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Dear Friends,
Each year our premier event, Symphony at Salk, blends science and art to inspire creativity and enrich our understanding of the world.
This year’s concert on August 19 will feature GRAMMY Award winner Jennifer Hudson and the always outstanding San Diego Symphony. The unique experience will also include a champagne reception and gourmet dinner set in Salk’s iconic Courtyard overlooking the Pacific Ocean.
I am looking forward to the exciting entertainment and the opportunity to showcase our world-class Institute, and I hope many new supporters and community members will join us for an unforgettable evening.
Sponsorship and ticket details can be found at salk.edu/Symphony. If you have any questions, please feel free to reach out to us at communications@salk.edu.
Warmest regards,
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Gerald Joyce
Salk Institute President
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Why we lose fat and muscle during infection | Although infections can present with many different symptoms, one common symptom is the loss of fat and muscle, a process called wasting. Professor Janelle Ayres and team discovered the wasting response to T. brucei infection in mice occurs in two phases, each regulated by different immune cells. While fat loss did not benefit the fight against infection, muscle loss did—a surprising clue that some wasting may help manage illness. The findings can inform the development of more effective therapeutics that spare people from wasting and increase our understanding of how wasting influences survival and morbidity across infections, cancers, and chronic illnesses, and more. | | | |
Revealing HIV drug-resistance mechanisms through protein structures | | |
 
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Associate Professor Dmitry Lyumkis and team, in collaboration with the National Institutes of Health, discovered the molecular mechanisms by which the human immunodeficiency virus (HIV) becomes resistant to Dolutegravir, one of the most effective, clinically used antiviral drugs for treating HIV. The new study reveals how changes to the 3D structures of integrase, an HIV protein, can lead to Dolutegravir resistance and how other compounds may be able to overcome this resistance. Read more »
See also:
Genetic Engineering & Biotechnology News »
Drug Target Review »
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Preying on hungry, anxious worms | | |
 
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The life of the tiny worm called C. elegans consists mostly of looking for food, eating food, and laying eggs. So, when any of these behaviors are disrupted, there’s cause for concern. In a new study, Professor Sreekanth Chalasani and team discovered that the “feel good” brain chemical dopamine regulates anxious worm behavior in the presence of nipping predators. The findings illuminate how this dopamine-regulated brain pathway may be related to anxiety and could provide insight into human conditions, such as post-traumatic stress disorder (PTSD).
Read more »
See also:
Medical Xpress »
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San Diego Pride hosted a week-long celebration to foster pride, equality, and respect for lesbian, gay, bisexual, and transgender communities. The Salk Institute handed out Salk Pride Society pins, pride, and science stickers, and thematic rainbow science pamphlets during the festival on July 15 and 16 in Balboa Park. | | | |
Korean Ministry of Health visit | On July 5, President Gerald Joyce met with the Korean Ministry of Health for a discussion of Salk research, followed by a tour of the Institute. | |
Salk employees, interns, contractors, and families enjoyed an afternoon of food, games, activities, and fun in the sun on July 21. The annual event had a record turnout and featured volleyball, corn hole, and table tennis tournaments. | |
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Forbes
Farms of the future will grow food while restoring the environment: Here’s how
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Features Professor Joanne Chory
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Axios
AI tools trace the body’s link between the brain and behavior
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Features Salk Fellow Talmo Pereira
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Medium
Are AIs actually intelligent?
Read article »
Features Professor Terrence Sejnowski
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Genetic Engineering & Biotechnology News
A vaccination strategy against diarrhea-causing pathogens
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Read article »
Features Professor Janelle Ayres
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V Foundation for Cancer Research grant awardee | Assistant Professor Christina Towers has received the A Grant of Her Own: The Women Scientists Innovation Award for Cancer Research. Towers will receive $600,000 over three years as a part of her V Scholar Award to fund her work uncovering novel metabolic susceptibilities in pancreatic cancer. The V Foundation awards competitive grants to the top cancer researchers in the country. | | | |
Salk Institute mourns the loss of former Board trustee, longtime supporter Margaret Faye Wilson | | |
 
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Margaret Faye Wilson, a leader in the banking and retail industries, died on July 10. She served as a Trustee on Salk’s Board from 2010 to 2019 and was a generous donor of the Institute over the years, including supporting the Institute’s premier annual event, Symphony at Salk. Read more » | | |
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Your support powers groundbreaking research, and the people who bring it to life. | |
Enjoy Salk architecture on your devices | |
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Looking for a unique background image for your computer, Zoom meeting, iPad, or phone?
Louis Kahn, esteemed architect of Salk, used a “pozzolanic” concrete to construct the Institute. First formulated by the ancient Romans, the volcanic pumice aggregate and cement mixture gives the concrete water resistance and a warm, pinkish hue.
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About this newsletter
Salk’s email newsletter is published monthly with updates on recent scientific publications, media coverage, awards, grants, events, and other timely information for Salk supporters and science enthusiasts.
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