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Ketone Bodies Neutralize Harmful Metabolite of Glucose Metabolism
   
Ketosis occurs when the body utilizes ketone bodies (acetoacete, β-hydroxybutyrate and acetone), byproducts of fatty acid metabolism, as the main energy source instead of glucose
 
A recent article published in Cell Chemical Biology demonstrates a novel biological function for ketone bodies: neutralizing methylglyoxal (MG), a highly reactive metabolite of glucose metabolism. MG is involved in aging- and diabetes-related pathologies

Roundtable Insights on Inflammation: Fish Oils vs. SPMs
What's the Difference?
In a series of discussions on inflammation, Dr. Robert  Martindale, MD, PhD moderates an insightful conversation with experts Drs. Stephen McClave, PhD, 
Jesmond Dalli, PhD, and Todd Rice, MD

Listen along and you will gain fluency on the differential roles of marine-based omega-3 fatty acids vs. specialized pro-resolving mediators (SPMs) in mitigating and resolving inflammation

Metabolism of Exogenous Ketones in Humans
Clinical Tool

Endogenous ketosis is a metabolic state resulting from prolonged fasting, exercise or when consuming a ketogenic diet (KD). In contrast, when acute ketosis is achieved by consumption of ketone supplements, it is referred to as exogenous ketosis. There is  growing interest to develop palatable exogenous ketone products in the ketone salt (KS) or ketone ester (KE) forms and to understand their metabolic effects in humans

In a recent publication by Dr. Brianna Stubbs and colleagues published in Frontiers in Physiology , the authors investigated the differential effects of KS and KE drinks on blood levels of beta-hydroxybutyrate and metabolites, in addition to the ketosis-inducing efficacy of KE following meal ingestion

Webinar Series with Michael Nova, MD, PhD: Targeted Nutrition
Part 3: Overview of Epigenetics

Continue with part 3 of this 4-part webinar series with Dr. Michael Nova, MD, PhD, as he provides an overview of epigenetics, exploring how the expression of our genes is influenced by external factors
 
Epigenetic mechanisms of histone modification and methylation are discussed, as well as cell- and tissue-specific effects of genes, with a particular focus on cancer cells and anti-tumor epigenetics therapy
 

Access Part 2: Deeper Dive into Nutrigenomics   click here
Access Part 1: Nutrigenomics and Precision Medicine  click here

Registered Dietitians and Functional Nutrition Specialists interested in continuing education can receive 1 IFNA continuing education credit by listening to this or any podcast or webinar on Metagenics Institute


*All CE is complimentary to registered MHICN users

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