Time-restricted eating reshapes gene expression throughout the body |
Professor Satchidananda Panda and team discovered that time-restricted eating influences gene expression in 22 regions of the bodies and brains of mice. The findings have implications for a wide range of health conditions in which time-restricted eating has shown potential benefits, including diabetes, heart disease, hypertension, and cancer.
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Microprotein increases appetite in mice |
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Credit: Salk Institute and Cell Metabolism
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Professor Alan Saghatelian and team found a microprotein that can increase appetite in mice. The findings could lead to the development of a therapy to help people gain weight in certain disease situations, such as during chemotherapy for cancer. Read more »
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The brain’s ability to perceive space expands like the universe |
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Professor Tanya Sharpee and team led a study that describes how neurons in the hippocampus represent space in a manner that conforms to a nonlinear hyperbolic geometry—a three-dimensional expanse that grows outward exponentially. This discovery provides valuable methods for analyzing data on neurocognitive disorders involving learning and memory, such as Alzheimer’s disease. Read more »
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Supplementation with amino acid serine eases neuropathy in diabetic mice |
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Professor Christian Metallo and team discovered that altered serine metabolism in diabetic mice leads to peripheral neuropathy—a finding that may provide a new way to identify people at high risk, as well as a potential treatment option. Approximately half of people with diabetes experience peripheral neuropathy, which can include weakness, numbness, and pain, primarily in the hands and feet. Read more »
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Leveraging technology to map the brain's neurons |
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Assistant Research Professor Uri Manor and collaborators at the Howard Hughes Medical Institute are using a new technology to map the brain's neurons. Their results will lead to a better understanding of the circuits in the brain and may advance medical approaches for many neurological conditions. View video »
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Salk scientists receive $1.5 million from Sol Goldman Charitable Trust to research multiple sclerosis treatments |
Professor Ronald Evans and an interdisciplinary Salk team have been awarded a two-year, $1.5 million grant from the Sol Goldman Charitable Trust, at the direction of cardiologist and Salk Trustee Benjamin Lewis. The award will fund a research project to explore connections between the gut, brain, and immune system in search of new therapies for patients with multiple sclerosis (MS). |
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Professor John Reynolds named 2022 AAAS Fellow |
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Reynolds has been named a 2022 Fellow of the American Association for the Advancement of Science (AAAS). Reynolds is among 506 new AAAS Fellows who were nominated by their peers for their distinguished efforts to advance science. He and his team use computational modeling and a variety of other techniques to study the brain mechanisms involved in perception and conscious awareness. Read more »
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Professor Kay Tye’s study named 2022 "Leading Research Achievement" by Brain & Behavior Research Foundation |
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In the study, published July 20, 2022, in Nature, Tye and team discovered the molecule in the brain responsible for associating good or bad feelings with a memory. The finding paves the way for a better understanding of why some people are more likely to retain negative emotions than positive ones—as can occur with anxiety, depression, or post-traumatic stress disorder (PTSD). Read more »
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Charlotte Rambla receives 2022 Jeanie Borlaug Laube Women in Triticum Early Career Award |
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Rambla, a postdoctoral fellow in the lab of Professor Wolfgang Busch, was awarded the 2022 Jeanie Borlaug Laube Women in Triticum Early Career Award by the Borlaug Global Rust Initiative, a program that provides professional development opportunities for women wheat researchers in the early stages of their career in recognition of scientific excellence and leadership potential. Read more »
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Salk’s Taneashia Morrell appointed vice chair of programs for San Diego County Bar Association’s Diversity, Equity, and Inclusion Executive Committee |
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Morrell, a contracts and licensing associate in Salk’s Office of Technology Development, will oversee two of the group’s four major DEI committees—Anti-Racism Committee and Dialogue on Diversity Committee—for 2023. Morell is also a member of the Black Association at Salk. |
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Your support powers groundbreaking research, and the people who bring it to life. |
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Salk scientists recently discovered that dietary supplementation with the amino acid serine, one of the building blocks that make up proteins, reduces the symptoms of peripheral neuropathy in diabetic mice. |
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Which of the following is NOT a particularly serine-rich food?
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Enjoy Salk science on your devices |
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Looking for a unique background image for your computer, Zoom meeting, iPad, or phone?
Designed by Salk’s science illustrator, the image below shows microproteins and small proteins called smORFs, which are potentially a rich source of uncharacterized regulators of metabolism. Learn more »
Credit: Salk Institute and Cell Metabolism.
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Contact Us
The Salk Institute for Biological Studies
10010 N Torrey Pines Rd
La Jolla, CA 92037
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About this newsletter
Salk’s email newsletter is published monthly with updates on recent scientific publications, media coverage, awards, grants, events, and other timely information for Salk supporters and science enthusiasts.
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