Read the latest from the membership of NewYorkBIO, including legislative developments, industry and academic research news, and updates on past and future events.
NewYorkBIO News 
November 2015
From the Executive Director

NewYorkBIO kicked off November with the latest program in our "Who Needs a VC 2?" series, a lively forum for analyzing trends in biomedical research funding. Bringing together leaders from foundations, industry, government and, yes, from venture capital, we explored the new models for funding research, including the changing role for biomedical start-ups in partnering with foundations to push promising research into clinical trials and thus into treatments. 
 
Similarly, reading the News from the membership of NewYorkBIO this month, I am struck by some interesting trends in the wide-ranging activities of member organizations: partnering among diverse groups, funding of entrepreneurs and University researchers, and significant findings from the research. 
 
Member groups large and small won international awards since our last News issue; new clinical trials began even as hopeful results from older trials were reported; and there was news from several areas of treatment and research for breast cancer, lymphoma, and schizophrenia.  Members also reported important discoveries that will likely spawn further research: from protein signatures that drive cancers to structures within DNA.
 
Partnering and strategic alliances make another interesting trend in the world of NewYorkBIO this Fall, with member companies, foundations, and research organizations working together on projects.  Chromocell and Astellas made announcements together, as did the Icahn Institute and Regeneron. 
 
Partnership is key to NewYorkBIO members, as our "VC 2" funding forum underscored, and our alliances form the basis of the New York life sciences, just as these relationships impact research and industry worldwide.

And speaking of partnering, I am very proud that NewYorkBIO has partnered with Biotech & Money New York  to bring a great, new event to NYC on November 17. The conference aims to shine a light on New York's life science eco-system, helping promote NYC as a centre for life science excellence. It's where life science meets money, investors meet deal flow and industry promote strategic collaborations. I will be chairing the opening keynote panel, entitled "New York City as a Life Sciences Powerhouse," and sharing the stage with NYC's biosci elite, including Mark Tessier-Lavigne, Tom Maniatis, Judy Dunn, Susan Solomon and many more. I hope to see you there!

Have a Happy Thanksgiving!






Nathan Tinker
Executive Director


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NewYorkBIO invites you to submit a proposal for a panel session at the 2016 Annual Conference Panels are an important component of the Annual Conference, bringing together experts from around the world for an interactive discussion among the panel members and the participants on focused topics.

There are a limited number of panels available and the Annual Conference Committee chooses only those that will enhance the conference program and provide both information and insight for our attendees. 


NewYorkBIO 2016 Annual Conference
May 11-12
10 on the Park  @TIme Warner Center
Columbus Circle NYC

NOVEMBER 17
PolicyPublic Policy & Advocacy

NEW YORK CITY UPDATE
  • On Oct 15, New York City Council Members Daniel Garodnick and Julissa Ferreras-Copeland introduced a bill to continue the NYC Biotechnology Tax Credit for three more years, through December 2018. The credit, originally proposed to the Council by NewYorkBIO in 2008, offers NYC biotech companies up to  $250,000 in a given year for a single company, and $3 million for all companies combined. In 2013, the city awarded $2.4 million through the program to 28 companies, up from 23 companies the previous year. More information
  • A Nov 5 Op-Ed by John Pennett of EisnerAmper, a frequent sponsor of NewYorkBIO events, in Crain's New York encouraged New York City to invest in the sector, saying "Life science start-ups are making tremendous gains in New York City, and our academic and medical institutions, financial community and government should redouble their efforts to create the ecosystem they need. Key participants in every city with a life-science presence are having the same conversation, so there is no time to waste." More information
  • New York City Economic Development Corp president Maria Torres-Springer said on Nov 5 that EDC plans to continue to invest in biotechnology sectorTorres-Springer said the city is nearly ready to break ground on the New York Proton Center in East Harlem and also plans to expand the Alexandria Center for Life Science, to renovate the city's public health laboratory on First Avenue in Manhattan, and to help the New York Stem Cell Foundation finance a new headquarters in midtown Manhattan. An analysis of market trends found demand will reach three million square feet of life sciences space in 10 years, Torres-Springer said. More information

NEW YORK STATE UPDATE
  • NewYorkBIO is leading a coalition to bring smart biosimilars legislation to New York State. As of Oct. 6, 2015, there have been bills or resolutions filed in 31 states related to biologics and/or biosimilars. Of these, 12 (in California, Colorado, Georgia, Illinois, Louisiana, North Carolina, Oregon, Tennessee, Texas, Utah, Washington, and Puerto Rico) have been signed into law in a 2015 session, for a 3-year cumulative total of 17 states and Puerto Rico.  In 2014 eight states enacted the first round of such laws. More information 

FEDERAL UPDATE
  • In an October letter to the FDA, NewYorkBIO joined with the
    Alliance for Safe Biologic Medicines and some 50 other organizations to   encourage the FDA to adopt a policy of  distinguishable names for biosimilars, and to issue final guidance reflecting  distinguishable naming to provide strong patient protections, critical transparency and promote pharmacovigilance. More information
  • In October, NewYorkBIO joined United 4 Innovation in support of repealing the Medical Device Tax. We directly addressed Senator Schumer, asking him to co-sponsorS. 149 - the Medical Device Access and Innovation Protection Act - and vote for legislation repealing the tax. More information
  • In September,  the first U.S. biosimilar drug was launched. AP reported that on Sep. 3, 2015 "Swiss drugmaker Novartis AG launched Zarxio, a biosimilar version of Amgen Inc.'s Neupogen, which boosts white blood cell production to prevent infections in certain cancer and other patients."  Market research firm GBI Research reports at least 150 "copycat" biosimilars are in development this year. More information 

LifeSciNew York Life Sciences Today

Who Needs a VC 2"  Gathers Diverse Funding Experts
On November 4 leaders of research, investment, and company-building gathered at The New York Genome Center on November 4th for NewYorkBIO's "New Models for Funding Biomedical Research." Panelists discussed new models of foundation funding, the critical need for relationships and partnerships in raising capital, and the rise of new capital sources including crowdfunding.

Attendees came from all walks of bioscience life: CFOs mingled with venture philanthropists and start-up founders.Speakers and panelists included representatives from Pfizer, MMRF, the Children's Tumor Foundation, Versant Ventures, the Michael J. Fox Foundation, ELab, EisnerAmper, Cambridge BioLabs, Polliwogg, JDRF, and Nixon Peabody. 

Thank you to Nixon Peabody and EisnerAmper for sponsoring this great event!


Medidata's Bryan Spielman Talks Data to CEOs
The CEO Breakfast Club gathered to hear Medidata CEO Bryan Spielman share his insights into patient data and clinical trial site performance.  The data expert explained that technology is rapidly evolving to collect relevant content more effectively and provide analytics that turn Big Data into actionable intelligence. 

According to Medidata, more and more sponsors are embracing tools that allow them to collect vast amounts of information remotely, such as risk-based monitoring and mHealth technology, and this trend should be used to increase focus on patient care as well as to streamline clinical trials.
  

Events
Upcoming NewYorkBIO Events


Biotech and Money New York
Tuesday, November 17, 2015
7:00 AM - 10:00 PM 
TKP New York Conference Center, New York
Register Here
Wednesday, December 9, 2015
6:00 PM - 9:00 PM 
ConEd Building, 4 Irving Place, NYC
Register Here


Member Spotlight

Allovate Therapeutics is a specialty biopharmaceutical company dedicated to simplifying allergy treatment by providing safe, effective, and convenient new options for allergy sufferers.
 
Oral mucosal immunotherapy (OMIT) is a novel form of allergen-specific immunotherapy. Immunotherapy has a 100-year track record of success for respiratory allergies. OMIT improves upon this approach by delivering immunotherapeutic agents to the areas of the oral cavity with the highest likelihood of prompting a decrease in allergy symptoms in order to improve the health of allergy sufferers.

Clinical investigations led by Allovate are now adapting this technique to the treatment of food allergies. OMIT offers the potential of a long-term solution for the 15 million Americans who have food allergies.

Welcome New Members

Accutar Biotechnology Inc.
 
Adjuvance Technologies Inc
 
Allovate, LLC
 
Berkshire Sterile Manufacturing, Inc.
 
Claymore Technologies, Inc
 
ConSynanceTherapeutics, Inc.
 
Immix Biopharma
 
Immune Pharmaceuticals Corp.
 
Innovimmune Biotherapeutics Holding, LLC
 
Johnson & Johnson Innovation Center
 
Kaneka Americas Holding, Inc.
 
MagnePath USA, Inc.
 
Navitas Pharma, Inc.
 
Optologix, LLC
 
Population Diagnostics Inc.
 
QB Sonic, Inc.
 
S3B Consulting, LLC
 
Saptalis Pharmaceuticals. Inc.
 
Sovereign Laboratories
 
SUMOCOR
 
Superlative BioSciences Corporation
 
Sveikatal, Inc.
 
True Synthesis LLC
 
Ultramend
 
United Biomedical Inc.
 
VentriNova, Inc.
 
Yiviva

NewsNewYorkBIO Member News

NEWS SUBMISSIONS
If you have news to share with other NewYorkBIO members, please send notes or releases to  MV Lamothe, editor

AbbVie
AbbVie announced that IMBRUVICA®  (ibrutinib) was awarded the prestigious Prix Galien 2015 Award for Best Pharmaceutical Agent.
 
Accelerator Corporation
Accelerator Corporation announced the first closing of Accelerator IV with $51.1 million in capital commitments, as it expands its operations in Seattle to New York City. 
 
Actinium Pharmaceuticals
Actinium Pharmaceuticals announced enrollment in the fourth and final cohort in the Phase 1 portion of the ongoing Phase 1/2 trial of Actimab-A has been completed and that enrollment of the maximum tolerated dose (MTD) confirmatory patients is expected to begin in November. 
 
Adjuvance Technologies Inc
Adjuvance Technologies, Inc., announced that the United States Patent and Trademark Office has granted Adjuvance co-founders a patent for a pioneering invention which provides a novel synthetic method to produce saponin adjuvants including QS-21, a leading vaccine adjuvant currently used in advanced clinical trials for infectious disease, neurodegenerative disorders and oncology.

Albert Einstein College of Medicine
Albert Einstein College of Medicine announced receipt of a 3-year, $750,000 grant from the Congressionally Directed Medical Research Programs (CDMRP), an office of the U.S. Department of Defense (DoD). The funding will support research on the mechanism of action of a novel tumor suppressor protein, FILIP1L, which has been shown to inhibit the spread of ovarian cancer. 
 
Astellas  Pharma Inc
Immunomic Therapeutics, Inc., and Astellas Pharma Inc. announced they have entered into an exclusive worldwide license agreement to the LAMP-vax products for the treatment or prevention of any and all allergic diseases in humans.

Bayer Corporation
Bayer submitted a dossier to the World Health Organization Pesticide Evaluation Scheme (WHOPES) for the evaluation of a new two-way insecticide mixture which includes indoor residual spraying (IRS) against disease vectors.

BioMed Realty Trust, Inc.
Blackstone Group LP agreed to buy landlord BioMed Realty Trust Inc. for $4.8 billion, betting on growth in real estate demand from the life sciences and biotechnology industries.

BioSpecifics Technologies Corp.
BioSpecifics Technologies Corp. announced that the first commercial sale of XIAFLEX by Asahi Kasei Pharma Corporation for the treatment of Dupuytren's contracture in Japan has triggered a $1.0 million milestone payment to BioSpecifics.
 
Bristol-Meyers Squibb
Bristol-Myers Squibb announced that the U.S. Food and Drug Administration (FDA) has approved Yervoy (ipilimumab) 10 mg/kg for the adjuvant treatment of patients with cutaneous melanoma with pathologic involvement of regional lymph nodes of more than 1 mm who have undergone complete resection including total lymphadenectomy. 

BlinkBio Inc. (formerly Coferon)
BlinkBio Inc announced that it has entered into a collaboration agreement with Janssen Pharmaceuticals Inc. to accelerate the optimization of prototype leads discovered in the Company's self-assembling dimer program targeting the inhibition of Protein-Protein Interactions.

Chembio Diagnostic Systems, Inc.
Chembio Diagnostics, Inc.,  has been awarded a grant from the Paul G. Allen Ebola Program to develop a POC test to identify multiple life-threatening febrile illnesses.
 
Children's Tumor Foundation
Children's Tumor Foundation 2012 Clinical Research Award winner, Lei Xu, MD, PhD, of Harvard University, will have her research (Anti-VEGF treatment improves neurological function and augments tumor radiation response in NF2 schwannoma model) published PNAS.

Chromocell Corporation
Astellas Pharma Inc. and Chromocell Corporation announced that they have entered into a license and collaboration agreement for the development and commercialization of therapeutics to treat neuropathic and other pain conditions.

Cold Spring Harbor Laboratory
On October 14 th , The Friends of TJ Foundation presented a check for $50,000 to CSHL Associate Professor Chris Vakoc, who is heading the RMS research initiative at Cold Spring Harbor Laboratory as part of CSHL's Sarcoma Research Project.
Read More
 
Columbia Business School
"100 Years of Innovation" celebrates Columbia Business School's Centennial, honoring its innovators, past and present.
 
Columbia College of Physicians and Surgeons
Investigators at Columbia University Medical Center and the Icahn School of Medicine at Mount Sinai have discovered a molecular signaling mechanism that drives a specific type of highly aggressive breast cancer.
 
Columbia Life Science and Technology Ventures, Columbia University
Kartik Chandran, associate professor of earth and environmental engineering at Columbia Engineering, has been named a 2015 MacArthur Fellow for his work in "transforming wastewater from a pollutant requiring disposal to a resource for useful products, such as commodity chemicals, energy sources, and fertilizers."

Conner Strong & Buckelew
Conner Strong & Buckelew, a leading insurance, risk management and employee benefits brokerage and consulting firm, is proud to announce its participation in the National Youth Entrepreneurship  Challenge.

Cornell Medical Center
Weill Cornell researchers have discovered protein signatures on the membranes of small, tumor-secreted packages containing the blueprint that drives cancers to distant organs
 
Covington & Burling LLP
The Hill has named Covington's Holly Fechner and Bill Wichterman to its annual "Top Lobbyists" list.

Eli Lilly & Company
Eli Lilly and Company expands New York City Research and Development site, moving into an additional 30,000 square feet and adding about 50 new jobs in New York.
 
Enumeral Biomedical Corp.
Enumeral announced important progress in its anti-PD-1 antibody program. Enumeral also provided an update on the progress of additional programs in the Company's R&D pipeline, including its TIM-3 and LAG-3 antibody programs.
 
Ernst & Young LLP
EY and LinkedIn announced a new strategic alliance to jointly offer services to help more companies around the world use technology, social networks and innovative sales techniques to empower their go-to-market efforts.
 
Girihlet Inc
Girihlet announced that it is one of 15 biotech start-ups to receive funding ($250k/each) from IndieBio (SOSV).

Harlem Biospace
Harlem Biospace announced applications are open for Spring 2016.
 
Harter, Seacrest & Emery LLP
Harter Secrest & Emery announced that three attorneys have begun practice in the firm's Buffalo office. 
 
HemoGenyx
HemoGenyx has launched a  $200,000 crowdfunding campaign  to fund pre-clinical studies and support the filing of an Investigational New Drug application with the U.S. Food and Drug Administration.
Read More
 
HHMI /The Rockefeller University
The Royal Swedish Academy of Sciences announced that Paul Modrich, a Howard Hughes Medical Institute (HHMI) investigator at Duke University, Tomas Lindahl of the Francis Crick Institute and Clare Hall Laboratory in the UK, and Aziz Sancar of University of North Carolina, Chapel Hill, are the recipients of the 2015 Nobel Prize in Chemistry for mechanistic studies of DNA repair.
 
Immune Pharmaceuticals Corp.
Immune Pharma Submits IND in the U.S. for its Lead Product Candidate Bertilimumab for the Treatment of Bullous Pemphigoid.

Intensity Therapeutics, Inc.
The Board of Kuala Innovations Limited  announced that it has subscribed for a 3.5 per cent. interest in Delaware incorporated private company Intensity Therapeutics, Inc. 
Read More
 
International AIDS Vaccine Initiative
The non-profit International AIDS Vaccine Initiative (IAVI) and biopharmaceutical company CureVac are partnering to accelerate the development of AIDS vaccines, utilizing novel immunogens developed by IAVI and partners, delivered via CureVac's novel messenger RNA (mRNA) technology.
 
Intra-Cellular Therapies, Inc
Intra-Cellular Therapies, Inc.,  announced positive results from the first Phase 3 clinical trial of ITI-007 for the treatment of patients with schizophrenia. 

IRX Therapeutics, Inc
PCT, LLC announced that it will expand its current manufacturing capacity at PCT's Allendale, New Jersey, facility to support IRX Therapeutics's anticipated clinical trial manufacturing needs for the INSPIRE Phase 2b study in head and neck cancer patients. 

Medidata Solutions
INC Research Holdings, Inc., and Medidata announced that INC Research has been named the recipient of Medidata's Trial of the Future Award in the Operational Excellence category. 
 
MetaStat, Inc.
MetaStat announced reverse stock split in preparation for a proposed uplisting to a national market.
 
Mintz Levin
Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. added to its Intellectual Property team in Washington, D.C. with Mark Pino, a leading attorney in the pharmaceutical, biotechnology, and chemical areas

Moses & Singer LLP
Moses & Singer announced that a total of 41 attorneys were chosen for distinction in the 2015 Metro Edition of New York Super Lawyers®. 

New York Blood Center, Inc
New York Blood Center (NYBC) and the Howard and Abby Milstein Foundation announced a further expansion of their collaborative efforts to advance the use of specialized stem cell lines in regenerative medicine.
 
New York City College of Technology
City Tech congratulates Professor Robert Russo, chair of the Department of Vision Care Technology, who received the National Academy of Opticianry "Joseph Bruneni Memorial Education Achievement Award."
 
New York Genome Center
The New York Genome Center announced that it was awarded a National Heart, Lung and Blood Institute Whole Genome Sequencing and Omics Project for the Trans-Omics for Precision Medicine Program contract of $13.5 million dollars for large-scale whole genome sequencing.

The New York Stem Cell Foundation
The New York Stem Cell Foundation (NYSCF) announced the 2015 class of NYSCF - Robertson Investigators, selecting five of the most talented scientists.  Each Investigator will receive a $1.5 million award, disbursed over the next five years.
 
New York University Langone Medical Center
New studies by researchers at NYU Langone Medical Center show that insulin plays a much stronger role than previously known in regulating release of dopamine, a neurotransmitter that helps control the brain's reward and pleasure centers.
 
New York Presbyterian Hospital
Early data from a NewYork-Presbyterian/Columbia pilot study suggests that an innovative microsurgery technique helps prevent lymphedema in breast cancer patients. Results from the study have been published in the Annals of Surgical Oncology.

Novomer LLC
Novomer announced that Jowat AG is the first to commercially adopt Novomer's new Converge® polypropylene carbonate (PPC) polyols for use in polyurethane hot melt adhesive applications.

Ophthotech Corporation
Ophthotech Corporation  announced the completion of patient recruitment for its second Phase 3 trial of Fovista® (pegpleranib) in combination with Lucentis® (ranibizumab) for the treatment of wet age-related macular degeneration (AMD).
 
Optologix LLC
Dr. Gardner, CSO of Optologix, is featured in an interview by  ASBMB Today .

Pfizer, Inc.
Pfizer Inc. announced the completion of an agreement with Protalix in which Pfizer will expand its support of ELELYSOTM (taliglucerase alfa) for the Gaucher community. 
Read More
 
PricewaterhouseCoopers LLP
PwC US announced the appointment of David Ethridge to Managing Director in the firm's Deals practice and U.S. IPO Services leader.
 
Progenics Pharmaceuticals Inc.
Valeant Pharmaceuticals International , Inc., and  Progenics Pharmaceuticals, Inc.,  announced that the  U.S. Food and Drug Administration  (FDA) has accepted for review Valeant's New Drug Application for RELISTOR® (methylnaltrexone bromide) Tablets.
 
Prophylix Pharma
Prophylix Pharma will take its novel prophylactic NAITgam intoPhase I/II trials in Q3 2015. NAITgam protects newborns against therare but potentially crippling and fatal bleeding disorder calledFetal and Neonatal Alloimmune Thrombocytopenia (FNAIT). 
 
Provista Diagnostics Inc.
Provista Diagnostics, Inc., announced the reelection of the company's Board of Directors. 

PsychoGenics Inc.
PGI Drug Discovery LLC (PsychoGenics) announced that the Company has extended its drug discovery and development collaboration with Sunovion Pharmaceuticals, Inc., for another four years. 

Purdue Pharma, L.P.
Purdue Pharma L.P. and AnaBios Corporation announced the intent to form a joint venture aimed at accelerating the development of Purdue Pharma's Nav1.7 sodium ion channel compounds for the treatment of chronic pain. The joint research and development effort would leverage Purdue Pharma's intellectual property and lead compounds, combined with AnaBios' Phase-X® technology.

Regeneron Pharmaceuticals Inc.
Icahn School of Medicine at Mount Sinai and Regeneron announce new antibody research agreement.

The Research Foundation of SUNY
An enigmatic RNA gene is being studied by a University at Albany Cancer Research Center post-doctoral associate, Rebecca Sinnott DeVaux, as a tool to distinguish aggressive from indolent breast cancers and identify why some breast cancers become life-threatening metastasis.
 
The Rockefeller University
A team of researchers from The Rockefeller University, Brookhaven National Laboratory, and Stony Brook University has revealed the molecular architecture of the DNA replisome.
 
Signal Genetics, Inc.
Signal Genetics, Inc. , announced the signing of additional preferred provider organization (PPO) agreements.
 
Slone Partners
Slone Partners announced the placement of Dr. Richard Bender as Chief Medical Officer at Signal Genetics, Inc., a commercial stage, molecular genetics diagnostic company. 

SUNY Downstate Medical Center
The State University of New York announced $530,000 in funding for two collaborative research projects involving SUNY Downstate Medical Center, the University at Buffalo, and Stony Brook University that will advance understanding of the human brain as part of the SUNY Brain Network of Excellence.

University of Albany, SUNY
University at Albany President Robert J. Jones joined Senator Chuck Schumer (D-NY) and Blackstone Charitable Foundation President and Chief Operating Officer Tony James in New York City to announce the expansion of the Blackstone LaunchPad entrepreneurship program to the University and four New York State universities.
 
University of Rochester
The Center for Emerging and Innovative Sciences (CEIS) at the University of Rochester has been renewed by New York State as one of its Centers for Advanced Technology (CAT) and will receive $9.2 million in funding over the next 10 years.

Weill Cornell Medical College
A new therapeutic approach that targets an aggressive form of lymphoma may greatly increase the efficacy of treatment and result in better outcomes for patients, according to new research by scientists at Weill Cornell Medicine.
 
White & Case
White & Case LLP and Mergermarket released a new report, "The Cutting Edge: Shaping the Future of Digital Healthcare," which surveyed US-based senior-level executives in the life sciences and technology fields about their views of the future of digital healthcare and the obstacles they may need to overcome to successfully develop digital healthcare products and services.
 
Willis HRH
Willis Group Holdings plc  announced the completion of its acquisition of  PMI Health Group , a leading independent healthcare adviser and broker in the  UK .
 
WISE
WISE has received the 'BtoB Award 2015' (start up section), organized by Hubnet. 

MV Lamothe, Editor | NewYorkBIO | (212) 433-2623 | [email protected] | NewYorkBIO.org
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