Published in the
, researchers have identified genetic variations that contribute to familial gastric cancer. Inherited mutations - which affect the PALB2, BRCA1 and RAD51C genes and have been implicated in other cancer types - impair a critical DNA repair mechanism called homologous recombination. These findings could improve preventive care and new gastric cancer therapies.
Meanwhile, other researchers have developed a technique to identify patients who are more likely to suffer recurrence of gastric cancer based on the degree of abnormal DNA methylation.
Check out the study here