March 2018
News
TriNetX Develops Algorithm for Deducing the Chemotherapy Line of Treatment a Patient is Undergoing
TriNetX, the global health research network representing nearly 100 million patients, has developed a groundbreaking chemotherapy lines of treatment identification algorithm that understands treatment patterns to deduce the line of chemotherapy treatment a patient is undergoing. This information, up to now nearly impossible to obtain, is critical for biopharmaceutical companies striving to develop therapies for patients involved in care regimens beyond first line treatments.

“Being able to identify which line of chemotherapy treatment corresponds to which subset of a patient’s data is truly a breakthrough in oncology data analytics,” said Jack London, Informatics Research Professor and Informatics Director, Sidney Kimmel Cancer Center, Thomas Jefferson University. “This type of information is not tracked in traditional EMRs or any other system today. The ability of TriNetX to deliver this data provides huge benefits for both biopharma companies and healthcare organizations in their data driven analyses.”

Jeno Mozes  is the TriNetX liaison for the CTSC . TriNetX is a global health research network enabling healthcare organizations, biopharma and contract research organizations (CROs) to collaborate, enhance trial design, accelerate recruitment and bring new therapies to market faster. Through TriNetX, healthcare organizations can attract clinical trials, collaborate with peers, enhance local research. Researchers can participate in multi-site research with other healthcare organizations without having to expend precious resources to normalize their data to an external standard.
Request for Applications: Center for SUDEP Research Pilot Program
Application Deadline: March 14, 2018
The  Center for SUDEP Research   (CSR) has been established to study Sudden Unexpected Death in Epilepsy (SUDEP). This Epilepsy Center Without Walls includes over 40 clinicians and scientists from 14 institutes across the U.S. and U.K. This five-year research initiative is supported by the National Institute of Neurological Disorders and Stroke at the National Institutes of Health (NIH) and brings together many of the leaders in the field of SUDEP research. The current grant RFA is generously funded by UCB.

SUDEP is the sudden and premature death of a person with epilepsy without apparent or known cause of death. It is the most common cause of premature mortality for people with epilepsy. Individuals with refractory epilepsy have a 35% lifetime chance of succumbing to SUDEP. There are currently no targeted treatments or devices available to prevent it. The cause of SUDEP is unknown, but research efforts have centered on structural and/or functional defects in brain areas that control cardiovascular and respiratory functions. Such abnormalities can cause breathing and heart rate disruptions following a seizure, which in a subset of cases, are catastrophic and lead to sudden death.

The CSR seeks novel pilot projects that will address the goal of understanding and eliminating SUDEP. This pilot program will award grants to national and international researchers submitting innovative proposals that compliments and expands on the SUDEP research proposed in the CSR. The CSR plans to support one clinical pilot project (clinical trials will not be funded through this mechanism, but studies involving human subjects are allowed) and one basic research project. Infrastructure building applications are discouraged and applications need to have robust scientific hypotheses. Utilizing current existing CSR Cores and expertise is strongly recommended. Successful applicants will be expected to work collaboratively with the CSR investigators.

First Annual Community Research Dissemination Forum
Tuesday, March 27, 2018, 5:30 pm - 7:30 pm
Cleveland Botanical Garden
Join the Center for Reducing Health Disparities as we launch our new National Institutes of Health (NIH) grant: “Involving Communities in Delivering and Disseminating Health Disparity Interventions”.

Please RVSP no later than Friday, March 16, 2018.

For questions or more information, please contact Jacqueline Dolata at

Dahms Clinical Research Unit (DCRU) Analytical Laboratory
Do you have questions about best practices for research sample collection, processing, storage and analysis? If so, let us help!  The DCRU Analytical Core Laboratory provides consultation for and testing of research assays.  Using enzyme linked immunosorbent assays (ELISA), we test serum, plasma, saliva, urine, CSF and breast milk (and other sample types) for a variety of different analytes. Sample dilutions will be performed when appropriate.

This is a research lab with a clinical emphasis. We operate under a GLP-based quality model. Freezers, centrifuges, bio-safety hood and pipettes undergo routine maintenance and calibration.  Our quality control plan requires at least 2 levels of manufacturer’s/in-house quality controls be run in each assay and results are thoroughly reviewed before released.  If we know many assays will be run on one sample, we maintain the integrity of the samples by making additional aliquots and limiting freeze-thaw cycles.

Assay Validation testing can be performed including dilution, sensitivity, precision and accuracy testing to assure kit performance. Other services offered in conjunction with the DCRU Sample Processing lab include DNA and PBMC extraction and long term sample storage and tracking in 24/7-monitored -70 freezers. To request more information about our fee-for-service analytical and sample storage services, contact Sarah Scott ( sarah.scott@uhhospitals.org ).
Working at the University-Industry Interface: Effective Strategies for Active Researchers
Wednesdays, February 7 through May 2, 2018
1:00 pm-2:15 pm
Sears Library Building, Room 642
A shifting landscape of federal research funding and declining corporate research and development budgets make university and industry partnerships highly attractive for both sides; however, opposing values and interests can make such partnerships especially tricky to manage.

Join us for a series of webinars that will guide you through the nuances and complexities of these research partnerships. Over seven sessions, we’ll carefully cover the most critical considerations for creating win-win relationships.

You can’t effectively learn about successful partnerships unless you can hear from both sides. This is a unique opportunity to gain access to insights and best practices from leading experts at research universities and leading global corporations. They’ll leverage the unique perspective of University-Industry Demonstration Partnership’s (UIDP) research and best practices, as well as their own personal experience.

Session 3: Establishing Contacts with Industry and Research Institutions and Dealing with Confidential/Proprietary Information
Wednesday, March 7

Session 4: Preparing Proposals and Budgeting
Wednesday, March 21

Session 5: Addressing Compliance, Contracting and Consulting, and Outside Activities
Wednesday, April 4

Session 6: Managing Intellectuals Property (IP) Issues
Wednesday, April 25

Session 7: Benefiting from University-Industry Collaborations with Government Engagement
Wednesday, May 2

For more information about the webinars:   click here .

The Clinical Research Scholars Program (CRSP - Master's in Clinical Research) Seeks Help Filling Leadership Roles
Teach CRSP 402 Study Design and Epidemiologic Methods: This 3 credit hour course covers the methods used in the conduct of epidemiologic and health services research. The course begins with how to quantify disease frequency and compare it across populations, often as a way to generate hypothesis about what factors may cause a given condition. The course will introduce methodologic issues that need to be considered in the design and conduct of epidemiologic studies, including classification of disease and exposure status, types and consequences of misclassification, effect modification and related concepts. Additional sessions will focus on the control of confounding and on the three main types of study designs: randomized trials, cohort studies and case-control studies. Topics include: Measures of disease frequency, measures of effect, classification and misclassification, cross-sectional studies, case-control studies, cohort studies, randomized controlled trials, confounding, bias, effect modification and select topics.

For the last several years, the course has met on Mondays and Wednesdays 9-11am for approximately 8 weeks, but this could be changed depending on the instructor and student schedules/preferences. A more traditional schedule is acceptable.

Coordinate the CRSP Capstone project , a requirement for the modified “Type B” (non-thesis) Master’s degree, which has been designed for individuals with bachelor’s degrees who are not Cleveland Clinic Lerner College of Medicine students. The purpose of the Capstone is to provide hands-on experience in conducting clinical research. The project will consist of approximately 160 hours over the course of a semester, typically 20 hours per week for 8 weeks, and the student will enroll in the 3 credit hour CRSP 650 (to be created) or CRSP 601 Research Practicum. The Capstone project may take diverse forms: (1) A study project; (2) A combination of tasks necessary for the successful implementation of a study, such as attending team meetings, developing an IRB protocol, designing study forms, assisting with recruitment, study procedures, data management/cleaning, descriptive analysis, secondary analysis; (3) Another format, with approval of CRSP director and Capstone Advisor.

The key tasks would be to:
  1. Identify potential Capstone projects and advisors, and link MS students with the advisor.
  2. Provide overall oversight of Capstone component of the CRSP

To coordinate the Capstone effectively, we are seeking an individual with the following qualifications:
  1. Well connected with the clinical research community in greater Cleveland (e.g., CWRU, University Hospitals, Cleveland Clinic, MetroHealth Center, the Louis Stokes VA. 
  2. MD or PhD degree
  3. Substantial experience in conducting research
  4. The salary support is negotiable, up to a maximum of 25% for both teaching 402 and coordinating the Capstone project.

If interested, please contact Mendel Singer (216-368-1951) or
Jim Spilsbury (216-368-7559)
Health Informatics Update from the
Institute for Computational Biology
ICB at Research ShowCASE
The ICB will again have a booth at Case Western Reserve University’s Research ShowCASE which will be held on Friday, April 20, 2018 from 9:00a.m.-3:00p.m. in the Veale Convocation Center. Members of the ICB will be available to discuss current initiatives, offerings, and collaborations. In addition, the ICB will also have several posters on the main floor highlighting past and present research collaborations as well as technologies currently being implemented, such as EMERSE (the Electronic Medical Record Search Engine). The ICB booth will next to the UTech (University Technology) booth this year, as many of the ICB offerings are dependent upon and are complemented by UTech infrastructure and services, such as the SRE (Secure Research Environment) and the HPC (High Performance Computing cluster). More information about Research ShowCASE can be found here: http://case.edu/research/showcase/.
ICB Job Openings
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The ICB is currently accepting applications for an assistant director for projects, data governance and compliance, as well as for a biomedical and patient-centric data modeler and ETL specialist, a data developer and, finally, a web application developer. More information regarding these positions is available here:  ICB Open Positions.
News from the PRCHN
PRCHN Monthly Seminar Series
Mark your calendars for these upcoming PRCHN seminars:

March 14, 2018
Lessons Learned from a Statewide Collaboration to Build Capacity for Obesity Prevention (BCOP)
Darcy Freedman, PhD, MPH, Eunlye Lee, PhD, David Ngendahimana, MStat, Prevention Research Center for Healthy Neighborhoods; Ana Claudia Zubieta, PhD, Ohio State University SNAP-Ed 

April 11, 2018
Chronic Disease Self-Management Program: Innovations and Partnerships to Make a Difference in Self-reported Outcomes
Anna Thornton, MPH, REACH Project Manager; Jonathan Lever, MPH, Better Health Partnership; and Samantha Smith, MA, Cuyahoga County Board of Health

Seminars are held the second Wednesday of each mo nth from 12:00-1:15 pm in the PRCHN Ground Floor Conference Room, BioEnterprise Building, 11000 Cedar Avenue. Parking is available and a light lunch is served.  
 

National Teen Dating Violence Infographic from YRBS
The latest infographic from the  Youth Risk Behavior Survey (YRBS)  team incorporates local data from the 2017 YRBS around National Teen Dating Violence Awareness Month.

The YRBS team is using the 2017 high school data set to create and share a monthly infographic that aligns with national health observances.

Summer 2018 Internship Opportunities
The PRCHN is now accepting Summer 2018 Internship Applications. The program is seeking undergrads and grad students who wish to gain experience in public health research. There are many projects and initiatives at the PRCHN offering interns a variety of experiences including:
  • ground truthing
  • food retail audits
  • field data collection
  • environmental surveillance
  • data entry
  • data analysis (depending on skill level)

Specific intern duties will vary based on placement, but interns will also have the opportunity to gain an overview of all the research and surveillance conducted at the Center.
 
News from the Urban Health Intiative
New Report Highlights Opportunity for Cleveland to Become a World Leader in use of Artificial Intelligence (AI) for Addressing Health Disparities
Scholars from Cleveland State University recently published "The Healing Economy: An Economic Development Framework for Cleveland" . As cost drives consolidation in health care akin to “The Healthcare Hunger games,” the report asks whether health can become to Cleveland what tech is to Silicon Valley? As Pittsburgh utilized robotics expertise at Carnegie Mellon University to transition from steel to autonomous vehicles, could Cleveland apply AI to digitized health information—building off successes in Explorys and IBM Watson, to improve productivity in health care? More significantly, the report posits that Cleveland could leverage its “first mover advantages” by strategically deploying its considerable assets in translational research to “artificial intelligence of population health, particularly the AI of disparities.”   The authors believe that the excessive morbidity, mortality and health disparities in our region should be viewed as a potential, rather than a liability—offering a “proving ground” to create and test a model whereby technology corrects, rather than drives disparities. It is now well accepted that health care only explains 20% of variation in health outcomes. Cleveland should leverage its AI capacity to understand and address the other 80% of factors affecting health outcomes. This should become our product and export.

In summary, the report notes:
  • “Due to regional assets, Cleveland can be a global node in population health research, in effect developing a data capital and AI/machine learning ecosystem that creates leading knowledge in the social determinants of health and reduction of health disparities.
  • A systematic, Cleveland-based intervention to reduce health disparities can be exported globally, igniting a tradable healthcare model that goes beyond selling services outside the region. This is a new type of economic development model operating as a global-local feedback loop. Here, the global export is the health of the local community.”

These words rang very true to us at Health Data Matters. In fact, the vision behind Health Data Matters was to create a resource whereby real-time access to data on health outcomes and the social determinants of health would foster the creation of apps, technology, and health care solutions that would improve population health and reduce disparities.

We have strategically used the Community Health & Wellness Track of the Cleveland Medical Hackathon , and the Cleveland Public Health Innovation Meetup Group as places to develop and test such applications. As always, we welcome your involvement!

Other work outside of Health Data Matters is a step ahead of this report—anticipating the likelihood that algorithms built on data generated only by those who are digitally connected will not wind up being effective with the significant fraction of the population that is not digitally connected. This work, centered at MetroHealth System, and conducted in partnership with Ashbury Senior Computer Community Center , will be a focus of several sessions at the Net Inclusion 2018 Summit, to be held in Cleveland April 17-19, 2018.
Amy R. Sheon , Ph.D., M.P.H.
Executive Director, Urban Health Initiative
Case Western Reserve University School of Medicine
216-368-0915
@CLEhealthCUY
Health Data Matters Team Wins Internet of Things Planning Grant
A team led by HDM Co-Director, Dr. Scott Frank, together with individuals from the Mandel School, Law School and Engineering School, and with HDM team members Amy Sheon, Matthew Kucmanic and Becky Gray (from Cuyahoga County Board of Health) received one of six planning grants for an effort to explore the feasibility of using listening devices (e.g. Amazon Echo or Google Home) to help underserved populations. The grants are part of the University’s new Institute for Smart, Secure and Connected Systems (ISSACS). ISACCS will help the university leverage its strengths in sensors and electronics, networks and communications systems and control, data science and analytics, and other related technology fields to operate on the leading edge of this rapidly growing area of research and opportunity. Stay tuned for further updates including open forums to engage campus and community members.
Upcoming Digital Health Events
See below for more details about this and other upcoming events featuring our work:

March 7, 2018
Las Vegas, NV
Presentation of the Digital Medicine Pilot Registry Study by Amy Sheon

March 16, 2018
San Francisco, CA
Proposal for a work group focused on the digitally disconnected, presented by Dana Crawford

April 5-6, 2018
Cleveland, OH
Panel discussion on precision public health, led by Scott Frank, and hands on with Health Data Matters, led by Amy Sheon

April 17-19, 2018
Cleveland, OH

         
          

June 11-12, 2018
San Francisco, CA
  • Panel 1: Analyzing the Reliability, Differences, and Effectiveness of FDA medical Devices versus Consumer Gadgets, panel discussion with Amy Sheon
           
  • Panel 2: Consumer Engagement, Education and the Proper Understanding of AI Products, panel discussion with Amy Sheon
News from our Colleagues
Tools and resources are provided to assist institutions in joining SMART IRB and to help IRB and HRPP representatives and study teams develop processes and procedures for using SMART IRB for their studies.
Computational Genomic Epidemiology of Cancer
Postdoctoral Training Program
The Case Comprehensive Cancer Center at Case Western Reserve University invites applications to its 2-3 year NCI-funded postdoctoral training program. This program is designed to prepare trainees for careers as independent investigators engaged in research at the intersection of cancer research, genetics, epidemiology, biostatistics and computer science. Cancer researchers obtaining training will have the skills vital to decipher the complex pathways comprising genetic and environmental risk factors for disease, and will ultimately be able to provide clinicians and their patients with valuable information for the prevention and treatment of cancer.

Requirements:
  • US citizenship or permanent residency.
  • Terminal degree (PhD, MD or MD/PhD).
  • Demonstrated skills in quantitative analysis and an interest in a career in genetics research.

In employment, as in education, Case Western Reserve University is committed to Equal
Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.

For More Information:
Contact Damian Junk, 216.286.9191, damian.junk@case.edu
Advocacy & Policy News Updates from the Coalition of Clinical & Translational Science
The beginning of February was a productive and hectic time for lawmakers on Capitol Hill. Following months of protracted negotiations, lawmakers reached a bipartisan budget deal. Click here to continue reading...

Visit the Clinical Research Forum website to stay current on CCTS news!
NIH Extramural Nexus
Research Highlights
Researchers Uncover how Cancer Stem Cells Drive Triple-Negative Breast Cancer
Cleveland Clinic researchers have published findings in  Nature Communications  on a new stem cell pathway that allows a highly aggressive form of breast cancer - triple-negative breast cancer - to thrive.

The new study, led by Justin Lathia, Ph.D., and Ofer Reizes, Ph.D., identifies a never-before described survival pathway in cancer stem cells that may serve as a potential target for new triple-negative breast cancer therapies.

"Triple-negative breast cancer is resistant to treatment and has a high recurrence rate," Reizes said. "This aggressive subtype accounts for about 15-20 percent of breast cancers. Our findings are at an early stage but we are hopeful that targeting these cancer stem cells will lead to new treatments to allow women to be treated successfully and improve their outcomes."

KL2 Scholar Explores a Physician's Duty to Warn in Age of Social Media
Kavita Arora, an assistant professor of reproductive biology and bioethics for the School of Medicine, co-wrote a piece for STAT titled “ An ultrasound on Instagram suggested the baby could be in danger. Does a physician have a duty to warn?

Arora and her co-author discussed the recent situation in which HGTV personality Joanna Gaines was diagnosed by a physician on Instagram. The post featured a video of an ultrasound, which prompted a physician to diagnosis her fetus with a fatal condition. Arora explored the duty of a physician to warn, bodily autonomy and standards of bioethics in the social media age.

Better Health Partnership Work Leads to Huge Health Care Savings for Cleveland Residents
A new Health Affairs study links nearly $40 million in savings over six years to the work of Better Health Partnership , a Cleveland-based regional health care improvement collaboration of primary care providers and other stakeholders.

The savings come from avoided hospitalizations by providing better care to primary care patients with diabetes, high blood pressure and heart failure, according to the study published in the February issue of Health Affairs and conducted by researchers at the Case Western Reserve University-MetroHealth System Center for Health Care Research and Policy.

"You take good care of them in the outpatient setting, and it's (a) much lower likelihood that they would need hospitalization for, for example, amputation in diabetes or kidney failure or recurrence of heart failure," said Dr. Randall Cebul, an emeritus professor of medicine and of population and quantitative health sciences in CWRU School of Medicine.

KL2 Scholar Alumna Offers Strategies to Creating Heart-Healthy Habits
When it comes to our heart, we often know what we need to do in order to stay healthy.

Take the  tips shared by Harvard Health Publishing , for example: avoid tobacco, be active, aim for a healthy weight, improve your diet and drink alcohol in moderation or not at all.
Many of these suggestions may not come as a surprise—but accomplishing them is often more challenging.

“We have to use strategies to help us to implement what we know we should do,” said Mary Dolansky, associate professor at the Frances Payne Bolton School of Nursing.

Noteworthy Research
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Events
2nd An nual Cancer Disparities Symposium:
"Taking it to the Streets: Where Cancer Disparities Research and Community Intersect"
March 23, 2018
Wolstein Research Building - CWRU Campus
This event will showcase cutting-edge research, with a focus on reducing and eliminating disparities in cancer, going from bench-to-bedside-to-community and back. This important symposium will also feature two keynote addresses, including a key leader in our community, and an internationally-recognized cancer disparities researcher. This event will promote the exchange of ideas and collaborative opportunities among scientists, clinicians, government, and community representatives.

This event is FREE to attend, but pre-registration is required. 
Cleveland Health IT Summit
March 27-28, 2018
Hilton Cleveland Downtown
Renowned leaders in U.S. and North American healthcare gather throughout the year to present important information and share insights at the Healthcare Informatics Health IT Summits.

Back for 2018 - the Health IT Summits will feature a full day of cybersecurity education sessions.  This unique program built into the Health IT Summit Series will bring together leading security professionals and executives from provider organizations to discuss the latest trends and challenges around cybersecurity & privacy.
 
Discussions and interactive sessions at the Healthcare Informatics Health IT Summits and Cybersecurity Forums lead to shared learning, exceptional networking and transformative discussions in a unique environment for learning and professional growth.

2018 Conference Chairs
David Kaelber, MD, MPH, PhD Pamela Banchy, CHCIO, RN
Chief Medical Information Officer, Chief Information Officer
Vice President of Health Informatics Western Reserve Hospital
MetroHealth System
Data Days CLE Conference
April 5-6, 2018
Cleveland's Midtown Neighborhood
Please save the date and join the Health Data Matters team and other data- savvy groups in Northeast Ohio for the second annual Data Days CLE conference , April 5th and 6th, being held in Cleveland's Midtown neighborhood. The conference will feature inspirational stories of the use of data and civic tech to solve community problems in Northeast Ohio, opportunities for hands-on training with data sets, analysis, and visualization tools, and Cleveland's first civic tech pitch competition. We look forward to seeing you there!
Research ShowCASE
April 20, 2018
Veale Convocation Center, CWRU
Submit your abstract now! Abstract submission deadline: Sunday, February 18, 2018 (for graduate and professional students, faculty, staff and affiliates).  Undergraduate submissions for Intersections will begin in February.

We invite you to participate with other CWRU faculty, staff and students by presenting your work at Research ShowCASE 2018. The event will provide an opportunity for CWRU researchers to display your research in a traditional scientific poster or other creative means. We encourage University Hospitals, Cleveland Clinic, MetroHealth Medical Center and the Louis Stokes Cleveland VA Medical Center researchers to participate.

In addition to the opportunity to display and share your work, undergraduate and graduate students, professional students and postdoctoral scholars are encouraged to participate in the research competition, which will include having your presentation evaluated and feedback provided. Cash prizes will be awarded to winning entries.

In order to display your work at Research ShowCASE, you will need to submit an online abstract describing your research. If you are a student or post-doc, your faculty adviser will need to approve your submission. Check us out: Like us on FaceBook at  https://www.facebook.com/CWRUResearchShowcase .

ShowCASE is on the web at  http://showcase.case.edu .
National Digitial Inclusion Alliance:
Net Inclusion 2018
April 17-19, 2018
Global Center for Health Innovation & Cleveland Public Library, Cleveland, OH
Thanks to the robust engagement of local advocates, the third annual Net Inclusion Summit will be held in Cleveland. Academics, advocates, policymakers and community members will discuss policy innovations to improve digital equity, and the science around the impact of digital skills and connectivity on many aspects of life. A number of us are planning a pre-conference workshop focused on addressing disparities in use of digital tools for improving health. If you are interested, please contact Amy Sheon.
Translational Science 2018
April 19-21, 2018
Washington, DC
Join AAMC, ACTS, AFMR, and CR Forum at Translational Science 2018, April 19-21 at the Washington Marriott Wardman Park in Washington, DC! 
  • EXPLORE the latest research, including sessions from today's top minds in the field
  • COLLABORATE with more than 1,000 scientific peers during unparalleled opportunities to create new connections
  • EDUCATE yourself on key issues presented by plenary speakers
Injury Control Research Center for Suicide Prevention (ICRC-S)
May 7-11, 2018
University of Rochester, New York
The Injury Control Research Center for Suicide Prevention (ICRC-S)  has announced that its fourth Research Training Institute (RTI) will take place on Monday, May 7th to Friday, May 11th, 2018 at the University of Rochester in Rochester, NY.

The RTI is a five-day series of interactive workshops, presentations, mentoring and small group sessions designed to promote collaboration between suicide prevention researchers and those involved in suicide prevention practice. Faculty include staff from the University of Rochester Medical Center and other experts in the suicide prevention research field. Applicants will be selected through a competitive process that requires researchers and injury prevention/suicide prevention professionals to work as partners to submit one joint application describing a research project which focuses on public health approaches to suicide prevention. 

Application Deadline: January 12, 2018

For more information visit the  ICRC-S website .
Comparative Effectiveness Research:
From All Angles
May 14-15, 2018
CWRU Wood Building, Ground Floor, WG-73
Comparative Effectiveness Research – a core part of Health Care Reform - aims to support the evidence basis for decision making in every part of our health care delivery system. Learn about the methods, and how it impacts health policy, physician practice, health care organizations, and economics of payment. Also, what barriers do we face to acceptance of CER by the general public and legislators? What are the ethical, legal and social issues that are raised, but have yet to be addressed? Is funding support in danger?

Cost-Effectiveness Analysis Crash Course: May 16, 22-23, 9:00 am - 5:00 pm, Wood, WG-73

Take for fun or academic credit (EPBI/MPHP 467)
Visit www.CERCME.wordpress.com or contact Mendel Singer, PhD MPH at

Discounts: Full-time students, interns, residents, fellows, employees of public health depts.
2018 Science of Team Science (SciTS) Conference
May 21-24, 2018
University of Texas Medical Branch, Galveston, TX
Abstract Submission Deadline: March 20, 2018
 
The  SciTS conference  is the annual international forum dedicated to SciTS, bringing together thought leaders from a broad range of disciplines and fields, including: communications, management, social and behavioral sciences, information technology, systems science, and translational research. It provides investigators, academic administrators, and funders with state-of-the-art knowledge, strategies, and connections. SciTS scholars, scientists engaged in team-based research, institutional leaders who promote collaborative research, policymakers, and federal agency representatives will be in attendance. 
 
This year’s conference for the SciTS community will be hosted by the University of Texas Medical Branch in Galveston, Texas on May 21-24, 2018.
 
Workshops
The SciTS Program Committee invites submissions from individuals or groups to conduct  Special Interest Workshops and Seminars .
 
Workshops/Sessions will be 3.5 hours or 6.5 hours in length. All topics relevant to the application of Science of Team Science approaches are welcomed, specifically with respect to training sessions that will equip SciTS investigators with tools and technical skills for data collection, analysis, or presentation in their research areas. Workshop/seminar proposals that incorporate a variety of instructional approaches (e.g. lecture, interactive discussion, hands-on exercises) and materials (e.g. slides, handouts, sample data) are strongly encouraged. We encourage workshops or seminars with a focus on methodologies including systems approaches to the field of SciTS as well as methodologies for conducting evaluation and understanding team dynamics. Furthermore, we welcome workshops and seminars that provide practical guidance for conducting and managing team science in a variety of contexts and settings, and workshops with a focus on developing team science educational and training resources.
 
All workshop submissions should include the information listed in the attached Call for Workshops and should be submitted through our  Workshop Submission Form Acceptance notifications will be made in March 2018, and Workshops will be held between May 21 and 24, 2018.
 
Abstracts
The SciTS Program Committee also welcomes  abstracts  for paper presentations, lightning round presentations, and panel presentations, as well as scientific posters.
 
Paper, Lightning Round, and Poster abstracts are limited to one page, while Panel abstracts are limited to four pages. Abstracts not meeting these page limits will not be considered. A panel proposal must include an abstract summarizing the overall theme of the panel, and panel submissions showcasing research papers should also include individual abstracts for each individual presentation.
 
All abstract submissions should utilize the attached  Abstract Template  and should be submitted through the Abstract Submission Form Acceptance notifications will be made in April 2018. Presenting authors will be responsible for conference registration, travel, and hotel costs. Poster presenters will be responsible for poster printing costs. Abstracts will be compiled and made available to participants.
 
More information about submitting a Workshop proposal or Abstract is attached, and information about conference registration, fees, and additional travel and lodging details will soon be posted on  the conference website .
 
Questions? Contact the conference planning team at  SciTS.2018@utmb.edu.
Cancer Stem Cell Conference
August 6-8, 2018
CWRU Tinkham Veale University Center
Cancer Stem Cell Conference (CSC 2018), hosted by the Case Comprehensive Cancer Center and National Center for Regenerative Medicine, is designed to bring together individuals working in the field of cancer stem cell research. CSC 2018 will feature renowned keynote speakers and leaders in the field. This conference is guaranteed to have cutting edge research from a variety of niches within the field.

CALL FOR ABSTRACTS
Deadline: May 15, 2018 at 5p

The Cancer Stem Cell Conference will feature oral and poster presentations selected from submitted abstracts. All trainees and faculty conducting related research to the topic area are invited to submit abstracts.

To be considered for the Young Investigator Award, abstract submission should also be accompanied by a CV and a letter of support from a current or previous mentor, or colleague. This award is open to senior trainees or junior faculty (less than 5 years from their first independent position).

Visit the   conference website   for more information. 
Funding Opportunities
Thrasher Research Fund
Concept Paper Deadline: March 13, 2018
The  Thrasher Research Fund  provides grants for clinical, hypothesis-driven research that offers substantial promise for meaningful advances in the prevention, diagnosis, and treatment of children's diseases, particularly research that offers broad-based applications.

The fund is inviting concept papers for its Early Career Awards Grants program. Through the program, the fund awards small grants of up to $25,000 to new researchers to help them gain a foothold in the area of pediatric research. The program will consider a variety of research topics important to children's health but will give priority to applicants who show great potential to impact children's health through medical research. Both an applicant's aptitude and inclination toward research will be considered.

The program is open to physicians who are in a residency/fellowship training program or who completed that program no more than one year before the date of submission of the concept paper, as well as postdoctoral researchers who received the doctoral level degree no more than three years prior to the date of submission of the concept paper.

Invited Proposal Deadline: April 27, 2018

For more information visit the  Thrasher Research Fund website .
CWRU VPR Catalyst Awards
Application Deadline: March 30, 2018
The CWRU Vice President for Research and Technology Management is pleased to announce a campus-wide internal grant competition to promote research, scholarship, and creative endeavors.

Intended to foster the incubation of new ideas and their cultivation for production of knowledge, this program will provide faculty the freedom to address new and expanding areas of research, scholarship, and creative endeavor, and will serve as a catalyst for major breakthroughs.

The CWRU VPR Catalyst Awards will be divided into three funding categories:
  1. Research Travel
  2. Publication Subvention
  3. Seed Funds

Eligibility
Principal Investigators/Scholars must hold faculty appointments at CWRU. All full-time CWRU faculty are eligible to apply. Although there is no limit on the number of proposals a faculty member may submit, only one award will be made to any faculty member in a given cycle.

American Diabetes Association
Application Deadline: April 16, 2018
The American Diabetes Association is now accepting applications for the 2018 Core Research Program. The program funds research with novel and innovative hypotheses in any area relevant to the etiology or pathophysiology of diabetes and its complications that hold significant promise for advancing the prevention, cure or treatment of diabetes.

Basic, clinical, translational and epidemiological or health services research approaches are encouraged.

Application Deadline: April 16, 2018

For more informaiton, visit the   ADA webpage.
Children's Leukemia Research Association
Application Deadline: June 30, 2018
The Children's Leukemia Research Association , also known as the National Leukemia Research Association , was founded in 1965 to support research efforts focused on finding the causes of and a cure for Leukemia. To that end, CLRA is seeking applications from investigators for promising research projects in the area of childhood leukemia.

Grants of up to $30,000 will be awarded to promising projects focused on isolating the causes of and finding a cure for childhood leukemia. Funding from other sources is permissible, but CLRA funding objectives should not duplicate those of other sources.

Any doctor at the PhD or MD level involved in research on finding the causes of and/or a cure for leukemia may apply. 

For more information visit the  Children’s Leukemia Research Association website .
HHS, NIH Grant Programs
Following in their long traditions of helping to support important scientific research, the National Institutes of Health and the Department of Health and Human Services have released information on new grant and award programs that we encourage members to take advantage of.

To read more about these award opportunities, check out the  NIH's "Find Funding" website.