January 15, 2014   Vol. V, Issue 3
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The long-term effects of maternal depression.  

Maternal depression during pregnancy and early childhood predicts worse physical health during childhood, with increased health related stress, increased levels of depressive symptoms and poor social functioning at age 20 years.

Propranolol vs prednisolone vs propranolol plus prednisolone treatment for infantile hemangiomas.

A prospective randomized study of 30 children (aged 1 week to 8 months) with infantile hemangiomas treated with oral propranolol (2-3mg/kg/day) prednisolone (1-4mg/kg/day) or both for at least three months, indicates that propranolol alone has a consistently rapid therapeutic effect ( compared to prednisolone & which has more complications), with the combination of therapies not improving efficacy.


Journal of Pediatric Surgery 

 Impact of new 16 hour restriction of duty on pediatric interns' neonatal education.

With the institution of the <16 hour duty restriction, neonatal residents apparently attend fewer didactic lectures, grand rounds and mock resuscitations. However, no differences in other measured parameters or test score affecting clinical experience or knowledge are evident.


Clinical Pediatrics
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Early lexical (number of words) development, language comprehension & nonverbal intelligence at school age.  


A large study of 2,724 Dutch children evaluated communication at 1-5 years and language development at 2.5 yrs. relating them to vocabulary comprehension and non-verbal intelligence at 6 years of age.  


Demographic factors (male gender, low maternal education, and non-Western ethnic background) primarily predict delays in language and non-verbal abilities as children enter school. Early (<2 years) onset word acquisition does not predict later language comprehension, however later vocabulary attainment appears to increase the risk of language comprehension delay and poorer non-verbal intelligence at 6 years of age.


Acta Paediatrica 

Food additives & preservatives on the behavior of young children.


The addition of artificial colorings (AFC's) and preservatives to foods consumed by young (mean age 8.6 years) children has been suggested to affect their behavior. A within-subject crossover study of 130 boys and girls in Hong Kong compared behavior scores with and without exposure to AFC's plus a preservative. No significant association between additives/preservatives and behavior appears to exist.


Journal of Developmental and Behavioral Pediatrics

Video Feature  
Is Red Food Dye #40 driving your child crazy?
Is Red Food Dye #40 driving your child crazy?
via YouTube

Clinical characteristics of severe supracondylar humerus fractures in children.


Supracondylar humerus fractures are one of the more common fractures that occur in children and are frequently associated with the development of serious complications. They may be of a flexion or extension type, depending on the displacement of the distal fragment. Usually they are classified as types 1, 2, 3 and 4 (modified Gartland classification); with type 3 fractures being completely displaced.  


A retrospective study of the clinical, emergency, operatively treated inpatient and outpatient records of 872 children with type 3 fractures, was utilized to identified "time to surgery" (6-12 hours; 12-24 hours; >24 hours) to compare it to morbidity from the injury or treatment.  


Increased "time to surgery" following a severe supracondylar humerus fractures is not associated with an increased complication rate and can be treated safely in a delayed manner.


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