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MCH's 49th Annual Pediatric Postgraduate Course
February 27- March 2
2014
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Severe Kingella kingae Osteoarticular infections in children.
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While K. kingae osteoarticular infections in children are frequently clinically mild, a retrospective study of a small series of 10 children (mean age 21 months) who presented with severe osteoarticular infections caused by this organism reminds us that severe bone disease can present without fever or elevated C-reactive protein levels. Delay in diagnosis may result in bony lytic lesions and growth cartilage damage.
Pediatric Infectious Disease Journal |
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Updates in Pediatrics Primary Readership Study February 2014
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Probiotic effects on late-set sepsis in very preterm infants
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While probiotic use appears to reduce mortality and necrotizing enterocolitis (NEC) in preterm infants, their effect on late-onset sepsis is unclear.
A randomized control study of a probiotic combination or a placebo given daily (in 1099 mostly breast milk fed very preterm infants), examined the differences found , with & without their use, for late-onset sepsis, NEC and mortality.
Probiotic administration appears to reduce the risk of NEC in preterm infants - it does not appear to reduce late-onset sepsis or mortality. Pediatrics |
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