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BCR-ABL Related Cell lines and In Vivo Models
(1) Human leukemia cell lines carrying BCR-ABL fusion gene, tested with Imatinib, Ponatinib, Olverembatinib and Dasatinib in vitro and in vivo
(2) Genetically engineered Ba/F3 cell line carrying BCR-ABL fusion gene, tested with Imatinib, Ponatinib and Olverembatinib in vitro and in vivo
(3) Genetically engineered Ba/F3 cell line carrying BCR-ABL-T315I mutation, tested with Imatinib, Ponatinib and Olverembatinib in vitro and in vivo
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CD79B-targeted ADC Related Models
(1) 12 human lymphoma CDX models expressing CD79B
(2) Lymphoma PDX models expressing CD79B
(3) Case studies: anti-tumor efficacy evaluation of R-CHOP combination chemotherapy and CD79B ADC in CD79B positive lymphoma PDX models
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Genetically Engineered ERα Mutant MCF-7 Human Breast Cancer Models
(1) Genetically engineered ERα Y537S and ERα D538G mutant MCF-7 cell lines
(2) Anti-tumor efficacy evaluation in ERα D538G mutant MCF-7 xenograft model
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