Briley Jeter and Miriam Zanovello, M.S. Biology students, each defended their theses on Aug. 6. Their research was part of a larger, ongoing project of Dr. Byer's, Associate Professor of Biology.
They investigated the use of phytochemicals in combination with traditional chemotherapeutics to treat two different types of cancer and evaluated the effect on cell viability and expression of cancer target genes.
Miriam treated ovarian cancer cells with a combination of cisplatin and EGCG, while Briley treated Glioblastoma multiforme with temozolomide and EGCG. Research results showed that their combination treatments increased cell death in cancer cells, but protected healthy control cells from the toxic effects of the cancer drugs alone.
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