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CPCE is accepting applications to our Pilot Grant Program through October 2.
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Spotlight on:
AAP Experience
Today starts pre-conference sessions and events at the American Academy of Pediatrics National Conference & Exhibition (AAP Experience) in Chicago. The conference runs through Tuesday September 19. A number of CHOP and CPCE faculty and research staff will be presenting at the meeting.
Click here
to see the schedule.
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Roberts Center Open House
Date: September 16, 2017
Time: 11:00 AM - 2:00 PM
Location: Roberts Center Lobby
There will be face painting, amusements, fun activities, refreshments, entertainment and the opportunity to see a stunning skyline view of the city from the 20th floor of the Roberts Center. CPCE staff will be there promoting our work.
Social Innovations to Address Immigrant Needs Symposium
Date: September 25, 2017
Time: 3:00 - 6:30 PM
Location: Calvary Center for Culture & Community, 841 S. 48th Street
At this time of heightened debate regarding the policy landscape and funding environment for immigration services and advocacy, this symposium examines successful and innovative models for delivering integration services to immigrant and refugee communities, supporting immigrant leadership development and promoting pro-immigrant policies at the municipal level and beyond. Keynote speakers are Jim Kenney, Mayor, City of Philadelphia and Nisha Agarwal, Commissioner, Mayor's Office of Immigrant Affairs, New York. For more information and to register, click
here.
CHOP Cores Day 2017
Date: September 28, 2017
Time: 10:00 AM - 2:00 PM
Location: Abramson Research Center Lobby
Learn about the services, technology, and expertise available to make your research more affordable, convenient, and efficient. Learn more
here.
Ellen Hyman-Browne Memorial Lecture
Date: October 5, 2017
Time: 4:00 PM
Location: Colket Translational Research Building, 1200B
The 2017 Keynote speaker is Ezekiel J. Emanuel, Vice Provost for Global Initiatives, the Diane v.S. Levy and Robert M. Levy University Professor, and Chair of the Department of Medical Ethics and Health Policy at the University of Pennsylvania. He will present "Ethics and Pricing of Innovative Drugs." For more information and to register, click
here.
Penn LDI 50th Anniversary Symposium
Date: October 5 - 6, 2017
Location: The Inn at Penn, 3600 Sansom Street
Join in a collaborative exchange of ideas on novel solutions to today’s health care challenges, together with leaders in health care policy and practice from academia, government, and the private sector. For more information and to register, click
here.
CHOP Pediatric Global Health Conference
Date: October 6 - 7, 2017
Location: CHOP Colket Translational Research Building
This conference will explore the state of immigrant and refugee health from a global, national and local perspective. Attendees will gain clinical, advocacy, public health and research tools to better serve these populations. Cases, discussions and stories will help us better understand the context of those who leave their homes seeking a better life. Find additional information online
here.
Mid-Atlantic Bioinformatics Conference
Date: October 10, 2017
Location: Colket Translational Research Building
Presented by the Department of Biomedical and Health Informatics (DBHi) at the Children's Hospital of Philadelphia and Penn's Institute for Biomedical Informatics (IBI), the second annual Mid-Atlantic Bioinformatics Conference will feature a distinguished line-up of internationally recognized speakers who will discuss the role of epigenetics and 3-dimensional chromatin organization as it relates to primary analysis, integration with large-scale data from adult and pediatric data sets, and the growing challenges in integrating epigenomic data with other types of omics data in the era of precision medicine. For additional information and to register, click
here.
mHealth Research Affinity Group Works In Progress
Date: October 16, 2017
Time: 12:30 - 2:00 pm
Location: Abramsom Research Center, 123-C
Sandra Amaral, MD, MHS will present "U-REAACT: a Multi-Center Trial to Engage Youth with Kidney and Urological diseases in their Treatment Adherence through text messaging, positive feedback and financial incentives." Gregory Tasian, MD, MSc, MSCE will present "PUSH: Integrating Technology, Financial Incentives, and Structured Problem Solving to Maintain High Fluid Intake Among Adolescents and Adults with Kidney Stones." Register
here.
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September 13, 2017
September 13, 2017
August 30, 2017
August 29, 2017
August 28, 2017
August 28, 2017
August 18, 2017
August 17, 2017
August 15, 2017
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August 7, 2017
August 1, 2017
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Little research attention has been paid to the occurrence of heart failure in children with complex congenital heart diseases. This paper describe the prevalence, risk factors, and costs associated with health failure in pediatric congenital heart disease patients.
There are limited follow-up studies examining surgical and catheter-based reinterventions in long-term survivors of the Fontan operation. In this study of Fontan survivors, two thirds of patients required surgical or catheter-based reintervention by 20 years. Families should be counseled that the Fontan is typically not the final stage of single-ventricle palliation.
In the primary care setting, there are racial and ethnic differences in antibiotic prescribing for acute respiratory tract infections (ARTIs). Viral ARTIs are commonly diagnosed in the pediatric emergency department (PED), in which racial and ethnic differences in antibiotic prescribing have not been previously reported. Dr. Gerber and colleagues from the Pediatric Care Applied Research Network (PECARN) sought to investigate whether patient race and ethnicity was associated with differences in antibiotic prescribing for viral ARTIs in the PED.
Navigating requests from parents or family caregivers not to disclose poor prognosis to seriously ill children can be challenging, especially when the requests seem culturally mediated. Pediatric clinicians must balance obligations to respect individual patient autonomy, professional truth telling, and tolerance of multicultural values.
Approaches for managing alert fatigue in the ICU are provided as a result of reviewing tested interventions that reduced alert quantity with the anticipated effect of reducing fatigue. Suggested alert management strategies include prioritizing alerts, developing sophisticated alerts, customizing commercially -available alerts, and including end user opinion in alert selection.
Dr. Akers and team conducted a multisite, single-blind, sham-controlled randomized trial in adolescents and young women having an intrauterine device (IUD) inserted to estimate the effect of a 1% lidocaine paracervical nerve block on pain during IUD insertion compared with a sham block in adolescents and young women. They found that a 10-mL 1% lidocaine paracervical nerve block reduces pain during IUD insertion compared with a sham block with pressure on the vaginal epithelium.
Youth living with HIV (YLWH) are less likely than older adults to achieve and sustain viral suppression. While treatment guidelines recommend decreased viral load (VL) monitoring in individuals with well-controlled HIV, the appropriateness of this strategy for adolescents is unknown. CPCE researchers conducted a retrospective cohort study to describe longitudinal viral suppression and identify incidence of, and risk factors for, virologic failure among YLWH at a US adolescent HIV clinic from 2002 to 2015.
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CCF currently is accepting applications for its Career Development Award, an annual research program that provides funding to clinical investigators who have received their initial faculty appointment to establish an independent clinical cancer research program. A single grant of $200,000 over three years will be awarded in support of research with a patient-oriented focus. To be eligible, applicants must be a physician within the first to third year of a full-time primary faculty appointment in a clinical department at an academic medical institution, without an existing career development award (such as K23, K08).
The American Association for Cancer Research is accepting applications for its AACR NextGen Grants for Transformative Cancer Research program. The annual program is designed to to stimulate highly innovative research from young investigators. Three-year grants of up to $450,000 will be awarded in support of creative, paradigm-shifting cancer research that might not be funded through conventional channels. To be eligible, applicants must have a doctoral degree. At the start of the grant term on July 1, 2018, applicants must hold a tenure-eligible appointment at the level of assistant professor; have held this appointment for no more than three years; and work at an academic, medical, or research institution anywhere in the world. AACR membership is required.
The Children’s Hospital of Philadelphia (CHOP) is soliciting pilot grants to support promising research efforts by senior fellows and instructors at CHOP. The goal of the program is to provide salary support for staff that can assist with the research objectives of the trainee. Funding will be for 1 year at $50,000 with an additional year of funding contingent on success towards the research objectives.
CHOP is soliciting pilot grants to stimulate new research initiatives between CHOP-based Assistant Professors and established PIs (based at CHOP or any Penn School). The goal of the initiative is to give junior PIs additional mentoring and research opportunities. For this purpose, a junior PI is defined as an Assistant Professor in the tenure or CE-track within his/her first 4 years of appointment. The mentoring PI is required to have a strong track record of mentoring trainees and/or junior faculty to independent research careers. Funding will be for 1 year at $50,000, with potential for an additional year of funding contingent on success towards the research objectives.
Translational Research Program was developed to encourage and provide early support for clinical research in leukemia, lymphoma, and myeloma focused on innovative approaches to treatment, diagnosis, and prevention. The program is designed to support new and innovative research that demonstrates high promise for translating basic biomedical knowledge to clinical application. Projects should be based on molecular, cellular, or integrated systems findings and be conceptually innovative. Grants are limited to a maximum of $600,000 over three years.
The Caplan Foundation for Early Childhood is intended to be an incubator of promising research and development projects that may ultimately enhance the development, health, safety, education or quality of life of children from infancy through seven years of age across the country. Each of its grants is made with the expectation that a successful project outcome will be of significant interest to other investigators or developers, within the grantee’s field of endeavor, and will be amenable to beneficial application or adaptation elsewhere. In essence, the foundation’s goal is to provide seed money for those imaginative endeavors, addressed to the needs of young children, which appear most likely to bear fruit on a national scale.
The Patient-Centered Outcomes Research Institute (PCORI) will release a new Funding Announcement (PFA) on Implementation of Effective Shared Decision Making Approaches in Practice Settings on September 1, 2017.
CPCE offers awards twice each year through its Pilot Grant Program. The purpose of this program is to promote and support CHOP investigators in clinical effectiveness pilot research studies that will attract external support for large-scale studies. Selected proposals will be supported for up to a maximum of $10,000 for one year. Projects should be able to be completed within one year.
The Greenwall Faculty Scholars Program in Bioethics is a career development award to enable junior faculty members to carry out innovative bioethics research. Applicants must be junior faculty members holding at least a 60% appointment in a tenure series at a university or non-profit research institute in the United States. Priority will be given to applicants who have not yet been considered for tenure, who have not received a comparable career development award, and whose work will have an impact on public policy, biomedical research, or clinical practice. The award supports 50% of a Scholar’s salary plus benefits for three years, plus $5,000 each year for limited project support and travel.
Grants of up to $20,000 are available to help support the research of faculty members or post-doctoral researchers affiliated with non-profit human service organizations in the United States and Canada. Areas of interest to the Fund are: studies to develop, refine, evaluate, or disseminate innovative interventions designed to prevent or ameliorate major social, psychological, behavioral or public health problems affecting children, adults, couples, families, or communities, or studies that have the potential for adding significantly to knowledge about such problems.
The American Kidney Fund Clinical Scientist in Nephrology (CSN) fellowship program enhances the training of nephrologists who wish to pursue an academic career and whose primary professional commitment is to scholarship in the provision of patient care. CSN fellows conduct prevention and outcomes research while receiving advanced training in essential skills such as medical ethics, biostatistics and epidemiology.
Last year, the NIH received approximately $30 billion in federal support. In spite of this amount, about 42,500 grants were not funded. To address these unfunded proposals, the NIH has a new Pilot Program that is designed to match researchers with nonprofit disease Foundations or with investments from private companies. Through a new collaboration between the NIH and the private contractor Leidos, researchers can now upload their unfunded NIH Proposals into an online portal at the Online Partnership to Accelerate Research (OnPAR). Foundations and other potential funders can review the NIH scores, and decide whether they might be interested in funding the Projects. Currently, this Pilot Program allows researchers with priority scores better than the 30th percentile to submit their abstracts. Interested Foundations might ask that a researcher send their full NIH Application along with its scores. The consensus opinion is that there are a lot of worthy grants being submitted to the NIH, but there is only so much funding available. OnPAR is one way of trying to match researchers with private Foundations.
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About CPCE
We are a pediatric research center dedicated to discovering and sharing knowledge about best practices in pediatric care by facilitating, organizing and centralizing the performance of clinical effectiveness research -- research aimed at understanding the best ways to prevent, diagnose and treat diseases in children. CPCE’s multidisciplinary team conducts research on a diverse range of clinical effectiveness topics grouped within four areas of research:
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