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Autoimmune Disease Drug Development Solutions
At the heart of the immune system lies the precise regulation of self-antigen recognition and immune tolerance—an essential safeguard of human health. This balance is maintained through the dual mechanisms of central and peripheral tolerance. However, when the immune system is challenged by so-called "immune alarm signals," this delicate equilibrium can be disrupted, potentially leading to autoimmune diseases (AID).
Notably, studies have shown that approximately 10% of healthy individuals have low levels of autoantibodies detectable in their serum. While these antibodies may not cause overt symptoms, they could indicate an underlying imbalance in immune regulation.
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