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Katalin Kariko of Hungary and Drew Weissman of the United States have won the 2023 Nobel Prize in Physiology or Medicine for their discovery of nucleotide base modifications, the Nobel Prize Committee at the Karolinska Institute in Sweden announced. These findings were the primary factor that enabled the development of effective mRNA vaccines against COVID-19 infection.
The success of mRNA vaccines against COVID-19 may signal a new, more successful, chapter in the continued battle to develop effective preventative measures against other viruses such as RSV. In addition, advances in the characterization, and structural resolution, of the RSV surface fusion glycoprotein have revolutionized RSV vaccine development by providing a new target for preventive interventions.
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