CCTS Digest 2.13.15 | www.uab.edu/ccts
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In This Issue
A CCTS Valentine from Darwin to You
image credit: The Daily Mail


In honor of Darwin Day (Thursday, Feb. 12-link: Official Darwin Day website), Friday the 13th (today-link: "13 Things to Know About Friday the 13th), and Valentine's Day (tomorrow, Feb. 14-link: "Say I Love You With Science," from Science Friday), we extend our sincerest wishes for a wonderful weekend!


It's also the weekend before Mardi Gras, and with a nod to our Partners in Louisiana, we hope you laissez les bons temps roulez just a little bit this weekend (or live vicariously by watching the parades on the NOLA Mardi Gras Parade webcam.)


Are you a mentor? Do you want to learn how to be one?

Each April for the past couple of years, the 
Office of Postdoctoral Education together with the Vice Provost for Student and Faculty Success has facilitated a UAB Mentoring Academy for new and junior faculty from across campus. The purpose of this event is to provide these faculty with information about best mentoring practices as well as the nuts and bolts of hiring and training grad students and postdocs here at UAB.

This year, we are excited to announce that this event has evolved into a 'Mentoring Week' with the following activities planned:

Tuesday, April 21, Dr. Kenneth Gibbs from the NIH will serve as our keynote presenter and will speak on effective mentoring practices. This event will be held in the Edge of Chaos at noon and will be open to all trainees and faculty.

Wednesday, April 22, Theater Delta, from Raleigh, NC, will perform an interactive mentoring skit and Q&A session. This event will be held in Bevill Biomedical Research Building (BBRB), Room 170 at 12pm and will also be open to all trainees and faculty.

Thursday, April 23, the full-day Mentoring Academy will be begin at 9am in the DoubleTree Hotel and will include interactive discussions and networking opportunities for participants; it will end at approximately 4pm. This day will be open to only new and junior faculty from across campus who have either been nominated by you or signed up directly.

Space for the all-day 'Mentoring Academy' on April 23rd will be limited. If you are interested in having any of your new and junior faculty participate and/or have questions about this event, email Lisa Schwiebert at lschwieb@uab.edu.


Mentor Training Group Forming for Spring

In addition to the Annual UAB Mentoring Academy, the CCTS provides complementary opportunities for faculty to engage in further discussion and training related to mentoring skills. Offered in two, 3-hour sessions, the workshops on mentoring draw from the nationally recognized University of Wisconsin-Madison Research Mentoring program. These include case-based discussions that explore "Maintaining Effective Communication," "Aligning Expectations," and "Assessing Understanding."  The second workshop addresses issues of "Equity and Inclusion," "Fostering Independence," "Promoting Professional Development" and "Developing a Mentoring Philosophy."  A new group is forming for Spring 2015. Please  contact the CCTS to note your interest in joining. 

Seminars, Symposia and Conferences

CCTS/CTO Research Seminar Series

Critical research implementation and management topics will be presented on the first and third Thursday at noon in PCAMS (1924 7th Avenue South). These topics will be of interest and relevance specifically to clinical research personnel including investigators, regulatory personnel, study coordinators and financial administrators. The goal of this new program is to fill in the gaps in information related to the implementation of clinical trials that have been identified by investigators and their research teams. Presented by Penny Jester, co-director UAB Clinical Trials Office. 





February Theme: Proper Reporting and Documentation


Topic: This program will provide an overview of the reporting SAEs and how to appropriately use Notes to File.  Tools and checklists will be provided. The Journal club will provide a review of relevant literature.  Courses are not sequential and can be attended separately.


Attendees: Investigators, Research nurse coordinators and managers, research nurses, and administrators.


Thursday, Feb. 19


Proper Use of Notes to File 

Partners: Please join us remotely via GoToMeeting:

Seminars, Lectures & Workshops

Monday, February 16

UAB Postdoctoral Research Day 

9 am-5pm

UAB West Pavilion Conference Rooms, Located on the 2nd Floor of UAB Hospital in the Spain Wallace Building


Visit the UAB Office of Postdoctoral Research for more info.


Tuesday, February 17

Changes to the NIH Biosketch Form and SciENcv Biosketch Generator Tool


PCAMS, 1924 7th Avenue South


Beginning with applications for research grants submitted for due dates on or after May 25, 2015, the NIH and AHRQ will require use of the new Biosketch format. Join Lee Vucovich, Asst. Director for Reference Services at Lister Hill Library and Melissa McBrayer, Program Director for the CCTS Training Academy for a hands-on workshop to learn more. The SciENcv biosketch generator tool makes compliance with the new format easier. Biosketch templates are also available for NSF bios!  SciENcv is an online tool that assists researchers in creating, formatting and saving biographical sketches needed for federally funded research.  It generates reference lists from My NCBI and imports grant information from eRA Commons. Once setup, it saves time. Light lunch is served on a first-come, first-served basis. Bring your laptop and please register.

Thursday, February 26

Pediatric Grand Rounds

"The UAB CCTS Program and Opportunities for Pediatric Clinician Scientists"

Bradley Conference Center
Children's Harbor 


Dr. Alyssa Reddy, Professor, Pediatrics; Director, Neuro-Oncology Program

Dr. Robert Kimberly, Director, UAB CCTS

Dr. Steven Rowe, Associate Professor of Medicine, Pediatric Pulmonary Medicine, and Physiology & Biophysics

Penny Jester, co-director, UAB Clinical Trials Office

Dr. Timothy Beukelman, Associate Professor, Division of Pediatric Rheumatology
Department of Pediatrics

Dr. Jeffrey Lebensburger, Pediatric Hematologist/Oncologist, Children's of Alabama


Geared toward physicians, fellows, residents, and medical students, this program will present an overview of opportunities afforded to pediatric clinician scientists with the CCTS. 


Very limited seating; event can be seen via the live link at: https://www.childrensal.org/LiveCMEOpportunity2

Please note: Lunches provided are for faculty, fellows, residents, medical students of Childrens of Alabama.  



Friday, February 27

2015 Bevill Neuroscience Symposium: Brain-Machine Interfaces


UAB Alumni House




This symposium, hosted by the UAB Comprehensive Neuroscience Center is free and will be providing free parking, refreshments and a reception. Registration closes Monday, February 23rd! Click here to register and to see the day's schedule of events and speakers. 



Wednesday, March 4



PCAMS 1924 7th Avenue South


Please join the UAB CCTS for our monthly forum, a chance to gather and discuss the latest innovations in new and ongoing research. This month we are proud to welcome Dr. James Cimino, MD, as inaugural director of the UAB Informatics Institute co-director of the CCTS. Click here to read more about it. Visit us in our CCTS headquarters, the Pittman building, for drinks, hors d'oeuvres and discussion. We look forward to seeing you then.


Thursday, March 12

Professional Skills Development Series

Refresher, Responsible Conduct of Research Training

Drs. Jeff Engler and Jennifer Greer, UAB Graduate School for Challenges of Ethical Authorship


UAB West Pavilion, Conference Room E


Participants will examine the challenges of authorship, academic style of writing, and ethical presentation of data in images and figures.  All trainees, fellows, participants, and scholars receiving support through any individual or institutional NIH training, career development award, research education grant, and dissertation research grant must receive personal instruction in responsible conduct of research. To meet the NIH requirement in RCR, trainees will need to take advantage of multiple training methods, not just one course.  Please register here.



Monday, March 16

UAB World Rare Disease Day Symposium


Children's Harbor, 1600 6th Avenue South, #200


Registration is now available online for $15. Click here for more information.

For more information, contact Shaila P. Handattu (hande@uab.edu)


Tues-Wed, March 17-18

10th Annual UAB Health Disparities Research Symposium 2015   

"The Science of Health Disparities: From Social Causes to Personalized Medicine" 

 DoubleTree Hotel, 808 20th Street South




 Click Here to: View Abstract GuidelinesSubmit an AbstractRegister for the Event


Announcing the 2015 Alabama Drug Discovery Alliance Seminar Series


Taking place Tuesdays at noon at PCAMS, 1924 7th Avenue South



Presented by the Alabama Drug Discovery Alliance and the UAB CCTS:


March 3: Introduction to Drug Discovery - Maaike Everts (UAB)

March 10: What Makes a Target Valid and Druggable? - Mark Suto (SR)

March 17: Assay Development in Drug Discovery - Indira Padmalayam (SR)

March 24: High Throughput Screening - Robert Bostwick (SR)

March 31: Toxicology in Support of Drug Development - Charles Hebert (SR)

April 7: Pharmacokinetics and ADME - Ed Acosta (UAB)

April 17: Medicinal Chemistry: From Hit to Lead - Corinne Augelli-Szafran (SR)

April 21: How to Submit an IND - Penny Jester and Maaike Everts (UAB)

April 28: Intellectual Property Aspects in Drug Discovery - Kathy Nugent (UAB)


To access slide decks from past presentations, visit: http://www.uab.edu/medicine/adda/

Light lunch provided. For more information email: adda@uab.edu
Training Opportunities

UAB CCTS Short-Term Research Training Program

8 Week Summer Program in Comparative Effectiveness and Patient-Centered Outcomes Research

June 8-July 31, 2015
Deadline for application:  5 pm, March 4, 2015
Notification will be by:  March 24, 2015
(Download a PDF of application guidelines) 


This 8-week program provides mentored research training experiences in patient centered outcomes research (PCOR) and comparative effectiveness research (CER) for medical students or other clinically-oriented doctoral students that have completed their first year of training.

Why CER and PCOR?  With an increasing, ongoing national focus, there is a growing need for training in these areas especially in the earliest stages of clinical training.

Who may apply?  Many applicants have finished their first year of medical school.  Students in other clinical doctorate programs and those that have been admitted to a pre-professional, clinical program are eligible to apply if they are able to meet the requirements of the program.

What else?  Trainees must devote full-time effort (40 hours week) for the duration of the program (June and July).  A stipend is provided; on-campus housing is available. 


In a time of accelerated scientific discovery, researchers are needed to translate research to the clinical setting. A national shortage of such investigators is well documented and specialized training is needed early in the career development process. Furthermore, with a continued national focus on comparative effectiveness research (CER) and patient centered outcomes research (PCOR), there is a growing need for training in these areas.

Clinically focused students in the earliest stages of training may have an interest but limited experience in research in PCOR, CER and related topics. The summer program at UAB provides an opportunity for a hands-on research experience leading to the generation of research products, all within a supportive, mentored research environment.


Questions?  Please contact the Center for Clinical and Translational Science (CCTS): ccts@uab.edu  /  205.934.7442


Starting next month, the UAB College of Arts and Sciences will offer training to junior faculty who are planning to apply for a National Science Foundation (NSF) CAREER Award. The NSF awards CAREER research grants to new faculty at universities who are at the rank of Assistant Professor (or equivalent) in any of the broad science and social science disciplines that are eligible for NSF grants.  


UAB's training will be led by former NSF CAREER awardee David Hilton (Department of Physics), with support from current awardees Ragib Hasan (Department of Computer and Information Sciences, Eugenia Kharlampieva (Department of Chemistry), and Karolina Mukhtar (Department of Biology). The three-session training program will walk applicants through the process of applying for and winning prestigious CAREER Awards from the NSF. All UAB faculty are invited to attend.


Sessions (content builds from session to session; attendance recommended at all 3):



* March 13 session -  Heritage Hall Room 102  

* April 10 and May 8 sessions -  Heritage Hall Room 500


Questions may be directed to Dr. David Hilton: dhilton@uab.edu




The Center for Outcomes and Effectiveness Research and Education (COERE), and the Minority Health and Health Disparities Research Center (MHRC) invite letters of intent for K-Scholar career development awards in Patient Centered Outcomes Research (PCOR).  These awards are supported by the Agency for Healthcare Research and Quality (AHRQ) Patient Centered Outcomes Research Institutional Award (K12).


This opportunity will support 3 PCOR K-Scholars for a period of two years to build capacity for the conduct of PCOR to enhance patient-centered care.  

Candidates must be junior-level, full-time UAB faculty OR be able to provide assurance of a staff appointment on or before August 1, 2015. Non-UAB candidates are eligible to apply.  Additional eligibility criteria are included with the full Letter of Intent instruction packet, available upon request. 

Please see the attached flyer  for additional information about the program.

Important Dates:

March 2, 2015 - Last day for receipt of letters of intent

May 4, 2015 - Full applications due


CONTACT:  For questions regarding eligibility, program requirements and the selection process or to request a Letter of Intent instructional packet, please contact Ryan Outman at routman@uab.edu




Check out the CCTS Funding Opportunities page on our website. 



Request for Applications for Alabama Drug Discovery Alliance Pre-Proposals: deadline March 23 8:30am

The RFA for 2015 ADDA pre-proposals is live. We will use a 2-stage process to identify new ADDA projects:


1) A PI (or multiple PIs) submit(s) a  pre-proposal with a maximum of 2 pages that will be reviewed by a scientific panel with expertise in various aspects of target validation and drug discovery - the instructions for which are attached.


2) After review, an invitation with instructions for a full proposal (maximum of 9 pages) will be sent to select PIs. Full proposals will be reviewed by a minimum of three scientific experts and the UAB Institute for Innovation and Entrepeneurship; the ADDA Advisory Board will select the final proposals based on these reviews and the ADDA portfolio.


Who can apply?

All UAB faculty and Southern Research investigators are eligible to apply, irrespective of affiliation or rank.

Click to read the entire application.


The deadline for the pre-proposals is on
Monday March 23, at 8:30am. Please read the RFA carefully to see what will and will not be considered to be eligible for funding.


For more information, email: adda@uab.edu.



    PCORI logo




PCORI issued six new PCORI Funding Announcements (PFAs) today. Five offer up to $88 million in support for a range of patient-centered comparative effectiveness research (CER) proposals under our national research priorities, with a pool of up to $12 million set aside for rare disease-focused studies. We also issued a new PFA targeting hepatitis C virus (HCV) infection, offering up to $50 million for up to four studies of key research questions in HCV diagnosis and treatment. Required Letters of Intent (LOIs) are due by 5 p.m. ET Friday, March 6. Find out more on the Funding Opportunities page on the PCORI website.


Contact the CCTS Research Commons (ccts@uab.edu; 4.7442) to learn more. Visit the site now for these and ongoing additions to the list!


Epidemiology/Biostatistics Clinic in The Edge of Chaos


This clinic provides the UAB community access to epidemiology and biostatistics resources.  Available most Mondays, 10am-2pm in The Edge of Chaos (Lister Hill Library, 4th floor).  Check the Edge of Chaos calendar for confirmation of meeting dates and times. 


UAB CCTS Biostatistics Clinic                                                    


Weekly on Wednesdays, 11:30am-1pm

February 4, 11, 18, 25 

PCAMS Building 1924 7th Avenue South


The Biostatistics Clinic is open to all faculty members, post-docs, fellows, residents, and students. Attendees are invited to bring statistical and methodological questions about on-going research projects, projects being planned, manuscripts in progress, responses to peer reviewers, and published articles. They are also invited to bring their laptops. Assistance will be provided by members of the CCTS BERD group. A light lunch is served.  


BERD Design Consultation Available Today

In support of Pilot & Feasibility Projects, the CCTS is offering design consultation through its Biostatistics, Epidemiology and Research Division (BERD).  A team of methodologists, including experts in Epidemiology (Gerald McGwin, Russell Griffin), Biostatistics (Robert Oster, David Redden, Leslie McClure, Paul Lin), and Statistical Genetics (Hemant Tiwari, Xiangqin Cui) are available to collaborate in the design of  the pilot proposals as well as in their review.  If other methodological expertise is required in the project design, the BERD will recruit the required expertise from among the network of UAB methodologists.


Please contact the BERD and request design consultation by emailing bstchair@uab.edu, calling 

(205) 934-4905 or connecting through Research Commons on the CCTS home page. 


UAB Center for Clinical and Translational Science |  ccts@uab.edu
 Pittman Center for Advanced Medical Sciences
1924 Seventh Avenue South
Birmingham, AL 35294