CCTS Digest 8.1.14 | www.uab.edu/ccts
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In This Issue
How Do Mom's Microbes Affect
 Pregnancy Outcomes?

That's the question behind a new research effort from OB/Gyn Rodney Edwards, M.D., who is exploring links between bacteria, preterm births and baby's long-term health. A recent article in UAB's research blog, The Mix, outlines the university's recent investments in microbiome research, supported by the CCTS bioinformatics team.


From the article: "Our microbes, collectively called the microbiome, most often live in harmony with our bodies. They support the immune system, help to digest food and keep the metabolism on track, and fight off disease-causing bacteria. But researchers suspect that mom's microbiome could play a role in when her children are born, and what happens to them as they grow. 

'Most people know about the microbes that colonize the gut,'says Rodney Edwards, M.D., an associate professor in UAB's Department of Obstetrics and Gynecology. 'But there are bugs in and on us in many other sites-our skin, our mouths, our noses, our genitalia.'"

Seminars, Symposia and Conferences

Throughout the summer, critical research implementation and management topics will be presented on the first and third Thursday at noon in PCAMS (1924 7th Avenue South). These topics will be of interest and relevance specifically to clinical research personnel including investigators, regulatory personnel, study coordinators and financial administrators. The goal of this new program is to fill in the gaps in information related to the implementation of clinical trials that have been identified by investigators and their research teams. Presented by Penny Jester, co-director UAB Clinical Trials Office. 



Thurs., August 7

FDA Audit:  Will you be ready?

Presenter:  Penny Jester, BSN, MPH and Susan Branscum, CTA


This program will review the how, what, where and why of an FDA audit. Attendees will leave with guidance and tools to assure they are prepared for an audit.

Attendees: Research nurse coordinators and managers, research nurses, HR personnel, investigators and administrators.


Thurs., August 21

Architecture of a Clinical Trial Program

Presenter: Tiffany Felix, M.S.   Assistant Director, Clinical Trials, USA Mitchell Cancer Institute


This program will provide an overview of the structure and function of a clinical trial program.

Attendees: Research nurse coordinators and managers, research nurses, HR personnel and administrators.


Wed. August 27

New!  Two new drop-in clinics on August 27th at noon.

The MyIDP or the Careers in Medicine sites both provide the opportunity to plan for your future goals in academic, research and professional skills.  You know the sites exist, but would you like to discuss ideas related to their use?  Join David Chaplin, MD, PhD, on August 27 from noon to 1pm in PCAMS (1924 7th Avenue S.). Bring your laptop.


Questions about NIH biographical sketches, MyNCBI and SciENcv (the new biosketch generator tool)?  Utilize a drop-in consult with Lister Hill's Lee Vucovich, also on August 27, from noon to 1pm in PCAMS.  Bring your laptop


August Visiting Lecturers:

Tues., August 12

Robert Califf, MD, Duke University Medical Center

"What Kind of Clinical Trials should a National Network Conduct? A Perspective from one year of the NIH HCS Collaboratory and the Startup of PCORI" 



Medical Towers, Room 634


Please register to attend this presentation at  http://drcaliffpresentation.eventbrite.com no later than August 8th.


Dr. Califf is Vice chancellor of clinical and translational research, director of the Duke Translational Medicine Institute (DTMI), and professor of medicine in the Division of Cardiology at the Duke University Medical Center in Durham, North Carolina, Robert Califf, MD, leads a multifaceted organization focused on the transformation of how discoveries are translated into improved medical care.  Prior to his role at DTMI, he was the founding director, Duke Clinical Research Institute (DCRI), a premier academic research organization. He is the editor-in-chief of American Heart Journal, the oldest cardiovascular specialty journal.

Wed., August 27

Ming Zhao, PhD, Program Director 

SBIR Development Center, National Cancer Institute 

"NCI SBIR and STTR: Advancing the Commercialization of New Cancer Innovations"


Noon-1 pm

Innovation Depot - Training Room

1500 1st Ave N, Birmingham, AL 35203


This session will provide an overview of:


-        SBIR/STTR eligibility requirements

-        NIH SBIR/STTR process and new cancer-focused grant funding opportunities from NCI

-        New NCI SBIR/STTR initiatives

-        Practical strategies and tips on how to successfully submit competitive research proposals



Opportunities for one-on-one meetings with Dr. Ming Zhao are available for attendees.  If interested in scheduling a one-on-one meeting, please contact Jennifer Croker, PhD (jcroker@uab.edu) before COB, Friday, August 22.


Registration is free - Space is limited. To learn more and to reserve your spot, please go to uab.edu/ccts.



Save the Date:

UAB Center for Exercise Medicine - 2nd Annual Symposium

Focus on Exercise Biology in Medicine and Rehabilitation


Sept. 26, 2014

8am-2 pm

Bradley Lecture Center/Children's Harbor - 4th Floor



Keynote Speaker:

Mark Tarnopolsky, MD, PhD, FRCP(C)

Professor of Pediatrics and Medicine

Director of Neuromuscular and Neurometabolic Clinic

McMaster University Medical Center

Hamilton, Ontario Canada




Check out the CCTS Funding Opportunities page on our website. 

We also list 

the latest research funding announcements, updated weekly, including these newest listings:





Translational and Clinical Studies to Inform Final Device Design

     PAR-14-300  U44 SBIR Cooperative Agreement - Fast-Track

    PAR-14-297  UH2/UH3 Phase Innovation Awards Cooperative Agreement

Translational and Early Feasibility Studies on the Path to Pre-Market Approval (PMA) or Humanitarian Device Exemption (HDE) 

     PAR-14-298  UH2/UH3 Phase Innovation Awards Cooperative Agreement

    PAR-14-299   U44 SBIR Cooperative Agreement - Fast-Track

Translational and Clinical Studies on the Path to 510(k)

     PAR-14-296  U44  SBIR Cooperative Agreement - Fast-Track

    PAR-14-295   UH2/UH3 Phase Innovation Awards Cooperative Agreement


NIH Transformative Research Awards (R01; RFA-RM-14-003 )


Visit the site now for these and ongoing additions to the list!


T32 Training Grant Deadlines Coming in September

The next NIH NRSA Institutional T32 training grant application deadline is September 25, 2014, for applications to the following NIH Institutes:

  • NCI
  • NHLBI (resubmissions only)
  • NIAID (only annual submission date)
  • NIGMS (predoc only)
  • NHGRI (competing renewals and resubmissions only)

The CCTS currently provides support in the preparation of NIH T32 training grant applications. Please visit the  CCTS Resources for Training Grant (T32) Directors website for additional assistance.


Epidemiology/Biostatistics Clinic in The Edge of Chaos


This clinic provides the UAB community access to epidemiology and biostatistics resources.  Available most Mondays from 10 a.m. to 2 p.m. in The Edge of Chaos (Lister Hill Library, 4th floor).  Check the Edge of Chaos calendar for confirmation of meeting dates and times. 

Wed. August 13

UAB CCTS Biostatistics Clinic                                                    

11:30 am-1:30 pm

PCAMS Building 1924 7th Avenue South


The Biostatistics Clinic is open to all faculty members, post-docs, fellows, residents, and students. Attendees are invited to bring statistical and methodological questions about on-going research projects, projects being planned, manuscripts in progress, responses to peer reviewers, and published articles. They are also invited to bring their laptops. Assistance will be provided by members of the CCTS BERD group. A light lunch is served.  



BERD Design Consultation Available Today

In support of Pilot & Feasibility Projects, the CCTS is offering design consultation through its Biostatistics, Epidemiology and Research Division (BERD).  A team of methodologists, including experts in Epidemiology (Gerald McGwin, Russell Griffin), Biostatistics (Robert Oster, David Redden, Leslie McClure), and Statistical Genetics (Hemant Tiwari, Xiangqin Cui) are available to collaborate in the design of  the pilot proposals as well as in their review.  If other methodological expertise is required in the project design, the BERD will recruit the required expertise from among the network of UAB methodologists.


Please contact the BERD and request design consultation by emailing bstchair@uab.edu, calling 4-4905 or connecting through Research Commons on the CCTS home page.







R01 renewal/resubmission deadlines are just around the corner! 

For ALL internal or external applications:

�        STUDY DESIGN:

Take advantage of CCTS expertise in study design, methods and biostatistics to optimize your proposal.  


Meet with a team of scientific experts who have perused your application as a first level of peer review.


Here are just a few comments from panel participants:  

  • "It was exactly what I needed."-Dr. Rita Cowell, Asst. Professor, Behavioral Psychology
  • "The CCTS Panel was very helpful." -Dr. Lynn Dobrunz, Assoc. Prof., Neurobiology
  • "The panel was AMAZING! There is no question in my mind that I submitted a MUCH stronger grant application as a result of this meeting. I am particularly impressed of how well the panel addressed the specific needs I expressed in my initial request to the CCTS. My prior understanding was that the CCTS provides feedback on presentations in the early stages of a grant application development, but maybe reviewing applications in later stages (e.g., prior to a resubmission) is another venue for the CCTS to support grant writers and improve the overall rate of funding success. THANK YOU!!!" -Dr. Kerstin Schroder, Assoc. Prof., Health Behavior 


You write the science, let the CCTS do the rest.

 Contact ccts@uab.edu for more information.


Save the Date: The Community Engagement Institute is Coming!
Join the UAB CCTS's One Great Community project and the Jefferson County Participation Board this fall on Friday, October 10, 2014, for a half-day event aimed at engaging members of our amazing community. Come join us and learn more about opportunities for collaborative research and service in the greater Birmingham area. Stay tuned for details!

UAB Center for Clinical and Translational Science |  ccts@uab.edu
 Pittman Center for Advanced Medical Sciences
1924 Seventh Avenue South
Birmingham, AL 35294

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