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April 12, 2019
Case Western Reserve, Cleveland Clinic Launch New Era of Health Education with Samson Pavilion Dedication

The Samson Pavilion at the Health Education Campus
The Samson Pavilion at the Health Education Campus

This Wednesday, Case Western Reserve University and Cleveland Clinic launched a new era of health education, dedicating the centerpiece of the new campus, the Sheila and Eric Samson Pavilion.

"The dedication of the Sheila and Eric Samson Pavilion demonstrates the extraordinary value that the spirit of philanthropy brings to new generations of students. The Health Education Campus will have a major impact on advancing medical education and patient care," said Tom Mihaljevic, MD, Cleveland Clinic chief executive officer and president. "Its unique curricula and design will inspire health care professionals to be members of interdisciplinary teams and promote lifelong learning."

This spring, the four-story, 477,000-square-foot building opens to 2,200 students from Case Western Reserve's dental, nursing, and medical schools, including those from Cleveland Clinic Lerner College of Medicine. Students from the university's social work school also will come to the Samson Pavilion for shared coursework, but will continue to take the majority of their classes in their own newly renovated building on Case Western Reserve's main campus.  Read more>
Ponsky Appointed Chair of Department of Urology at University Hospitals Cleveland Medical Center, Director of the UH Urology Institute

The Case Comprehensive Cancer Center (Case
CCC) extends congratulations to Lee E. Ponsky, MD on his recent appointment to Chair of the Department of Urology at University Hospitals Cleveland Medical Center and Director of the UH Urology Institute.

Dr. Ponsky professor of urology in the Case Western Reserve University School of Medicine and member of the Case CCC's GU Malignancies Program. Read the release>
Cancer Center Seminar Series: "Targeting SHP2 for Cancer Therapy"
Apr 12, 12p | WRB Auditorium

Join us today at noon in the Wolstein Research Building Auditorium to hear National Institutes of Health (NIH) Distinguished Investigator  Benjamin G. Neel, MD, PhD present, "Targeting SHP2 for Cancer Therapy" Dr. Neel is  Director of the Laura and Isaac Perlmutter Cancer Center,  NYU Langone Medical Center and p rofessor, department of medicine at  New York University School of Medicine.

Dr. Neel's laboratory has a longstanding interest in signaling pathways regulating cell proliferation/
differentiation and their derangement in human disease, especially cancer. His group focuses on
signaling involving tyrosine phosphorylation, particularly by protein-tyrosine phosphatases (PTPs),
several of which his group discovered, including PTP1B, SHP1 and SHP2. He has also made significant  contributions to the understanding of the RAS/ERK pathway and its role in developmental diseases  termed RASopathies. More recently, his group has extended their interests to include the integrative  functional genomics of breast cancer and the cell of origin and nature of tumor-initiating cells in  high-grade serous ovarian cancer.

The Seminar Series  will  be
available to view via live stream. While we highly encourage you to attend in person to interact with our speakers and receive CME credit, we understand that may not always be possible. Presentations will not be recorded for later viewing, but you may watch the seminar in real time and ask questions via chat.  Watch live at noon>
Today! Build Your Own Sundae Fundraiser
1-3p | WRB Lobby

Immediately following Dr. Neel's presentation, join us in the WRB Lobby for an ice cream sundae bar!  Your $5 donation will benefit VeloSano Team Case CCC .
The Race 2019
May 12, 2019 | Legacy Village

The  Race is a 5K and one mile walk/run charity event  that empowers children and their families to make a difference in the lives of those touched by breast cancer by raising awareness and money for innovative breast cancer research. The Race has been held each Mother's Day for the past fifteen years, attracting approximately 1,500 people last year. To date, The Race, with help from friends, business associates and corporate sponsors, has raised over $1,250,000 for the fight against breast cancer. Proceeds from this year's event benefit the Case Comprehensive Cancer Center. 

Participate in  the 16th annual event as we work to eradicate breast cancer in our lifetime! Bring your family and make it a Mother's Day to remember.  Race participants will receive t-shirts and everyone can enjoy refreshments, clowns, bounce house, laser tag, face painting and more. Prizes will be given away throughout  the morning.  Join our team>
CTTE Short Course 2019
May 21-23, 2019 | CWRU
The  Skeletal Research Center  and the  Department of Biology  of  Case Western Reserve University  are pleased to present the eighteenth annual short course entitled, "Cell-Based Therapies and Tissue Engineering" running from May 21 through May 23, 2019 in Cleveland.

Registration is now open for the course  intended for graduate students, post-graduate students and health science professionals interested in Tissue Engineering with emphasis on the principles and detailed protocols used or being modeled for direct clinical use. The  course will involve morning lectures by eminent scholars, afternoon laboratories and lectures on the "how to" of cell cultures and cell-scaffold interactions. A syllabus from lecturers and labs will be available to all registered participants. more>
Open Funding Opportunities at the Case Comprehensive Cancer Center

Opportunities for Pilot Projects from VeloSano Bike to Cure
Deadline: April 30, 2019

GI SPORE Developmental Research Project Grant (DRP)
Deadline: May 15, 2019

GI SPORE Career Enhancement Program Award (CEP)
Deadline: May 15, 2019

Opportunities for Pilot Projects to Support Multi-Investigator Pilots
Applications accepted on a rolling basis

Applications accepted on a rolling basis
Funding Opportunities Related to the Cancer Moonshot 
Deadlines Vary

Cancer Moonshot Logo
Advancing Cancer Immunotherapy by Mitigating Immune-Related Adverse Events (irAE) (U01 Clinical Trial Not Allowed)(RFA-CA-19-044)

Metabolic Reprogramming to Improve Immunotherapy (R21)(PAR-16-229)

Asking These Questions About Your Cancer Risks Could Help Save Your Life
MSN - Feb 8, 2019
"If you have a first-degree relative with cancer, then the first screening colonoscopy should be at age 40 or 10 years younger than the youngest person affected with colon cancer in the family," says Smitha Krishnamurthi, MD, Cleveland Clinic oncologist and member of the Case CCC's Developmental Therapeutics Program.

What We Do
Oncology Times - Apr 5, 2019
"Your job as a leader of a cancer center is always to remember what it is that you do and what your cancer center does," says Brian Bolwell, MD, FACP, Deputy Director for Cleveland Clinic for the Case CCC in his latest contribution to Oncology Times.
NIH BULLETIN - Notices and Funding Opportunities
Notice of Preapplication Webinar for Administrative Supplements for Activities to Promote Human Immune-Representing Oncology Models

Notice of Correction to Eligibility Information in PAR-18-947 "Integrating Biospecimen Science Approaches into Clinical Assay Development (U01)"

Notice of Upcoming Webinar for the NCI Office of Cancer Survivorship

Notice of Correction to Award Information in RFA-CA-19-040 "Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

Notice of Correction to Award Information in RFA-CA-19-041 "Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)"

Notice of Correction to RFA-CA-19-047 "SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)"

Notice of Change to Key Dates for RFA-NS-19-016 "HEAL Initiative: Translational Devices to Treat Pain (UG3/UH3 Clinical Trial Optional)"

Notice of Change to Key Dates for RFA-NS-19-017 "HEAL Initiative: Translational Devices to Treat Pain (U44 Clinical Trial Optional)"

Notice of Change to Key Dates for RFA-NS-19-018 "HEAL Initiative: Clinical Devices to Treat Pain (UH3 Clinical Trial Optional)"

Notice of Change to Key Dates for RFA-EB-18-003 "HEAL Initiative: Translational Development of Devices to Treat Pain (U18 Clinical Trial Not Allowed)"

Requests for Applications

SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)(RFA-CA-19-047)
Deadline: Aug 9, 2019

Program Announcements

Paul Calabresi Career Development Award for Clinical Oncology (K12 Clinical Trial Optional)(PAR-19-242)
Fri, April 12
Cancer Center Seminar Series 
Benjamin G. Neel, MD, PhD
Director, Laura and Isaac Perlmutter Cancer Center
NYU Langone Medical Center
Professor, Department of Medicine
New York University School of Medicine
"Targeting SHP2 for Cancer Therapy"
12p WRB Auditorium

$5 Ice Cream Sundae Bar VeloSano Fundraiser for Team Case CCC
1-3p WRB Lobby
Mon, April 15
Genomic Medicine Institute
Elizabeth Shay
Eng Lab
Cleveland Clinic
"Oral Mycobiomic Profiles in Head and Neck Squamous Cell Carcinoma (HNSCC)"
Vishal Nanavaty, PhD
Ting Lab
Cleveland Clinic
"DNA Methylation Regulates mRNA Alternative Polyadenylation via CTCF and the Cohesin Complex"
12p NE1-205

Cancer Center Research Chalk Talk
Vinay Varadan, PhD
Assistant Professor, Case Comprehensive Cancer Center
1p WRB 3-136
Tues, April 16
Cancer Drug Discovery and Resistance
Eli Bar, PhD
Assistant Professor, Neurological Surgery
3p WRB 1-422D
Weds, April 17
Biomedical Innovation & Entrepreneur Club
CWRU Alumni Career Discussion Panel
4p SOM BRB 932
Thurs, April 18
Developmental Therapeutics Journal Club
9a NE6-218

Molecular Biology and Microbiology Virology Journal Club
de Boer Lab
1p SOM W203

Spring Update from the President and Provost
2p WRB Auditorium
Fri, Apr 19
Taussig Cancer Center Grand Rounds
Lilyana Angelov, MD
Edward Benzel, MD
Samuel Chao, MD
"Multimodality Management of Spine Tumors"
8a CA5-120

Research ShowCASE

*No Cancer Center Seminar Series; Series will resume Apr 26*

Nutrition and Center for Proteomics & Bioinformatics
Cynthia Ogden, PhD
Epidemiologist and Analysis Branch Chief
National Health and Nutrition Examination Survey (NHANES) Division
National Center for Health Statistics
Center for Disease Control and Prevention
"The Epidemiology of Obesity"
12p SOM BRB 105
Mon, April 22
Wolstein Research Building Faculty Meetings with Dr. Stan Gerson
12 WRB 3-136

Genomic Medicine Institute
Ignacio "Nacho" Mata, PhD Assistant Staff, Genomic Medicine Institute, Cleveland Clinic 
"Beyond Euro-centric medical research in Parkinson's disease: the LARGE-PD consortium"
12p NE1-205 
Tues, April 23
Cancer Imaging Monthly Meeting
Anirban Sen Gupta, PhD
Professor, Biomedical Engineering
1:30p CA5-120
Thurs, April 25
Developmental Therapeutics Journal Club
9a N E 6-218

Keri Lab Bake Sale for VeloSano
11a-2p BRB Lobby

Molecular Biology and Microbiology Seminar
Fengchun Ye
Karn Lab
1p SOM W203

Prostate Cancer Working Group Seminar and Journal Club
Jonathan Shoag, MD
Urologic Oncology Fellow
Cornell University
"Repurposing Drugs for Prostatic Disease: Using clinical data to identify drugs with activity against the prostate"
3p NE1-206
Fri, April 26
Taussig Cancer Institute Grand Rounds
8a CA5-120

Cancer Center Seminar Series
Shaun Stauffer, PhD
Director, Center for Therapeutics Discovery
Cleveland Clinic 
Member, Developmental Therapeutics Program
Case Comprehensive Cancer Center
" Using Structure-Based Design to Target Protein-Protein Interactions within the Mixed-Lineage Leukemia (MLL)-COMPASS Complex for Cancer Therapy"
12p WRB Auditorium


Deadline: Open

Deadline: Open

Deadline: Open
Case Comprehensive Cancer Center