eNewsletter | August 7th, 2017.

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2018 Gund-Harrington Scholar Award

Grant Program Seeks to Hasten the Development of Vision-Restoring Therapies..

The Gund-Harrington Initiative for Fighting Blindness announces the call for proposals for the 2018 Gund-Harrington Scholar Award. The Gund-Harrington Scholar Award supports innovative research efforts that could prevent, treat or cure blindness resulting from inherited retinal degenerative diseases. The Gund-Harrington Scholar Award is part of the Gund-Harrington Initiative for Fighting Blindness and sponsored by Foundation Fighting Blindness and Harrington Discovery Institute.

The competition is open to investigators at accredited academic medical centers, research institutions and universities in the U.S. and Canada. Applicants must have a PhD or MD degree (or equivalent) and demonstrate exceptional promise.

Letters of Intent are now being accepted through midnight on October 25, 2017.

Read on...

Researchers get better at tweaking the genomes of human embryos

Scientists for the first time have successfully edited genes in human embryos to repair a common and serious disease-causing mutation, producing apparently healthy embryos, according to a study published on Wednesday. The research marks a major milestone and, while a long way from clinical use, it raises the prospect that gene editing may one day protect babies from a variety of hereditary conditions.

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Call for proposal :

The purpose of the Genopole Thematic Incentive Actions, referred to by their French acronym “ATIGE”, is to contribute to the emergence of future scientific leaders by offering tenured researchers the possibility of creating a team within the already-established research units at the biocluster. The programs are intended for researchers who already have a position within a permanent public organism or are likely to attain one before the attribution of the ATIGE..

The first ATIGE grant is open to all research fields of the Genopole biocluster : genomics, bioinformatics and systems biology, proteomics, structural biology and biophysics, gene and cell therapy and regenerative medicine, applied life sciences and non-medical biotechnologies, metagenomics, biodiversity and microbial ecology

Application deadline : September, 4, 2017

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NCI study identifies essential genes for cancer immunotherapy

A new study identifies genes that are necessary in cancer cells for immunotherapy to work, addressing the problem of why some tumors don’t respond to immunotherapy or respond initially but then stop as tumor cells develop resistance to immunotherapy.

Working with a melanoma tumor cell line, the researchers used a gene editing technology called CRISPR that “knocks out,” or stops the expression, of individual genes in cancer cells. By knocking out every known protein-encoding gene in the human genome and then testing the ability of the gene-modified melanoma cells to respond to T cells, they found more than 100 genes that may play a role in facilitating tumor destruction by T cells.

Read on...

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