Editor's Note
Eighty‐seven unique turmeric dietary supplements were sampled from the retail market; a majority (94%) contained turmeric‐derived curcuminoid extracts (TD‐CE), which were combined with other bioactives such as piperine in some products. Curcuminoid content was within 80% of anticipated for a majority of products analyzed, but curcuminoid composition (% curcumin) did not meet USP criteria for TD‐CE in 59% which may suggest possible unlabeled use of synthetic curcumin in some products. Lead content exceeded USP limits in only one product and residual solvent levels were quantified within USP‐specified limits in all samples tested.
Abstract
Scope
Turmeric is a top selling dietary supplement (DS) in the United States with rapidly expanding usage. Therefore, turmeric DS formulations available for sale in an urban US retail marketplace were analyzed, and point of sale information was related to measures of quality relevant to safety.

Methods and Results
Eighty‐seven unique turmeric DS were identified; a majority (94%) contained turmeric‐derived curcuminoid extracts (TD‐CE), which were combined with other bioactives in 47% of products, including piperine (24%), an additive that could alter the metabolism of concurrent medications. While curcuminoid content was within 80% of anticipated for a majority of products analyzed (n = 35), curcuminoid composition (% curcumin) did not meet USP criteria for TD‐CE in 59% and was suggestive of possible unlabeled use of synthetic curcumin in some. Lead content was associated with inclusion of turmeric root and exceeded USP limits in one product. Residues of toxic class 1 or 2 solvents, which are not needed for TD‐CE isolation, were present in 71% of products, although quantified levels were within USP‐specified limits.

Conclusion
Assessment of turmeric DS quality at point of sale is difficult for consumers and may best be managed in partnership with knowledgeable health care professionals.