Since the BRAIN Initiative's launch in 2013, FAS Research Development has disseminated information via this newsletter about all of the funding opportunities related to the initiative. We send this newsletter to a targeted list of faculty, including  faculty affiliates  of the  Center for Brain Science  (CBS) and the  Mind Brain Behavior  (MBB) Interfaculty Initiative. This project is being carried out in collaboration with the Center for Brain Science.  Please feel free to forward this newsletter  to interested colleagues. All Harvard University faculty and administrators may subscribe here , and recipients may unsubscribe at any time. For an archive of past newsletters, or for information about additional Research Development support (finding funding, proposal development resources, etc.), please visit the Research Development website .  
Funding Opportunities
OSP Deadline:  5 business days prior to submission 
Sponsor Deadline for Letters of Intent (requested): 30 days prior to full proposal deadline
Sponsor Deadlines for Full Proposals: May 15, 2018; October 29, 2018; May 1, 2019; October 29, 2019; May 1, 2020; October 29, 2020
Award Information:  Application budgets are not limited but need to reflect the actual needs of the proposed project. Awards are for three years of support. The NIH anticipates providing $10M per year to fund an estimated 15 to 20 awards.
   
This FOA seeks applications for proof-of-concept testing and development of new technologies and novel approaches for large-scale recording and manipulation of neural activity to enable transformative understanding of dynamic signaling in the nervous system. In particular, this FOA seeks exceptionally creative approaches to address major challenges associated with recording and manipulating neural activity, at or near cellular resolution, at multiple spatial and/or temporal scales, in any region and throughout the entire depth of the brain. It is expected that the proposed research may be high-risk, but if successful, could profoundly change the course of neuroscience research.
 
Proposed technologies should be compatible with experiments in behaving animals, and should include advancements that enable or reduce major barriers to hypothesis-driven experiments. Technologies may engage diverse types of signaling beyond neuronal electrical activity for large-scale analysis, and may utilize any modality such as optical, electrical, magnetic, acoustic or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. Where appropriate, applications are expected to integrate appropriate domains of expertise, including biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.   
OSP Deadline:  5 business days prior to submission 
Sponsor Deadline for Letters of Intent (requested): 30 days prior to full proposal deadline
Sponsor Deadlines for Full Proposals: May 15, 2018; October 29, 2018; May 1, 2019; October 29, 2019; May 1, 2020; October 29, 2020
Award Information:  Application budgets are not limited but need to reflect the actual needs of the proposed project. The maximum project period is four years of support. The NIH anticipates providing $10M per year to fund an estimated 15 to 20 awards.
   
Although invention and proof-of-concept testing of new technologies are a key component of the BRAIN Initiative, to achieve their potential these technologies must also be optimized through feedback from end-users in the context of the intended experimental use. This FOA seeks applications for the optimization of existing and emerging technologies and approaches that have potential to address major challenges associated with recording and manipulating neural activity, at or near cellular resolution, at multiple spatial and temporal scales, in any region and throughout the entire depth of the brain. This FOA is intended for the iterative refinement of emergent technologies and approaches that have already demonstrated their transformative potential through initial proof-of-concept testing, and are appropriate for accelerated development of hardware and software while scaling manufacturing techniques towards sustainable, broad dissemination and user-friendly incorporation into regular neuroscience practice.
 
Proposed technologies should be compatible with experiments in behaving animals, and should include advancements that enable or reduce major barriers to hypothesis-driven experiments. Technologies may engage diverse types of signaling beyond neuronal electrical activity for large-scale analysis, and may utilize any modality such as optical, electrical, magnetic, acoustic or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. Applications are expected to integrate appropriate domains of expertise, including where appropriate biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.
News & Announcements
Questions about this newsletter or proposal submission may be directed to:

Jennifer Corby
Research Development Officer
jcorby@fas.harvard.edu | 617-495-1590

To see previous BRAIN Initiative Funding Newsletters, please visit our  email archive.
Research Development | Research Administration Services | research.fas.harvard.edu