New York News in Research: June  2017

Introducing Sema4: A Spinout Company of the Mount Sinai Health System

The  System  Mount Sinai Health System announced that it has spun out several genetic testing and data sciences components from its Department of Genetics and Genomic Sciences and the Icahn Institute for Genomics and Multiscale Biology into a for-profit company, Sema4 . Take a closer look.

SUNY Upstate Mental Health Researcher Applauds $20 Million State Investment

At SUNY Upstate Medical University, Dr. Stephen Glatt's lab primarily works to identify genes and environmental risk factors associated with mental health disorders, with the hope of improving diagnosis, intervention and treatments. Past research has helped identify a gene linked to schizophrenia.

Dr. Glatt says there's already lots of great work happening at SUNY Upstate, but additional funding could go a long way in helping the university be even more competitive.

"Funding will help bring more talented researchers, help grow our labs and expand our ability to make medical discoveries," he said about New York State's appropriation of $20 million for research at academic medical centers and $300 million to grow the life sciences sector.  Take a closer look.
University of Rochester Medical Center: Stem Cells May Be the Key to Staying Strong in Old Age

University of Rochester Medical Center researchers have discovered that loss of muscle stem cells is the main driving force behind muscle decline in old age in mice. Their finding challenges the current prevailing theory that age-related muscle decline is primarily caused by loss of motor neurons.  Take a closer look.
Columbia University Medical Center: New Lung "Organoids" In a Dish Mimic Features of Full-Size Lung

New lung "organoids"-tiny 3-D structures that mimic features of a full-sized lung-have been created from human pluripotent stem cells by researchers at Columbia University Medical Center (CUMC). The team used the organoids to generate models of human lung diseases in a lab dish, which could be used to advance our understanding of a variety of respiratory diseases.  Take a closer look.
University of Rochester Medical Center: A New Way to Slow Cancer Cell Growth

Researchers from the University of Rochester's Center for RNA Biology  have identified a new way to potentially slow the fast-growing cells that characterize all types of cancer. The findings  were made in kidney and cervical cancer cells in the laboratory. Take a closer look.
Weill Cornell Medicine: Patient-Specific Method Improves Monitoring of Leukemia Cells

A technique developed by Weill Cornell Medicine and NewYork-Presbyterian investigators can detect cancer cells surviving therapy in the most common form of leukemia in adults more sensitively and precisely than traditional microscopic observation.  Take a closer look.
Icahn School of Medicine at Mount Sinai: Engineering New Anti-Cancer Drugs from Old Medicines

An interdisciplinary collaboration including 45 researchers has discovered a new class of drug candidates that activates the tumor suppressor protein PP2A. These new compounds have been shown to inhibit the growth of lung cancer tumors in mice, and have implications for a broad array of intractable cancers as well as neurodegenerative diseases such as Parkinson's and Alzheimer's.  Take a closer look.
NYU Langone Medical Center: Certain Immune Reaction to Viruses Causes Learning Problems

Researchers have discovered a mechanism by which the body's immune reaction to viruses like influenza and human immunodeficiency virus (HIV) may cause learning and memory problems.  Take a closer look.
Columbia University Medical Center: Pioneering Surgical Treatment for Depression

"Unless you've been there," observes Vito Randazzo, "you'll never understand the pain of mental illness." Vito suffered from nearly unendurable depression for more than a decade. But a new kind of neurosurgery has given him a reprieve.  Take a closer look.
University at Buffalo Jacobs School of Medicine and Biomedical Sciences: How Does Neuropathy Happen? New Research Reveals a Pathway and a Possible Therapeutic Option

Diabetic neuropathy is one of the most common complications of diabetes. While not life-threatening, it affects millions in the U.S. and elsewhere, and leads to limb amputations if left unchecked.   Take a closer look.
NYU Langone Medical Center: Cannabis Derivative Cannabidiol Reduces Seizures in Severe Epilepsy Disorder

After years of anecdotal claims about its benefits, the cannabis derivative cannabidiol reduced seizure frequency 39 percent for patients with Dravet syndrome-a rare, severe form of epilepsy-in the first large-scale, randomized clinical trial for the compound.  Take a closer look.
Albert Einstein College of Medicine: Researchers Discover First Human Antibodies That Work Against All Ebolaviruses

After analyzing the blood of a survivor of the 2013-16 Ebola outbreak, a team of scientists from academia, industry and the government has discovered the first natural human antibodies that can neutralize and protect animals against all three major disease-causing ebolaviruses.  Take a closer look.
SUNY Downstate Medical Center: Three Types of Work Stress Increasing in the U.S., According to SUNY Downstate Researchers

Researchers at SUNY Downstate Medical Center's School of Public Health  have determined that two stressful work characteristics, low job control and "job strain" - that is, high-demand, low-control work -  have been increasing in the U.S. since 2002.  Take a closer look.
Albert Einstein College of Medicine: NIH Funds NYC Center for AIDS Research

The National Institutes of Health has awarded researchers at Albert Einstein College of Medicine, The Rockefeller University, and The City University of New York Graduate School of Public Health and Health Policy (CUNY), a $7.5 million grant for the Center for AIDS Research focused on preventing HIV transmission and ending the AIDS epidemic.  Take a closer look.
New York Medical College: Professors of Physiology Receive One-Year $410,000 Continuation for "Ferrochelatase & Guanylate Cyclase Regulation in Vascular Dysfunction" from the NIH.

The grant will enable New York Medical College to develop an understanding of how mitochondrial oxidant mechanisms promoted by various metabolic and hypertension-associated vascular diseases potentially disrupt the biosynthesis of heme by ferrochelatase and impair heme-dependent regulation of a vasodilator mechanisms controlled by cyclic GMP generation by guanylate cyclase.
University at Buffalo President Urges Resistance to Federal Cap on Research Costs

Citing the significant harm that would be imposed on their institutions and on the nation's research endeavors, Satish K. Tripathi, president of the University at Buffalo, and Candace Johnson, president and CEO of Roswell Park Cancer Institute, strongly urged members of the Western New York congressional delegation to resist a Trump administration budget proposal to cap federal spending on costs essential to conducting research.  Take a closer look.
NYIT College of Osteopathic Medicine: A Cut in Research Would Wound U.S.

NYIT researcher In Newsday:  Scientific research is a critical national investment, providing strong economic and societal benefits along with new knowledge that helps us all.  Scientific discoveries in my area of expertise, microbial pathogenesis, allow us to prevent and combat rare illnesses like Legionnaires' disease or prevalent infectious ailments like Lyme disease that affect New Yorkers far and wide. Take a closer look.
New York Medical College: Department of Family and Community Medicine Hosts Fifth Annual Research Day

The Department of Family and Community Medicine hosted its Fifth Annual Research Day on May 10 in the Skyline dining room to showcase the research of students, residents and faculty. Sonia A. Velez, M.D., J.D., assistant professor of family and community medicine and interim chair of the Department of Family and Community Medicine, welcomed the audience, noting the increasing focus on research in family medicine and prevention and population health across the nation.