Volume 59 | February 28, 2023
|
|
A program of NIH’s National Center for Advancing Translational Sciences |
|
Sites with Signed
DUAs
356
|
|
Orgs with EHR Data Released into the Enclave
77
|
|
COVID-19
Positive
Patients
7,079,604
|
|
Rows
of Patient
Data
22.5 billion
|
|
Approved
N3C Research
Projects
444
|
|
|
N3C won the Grand Prize for the HeroX DataWorks Challenge
for Data Sharing!
The Federation of American Societies for Experimental Biology (FASEB) and the National Institutes of Health (NIH) sponsored the DataWorks! challenge,focusing on a bold vision of data sharing and reuse. The DataWorks! Prize is an annual challenge that showcases the benefits of research data management while recognizing and rewarding teams whose research demonstrates the power of data sharing or reuse practices to advance scientific discovery and human health.
The National COVID Cohort Collaborative was a Grand Prize winner!
We want to thank the amazing community that designed, developed and contributed to this resource, and we are extremely grateful for the wonderful research teams.
The N3C is the largest national, publicly available HIPAA-limited dataset in US history. The innovative data governance and engineering strategy and public-private-government partnership has made broad sensitive clinical data sharing possible. Clinical informatics has been siloed and competitive; N3C has galvanized sharing of data, methods, and artifacts; furnishing full provenance for rigor, reproducibility, and transparency; and attribution for all types of contributors. The unprecedented availability of this data has catalyzed 400+ collaborations collectively involving 4,500+ researchers from 300+ institutions in 25 countries.
Register to hear Melissa Haendel speak about "Democratizing Access to Clinical Data"
on Friday, March 10, 2023 at 9am/12pm ET
|
|
What the Research Community is Saying about N3C |
|
Kerrie DeMarco, PhD
Alliance Office Branch Chief
Division of Research Innovation and Ventures (DRIVe)
Biomedical Advanced Research Development Authority (BARDA)
Administration for Strategic Preparedness and Response (ASPR)
U.S. Department of Health & Human Services (HHS)
|
|
“N3C represents a truly amazing clinical data resource and a unique community to utilize that data for future EHR implementation. The Pediatric COVID-19 Data Challenge was an ambitious community challenge that leveraged N3C to catalyze the development of computational models to predict pediatric patients at risk for hospitalization and severe outcomes. Teams in the competition drew together multiple disciplines, spanned multiple geographic areas and ranged from academic institutes to large companies to a single citizen scientist. Some of these teams also leveraged insights and concept sets already developed from the N3C community. N3C continues to bring valuable resources to allow researchers to gain insights into COVID-19 and to develop capabilities for use in future pandemic response.” |
|
Expanded Focus
N3Community Real-World Data Forum
Effective March 13, 2023
Expanded Topics and Change in Frequency!
Forum topics expansion: Transitioning N3Community Forum from Covid-focused topics to a wider range of topics including Real World Data (RWD) analytics.
New Forum meeting pattern effective March 13, 2023: On every 2nd and 4th Monday at 5pm ET/2pm PT.
Forum Zoom change: There will be a new Zoom host. Registered forum attendees will be automatically moved to a new Zoom. Registered attendees will receive an email with a new Zoom link next month.
Share your thoughts: Looking for ways to bring relevant and exciting presentations to the Forum. Let us know if there are topics, presentations, speakers you would like to see: bit.ly/N3CForumFeedback
Read more about N3Community Forum Changes and updates here
|
|
REMINDER: All N3C publications and presentations must be submitted to the Publication Committee for review.
N3C researchers are reminded that in accordance with N3C Attribution & Publication Principles and N3C User Code of Conduct, all enclave data — whether as tables, figures, or text — must comply with an approved DUR and must receive download approval from the download committee. Compliance and approval are requirements before data leave the N3C enclave environment. Likewise all potential publications — whether full-length manuscripts, conference abstracts, posters, or presentations — (whether or not they include patient data) must be submitted to the Publication Committee for approval and tracking in advance of submission for peer review and/or preprint. Submission to the publication committee happens via the form at https://bit.ly/n3c-publication-intent. Currently, published works can be browsed at https://bit.ly/n3c-google-scholar; please report any questions, gaps or errors to n3c.pubs@gmail.com.
|
|
Calling all investigators, researchers, students, clinicians, scientists, educators, informaticists!
Do you have a novel N3C or EHR RECOVER approach or results to share with the medical informatics community?
This is your opportunity to submit your proposal to AMIA!
We encourage you to submit a proposal for AMIA 2023 Annual Symposium
Submissions are due to AMIA Tuesday, March 21, 2022 at 11:59pm ET.
To get approval in time, submissions are due to the N3C publication committee by Tuesday, March 7th.
Work describing fundamental informatics methods as well as systems and applications are both welcome for one of the programmatic themes:
Programmatic Themes
- Academic Informatics
- Clinical Informatics
- Clinical Research Informatics
- Consumer Health Informatics
- Public Health Informatics
- Translational Bioinformatics
Types of Submission
- Papers
- Student Papers
- Podium Abstracts
- Posters
- Panels
- Informatics Debate
- Workshops
- Systems Demonstrations
|
|
N3C No Meeting Week
To help our community with a positive and productive workload, CD2H-N3C will schedule several “No Meeting Weeks” throughout the year. Most meetings will be canceled. Impromptu meetings can still occur to push through action items as needed during no meeting week. Workgroups and Domain Teams should check with their Leads to determine meeting schedules for that week.
1st Quarter - March 13-17
2nd Quarter - May 29-June 2
3rd Quarter - September 4-8
4th Quarter - November 13-17
|
|
Google Drive access for N3C Researchers
If you are an N3C researcher who needs to access documents in the NCATS-owned Google Drive*, please onboard and / or update your preferred Google account here
*Note that NCATS has a business agreement with Google and documents in this drive are not mined by Google
|
|
The New Oral Health Domain Team
The Oral Health Domain Team is focused on understanding the impact of COVID-19 and Long COVID on the clinical progression, outcomes, and treatment optimization of dental patients. Our prioritized research will include 1) identifying emerging research questions and vulnerable populations in oral health peri pandemic and during the post-pandemic recovery, 2) developing electronic EHR phenotyping algorithms specific for oral diseases, 3) examining epidemiology of oral complications relating to COVID-19, 4) examining the impact of COVID-19 on oral diseases and risk factors, and 5) identifying clinical evidence for better treatments.
Team Meeting: 2nd Friday of the month at 12:30pm/3:30ET. Please email n3c-oral-health-dt@ctsa.io to join the Domain Team and get the meeting information.
|
|
Events
N3Community Forum
Presentations take place on select Mondays from 5–6 p.m. ET/2–3 p.m. PT. To attend these and future N3Community Forum presentations, please register here.
Missed an N3Community Forum or want to revisit a past Forum? You can find all the videos on our YouTube page.
March 6, 2023
Topic: Real World Data: Deidentification Methods, Considerations for Ethical AI and Data Distribution
Presenter: Brad Malin, PhD
Vanderbilt University
March 13, 2023
Topic: TBA
Presenter: TBA
March 27, 2023
Topic: TBA
Presenter: TBA
April 10, 2023
Topic: The future and the role of Cancer Data Semantics
Presenter: Umit Topaloglu, PhD and Robinette Renner, PhD
National Health Institute
|
|
If You are Interested in N3C Research Results and Conversations
Attend the Community Forum!
Please register for your Community Forum meeting link. After registering, you will receive a confirmation email from cd2h@uw.edu containing information about joining the meeting and you will also have the ability to download the .ics file to create calendar reminders for future Community Forums.
|
|
Help Us Give You Attribution for Your N3C Publications!
When you have a research product that is ready for publication or accepted for presentation, please submit it via the N3C Publication Intent Form, which will notify the Publication Committee of N3C output to be registered. (Research products include: manuscripts, posters, conference papers, blogs, press releases, podium presentations, etc.)
Per the N3C Attribution and Publication Principles, all manuscripts using N3C community resources must be reviewed by the Publication Committee. Non-manuscript products do not require review but should be submitted after they have been accepted by the conference to allow for promotion and tracking of collaborator accomplishments.
|
|
N3C Domain Teams
N3C Domain Teams enable researchers with shared interests to analyze data within the N3C Data Enclave and collaborate more efficiently in a team science environment. They include multidisciplinary Clinical Domains composed of subject matter experts, statisticians, informaticists, and machine learning specialists who focus on clinical questions surrounding COVID-19's impact on health. Cross-Cutting Domains have a varied focus that applies to multiple domains. These teams provide an opportunity to collect pilot data for grant submissions, train algorithms on larger datasets, inform clinical trial design, learn how to use tools for large-scale COVID-19 data, and validate results. N3C encourages researchers of all levels to join a Domain Team that represents their interests, or to suggest new clinical areas to explore.
|
|
Offboarding
As we approach the 3-year mark for the COVID-19 pandemic, it is a good inflection point to identify colleagues who have completed their efforts with CD2H/N3C projects and have transitioned to other great opportunities. If this is you, or perhaps your colleague, we would like to ask that you complete this 2-minute form (Bit.ly/cd2h-offboarding-form) to offboard CD2H and or N3C projects. You can continue to just get the newsletter if you wish.
We thank you for your tireless efforts in CD2H/N3C projects and look forward to working with you on many other projects.
|
|
The National COVID Cohort Collaborative (N3C) is a complementary and synergistic partnership among the Clinical and Translational Science Awards (CTSA) Program hubs, the National Center for Data to Health (CD2H), distributed clinical data networks (PCORnet, OHDSI, ACT, TriNetX), and other partner organizations, with overall stewardship by NIH’s National Center for Advancing Translational Sciences (NCATS). The N3C aims to improve the efficiency and accessibility of analyses using a very large row-level (patient-level) COVID-19 clinical dataset, demonstrate a novel approach for collaborative pandemic data sharing, and speed understanding of and treatments for COVID-19.
|
|
CD2H is supported by the National Center for Advancing Translational Sciences (NCATS)
at the National Institutes of Health
(Grant U24TR002306).
|
|
|
|
|
|
|
|
