New York News in Research: February 2018
SUNY Upstate Medical University: Researchers Use Synthetic Protein to Disrupt Work of Bacteria

A synthetic protein that disrupts the ability of bacteria to perform basic life functions-moving, eating, attaching to hosts-could be a key to fighting infectious disease and preventing bacteria from evolving into drug-resistant pathogens.  Take a closer look.
Stony Brook Medicine: New Drug Target Emerges for Dangerous Fungal Pathogen
Cryptococcus neoformans is a fungal pathogen usually affecting immunocompromised patients, particularly AIDS and organ transplant patients, and is one that can be lethal. Current treatments against cryptococcosis are often not effective.  Take a closer look.
Weill Cornell Medicine: How Cancer Metastasis Happens - Researchers Reveal a Key Mechanism

Cancer metastasis, the migration of cells from a primary tumor to form distant tumors in the body, can be triggered by a chronic leakage of DNA within tumor cells, according to a team led by Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center researchers.  Take a closer look.
Columbia University Vagelos College of Physicians and Surgeons: New-Infrared Light May Identify Breast Cancer Patients Who Benefit Most From Chemotherapy 
A new optical imaging system developed at Columbia University uses red and near-infrared light to identify breast cancer patients who will respond to chemotherapy. The imaging system may be able to predict response to chemotherapy as early as two weeks after beginning treatment. Take a closer look.
University of Rochester School of Medicine and Dentistry: HPV May Lurk in Your Throat
Human papilloma virus (HPV), the culprit behind cervical cancer and some forms of head and neck cancer may hide in small pockets on the surface of tonsils in people not known to carry the virus. The finding, reported by University of Rochester Medical Center researchers in the Journal of the American Medical Association - Otolaryngology, could be pivotal for the prevention of oropharyngeal cancers that form on the tonsils and tongue.  Take a closer look.
Albert Einstein College of Medicine: Previously Unknown Ocean Virus Family May Also Populate the Human Gut

A newly discovered family of viruses appears to play a major role in killing marine bacteria and maintaining the ocean's ecology. Preliminary evidence suggests that related bacterial viruses also occur in the human gut. The study, by researchers at Albert Einstein College of Medicine and Massachusetts Institute of Technology (MIT), was published online on January 24 in the journal Nature.  Take a closer look.
NYU School of Medicine: Nerve Networks for Walking Originated in Ancient Fish

The nerve circuits that enable people to walk first appeared more than 400 million years ago in fish whose descendants still walk the seafloor on their fins. This is the finding of a study led by researchers from NYU School of Medicine and published online February 8 in the journal Cell.  Take a closer look.
Weill Cornell Medicine: Enzyme Digests Amyloid-Beta Associated With Alzheimer's Disease

An enzyme found in brain cells can break apart the precursors to plaques that accumulate in the organ and cause toxicity in Alzheimer's disease, according to a new study led by Weill Cornell Medicine scientists.  Take a closer look.

Columbia University Vagelos College of Physicians and Surgeons: New Insights Into How Neurons Become Mature and Excitable 
Neurons, or nerve cells, in the brain communicate with each other by transmitting electric signals, or firing action potentials, through long processes named axons (which send out signals) and dendrites (which receive signals). Take a closer look.
Other Studies
Icahn School of Medicine at Mount Sinai: Machine Learning Techniques Generate Clinical Labels of Medical Scans

Researchers used machine learning techniques, including natural language processing algorithms, to identify clinical concepts in radiologist reports for CT scans, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published in the journal Radiology. Take a closer look.
University of Rochester School of Medicine and Dentistry: In Wine, There's Health: Low Levels of Alcohol Good for the Brain
While a couple of glasses of wine can help clear the mind after a busy day, new research shows that it may actually help clean the mind as well.  The new study, which appears in the journal Scientific Reports , shows that low levels of alcohol consumption tamp down inflammation and helps the brain clear away toxins, including those associated with Alzheimer's disease Take a closer look.
New York Institute of Technology College of Osteopathic Medicine: Researchers Go Toe-to-Toe With Horse Evolution

Scientists have long wondered how the horse evolved from an ancestor with five toes to the one-toed animal we know today. While it is largely believed that horses simply evolved to have fewer digits, Nikos Solounias, Ph.D., professor in NYIT College of Osteopathic Medicine(NYITCOM) poses a new theory that suggests remnants of all five toes are still present.  Take a closer look.
Icahn School of Medicine at Mount Sinai: Researchers Find Grape-Derived Compounds Capable of Promoting Resilience Against Stress-Induced Depression

In a study to be published online February 2 in Nature Communications, scientists from the Icahn School of Medicine at Mount Sinai describe an extensive analysis of novel grape-derived compounds, dihydrocaffeic acid (DHCA) and malvidin-3'-O-glucoside (Mal-gluc),which might be developed as therapeutic agents for the treatment of depression Take a closer look.
Albany Medical College Receives $1.9 Million From NIH for Studies on Flu Complications

Albany Medical College researchers are investigating new ways to prevent severe illness and death due to influenza and the secondary bacterial infections that can occur in its wake.  Take a closer look.
New York Medical College: Empire State Development Awards BioInc@NYMC More Than One Million Dollars

BioInc@NYMC, New York Medical College's flourishing biotechnology incubator, has received 1.25 million dollars awarded by Empire State Development (ESD) and the Mid-Hudson Regional Development Council (REDC) to support the school's commitment to fostering innovation and prosperity in the Mid-Hudson region and its operations as a New York State-designated Innovation Hot Spot. The award follows earlier ESD awards in which the REDC recognized BioInc@NYMC as a regional priority and is the second largest award in the region this year.  Take a closer look.
Albany Medical College Receives $450,000 Grant for Metastatic Breast Cancer Research

An Albany Medical College researcher has received a $450,000 Susan G. Komen grant to study whether specific proteins play a role in enabling the spread and subsequent growth of breast cancer cells in the body and whether these proteins may offer clues to potential treatments to extend survival rates.  Take a closer look.
New York Medical College: Prominent Trauma Surgeon Addresses 14th Annual Louis R.M. DelGuercio Professorship and Research Day

John A. Savino, M.D., left, the Felicien Steichen Professor and Chairman of the Department of Surgery, and Rifat Latifi, M.D., right, professor of surgery, director of the Department of Surgery and program director of the Surgical Critical Care Fellowship, welcomed prominent trauma surgeon, George C. Velmahos, M.D., Ph.D., M.S.Ed. , as the keynote speaker of the 14th Annual Louis R.M. DelGuercio Professorship and Research Day on December 13.  Take a closer look.