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VIDEOS: Identify. Quantitate. Any Molecule. | Thermo Scientific Triple Quadrupole
Captured live at ASMS 2012 in Vancouver, Canada, Shane Tichy highlights the Thermo Scientific TSQ Triple Quadrupole mass spectrometer that enables the quantitation and confirmation of compounds in complex matrices. Learn about the TSQ Series of triple stage quadrupoles systems and find the right LC/MS solution for your lab from the value-conscious TSQ Quantum Access MAX LC/MS to the precise TSQ Vantage LC/MS. See how our mass spectrometers couple perfectly with HPLC, UHPLC, and nano LCs to create a robust analytical system including software.
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PODCASTS: 1st Hand Access to Research: William Gunn, Mendeley
William Gunn is head of academic outreach for Mendeley, the new tool for sharing research that everyone is talking about. Introducing us to the concept of altmetrics, William presents the Mendeley desktop manager and other features of Mendeley which separate it from Google Scholar. Mr. Gunn discusses his vision for the future of open access publishing and shares a personal story of evacuating New Orleans during Katrina.
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REVIEWS: Moving Towards Real-Time Imaging in Single, Living Cells
The latest issue of DECODED, Integrated DNA Technologies' (IDT's), quarterly newsletter, highlights the use of IDT oligos to image RNA in single, living cells. Dr Tsourkas, Associate Professor of Bioengineering at the University of Pennsylvania, has ordered oligos from IDT for over 10 years, collaborating with the company to design several types of molecular imaging agents.
By combining Molecular Beacons (MBs) with small interfering RNA (siRNA), Dr Tsourkas' group has created an all-RNA probe, termed the Ratiometric BiMolecular Beacon (RBMB). Delivered using microporation, the siRNA portion guides localization of the RBMBs to the cell cytoplasm, where they bind to specific mRNAs. These imaging agents make it possible not only to track and visualize individual RNA transcripts, but allow researchers to actually see cell trafficking, measure the velocity of transcript movement, monitor localization within the cytosol, and visualize RNA from transcription through translation.
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BLOGS: Picture Blog - Human mRNA-Induced Pluripotent Stem Cells Generated in Days
What phenotypic changes can be observed during a successful reprogramming trial?
R-iPS Cell FAQ 1:
What phenotypic changes can be observed during a successful reprogramming trial?
About one week out, target fibroblasts should show an involution of fibroblastic processes, and foci or clusters of epitheliod cells ideally with small nuclei, minimal cytoplasm, and signs of ongoing mitosis should appear. Colonies with hESC morphology typically start emerging in ~10-14 days.
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 Original Manufacturer Product Manager Life Sciences R&D Manufacturing at Pharma-Cruiting Life Sciences Executive Search... more>>
Research Scientist II Organic Surface Chemist at Phenomenex... more>>
Research Scientist I Sol-Gel Chemistry at Phenomenex
... more>>
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BIT's 2nd Annual World Congress of Microbes-2012
30 Jul 2012 to 01 Aug 2012
Guangzhou, China
more>> |
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CHI's Next Generation Dx Summit: Moving Assays to the Clinic
21 Aug 2012 to 23 Aug 2012
Washington, DC
more>> |
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Genomics Research Europe
04 Sep 2012 to 05 Sep 2012
Sheraton Frankfurt Airport Hotel, Hugo-Eckener-Ring 15 Rhein, Main Airport, 60549, Frankfurt, Germany
more>> |
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Differences between human twins at birth highlight importance of intrauterine environment
Your genes determine much about you, but environment can have a strong influence on your genes even before birth, with consequences that can last a lifetime. In a study published online in Genome Research, researchers have for the first time shown that the environment experienced in the womb defines the newborn epigenetic profile, the chemical modifications to DNA we are born with, that could have implications for disease risk later in life. more>> |
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Critical cell in fighting E. coli infection identified
Despite ongoing public health efforts, E. coli outbreaks continue to infiltrate the food supply, annually causing significant sickness and death throughout the world. But the research community is gaining ground. In a major finding, published July 15 in the scientific journal Nature, researchers from the La Jolla Institute for Allergy & Immunology have discovered a molecule's previously unknown role in fighting off E. coli and other bacterial infections, a discovery that could lead to new ways to protect people from these dangerous microorganisms. more>> |
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Bringing HIV Out Of Hiding
The synthesis of analogs of a bryostatin natural product could advance the eradication of AIDS by ferreting HIV out of its hiding places in immune cells. more>> |
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Discovery of chemical that affects biological clock offers new way to treat diabetes
Biologists at UC San Diego have discovered a chemical that offers a completely new and promising direction for the development of drugs to treat metabolic disorders such as type 2 diabetes -- a major public health concern in the United States due to the current obesity epidemic. more>> |
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Mutation in gene IDH a possible target for AML treatment
Many patients with acute myeloid leukemia (AML) share a mutation in a gene called IDH. A University of Colorado Cancer Center study published this week in the journal Leukemia & Lymphoma shows that this IDH mutation may be the first domino in a chain that leads to a more aggressive form of the disease. more>> |
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FROM LABROOTS:
Have a wonderful week!
Sincerely,
The LabRoots Team
www.LabRoots.com |
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Copyright © 2011 LabRoots, Inc.
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