The CCTS Investigator
Accelerating Discoveries Toward Better Health
October 2017
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The OSU CCTS facilitates and supports translation of scientific discoveries into innovations that improve health. To achieve this mission and advance translational research, the CCTS is expanding its offering of voucher awards to provide funding support to investigators who require assistance from an Ohio State University or Nationwide Children’s Hospital core service to enable preliminary work and generate data for new or ongoing projects and/or to secure fee-based core services for expert consultation services (such as biostatistics) with the ultimate goal of furthering clinical and translational research.
The new voucher core additions include:
- Campus Chemical Instrument Center and Imaging Facility
- Campus Microscopy and Imaging Facility
- Multiscale Mechanical Characterization of Materials
- Behavioral Measurement Shared Resources (BMSR)
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The following faculty and fellows from Nationwide Children's Hospital and OSU were awarded intramural funding grants in 2017.
These projects are typically conducted over a period of two years. Upon completion, each award recipient is required to present his/her findings at a Clinical and Translational lunch seminar held quarterly at Nationwide Children's.
August 2017 Recipients:
Elaise Hill, MD
(Fellow, Emergency Medicine):
"Novel Urine Biomarkers to Distinguish UTI from Culture-Negative Pyuria"
Margaret Redmond, MD
(Faculty, Allergy/Immunology):
"Managing Anaphylaxis in the Pre-Hospital Setting"
Jordee Wells, MD
(Fellow, Emergency Medicine):
"Effect of Emergency Contraception Legislation on Teen Pregnancy Rates"
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Three OSU CCTS longitudinal pilot (L-Pilot) cross-campus teams advance with new awards
.
The CCTS Longitudinal (L-Pilot) program
was inaugurated in 2014 to incentivize the long-term development of promising interdisciplinary projects towards major success stories (i.e. significant extramural programmatic funding and/or commercialization).
Here are the most recent CCTS L-pilot awards for Phase 2 and Phase 3 studies:
2017 L-Pilot Phase 2 Award:
Improving Efficacy of Anti-Leishmania Vaccine using a Novel Adjuvant Pentalinonsterol
TEAM PI: Abhay Satoskar, MBBS, MD, PhD
, Professor, College of Medicine and College of Arts & Sciences
- College of Medicine: Bradford McGwire MD, PhD & Narasimham Parinandi, PhD
- College of Pharmacy: James Fuchs, PhD & Doug Kinghorn, PhD
- College of Veterinary Medicine: Ryan Jennings, DVM, PhD
- Center for Biostatistics: Xiaoli Zhang, PhD
2017 L-Pilot Phase 3 Awards:
Disposable Electroceutical Dressings to Treat Chronic Wound Biofilm Infection
TEAM PI: Sashwati Roy, PhD,
Professor, College of Medicine
- College of Engineering: Vish Subramaniam, PhD & Shaurya Prakash, PhD
- College of Medicine: Gayle Gordillo, MD; Dan Wozniak, PhD & Hamdy El-Sayed Awad, MD
- College of Nursing: Jodi McDaniel, PhD
- Departments of Biomedical Informatics and Center for Biostatistics: Guy Brock, PhD
- Nationwide Children’s Hospital: Chris Shilling, MS, Drug & Device Development
A Systems Biology approach to advance the understanding and treatment of Patients with Chronic Granulomatous Diseases using a Novel Ex Vivo Human Model
TEAM PI: Elliott Crouser, MD,
Professor, College of Medicine
- College of Medicine: Wolfgang Sadee, PhD & Peter White, PhD
- College of Arts and Sciences: Avner Friedman, PhD
- Consultant: Larry Schlesinger, MD, President & CEO, Texas Biomedical Research Institute
- Mentees: Van Le, MD; Landon Locke, PhD & John Frater (MD/PhD)
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Monday, November 13, 2017, 1-2pm
B040 James Cancer Hospital
Starting your own laboratory research program from scratch can be daunting, but there are ways to maximize your chance of success.
Drs. Ronny Freud, Jose Otero, and Mandy Toland will highlight some of the strategies used to quickly and effectively set up your new laboratory and move forward with productive res
earch projects.
Registration ends Nov. 12. at 1:00pm.
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Monday, December 4, 2017, 12-1pm
L035 James Cancer Hospital
Faculty profiles share the personal and professional stories of senior faculty members as an opportunity for other faculty members to glean insights and make connections. Michael Caligiuri, MD is CEO of the James Cancer Hospital and Solove Research Institute and John L. Marakas Nationwide Insurance Enterprise Foundation Chair in Cancer Research. Lunch Provided
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Save the Date: Intramural Funding Program Deadlin
e
Dec. 1
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Intramural grants are available to physicians, psychologists and other clinical staff at
Nationwide Children's Hospital
if they also hold a faculty appointment at The Ohio State University. Residents and fellows also may apply. Research Institute faculty are eligible to apply if a collaboration with a Nationwide Children's clinician is proposed.
For more information on the Intramural Funding Program, please visit the
ANCHOR website
(Nationwide Children's Hospital intranet/campus access only).
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Registration is now open for the next OSU CCTS Tools of the Trade workshop.
The Center for Clinical & Translational Science is offering a program on Innovation and Entrepreneurship in Biomedicine. At this program you will learn a practical technique to identify unmet needs that could be answered by your innovative idea. You will also learn about intellectual property issues, find out how the Technology Commercialization Office can help you, and meet physician scientists who have created innovative healthcare products.
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Heal Ohio is a statewide collaborative that aims to unite scientists, healthcare professionals, and commercial partners who share a common vision and mission to solve problems associated with wound care. In doing this, it will serve to bridge the gaps that exist between clinics, research, business, and patients. The conference is scheduled for Nov. 2.
The 2017 speaker line-up features a variety of topics and sessions, including a presentation by Dr. Sashwati Roy, a CCTS L-pilot awardee.
The
2017 Heal Ohio Conference
will be devoted to health professional presentations and feature informative learning sessions and keynote addresses. Activities are expected to provide an atmosphere rich in collaboration and networking for both career and research advancement. This event is approved for 9 CME credits.
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Designated as a Carnegie community-engaged institution, Ohio State is reaffirming its land-grant covenant with the people of Ohio, the nation and the world through meaningful partnerships that make a measurable impact on resolving the issues of our time. By doing so, we increase our relevance, and consequently, our value to our communities. We believe the most effective partnerships are based on a spirit of reciprocity and mutual benefit where the contributions of both partners are valued and celebrated.
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The overall goal of the CCTS TL1 program is to provide trainees with the skills required to develop a career in trans-disciplinary clinical and translational research relevant to human health.
The TL1 award is available to:
- Students pursuing a PhD with training and research focused on clinical or translational science;
- Post-professional degree students enrolled in resident or fellow education programs and who do not hold faculty appointments at the level of assistant professor or higher pursuing a degree in clinical or translational science; and
- Pre-professional degree students pursuing training in health professions (e.g. MD, DDS, DVM, Pharmacy, Clinical Psychology, and other professional degree programs)
All TL1 awardees will receive:
- Stipend support awarded at the NIH allowed annual maximum;
- Tuition support;
- Limited funding to defray the cost of the research program and travel to national meetings;
- Access to the CCTS professional services and staff including biostatistics, subject recruitment, and human subjects approval; and
- Access to a training curriculum in clinical and translational research methodology and specialized seminars.
The OSU CCTS is currently accepting applications for the 2017 TL1 Program.
View the RFA here
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Did you know?
REDCap
has a Shared Library!
The
REDCap Shared Library
is a repository with over 1665 REDCap data collection instruments/forms that is continuously growing.
The instruments/forms can be downloaded and used by All REDCap Users. To access the Shared Library, select project setup / Online Designer / Import Redcap Shared Library.
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NCATS encourages applications in drug discovery and development; biomedical, clinical and health research informatics; clinical, dissemination and implementation research; and clinical trials. Start the application process now to ensure a smooth submission.
The next deadline to apply for opportunities is Jan. 5, 2018, 5:00 p.m. local time.
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This funding opportunity announcement (FOA) seeks to develop and nurture a national innovation ecosystem that builds upon biomedical research to develop technologies, products, and services that benefit society. Toward meeting this objective, the I-Corps™ program is being offered. The I-Corps™ at NIH program is focused on educating researchers and technologists on how to translate technologies from the lab into the marketplace. Under this FOA, participating NIH and CDC Institutes and Centers will continue providing administrative supplement awards to currently-funded SBIR and STTR Phase I grantees.
Due December 18, 2017.
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This Funding Opportunity Announcement invites applications for support of clinical studies to repurpose existing drugs or biologics (therapeutics) that have already completed at least a Phase l trial for a different indication by the time an award is made. The hypothesis for proposed studies must be developed using innovative processes to identify the therapeutic/indication pair.
The U01 award may be used for Phase I and/or Phase II clinical trials for a new therapeutic use to establish substantial evidence of efficacy and to establish evidence of safety for the new use.
Due January 5, 2018.
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Funding Opportunities from the NIH.
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Deadline: November 13, 2017
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Deadline: December 1, 2017
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Read about the latest translational science news, opportunities, and announcements in the latest edition of the NCATS e-Newsletter and the NIH's Weekly Funding Notice.
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Learn more about PCORI through their blog, video room, news releases, and other resources.
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Discover the latest news in translational science and grant opportunities from the Association for Clinical and Translational Science's monthly newsletter.
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When you sign up as a member of the OSU CCTS, you are entitled to become a member of
The Association for Clinical and Translational Science
at no cost
.
As a member of the ACTS, you have access to a wide variety of benefits and tools to assist you with your research. These benefits include:
- Discounted registration for the Translational Science Meeting
- Email updates and web access to relevant translational science topics
- Access to the ACTS newsletter, the ACTS Connection
- Access to articles in the Journal of Clinical and Translational Science, published by Cambridge University Press
- Opportunities for development and participation in committees and special interest groups
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Tools of the Trade: Innovation and Entrepreneurship in Biomedicine
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