CTSI Announces Funding Awardees

2018-2020 KL2 Scholar Awardee:  Sanjib Chowdhury, PhD 

Dr. Chowdhury is a Research Assistant Professor for the BU School of Medicine in the Section of Gastroenterology. Dr. Chowdhury received his PhD in Cancer Research (2006-2010) and MS in Clinical & Translational Research (2014-2016) from the University of Nebraska Medical Center, where he was previously an Assistant Professor in the Department of Surgery.

African Americans have a significantly higher rate of incidence and mortality of colorectal cancer (CRC) compared to Caucasians. While some of this disparity is undoubtedly related to healthcare access, there is compelling evidence for a strong biological component. The overall goal of the BU-CTSI KL2 project is to determine the association and functional impact of high order chromatin remodeler cohesin stromal antigen 1 (SA-1) polymorphisms in CRC racial disparities.

2018 BU-CTSI Institutional Early Career Development Award:  Tehnaz Boyle, MD  

Dr. Boyle's current research focus is to test technological interventions to improve outcomes for sick and injured children requiring emergency care prior to arrival at hospitals. She has partnered with Boston Emergency Medical Services, the municipal advanced life support provider for the City of Boston, to study the impact of telemedicine in ambulances on emergency care for children. 

The overall goal of the BU-CTSI Institutional Early Career Development project is to use simulation as a research tool to pilot test intervention efficiency, learn clinical trial design, to test impact of interventions on important clinical outcomes, and to understand the ethics of emergency care research through a mentored research experience. 
The Core Voucher Recipients
We are pleased to announce that the following recipients have been selected to receive support for a portion of the labor, reagent, and sample processing costs for their proposed projects. 

The goal of this subsidy program is to lower the cost of entry for investigators who wish to use high-throughput technologies, including whole-genome gene expression microarrays and RNA sequencing.  

These platforms can provide highly valuable information about the regulation of biological processes in response to a given experimental condition (such as a disease state, drug treatment, or genetic manipulation), but they can also be prohibitively expensive to many investigators.

Konstantinos Alysandratos & Darrel Kotton
BUSM Center for Regenerative Medicine
Utilizing a PSC model system to unravel the pathogenesis of pulmonary fibrosis

Daniel Cifuentes & Elke Muhlberger
BUSM Biochemistry
Analysis of the tole of microRNAs during Ebola virus infection

Tsuneya Ikezu &Yang You
BUSM Pharmacology & Experimental Therapeutics
Comparison of microRNA profiling between human astrocytes-derived exosomes with and without IL-1B stimulation

Yuri Kim & Lee Quinton
BUSM Pathology & Laboratory Medicine
Mechanisms of Liver Injury and Hepatoprotection During Sepsis

Adam Labadorf & Thor Stein
BUSM BioInformatics
Gene expression signatures in mild to severe Chronic Traumatic Encephalopathy

Francisco Naya & Tiffany Dill
CAS Biology
RNAseq Analysis of Gtl2-Regulated Gene Programs in Skeletal Muscle Regeneration

Joseph Mizgerd & Antoine Guillon
BUSM Pulmonary Center
Transcriptome remodeling in alveolar macrophages of protected lungs

Maria Cardamone
BUSM Biochemistry
Neurl4 role in the regulation of mtDNA damage response and activation of the immune response

Marcello Panagia
BUSM Cardiovascular Medicine
Organ Crosstalk between the Heart and Brown Adipose Tissue in Heart Failure

Makoto Senoo
GSDM Molecular & Cell Biology
Epithelial Gene Programs in Sjogren's Syndrome

Lukasz Stawski
BUSM Arthritis Center
The functional biology of Oncostatin M in endothelial cells

Xiaoling Zhang
BUSM Genetics, Molecular Medicine
Identification of Novel Genes and Regulatory Networks associated with Alzheimer's Disease

Mini Sabbatical Announcements 2018

Matthew Applegate
Postdoctoral Associate
Will be working with Professors Hendon and Roblyer in their Lab at Columbia University exploring research on: Combined Near-infrared Spectroscopy and Optical Coherence Tomography probe for breast tumor margin assessment. 
Robin Ingalls
Professor of Medicine
Will be working with Dr Darville of North Carolina School of Medicine to broaden her research on: Biologic factors to predict infection concordance between sex partners 
Julie Mottl-Santiago
Director, Midwifery, Assistant Professor
Will be a visiting scholar at Brandeis University's Heller School of Social Policy and Management to develop economic evaluation skills using data from the Best Beginnings for Babies evaluation.

Help us continue our support by citing our grant number
in relevant publications:   1UL1TR001430 

All publications resulting from the utilization of CTSI resources are required to credit the CTSI grant by including the NIH Funding acknowledgment and must comply with NIH Public Access Policy.

Boston University  Clinical & Translational Science Institute
Accelerating Discoveries Towards Better Health 

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