip SciTS investigators with tools and technical skills for data collection, analysis, or presentation in their research areas. Workshop/seminar proposals that incorporate a variety of instructional approaches (e.g. lecture, interactive discussion, hands-on exercises) and materials (e.g. slides, handouts, sample data) are strongly encouraged. We encourage workshops or seminars with a focus on methodologies including systems approaches to the field of SciTS as well as methodologies for conducting evaluation and understanding team dynamics. Furthermore, we welcome workshops and seminars that provide practical guidance for conducting and managing team science in a variety of contexts and settings, and workshops with a focus on developing team science educational and training resources.
 
All workshop submissions should include the information listed in the attached Call for Workshops and should be submitted through our  Workshop Submission Form Acceptance notifications will be made in March 2018, and Workshops will be held between May 21 and 24, 2018.
 
Abstracts
The SciTS Program Committee also welcomes  abstracts  for paper presentations, lightning round presentations, and panel presentations, as well as scientific posters.
 
Paper, Lightning Round, and Poster abstracts are limited to one page, while Panel abstracts are limited to four pages. Abstracts not meeting these page limits will not be considered. A panel proposal must include an abstract summarizing the overall theme of the panel, and panel submissions showcasing research papers should also include individual abstracts for each individual presentation.
 
All abstract submissions should utilize the attached  Abstract Template  and should be submitted through the Abstract Submission Form Acceptance notifications will be made in April 2018. Presenting authors will be responsible for conference registration, travel, and hotel costs. Poster presenters will be responsible for poster printing costs. Abstracts will be compiled and made available to participants.
 
More information about submitting a Workshop proposal or Abstract is attached, and information about conference registration, fees, and additional travel and lodging details will soon be posted on  the conference website .
 
Questions? Contact the conference planning team at  SciTS.2018@utmb.edu.
Funding Opportunities
New HHS, NIH Grant Programs
Following in their long traditions of helping to support important scientific research, the National Institutes of Health and the Department of Health and Human Services have released information on new grant and award programs that we encourage members to take advantage of.

To read more about these award opportunities, check out the  NIH's "Find Funding" website.
I-Corps@Ohio - 2018
Application Deadline: January 16, 2018
I-Corps@Ohio  is a statewide program developed to assist faculty, staff and students from Ohio universities, colleges and community colleges in validating the market potential of technologies and launching startup companies. I-Corps@Ohio is modeled after the National Science Foundation’s (NSF) successful I-Corps (Innovation Corps) program, which has been proven to increase innovation, entrepreneurship, and industry collaboration. The I-Corps@Ohio program incorporates lean launch, customer discovery and business model innovation methodologies to assess technologies and enhance the business acumen and networks of research faculty and students.

The long-term objective is to drive sustainable technology-based, entrepreneurial economic growth in Ohio. I-Corps@Ohio is offered on a competitive basis to teams comprised of research faculty or staff members, student(s) and executive mentor(s). Teams develop market-driven value propositions and scalable business models that attract seed, angel and venture funding to support company formation, market entry, and accelerate the growth of income and jobs in Ohio.

The primary goals of the I-Corps@Ohio program are to advance the translation of fundamental research to innovative products and services that drive scalable business models that serve as the basis for startup companies. Furthermore, the program recognizes that these new ventures must be of sufficient merit to attract subsequent third-party funding, to encourage collaboration between academia and industry, and to train students and faculty in the practice of innovation and entrepreneurship. Teams that receive I-Corps@Ohio funding are required to complete an intensive 8-week, hands-on training program. The curriculum is designed to help aspiring entrepreneurial teams understand the market for their technology, develop a compelling commercialization strategy and attain new skills that will be very useful to a long-term career in research and development.

For more information, visit the   I-Corps@Ohio webpage .
Burroughs Wellcome Fund
Application Deadline: January 16, 2018
The Burroughs Wellcome Fund  is accepting applications for its 2018 Postdoctoral Enrichment Program.

The annual program awards grants of up to $60,000 over three years to support career-development activities for underrepresented minority postdoctoral fellows in a degree-granting institution (including affiliated graduate and medical schools, hospitals, and research institutions) in the United States or Canada whose training and professional development are guided by mentors committed to helping the fellow advance into a career in biomedical or medical research.

Up to twelve grants will be awarded for enrichment activities annually. Grants are meant to supplement the training of postdocs whose research activities are already supported by other sources.

To be eligible, applicants must have no more than thirty-six months of postdoctoral research experience (in a research laboratory) at the time of application and not be more than five years from his/her PhD; be nominated by a qualified mentor at the degree-granting institution where the applicant will conduct his/her postdoctoral/fellowship training; have secured a postdoctoral position with funding (including support from the mentor's existing research grants) at a degree-granting institution in the United States or Canada; and be an underrepresented member of a minority group (i.e., American Indian or Alaska Native, black or African American, Hispanic, or Native Hawaiian or other Pacific Islander). 

For more information visit the  BWF website .
National Psoriasis Foundation
Application Deadline: January 19, 2018
The National Psoriasis Foundation  Research Program funds and promotes research into psoriatic disease and related comorbidities, under NPF's mission of finding a cure for psoriatic disease and improving the lives of those affected.

Research projects are selected not only for their potential to yield information that may help treat psoriatic disease, but also to answer basic questions about the underlying disease mechanisms, comorbidities, and public health. Applications undergo a rigorous scientific peer-review by a panel of experts and are then selected for funding based on patient input and Foundation priorities. This year the Foundation is offering six different research grant opportunities: Discovery Grants, Translational Research Grants, Early Career Research Grants, Bridge Grants, the 2018 Pediatric Psoriasis Challenge Grant, and Psoriatic Arthritis Research Grants. 

For more informaiton, visit the  NPF webpage .
NCAI Special RFA Announcement
Application Deadline: January 24, 2018
The NCAI announces a special round of funding for high impact diseases from NHLBI.

Desire to fund 4 to 5 projects impacting the following diseases:
  • Chronic Obstructive Pulmonary Disease (COPD)
  • Idiopathic pulmonary fibrosis (IPF)
  • Pulmonary hypertension
  • Heart failure
  • Myocardial infarction
  • Sickle cell anemia
  • Non-statin LDL lowering drugs 

These projects DO NOT NEED an LOI (letter of intent) but instead, they will be invited directly to a full application, which is due on January 24 th .

NCAI/NCIC staff will need to have a discussion with applicants to review fit to this special round. Upon discussion, applicants may be invited to submit a full application.
Early-stage projects are encouraged to apply. Funding is up to $150k (with matching funds from the institution).
 
Please contact Steve Behm for more information:
Stephen M. Behm
University Hospitals
Cleveland, Ohio
(216) 844-1415  (o)
RFP: Barrett's Esophagus Translational Research Network (BETRNet)
Application Deadline: January 31, 2018 at 11:59 PM
All faculty members at participating institutions are invited to submit applications for Individual or Cross-BETRNet pilot projects of up to $40,000 to be funded by NIH/NCI U54CA163060: Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma.  Deadline for submission is January 31, 2018 at 11:59 PM, with funding expected to begin May 1, 2018.

Note: A BETRNet Project must be directed toward translational research related to Barrett’s Esophagus. At least one specific aim should involve either direct patient contact or the study of patient derived tissue samples.


Questions:  BETRNetAdmin@case.edu or 216-368-1674

Michelson Medical Research Foundation
Pre-application Deadline: February 12, 2018
The Michelson Medical Research Foundation (MMRF)  together with the Human Vaccines Project have established the Michelson Prizes for Human Immunology and Vaccine Research. The $20 million initiative, funded by the MMRF and administered by the Human Vaccines Project, aims to support young investigators applying innovative research concepts and disruptive technologies to significantly advance the development of future vaccines and therapies to defeat major global diseases. While the Michelson Prizes are focused on research outcomes in the fields of human immunology and vaccinology, applicants from the full spectrum of related disciplines, including clinical research, biomedicine, artificial intelligence/machine learning, engineering, and nanotechnology are encouraged to apply. Proposals will be reviewed and winners selected by a distinguished committee of internationally-recognized research scientists.

Experience in human immunology or vaccine research is not required; however, the application must focus on human immunology or vaccine research, and the applicant must maintain a 50% dedication of his/her full-time professional effort during the award period to the research funded by this award.

Individuals from other disciplines who will apply novel concepts to human immunology and vaccine research are also encouraged to apply.

The applicant is expected to assemble a research team that will provide the necessary expertise and collaborative efforts toward accomplishing the research goals proposed in the application.

The applicant must be under the age of 35 at the time of pre-application submission (February 12, 2018). Early career independent investigators, postdoctoral fellows, clinical fellows (including residents and interns), and other researchers currently in training positions are eligible for this award. An eligible applicant, regardless of ethnicity, nationality or citizenship status, must be employed by or affiliated with, an eligible organization. Examples of eligible organizations include academia, biotechnology companies, foundations, government and non-governmental organizations, and research institutes. Individuals from such organizations, including organizations based outside of the US, are eligible to apply. Each applicant may submit only one Michelson Prize application per year. Note: The Michelson Prizes for Human Immunology and Vaccine Research will be awarded to individuals, not institutions.

Pre-application Deadline: February 12, 2018
Invited Application Deadline: April 02, 2018

For more information visit the   MMRF website .
Klingenstein Fund
Application Deadline: February 15, 2018
The  Esther A. & Joseph Klingenstein Fund , in partnership with the  Simons Foundation,  has announced the opening of its 2018 competition for research fellowships in the neurosciences.

Previously known as the Klingenstein Fellowship Awards in the Neurosciences, this year's awards are the second from this joint initiative. The awards are presented to highly promising early-career scientists. At a critical juncture in young investigators' careers when funding can be a challenge, the awards are intended to promote higher-risk, and potentially higher-reward, projects.

Payable over three years, the $225,000 award may be used for salary support, research assistants, equipment, or any other purpose that promotes the scientific activities of the fellow.

To be eligible, investigators must hold a PhD and/or MD degree and have completed all their research training, including postdoctoral training. In addition, the applicant must be an independent investigator within four years (between July 1, 2014, and July 1, 2018) of receiving his/her first tenure-track appointment at a university or medical institution. 

For more information visit the  Klingenstein Fund website .
Case-Coulter Translational Research Partnership (CCTRP)
Pre-proposal Deadline: February 28, 2018
The Case-Coulter Translational Research Partnership (CCTRP) is accepting applications for 2018.

The purpose of CCTRP funding is to support collaborative translational research projects that address unmet or poorly met clinical needs. CCTRP seeks to reduce the market risk of promising new clinical products arising from the research programs of biomedical engineering and other Case Western Reserve University faculty.

The request for applications (RFA) and more information about the program can be found at  engineering.case.edu/ebme/cctrp .

All eligibility requirements and deadlines can be found in the RFA. The first deadline is a pre-proposal, which is due Feb. 28. Applicants are encouraged to meet with the CCTRP office during development of their pre-proposal (well before the submission deadline).

Thrasher Research Fund
Concept Paper Deadline: March 13, 2018
The  Thrasher Research Fund  provides grants for clinical, hypothesis-driven research that offers substantial promise for meaningful advances in the prevention, diagnosis, and treatment of children's diseases, particularly research that offers broad-based applications.

The fund is inviting concept papers for its Early Career Awards Grants program. Through the program, the fund awards small grants of up to $25,000 to new researchers to help them gain a foothold in the area of pediatric research. The program will consider a variety of research topics important to children's health but will give priority to applicants who show great potential to impact children's health through medical research. Both an applicant's aptitude and inclination toward research will be considered.

The program is open to physicians who are in a residency/fellowship training program or who completed that program no more than one year before the date of submission of the concept paper, as well as postdoctoral researchers who received the doctoral level degree no more than three years prior to the date of submission of the concept paper.

Invited Proposal Deadline: April 27, 2018

For more information visit the  Thrasher Research Fund website .
Children's Leukemia Research Association
Application Deadline: June 30, 2018
The Children's Leukemia Research Association , also known as the National Leukemia Research Association , was founded in 1965 to support research efforts focused on finding the causes of and a cure for Leukemia. To that end, CLRA is seeking applications from investigators for promising research projects in the area of childhood leukemia.

Grants of up to $30,000 will be awarded to promising projects focused on isolating the causes of and finding a cure for childhood leukemia. Funding from other sources is permissible, but CLRA funding objectives should not duplicate those of other sources.

Any doctor at the PhD or MD level involved in research on finding the causes of and/or a cure for leukemia may apply. 

For more information visit the  Children’s Leukemia Research Association website .
NIH Funding Opportunities & Notices
Multiple Deadlines
BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (U44 Clinical Trial Required)

Self-Management for Health in Chronic Conditions (R01 Clinical Trial Optional)

Community Partnerships to Advance Research (CPAR) (R01 Clinical Trial Optional)

Innovative Questions in Symptom Science and Genomics (R15 Clinical Trial Not Allowed)

Biobehavioral and Technological Interventions to Attenuate Cognitive Decline in Individuals with Cognitive Impairment or Dementia (R15 Clinical Trial Not Allowed)

Effects of In Utero Alcohol Exposure on Adult Health and Disease (R01 - Clinical Trial Optional)

Early-life Factors and Cancer Development Later in Life (R01 - Clinical Trial Not Allowed)

Drug Repurposing for Conditions Affecting Neonates and Pregnant Women (R01 - Clinical Trial Optional)

Discovery of Molecular Targets for Pregnancy-Related/Induced Diseases and Development of Therapeutics to Prevent/Treat These Diseases (R01 - Clinical Trial Optional)

Alzheimer's Clinical Trials Consortium (ACTC) Clinical Trials (R01 Clinical Trial Required)

Human Cell Biology of Alzheimer's Disease Genetic Variants (R01 - Clinical Trial Not Allowed)

NeuroNEXT Clinical Trials (U01 - Clinical Trial Optional)

Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Optional)

Clinical Trial Readiness for Rare Neurological and Neuromuscular Diseases (U01)

Basic and Translational Research on Decision Making in Aging and Alzheimer's Disease (R01 - Clinical Trial Optional)

Analytical Validation of Candidate Biomarkers for Neurological Disease (U01 Clinical Trial Optional)

Partnership for Aging and Cancer Research (U01 - Clinical Trial Not Allowed)