New York News in Research: October  2017
Breast Cancer Breakthroughs Across New York State

Breast cancer affects approximately 1 in 8 women in the U.S. In 2017, it's estimated that about 30% of newly diagnosed cancers in women will be breast cancers. While prognoses have improved in recent decades, thanks to advances in biomedical research leading to new and improved treatments, there remains work to be done.

This work is happening at academic medical centers across New York State, where researchers have made important discoveries in recent years - discoveries that would not be possible without significant public funding. Take a closer look at NY achievements in the field.
Albert Einstein College of Medicine: Novel Treatment Causes Cancer to Self-Destruct Without Affecting Healthy Cells

Scientists at  Albert Einstein College of Medicine  have discovered the first compound that directly makes cancer cells commit suicide while sparing healthy cells. The new treatment approach, described in today's issue of Cancer Cell , was directed against acute myeloid leukemia (AML) cells but may also have potential for attacking other types of cancers.  Take a closer look.
NYU Langone Health: New Research System Finds & Targets Vulnerabilities in Lung Cancer Cells

Genetic changes that help  lung cancer thrive also make it vulnerable to a promising experimental drug, according to a study led by researchers from  Perlmutter Cancer Center at NYU Langone Health, and  published onlineOctober 2 in Nature Medicine.  Take a closer look.
Columbia University Medical Center: Esophageal Cancer "Cell of Origin" Identified

  Columbia University Medical Center (CUMC) researchers have identified cells in the upper digestive tract that can give rise to Barrett's esophagus, a precursor to esophageal cancer. The discovery of this "cell of origin" promises to accelerate the development of more precise screening tools and therapies for Barrett's esophagus and esophageal adenocarcinoma, the fastest growing form of cancer in the United States.   Take a closer look.
Albert Einstein College of Medicine: A Multi-Pronged Approach to Diabetes

Combine obesity, poor nutrition, lack of exercise and limited access to health care and you've got the perfect recipe for a type 2 diabetes epidemic. Those ingredients are all too plentiful in the Bronx, where the diabetes incidence exceeds all other boroughs and ranks among the highest in the nation.  Take a closer look.
Jacobs School of Medicine and Biomedical Sciences, University at Buffalo: Designed to Treat Type 2 Diabetes, Dapagliflozin Provides Significant Benefits to Type 1 Diabetic Patients

  A majority of patients with Type 1 diabetes who were treated with dapagliflozin, a Type 2 diabetes medicine, had a significant decline in their blood sugar levels, according to a new  study  published published in The Lancet Diabetes and Endocrinology Take a closer look.
Icahn School of Medicine at Mount Sinai: Rare Benign Tumors Hold the "Genetic Recipe" to Combat Diabetes

Rare benign tumors known as insulinomas contain a complicated wiring diagram for regeneration of insulin-producing human beta cells, which may hold the key to diabetes drug development, researchers at the Icahn School of Medicine at Mount Sinai report.  Take a closer look.
Mental Health
Stony Brook Medicine: E-Mental Health Tool May be Key for Astronauts to Cope with Anxiety, Depression in Space 

A clinical trial of an innovative e-mental health tool led by a Stony Brook University psychiatry professor to help address stress, anxiety and/or depression began on September 18. The trial is designed to inform the delivery of mental health treatments for astronauts on long duration space missions.  Take a closer look.
University of Rochester Medical Center: Earlier School Start Times May Increase Risk of Adolescent Depression and Anxiety, Study Says

Teenagers with school starting times before 8:30 a.m. may be at particular risk of experiencing depression and anxiety due to compromised sleep quality, according to  a recent URMC study. T he study , recently published in Sleep Health , not only reinforces the theorized link between sleep and adolescent mental health, but is among the first to demonstrate that school start times may have a critical impact on adolescent sleep and daily functioning.   Take a closer look.
Columbia University Medical Center: Drugs Can't Stop Alzheimer's. A New Model of the Disease Explains Why.

A new model of Alzheimer's disease - proposed by scientists at Columbia University Medical Center and Weill Cornell Medicine - may explain why clinical trials of potential Alzheimer's drugs have a high failure rate. Take a closer look.
University of Rochester Medical Center Joins Landmark Brain Development Study
 The University of Rochester Medical Center (URMC) is participating in what is being characterized as the largest long-term study of brain development and child health. The study will follow the biological and behavioral development of more than 10,000 children from ages 9-10 through early adulthood Take a closer look.
Other Studies
Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo: In Obese Adults and Children, the Microbiome Plays Key Role in One of the most Common and Serious Liver Diseases

New clues to non-alcoholic fatty liver disease (NAFLD), which affects nearly all obese adults and a rising percentage of obese children, have been reported in a  paper published earlier this month in the journal Gut.   Take a closer look.
Icahn School of Medicine at Mount Sinai: HealthDay Reports on Rapid, Easy Zika Test Developed

A new fast, easy and cheap "dipstick" test for the Zika and dengue viruses could revolutionize public health response to dangerous tropical germs, a new study reports. The test accurately diagnoses Zika and dengue and can tell the two mosquito-borne viruses apart, an area in which commercially available tests now stumble.  Take a closer look.
NYU Langone Health: Mice Delivered by C-Section Gain More Weight Than Those Delivered Naturally

  Mice born by cesarian delivery, or C-section, gained on average 33 percent more weight in the 15 weeks after weaning than mice born vaginally, with females gaining 70 percent more weight. This is the finding of a study led by researchers from NYU School of Medicine and published online on October 11 in Science Advances .   Take a closer look.
Weill Cornell Medicine's Clinical and Translational Science Center Awarded $45.3 Million NIH Renewal Grant

Weill Cornell Medicine has received a $45.3 million renewal grant from the National Institutes of Health's Clinical and Translational Science Awards Program to continue funding its multi-institutional Clinical and Translational Science Center (CTSC) until 2022.  Take a closer look.
SUNY Downstate Awarded $10 Million from National Institutes of Health

SUNY Downstate Medical Center has been awarded a $10 million grant from the National Institutes of Health (NIH) to form a translational health disparities research program, with a focus on recruiting and training underrepresented minority scientists.
Funding will provide resources for junior faculty endowments, research fellowships, and recruitment of underrepresented minority students from area partner colleges to study translational health disparities and population health research.  Take a closer look.
New York Medical College: NYMC Receives $150,000 Grant from Hyundai Hope On Wheels

NYMC was one of 40 recipients of the 2017 Hyundai Hope On Wheels Grants, which fund research projects with the greatest potential to improve the lives of children battling cancer.
Take a closer look.
Zucker School of Medicine at Hofstra/Northwell: Noted Cardiac Surgeons Join Faculty

  Brian Lima, MD , and Syed Hussain, MD - cardiac surgeons with expertise in heart transplant and all types of adult cardiac surgery - have joined the heart transplant center at the Sandra Atlas Bass Heart Hospital at North Shore University Hospital  (NSUH) and the academic faculty at the Donald and Barbara Zucker School of Medicine at Hofstra Northwell.   Take a closer look.
Other News
Albany Medical Center: 'CRISPR' Scientists Receive America's Most Distinguished Prize in Medicine

For their roles in the creation of a remarkable gene editing system that has been called the "discovery of the century," five researchers were presented with the 2017 Albany Medical Center Prize in Medicine and Biomedical Research. Take a closer look.
SUNY Downstate's Incubator Program Launches Company Revolutionizing Bone Marrow Transplant Process

A biotech start-up company supported by SUNY Downstate Medical Center's Biotech Incubator has created a revolutionary new process for conditioning patients to receive bone marrow transplantation. In recognition of its technological advances, HemoGenyx is now the only Brooklyn-based company publicly listed on the London Stock Exchange.  Take a closer look.
Weill Cornell Medicine: Daedalus Fund Supports 15 Investigators

Fifteen winners (fourteen projects) have been selected for the fourth round of the Daedalus Fund for Innovation awards, a pioneering Weill Cornell Medicine program that helps advance promising applied and translational research projects and emerging technologies that have commercial potential Take a closer look.
New York Medical College Goes Gold for Childhood Cancer Awareness Month

The NYMC community gathered to show their support for Childhood Cancer Awareness Month and raise money for the Pediatric Cancer Research Foundation on September 19.  Take a closer look.