JANUARY 2017
Steroid Responsive Meningitis-Arteritis (SRMA)


SRMA, also known as corticosteroid responsive (aseptic) meningitis is an auto-immune disease that targets the leptomeninges and associated vessels. The exact cause is unknown. Studies have suggested a Th2-mediated response with elevated Immunoglobulin A (IgA) levels in the CSF and serum. Elevated IL-8 levels have been noted in the CSF which is associated with invasion of neutrophils into the leptomeninges.

SRMA is mostly seen in medium to large breed dogs with the Boxer, Bernese Mountain Dog, Beagle, Golden Retrievers, German Shorthaired Pointers and Nova Scotia Duck Tolling Retriever possibly being predisposed. In the Beagle, SRMA was been previously labeled as 'Beagle Pain Syndrome'. Although these breeds seem to be overrepresented with SRMA, it can affect almost any breed of dog. SMRA typically occurs in dogs less than 2 years of age. 



Treatment of a well-differentiated hepatocellular carcinoma with CyberKnife stereotactic radiation therapy
The patient, an 11-year-old FS Golden Retriever, presented to a referral hospital where she was diagnosed with a low grade hepatocellular carcinoma (HCC). The only clinical sign present was an increase in ALT of 137 (reference range ALP 0-120) and ALP of 427 (reference range 0-140) which was found on routine bloodwork. An ultrasound revealed a 13 x 8 cm isoechoic mass occupying the right medial and portions of the right lateral liver lobes. The mass was mostly solid but with an approximately 5 x 6 cm hypoechoic region which appeared cavitated. 


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Growing Use of Intralipid Therapy in Veterinary Medicine
The use of intralipid therapy has been gaining traction as a treatment option for an ever expanding range of toxicities. While it has not quite become the standard of care, it has been viable for patients in the veterinary field and has been reported as case studies in the human field.

Veterinary literature has reviewed intravenous lipid emulsion therapy (ILE) [1,2] and published case reports or studies are available noting efficacy in toxicities including macrocyclic lactones [3,4], baclofen [5], beta-blockers, calcium channel blockers [6], NSAID [7,8], bromethalin [9], lidocaine [10], permethrin toxicity [11,12], tricyclic antidepressants (13). Intravenous lipid emulsion (ILE) 

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New cancer drug for dogs
The U.S. Food and Drug Administration announced Tuesday that it's given conditional approval for  the first new animal drug to treat canine lymphoma. Also called lymphosarcoma, lymphoma is a type of cancer in dogs. The FDA said the active ingredient in Tanovea-CA1 is rabacfosadine, a substance that kills rapidly growing cancer cells.
 
Lymphoma  can affect virtually any organ in the body, but  it most commonly starts in organs that function as part of the immune system, such as the lymph nodes, spleen, and bone marrow. The signs of lymphoma in dogs vary depending on which organs are affected.


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New treatments for dogs' skin problems
Itchy pets are one of the top reasons for visits to a veterinarian. In spring, summer and fall, many dogs and cats are scratching and chewing themselves. We see fewer itchy dogs in winter, but the cycle of dermatology cases never really stops.

Cats are easier to treat than dogs. Some dog breeds are particularly prone to skin problems. If food sensitivity is part of the allergic response, the veterinarian may suggest diet trials. Some pets respond to food changes, but often skin testing is needed to reveal what other allergic antigens are causing problems.

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Tackling Osteosarcoma in People and Pet Dogs
Dogs and people have lived side-by-side for thousands of years. So it should come as no surprise that dogs and their people have much in common. Unfortunately, the shared experiences of our two species include a considerable risk of developing cancer at some point in our lives. In fact, dogs and people often suffer from cancers that are remarkably similar at the biological level. Take osteosarcoma, for example, a devastating form of bone cancer.
UPCOMING CE EVENTS
CE in the CITY- Focus on: Dermatology
            Date: Sunday April 2, 2017
            Location: WHYY Studios, Independence Mall, Philadelphia, PA
            Credits: 5 hours RACE CE
            RSVP: https://ceinthecity2017.eventbrite.com

Lehigh Valley Spring Symposium
            Date: Sunday April 30, 2017
     Location: Bear Creek Mountain Resort and Conference Center 
     Credits: Pending 4 hours CE- PVMA
     RSVP:   https://lehighvalleyveterinarysymposium.eventbrite.com

SAVE THE DATE!

PVMA District 8 Meeting: Minimally Invasive Surgery with Hope VS
     Date: Thursday April 27, 2017
     Location: TBD, Reading, PA 
     Credits: Pending 1.0-1.5 hrs CE- PVMA
     RSVP: Stay Tuned!  

Veterinary Sports Medicine Symposium
           Keynote:  Joseph J. Wakshlag, DVM, PhD, DACVN, DACVSMR- Cornell University
           Date: Sunday August 27, 2017
           Location: TBD Wilmington, DE
           Credits: Pending 4-5 CE credits
           RSVP:   https://hopevssportsmedicine.eventbrite.com

Veterinary Surgical Oncology Symposium
           Keynote: Sarah Boston, DVM, DACVS
           Date: Sunday, November 5, 2017
           Location: Normandy Farms, Blue Bell, PA
           Credits: Pending 4-5 CE credits
           RSVP:   https://hopevssurgicaloncology.eventbrite.com