Epidemiology and Genomics Research
CANCER EPIDEMIOLOGY MATTERS E-NEWS
MAY 2017

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MAY 2017 Features Announcements
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FOAsFunding
 Opportunity Announcements
PAR-16-348 (R03)
Small Research Grants for Analyses of Data for the Gabriella Miller Kids First Data Resource
Application Due Date: Standard dates apply
Expiration Date: September 8, 2019

PAR-17-269 (X01)
Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access
Application Due Date: Applications are accepted by continuous receipt
Expiration Date: July 11, 2020

PAR-17-273 (U24)
Genomic Community Resources
Application Due Date: The first due date is July 13, 2017; Standard dates apply after that
Expiration Date: January 26, 2020

PA-17-278 (R21)
PA-17-279 (R01)
HIV and Hepatitis B Co-Infection: Advancing HBV Functional Cure through Clinical Research
Application Due Date: Standard AIDS dates apply
Expiration Date: May 8, 2020

PAR-17-217 (R01)
PAR-17-218 (R21)
U.S. Tobacco Control Policies to Reduce Health Disparities
Application Due Date: October 11, 2017; June 13, 2018; October 11, 2018; June 13, 2019; October 11, 2019; June 15, 2020
Expiration Date: June 16, 2020

PA-17-288 (R21)
PA-17-289 (R01)
Leveraging Population-based Cancer Registry Data to Study Health Disparities
Application Due Date:  Standard dates apply
Expiration Date: September 8, 2020
PolicyGrants Policy Announcements
New NIH "FORMS-E" Grant Application Forms and Instructions Coming for Due Dates On or After January 25, 2018
RFIRequests for Information
NOT-OD-17-059
Invitation to Comment on Inclusion in Clinical Research Across the Lifespan
Responses Due: June 30, 2017

NIH Prevention Research Expertise Survey
The NIH Office of Disease Prevention (ODP) is looking for experts in various fields of prevention research to potentially serve as reviewers of NIH research grant applications. This survey, open indefinitely, collects data on scientists' methodological and content expertise, which will be used to support a web-based electronic directory that the NIH Scientific Review Officers can use to identify researchers with expertise in specific prevention science methods and content areas to serve on NIH study sections.
RFPRequests for Proposals
Surveillance, Epidemiology, and End Results (SEER) Program
Proposal Submission Date: July 10, 2017
JobsJob Opportunities
EventsUpcoming Events
June 6, 2017

Webinar: Ethical and Regulatory Issues in Cancer Research - Compensating Research Tissue Donors: Henrietta Lacks and the Ethics of Paying for Biological Specimens
June 8, 2017

Consequential and Reproducible Clinical Research: Charting the Course for Continuous Improvement
June 14-15, 2017
Bethesda, MD

June 21, 2017

International Conference on Ambulatory Monitoring of Physical Activity and Movement
June 21-23, 2017
Bethesda, MD

Webinar: Epidemiology and Perinatal Transmission of Kaposi's Sarcoma-Associated Herpesvirus in Sub-Saharan Africa
June 29, 2017

Webinar: Ethical and Regulatory Issues in Cancer Research - Diverse Patient Values About a 'Library of Medical Information': EHRs and Biospecimens in Research
July 27, 2017

SAVE THE DATE: Understanding the Role of Muscle and Body Composition in Studies of Cancer Risk and Prognosis in Cancer Survivors
September 25-26, 2017
Rockville, MD
  
Webinar: Cancer in Homeless Populations
October 18, 2017

Webinar: Informatics Tools for Analysis of Next Generation Sequencing Studies Supported by the NCI ITCR Program
November 14, 2017

NIH Pathways to Prevention Workshop: Methods for Evaluating Natural Experiments in Obesity
December 5-6, 2017
Bethesda, MD
BlogsBlog Posts
Implementing Limits on Grant Support to Strengthen the Biomedical Research Workforce
Dr. Michael Lauer
Open Mike Blog

Collection of Patient-Reported Outcomes Feasible in Cancer Clinical Trials
NCI Staff
Cancer Currents Blog

Counseling Improves Survivorship Plan Implementation for Low-Income Breast Cancer Survivors
NCI Staff
Cancer Currents Blog
AboutAbout EGRP
The Epidemiology and Genomics Research Program (EGRP) in the Division of Cancer Control and Population Sciences (DCCPS) funds research in human populations to understand the causes of cancer and related outcomes.

The Program fosters interdisciplinary collaborations, as well as the development and use of resources and technologies to advance cancer research and translation of this research, which serve as the basis for clinical and public health interventions.
ContactContact Us
email: nciepimatters@mail.nih.gov
website: epi.grants.cancer.gov
twitter: twitter.com/NCIEpi
PDFSending an Email to an NIH Employee? Read This Important Announcement!


 NIH recently implemented cybersecurity measures that may make it difficult for NIH employees to receive an email if that email has a Microsoft Office document (Word, Excel, PowerPoint) attached.

As a precaution, before emailing any documents to NIH staff, please either convert your documents to a PDF (.pdf) format or disable any active macros on the document. Instructions on disabling macros are available on the Microsoft Office website.

Requesting acknowledgement of receipt is also recommended. If receipt is not acknowledged, consider resending the document in a different format or contacting the recipient by phone. Contact information for all EGRP staff members can be found on the EGRP website: https://epi.grants.cancer.gov/staff/.
 DYK Did You Know logo with blue_ red_ and yellow speech bubbles
Two of the cornerstones of science advancement are rigor in designing and performing scientific research and the ability to reproduce biomedical research findings. The application of rigor ensures robust and unbiased experimental design, methodology, analysis, interpretation, and reporting of results. When a result can be reproduced by multiple scientists, it validates the original results and readiness to progress to the next phase of research.

The National Institutes of Health (NIH) is committed to promoting rigorous and transparent research in all areas of science supported by a variety of grant programs. Updates to application instructions, Research Performance Progress Report (RPPR) instructions, and review language (intended to enhance reproducibility through rigor and transparency) have taken effect. These updates apply to research grants and mentored career development award applications submitted for the January 25, 2016 due date and beyond (see NIH-NOT-OD-16-011).

The updates focus on four key areas. Two of these refer to scored review criteria:
  • The scientific premise of the proposed research
    NIH expects applicants to describe the general strengths and weaknesses of the prior research being cited by the applicant as crucial to support the application.
  • Rigorous experimental design for robust and unbiased results
    Strict application of the scientific method is needed to ensure robust and unbiased experimental design, methodology, analysis, interpretation and reporting of results. This includes full transparency in reporting experimental details so that others may reproduce and extend the findings.
The other two areas are additional review considerations:
  • Consideration of relevant biological variables
    Sex, age, weight, and underlying health conditions are often critical factors affecting health or disease. In particular, there may be potential sex-based differences in basic biological function, disease processes and treatment response. Strong justification from the scientific literature, preliminary data or other relevant considerations must be provided for applications proposing to study only one sex in research of vertebrate animals and humans.
  • Authentication of key biological and/or chemical resources
     include, but are not limited to cell lines, antibodies, specialty chemicals, and other biologics.
Infographic that highlights the four key areas of NIH emphasis on scientific rigor and reproducibility in grant applications. It also includes next steps_ new attachment required_ focus on authentication and validation of key resources_ and standard laboratory reagents that are not expected to vary do not need to be included. Send inquiries to reproducibility_nih.gov or visit www.grants.nih.gov_reproducibility.

To learn more about addressing the four areas described above in grant applications, see the related resource chart. For links to frequently asked questions related to the four areas above, NIH blog posts, examples, and related notices in the NIH Guide to Grants and Contracts related to rigor and reproducibility, visit https://grants.nih.gov/reproducibility/index.htm.

NIH has developed several training modules focused on integral aspects of rigor and reproducibility, including bias, blinding, and exclusion criteria.

Inquiries related to NIH rigor and reproducibility requirements should be sent to reproducibility@nih.gov.
HEI
Introducing the Newest Version of the 
Healthy Eating  Index (HEI)
Healthy Eating Index logo in orange and green
The Healthy Eati ng 
Index (HEI) is  a measure of diet quality that can be used to assess compliance with the U.S. Dietary Guidelines for Americans (DGAs) and determine the quality of a given set of foods. The HEI also is a valuable tool for epidemiologic and economic research and can be used to evaluate nutrition interventions and consumer nutrition education programs.

HEI-2015 is the latest iteration of the index. Staff at NCI and the United States Department of Agriculture (USDA) designed it to align with the 2015-2020 DGAs. As with the previous DGAs, the 2015-2020 edition emphasizes a variety of food groups, nutrient density, and improving food and beverage choices within caloric needs. 

A photograph of fruits_ vegetables_ proteins_ and grains overlaid with connecting dots

Researchers from NCI and USDA unveiled the HEI-2015 at a Symposium during Experimental Biology 2017. Their presentation highlighted new components included in HEI-2015, evaluations of the new version, applications for and research concerns with the tool, and practical tips for using the index. Also, forthcoming manuscripts will include details regarding the development of the HEI-2015, evaluation of the tool, and guidance for researchers using it in their work.

The Epidemiology and Genomics Research Program (EGRP) recently added  information about the HEI and how the metric can be used for research studies   to the EGRP website. This new information includes:
Future HEI web updates (scheduled for summer 2017) will include:
  • Answers to Frequently Asked Questions
  • Information about the basic steps for calculating HEI component and total scores, updated to reflect changes to the HEI-2015
  • Guidance for researchers on interpreting and visualizing HEI scores
  • Tools for researchers using the new version of the index, including an SAS code for HEI-2015
For more information on all versions of the HEI, visit the EGRP website.
Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute | 9609 Medical Center Drive | 4 East, MSC 9763 | Bethesda | MD 20892


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