MARCH 2023 NEWS
Wearable microscopes advance spinal cord imaging in mice
Associate Professor Axel Nimmerjahn and team have created wearable microscopes that enable unprecedented insight into the signaling patterns within the spinal cords of mice. The lab’s technological advancement will help researchers better understand the neural basis of sensations and movement in healthy and diseased contexts, such as chronic pain, itch, amyotrophic lateral sclerosis (ALS), or multiple sclerosis (MS).
New combination of drugs works together to reduce lung tumors in mice
Standard chemotherapy and immunotherapy treatments are not effective for the roughly 20 percent of non-small cell lung cancer (NSCLC) cases that have an LKB1 genetic mutation. A new study led by Professor Reuben Shaw and team revealed that two drugs, one FDA-approved and one in clinical trials, can be given in tandem to produce fewer and smaller tumors in mice with LKB1-mutated NSCLC. This discovery could be transformative for cancers beyond NSCLC, with potential applications in lymphoma, melanoma, and pancreatic cancer. Read more »

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AI chatbot ChatGPT mirrors its users to appear intelligent
In a recent paper, Professor Terrence Sejnowski explored the relationship between the human interviewer and chatbot to uncover why chatbots respond in particular ways, why those responses vary, and how to improve them in the future. According to Sejnowski, chatbots mirror their interviewers, similar to the Mirror of Erised in the first Harry Potter book, which reflects desires, rather than truths, back to the user. Read more »

See also:
EVENTS
MAY
25
4:30 p.m.
Science & Justice Series

Join us for the launch of the Salk Science & Justice series. During this inaugural event, Professor Thomas Albright will join Peter Neufeld, civil rights lawyer and cofounder of The Innocence Project, to discuss the latest research on visual perception and memory, how that influences forensic identification decisions, and what that means for justice in our criminal legal system. Members of the public and individuals involved professionally in criminal law, scientific research, public policy, and social justice, who follow and/or await developments in this realm, will have a unique opportunity to learn more about the intersection and contradictions between science and law during this event.

Recapping March 7: International Women’s Day
International Women’s Day celebrates the achievements women have had socially, economically, culturally, and politically in our world and challenges us all to embrace equity and broaden and deepen the impact of women. In honor of this day, Salk’s Diversity, Equity & Inclusion team along with Salk Women & Science hosted an Accelerating Women’s Path to Impact networking event, which focused on building and leveraging dynamic networks to fuel and bolster career development.
Recapping March 18: Padres Pedal the Cause
Padres Pedal the Cause is an annual event with participants biking, running, walking, and spinning to support cancer research. Since 2013, the event has raised $20 million and funded 73 collaborative research projects in San Diego, including six clinical trials. Team Salk Cancer Center supported the effort to raise money for local cancer research, which includes projects on Salk’s campus. Learn more about the event »
Recapping March 26: Lustgarten Foundation Walk for Research
On the last Sunday of March, the Lustgarten Foundation hosted its Walk for Research, a short 1K stroll around the Salk Institute followed by conversation with Salk researchers. The Lustgarten Foundation works to raise the critical funds and awareness needed to transform pancreatic cancer into a curable disease. Learn more about the event »
IN THE NEWS
Google Cloud

Salk Institute leverages Google Cloud for brain research—and launches its transformation to the cloud


Features Associate Professor Eiman Azim and Professors Joseph Ecker, Gerald Joyce, and Joanne Chory
Huberman Lab Podcast

Dr. Satchin Panda: Intermittent fasting to improve health, cognition & longevity


Features Professor Satchidananda Panda
Fox 5

How the time change affects our bodies


Features Professor Satchidananda Panda
KPBS

Salk Institute’s new president to tackle ‘endless frontier’ of science


Features Professor and President-Designate Gerald Joyce
Spectrum News 1

New discovery gives hope that someday Alzheimer's disease might have a cure


Features Professor Rusty Gage and Graduate Student Joseph Herdy
MSN

Could stimulating the happiness molecule cure depression?


Features Professor Kay Tye
SPOTLIGHT
2023 Innovation and Collaboration Grants
From left: Jesse Dixon, Dannielle Engle, Julie Law, Christian Metallo, and Talmo Pereira.

Professor Christian Metallo, Assistant Professor Dannielle Engle, and Salk Fellow Talmo Pereira will build AI-based models to relate changes in mouse behavior and diet to pancreatic cancer progression and whole-body physiology. Their findings will further AI application in cancer treatment while improving our scientific understanding of diet and chemotherapy, which are key factors important to all cancer patients.

To better understand the connections among chromatin modifications, genome organization, and gene regulation in plants, Associate Professor Julie Law and Assistant Professor Jesse Dixon will use a genomic analysis technique called Hi-C to explore how genetically altered chromatin states impact genome organization.
PlantACT! Public Panel Recording
In case you missed it, Salk Professors Joanne Chory and Wolfgang Busch took part in a PlantACT! event in New York City in early March. PlantACT! is a European initiative, founded to unite plant science experts in the fight against climate change. A recording of the event is now available for those who couldn’t attend in person—watch now to hear plant scientists describe sustainability solutions, climate mitigation tactics, and how you can get involved.
Your support powers groundbreaking research, and the people who bring it to life.
SCIENCE QUIZ
This month, Professor Terrence Sejnowski made major contributions to the conversation surrounding artificial intelligence and large language models, like ChatGPT. After being made publicly available for use in November 2022, ChatGPT quickly became a household name.
Now, in 2023, about how many individuals use ChatGPT daily?
3 million
8 million
13 million
20 million
Last month's science quiz results

Last month, Salk scientists discovered a new link between mitochondria and telomeres that advances our understanding of cancer and aging. With their work, we may be able to create therapies for preventing or mitigating the negative effects of aging.

In what country do people, on average, live the longest?
Answer: Monaco! On average, both men and women live about 87.01 years in Monaco. Hong Kong comes in second, at 85.83 years, followed by Macau, at 85.51 years.
Enjoy Salk architecture on your devices
Looking for a unique background image for your computer, Zoom meeting, iPad, or phone?

March 20 was the spring equinox, marking the first day of spring. Salk employee Edwin Llacuna captured this photo of the sun aligned with campus’ iconic “River of Life,” which was designed so that, on spring and fall equinoxes, the sun would set along its axis—a phenomena known as “Salkhenge.”
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Salk’s email newsletter is published monthly with updates on recent scientific publications, media coverage, awards, grants, events, and other timely information for Salk supporters and science enthusiasts.
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