FEDERAL FUNDING OPPORTUNITIES
NEW! Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01 Clinical Trial Optional)
Purpose: To study incretin mimetics other than GLP-1 RAs or GLP-1/GIP-1 RAs, such as dipeptidyl peptidase (DPP)-4 inhibitors, must justify why the agent(s) they propose to study are more effective and/or have a more favorable side effect profile than GLP-1 or GLP-1/GIP-1 RAs.
Letter of Intent: January 5, 2025
Applications: February 5, 2025
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NEW! Cancer Tissue Engineering Collaborative: Enabling Biomimetic Tissue-Engineered Technologies for Cancer Research (R01 Clinical Trial Optional)
Purpose: To support the development and characterization of state-of-the-art biomimetic tissue-engineered technologies for cancer research. Collaborative, multidisciplinary projects that engage the fields of regenerative medicine, tissue engineering, biomaterials, and bioengineering with cancer biology will be essential for generating novel experimental models that mimic cancer pathophysiology in the context of a testable cancer research hypothesis.
Letter of Intent: January 5, 2025
Applications: February 5, 2025
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NEW! Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01 Clinical Trial Not Allowed)
Purpose: To advance research in cancer etiology and early detection biomarkers, utilizing the advantages of the unique biorepository resources of the NCI-sponsored Prostate, Lung, Colorectal, and Ovarian Cancer (PLCO) Screening Trial.
Letter of Intent: January 10, 2025
Applications: February 10, 2025
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NEW! Pragmatic Trials across the Cancer Control Continuum (UG3/UH3 Clinical Trial Required)
Purpose: To support research that tests the impact of cancer-related interventions on cancer-related outcomes across the cancer control continuum using a pragmatic trial study design. This NOFO will use the UG3/UH3 phased cooperative agreement mechanism.
Letter of Intent: January 14, 2025
Applications: February 14, 2025
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NEW! Innovative Approaches to Studying Cancer Communication in the New Information Ecosystem (R01 Clinical Trial Optional)
Purpose: to support meritorious research projects in three distinct domains related to cancer communication: 1) the utility and application of new cancer communication surveillance approaches; 2) the development and testing of rapid cancer communication interventions using innovative methods and designs; and 3) the development and testing of multilevel cancer communication models emphasizing bidirectional influence between levels.
Deadline: February 5, 2025
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NEW! Basic Research in Cancer Health Disparities (R01 Clinical Trial Not Allowed)
Purpose: To support innovative studies designed to investigate biological/genetic contributors of cancer health disparities, such as (1) mechanistic studies of biological factors associated with cancer health disparities, including those related to basic research in cancer biology or cancer prevention strategies, (2) the development and testing of new methodologies and models, and (3) secondary data analyses.
Deadline: February 5, 2025
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NEW! NCI Pathway to Independence Award (K99/R00 – Clinical Trial Not Allowed)
Purpose: To facilitate a timely transition of talented postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers.
Deadline: February 13, 2025
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NEW! Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)
Purpose: To conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of this initiative is to address key scientific questions relevant to cancer by supporting the analysis of existing clinical, environmental, surveillance, health services, vital statistics, behavioral, lifestyle, genomic, and molecular profiles data.
Deadline: February 16, 2025
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NEW! Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE) (R21 Clinical Trial Not Allowed)
Purpose: to study effects of different types of radiation used in radionuclide-based therapeutics (e.g., radiopharmaceutical therapy) on normal tissue, tumor cells and the tumor microenvironment.
Deadline: February 16, 2025
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The Metastasis Research Network (MetNet): MetNet Research Projects (U01 Clinical Trial Not Allowed)
Purpose: to provide support to promote research efforts on the use of integrative systems-level approaches to address a defined gap in metastasis research.
Letter of Intent: May 20, 2025
Applications: June 20, 2025
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NCI Small Grants Program for Cancer Research (NCI Omnibus) (R03 Clinical Trial Optional) (PAR-25-078)
Purpose: to provide support to well-defined projects in any area of cancer research using the NIH R03 small grant mechanism.
Deadline: February 24, 2025
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Notice of Funding Opportunity: Mechanistic links between diet, lipid metabolism, and tumor growth and progression (UH2 Clinical Trial Not Allowed)
Purpose: to provide support to applications that propose mechanistic investigations of the links between diet, lipid metabolism and tumor growth and progression. It is anticipated that this program will support fundamental studies designed to identify and define the molecular mechanisms through which lipid metabolism mediates tumor growth and progression, focusing specifically on the central role lipids play in linking diet with the biology of cancer; bridge the historically divided fields of nutrition and molecular metabolism; and stimulate research and tool development in this emerging area, which faces particular challenges because of the complexity of lipid biochemistry.
Deadline: February 14, 2025
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Notice of Funding Opportunity: Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)
Purpose: to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, sustainability, scale-up, and spread of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies (herein referred to collectively as evidence-based interventions). Studies that promote equitable dissemination and implementation of evidence-based interventions among underrepresented communities are encouraged. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful.
Deadline: February 16, 2025
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Notice of Funding Opportunity: Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)
Purpose: to stimulate translation of scientific discoveries and engineering developments in imaging, data science and/or spectroscopic technologies into methods or tools that address contemporary problems in understanding the fundamental biology, potential risk of development, diagnosis, or treatment of cancer.
Deadline: February 5, 2025
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Notice of Funding Opportunity: Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)
Purpose: to provide support to promote research efforts on novel scientific ideas that have the potential to substantially advance cancer research in statistical and analytic methods, epidemiology, cancer survivorship, cancer-related behaviors and behavioral interventions, health care delivery, digital health and data science, and implementation science.
Deadline: February 5, 2025
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Notice of Special Interest: Administrative Supplements for Assessing Capacity to Address Obesity for Cancer Prevention and Control
Purpose: to support ongoing developments in obesity prevention indicate that using multiple policy, systems, and environmental (PSE) approaches across the diverse sectors that influence obesity offer considerable promise, but few efforts have been made to carefully evaluate such whole of systems, or PSE, approaches. Foundational work is needed to help set the stage for investigators from academic institutions, cancer centers, other research organizations, and community partners to lead collaborative groups to organize, implement, and evaluate such approaches. Furthermore, determining which specific combination of PSE approaches are most appropriate for a specific community requires significant preparatory work.
Deadline: February 3, 2025
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Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)
Purpose: to provide support to promote research efforts on the potential to reduce the burden of cancer through improvements in early detection, screening, prevention and interception, healthcare delivery, quality of life, and/or survivorship related to cancer; with such attributes, the proposed studies should also have the potential to improve clinical practice and/or public health.
Letter of Intent: January 5, 2025
Applications: February 5, 2025
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National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)
Purpose: to provide support to promote research efforts on early phase investigator-initiated clinical trials on cancer-targeted diagnostic and therapeutic interventions of direct relevance to the research mission of the NCI's DCTD and OHAM.
Letter of Intent: January 5, 2025
Applications: February 5, 2025
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Notice of Funding Opportunity: Biomedical Research Facilities (C06 Clinical Trial Not Allowed)
Purpose: eligible academic and research institutions to apply for funding to modernize existing or construct new biomedical research facilities. Applications will be accepted from public and private nonprofit institutions of higher education, as well as from non-profit research organizations. Applications from both research-intensive institutions and Institutions of Emerging Excellence (IEE) in biomedical research from all geographic regions in the nation are strongly encouraged.
Letter of Intent: December 16, 2024
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Notice of Special Interest: Conferences and Scientific Meetings in Cancer Biology
Purpose: Support innovative conferences, symposia, and workshops that explore basic, fundamental questions in areas of cancer biology
Deadline: December 12, 2024
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