January 2018 NEWSLETTER

CTSI Spotlight:
CTSI Kicks Off New Initiative  spotlight
  Research Job Connection 
  • Are you a PI who is looking for temporary research staff to help with your clinical or epidemiology study timelines? 
  • Are you a clinical or epidemiological research professional (Research Assistant, Study Coordinator, per diem Research Nurse or Lab staff) looking for extra hours or facing a job loss due to the ending of a grant?
To meet a need for the clinical and epidemiology research community, we are creating a pool of research professionals across BU and BMC. This pool will consist of employees who are looking for extra hours or a new position after a grant ends, to be matched to PIs looking for study help. These are staff members who are already familiar with BU/BMC systems/policies and have proper CITI/GCP credentials. 
PIs are often in need of temporary help with intensive recruitment or data collection timelines.  We are here to help!  The application process allows staff to apply to be part of the pool and we would then attempt to connect them to PIs who express interest or have a need. 

 For information on Research Job Connections contact:   
Britte Beaudette-Zlatanova    britte@bu.edu
Translational Science funding
The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) was officially established in fiscal year 2012 to transform the translational science process so that new treatments and cures for disease can be delivered to patients faster. NCATS, one of 27 Institutes and Centers (ICs) at NIH, strives to develop innovations to reduce, remove or bypass costly and time-consuming bottlenecks in the translational research pipeline in an effort to speed the delivery of new drugs, diagnostics and medical devices to patients.

Translation is the process of turning observations in the laboratory, clinic and community into interventions that improve the health of individuals and populations - from diagnostics and therapeutics to medical procedures and behavioral interventions.

T1: From Bench to Bedside

T1 research translates promising laboratory and "pre-clinical" findings into the care of patients. Such studies might include first testing in humans, physiology, toxicity, and efficacy studies of promising treatments. T1 research yields knowledge that demonstrates potential strategies for diagnosis, treatment, and prevention.

T2: From Bedside to Clinical Practice        

T2 research translates successful health application in humans into wider use in clinical practice in patient populations, and includes controlled observational studies and clinical trials, survey research, and other approaches to discerning the appropriateness of treatments and tests in clinical care. T2 research yields knowledge about the efficacy of the interventions in optimal clinical settings.

T3: From Clinical Practice to Widespread Clinical Practice and Care Delivery

T3 addresses the need to understand whether treatments, diagnostic tests, or other health strategies are applicable to the wide span of usual clinical care in practice. This might include clinical trials in broad ranges of settings and conditions and can also include creation of evidence-based guidelines for improved health care delivery, dissemination strategies, and widespread implementation of care strategies. T3 research yields knowledge about how interventions work in real-world settings.

T4: From Health Care Delivery to Community, Public Health, and Public Policy

T4 research translates effective health care delivery into improved community and population health, informs new policies, and includes outcomes research, population monitoring, the wider dissemination/implementation of improved practices/interventions, and health policy. T4 research yields knowledge that ultimately results in improved world-wide health.

Basic Research: Pre-Translational Research

Basic research is not part of the translational spectrum and focuses on identifying opportunities and potential approaches to health problems and includes a broad range of preclinical approaches employing animal models of human disease, human blood or cell lines, computational models, human physiological studies and non-interventional, correlational epidemiologic studies. Basic research yields knowledge about biological, social, and behavioral mechanisms and presentations of human disease.

Upcoming Events  events

Hiebert Lounge


The Boston University Clinical and Translational Science Institute (BU-CTSI) and the Grayken Center for Addiction at Boston Medical Center are pleased to announce their co-sponsorship of a symposium entitled:

"Addiction Medicine 2018: Translational Science at the Cutting Edge" 

Featuring ground breaking addiction medicine research and policy initiatives. The symposium will be held at the BU Medical Campus on May 3, 2018 in the Hiebert Lounge, 14th floor of the BUSM Instructional Building. Featured confirmed speakers will include Nora Volkow, MD, Director of the National Institute of Drug Abuse (NIDA/NIH), and Sandro Galea, MD, MPH, DrPH, Dean, Boston University School of Public Health. Additional speakers will outline innovative initiatives being explored at BU/BMC in addiction treatment, and a scientific abstract forum will be held to feature the diversity of addiction-themed research initiatives throughout the institutions. 

Research Professionals Network Workshop
So You Think You Know GCP?
Presenters: Gina Daniels and Mary-Tara Roth

Test your GCP knowledge in this interactive, challenging workshop! You'll work as a team to answer quiz questions and solve clinical research problems in alignment with GCP guidelines. Registration is required. You must be a member of the Research Professionals Network to attend RPN workshops.  
Research Recruitment & Retention (R3) Roundtable Series
Budgeting for Clinical Trials
Presenters: Terry Stone, Director of Clinical Trial Office and
Ridiane Dennis, RN, Manager of General Clinical Research Unit (GCRU)

Join us for lunch and an interactive discussion on research budgets. Learn from our experienced staff, gain insights to tackle your budgets with confidence.

Research Professionals Network Workshop (RPN)
Managing a Multicenter Trial
Presenter:  Courtney Diamond  
Clinical Research Resources Office (CRRO)
Fundamentals in the Conduct of Clinical Research:
BMC & BU Medical Campus Research Professional Staff Training.

Keep up-to-date on new regulations and resources to assist novice and experienced clinical research team members. Key topics and concepts to promote the ethical conduct research study activities will be covered during the two 4 hour sessions and will fulfill the GCP training requirement for clinical trials research for 3 years.  Spaces are limited.

7th Annual Community Engagement & Research Symposium
Hosted by UMass Medical School

Please come join us to build our shared capacity to address health issues in our communities by creating opportunities for people to: network, learn more about: each other's work and interests, make connections and plan for future collaborative work.  

Hiebert Lounge

The Evans Center for IBR & BU IBRO 
( Interdisciplinary Biomedical Research office) &  the CTSI present:
BU Technology Wonders: Potential Biomedical Applications

Join us for an afternoon exploring new technologies developed by BU investigators from the Charles River and Medical Campuses. 

Clinicians & basic and clinician scientists are invited to explore applications to their work. The afternoon will include 8-min presentations, separated with a coffee break and followed by wine & cheese around table discussions/explorations. Tables will be headed by the speakers and selected clinical chairs. These round table discussions are intended to give greater opportunities to directly explore specific topics in greater detail.
An anticipated outcome is follow up pilot grants to support 2-3 best
CR-Med campus collaborative technology development applications.
Address inquiries to Dr. Ravid via Robin MacDonald at:  remac@bu.edu
 Community Engagement  resources
 Building Relationships

In health research, investigators typically conduct research on a community. Community engaged research is an approach where investigators partner with community stakeholders to identify and address a common goal. Each partnership is unique. Some researchers conduct their work with the guidance of a group of community advisors. Others engage in full partnerships where community stakeholders not only drive the research questions but are part of the team every step of the way. No matter how a collaboration develops, we aim for shared leadership, empowered stakeholders, and transparency.
Community engagement is all about building relationships, which often take time to build.
For many researchers, getting started may be daunting, but the sooner you start planning the better. We offer a few different services at the BU CTSI to help partners come together, including:
  • Assistance connecting to patient and community advisors.
  • Communication workshops that use theater techniques to reduce jargon
  • Science caf├ęs to deliver results back to communities
  • A community engagement specific pilot grant
  • Consultation services
Tracy Battaglia,
Sharon Bak,
Nikki Spencer, 
Jennifer Pamphile

If you'd like to learn more, please email Nikki at  Nicole.spencer@bmc.org
  Sound Bites Soundbites

Connecting Community to Research: A Training to Increase Community Partnership In Research
Presented by Nicole Spencer, MSW, MPH & Jennifer Pamphile, BS

Connecting Community to Research is an awareness building training designed to introduce community members to research and the role they can play as partners throughout the process. The Community Engagement team at the BU CTSI created CCR and an accompanying toolkit to facilitate partnerships between researchers, patients, and community members. This webinar will introduce the CCR training toolkit and offer some lessons learned and tips for conducting these trainings with community groups.  

Creating a Comprehensive Search Strategy

Using Social Media for Participant Recruitment in Clinical Trials

A Foundation in RECap

REDCap Information

CTSI hosts Natural Language Processing Symposium

A Project Management Approach that Works
by Rebecca Sappington, PhD. edgeforscholars.org

The goal: implement a project management strategy that allows you to easily organize and synthesize data, track progress and strategize. Enter my strategy: the Storyboard!

What You Should Expect from Mentors
Article credit: https://edgeforscholars.org/

Recently, four senior investigators with long track records of mentoring successful scientists sat down to talk about what trainees and early career faculty  need most from mentors.  While it's key that a mentor tailor the training experience to the mentee's professional and personal goals, the panel agreed all mentors have these core obligations to their mentees. 

Help us continue our support by citing our grant number
in relevant publications:   1UL1TR001430 

All publications resulting from the utilization of CTSI resources are required to credit the CTSI grant by including the NIH Funding acknowledgment and must comply with NIH Public Access Policy.

Boston University  Clinical & Translational Science Institute
Accelerating Discoveries Towards Better Health 

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