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April 19, 2019
VELOSANO BIKE TO CURE
Join Team Case CCC for VeloSano 6!
Spring is here and we are gearing up for another VeloSano Bike to Cure Weekend! We encourage you to join in this moving and emotional event. Remember, the more that  the Case CCC participates, the more money we will collectively raise and therefore more money will be available for pilot grants to support new and innovative ideas. Plus, r esearchers who participate in VeloSano are eligible to apply for pilot funding.

Getting involved is easy:
  • RIDE with us during Bike to Cure Weekend July 19-21. Jerseys will be provided by the Case CCC. Contact team captains Caroline El Sanadi (cee17@case.edu) or Mary Wright (maw143@case.edu) our registration waiver code.
  • DONATE to any rider on our team or to the team as a whole.
  • VOLUNTEER for our cheer station and keep everyone motivated as they approach the last leg of their ride. Friends, families and children are welcome to join in the fun!
  • Support team fundraising efforts: 
    • Keri lab bake sale: Apr 25, 11a-2p, BRB lobby
    • Team Case CCC sundae bar: May 3, 1-3p BRB lobby 
    • Become a team sponsor
Opportunities for Pilot Projects from  VeloSano Bike to Cure
Deadline: April 30, 2019

With the generous support from VeloSano Bike to Cure 2018, the Case CCC is providing seed funding for 
highly innovative and potentially impactful  proposals that will generate key data for larger, nationally competitive grants. Projects must be aligned with at least one of the eight Case CCC Research Initiatives (Cancer Genomics, Cancer Immunotherapy, Brain Tumors, AYA cancers, Drug Discovery and Development, Women's Cancers, Community and Cancer Disparities, Computational Diagnostic Informatics) and the Center's Strategic Plan. Collaborative, multi-investigator projects are particularly encouraged and preferred. Learn more>
MEMBER/CENTER HIGHLIGHTS
Case Comprehensive Cancer Center Seeking Associate Director for Population Sciences
The Case Comprehensive Cancer Center (Case CCC) Case CCC logoinvites candidates to apply for the role of Associate Director (AD) for Population Sciences.

The AD for Population Sciences oversees the broad interests and approaches taken by the Case CCC, its consortium institutions and research members in all aspects of cancer population sciences. The Case CCC consortium includes CWRU, Cleveland Clinic, and University Hospitals, covering over 2.5M population lives and providing ample opportunities to develop high impact programs that study and affect population cancer prevention, detection and risk reduction, across the continuum of primary and secondary prevention, risk assessment, policy interventions, and tertiary prevention.

The AD coordinates with the AD for Cancer Disparities Research on efforts to mitigate the adverse effects of poverty, barriers to care, racial and other population disparities on cancer prevention, detection and treatment outcomes. Likewise, the AD links to the AD for Bioinformatics on studies of population health leveraging large databases, with the AD for Basic Research to facilitate the discovery of biologic risk factors that may affect populations, and the AD for Clinical Research to advocate for equitable access to clinical trials, managing the needs of special populations and efforts to link socioeconomic, genomic, ancestry and lifestyle risks to the burden of cancer.

The AD will have access to investigators focused on large health care databases, geospatial analyses, and identification and management of high-risk populations in the research programs of the cancer center. Through the executive committee and program leader meetings, the AD links transdisciplinary investigation to population efforts. The AD works with the Office of Training and Career Enhancement to offer training for trainees and junior faculty, in addition to cross-training for clinical and basic scientists with interests in population sciences. more>
MARK YOUR CALENDARS
Cancer Center Seminar Series: "Using Structure-Based Design to Target Protein-Protein Interactions within the Mixed-Lineage Leukemia (MLL)-COMPASS Complex for Cancer Therapy"
Apr 26, 12p | WRB Auditorium

Join us next Friday at noon in the Wolstein Research Building Auditorium to hear Shaun R. Stauffer, PhD present, " Using Structure-Based Design to Target Protein-Protein Interactions within the Mixed-Lineage Leukemia (MLL)-COMPASS Complex for Cancer Therapy." Dr. Stauffer is  Director of the Cleveland Clinic Center for Therapeutics Discovery and a member of the Case CCC's Developmental Therapeutics Program.


The Seminar Series  will  be
available to view via live stream. While we highly encourage you to attend in person to interact with our speakers and receive CME credit, we understand that may not always be possible. Presentations will not be recorded for later viewing, but you may watch the seminar in real time and ask questions via chat.  Watch live at noon>
Keri Lab Bake Sale for VeloSano Bike to Cure
Apr 25, 11a-2p | BRB Lobby

Stop by the BRB Lobby between 11 am and 2 pm on Thursday, April 25 and grab a sweet treat! Proceeds from the bake sale will benefit the VeloSano rides of graduate students Parth Majmudar and Katrina Piemonte in the Keri Lab. Each student has committed to raising $500 for cancer research. Cash & Venmo will be accepted as payment!
8th Annual Graft vs Host Disease National Symposium
Apr 26 | Cleveland Airport Marriott

The 8th Annual Graft vs Host Disease National Symposium focuses on cutting-edge research and new treatments and consists of two tracks: one designed for physicians and other health care professionals, and one for bone marrow transplant (BMT) survivors, their families and their caregivers.

The Meredith A. Cowden Foundation in collaboration with the Case Comprehensive Cancer Center, University Hospitals Seidman Cancer Center, and Cleveland Clinic Taussig Cancer Institute, created the National  GvHD Health Symposium in 2010 to raise awareness about Graft vs. Host Disease ( GvHD), to promote research to further our understanding of its cause, and to review cutting edge approaches to prevention and treatment.

Register today! Save $10 with code: CANCERCENTER. 
Cancer Center Scientific Series
May 1, 8:30a | WRB Auditorium

Please join us on Wednesday, May 1 as Case CCC researchers present findings from their pilot projects supported by the Research Innovation Fund. Researchers will offer an overview of their scientific discoveries and outlines of what comes next for their projects.

Breakfast will begin at 8:30am in the Cancer Center Conference Room, WRB 1-422D with presentations beginning at 9am in the auditorium, WRB 1-413.
The Case Comprehensive Cancer Center Scientific Series is a quarterly, extended conference featuring presentations by members who received pilot funding after competitive peer-review by the Cancer Center. 
19th Annual Jerome I. Kleinerman, MD Lecture in Pulmonary Pathobiology
May 3, 4p | WRB Auditorium

The Department of Pathology will be hosting The 19th Annual Jerome I. Kleinerman, MD Lecture in Pulmonary Pathobiology on Friday, May 3, 2019 at 4 pm in the Wolstein Research Building Auditorium.

Philip T. Cagle, MD, professor of pathology at 
the Weill  Medical School of Cornell University and S. Donald Greenberg Chair and Director of Pulmonary Pathology at Houston Methodist Hospital in Houston, TX, will be presenting, "Approach to the Lung Cancer Biopsy for Molecular Testing in the Context of the New Guidelines".

A wine reception will be held in the WRB lobby immediately following the lecture. All are welcome to attend.
Innovators in Biomedical Engineering Speaker Series
May 17, 11a | Cleveland Clinic NE1-205

On behalf of Aaron Fleischman, PhD, you are invited to attend the Innovators in Biomedical Engineering Speaker Series on Friday, May 17, 2019 at 11 am.

Herbert Levine, PhD, professor of physics and bioengineering at  Northeastern University,
will present, "What is Epithelial-Mesenchymal Plasticity and Why is it Important for Metastasis?" Previously at Rice University, Dr. Levine co-directed an NSF Physics Frontier Center on applying theoretical and computational methods to living systems. He received his bachelor's degree from MIT and PhD from Princeton, both in theoretical physics and was on the faculty of UC San Diego for 25 years before moving to Rice in 2012 and Northeastern in 2019. His research interests into living systems span a wide variety of topics ranging from computational models of cell motility, pattern formation in microbial colonies, Darwinian evolution in microorganisms, and one the past few years, cancer progression.
Race for the Place 2019
June 2 | Beachwood Place

Celebrating 20 years of serving our community, The Gathering Place is hosting its annual "Race for the Place"  5K and 1-mile run/walk at Beachwood Place on National Cancer Survivors Day, Sunday, June 2.  Proceeds from Race for the Place help support their free programs and services.

The Gathering Place is a caring community that supports, educates and empowers individuals and families currently coping with the impact of cancer in their lives through programs and services provided free of chargeJoin Team Case CCC>
ASCO Review
June 26 | InterContinental Hotel
The ASCO Review will be held Wednesday, June 26, 2019 at the InterContinental Hotel & Bank of America Conference Center in Cleveland, OH to present highlights of the national meeting. The course will provide practicing  hematologists, medical oncologists, radiation oncologists and oncology nurses with current data and information that was presented at the meeting.

The Cleveland Clinic Foundation Center for Continuing Education designates this live activity for a maximum of 6.5  AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Seating is limited! The deadline for registration is 5:00 pm EST, Monday, June 24, 2019. The course includes syllabus, continental breakfast, breaks and lunch. Register now>
NCCN Policy Summit: The State of Cancer Care in America: The Impact of State Policy on Access to High-Quality Cancer Care
June 17 | Washington, DC

The NCCN will host a Policy Summit: 
NCCN logo
The State of Cancer Care in America: The Impact of State Policy on Access to High-Quality Cancer Care on June 27, 2019 in Washington, DC at the National Press Club.

The summit will explore the increasing role of state authorities in health policy decision-making and implications for patient access to high quality cancer care. Major themes of the summit will include the current state regulatory environment governing insurance marketplaces and benefit design, variability across federal and state-level health care coverage landscapes, and best practices for policy makers, providers, and patient advocates to protect patient access to high quality cancer care within shifting legislative and regulatory environments. Register now>
FUNDING OPPORTUNITIES
Brain Research Foundation Scientific Innovation Award 2020
Internal Deadline: April 26, 2019


The Brain Research Foundation has invited eligible US institutions to nominate one senior faculty member to submit a Letter of Intent for the Scientific Innovations Award (SIA). SIA provides funding for innovative science in both basic and clinical neuroscience. This funding mechanism is designed to support creative, exploratory, cutting edge research in well-established research laboratories, under the direction of established investigators.

Based on the quality of applications, the Brain Research Foundation anticipates the SIA program will fund a total of $450,000 in grants. Each total award is limited to $150,000 (direct costs) for a two year grant period from the specified dates only.

The objective of the SIA is to support projects that may be too innovative and speculative for traditional funding sources but still have a high likelihood of producing important findings. It is expected that investigations supported by these grants will yield high impact findings and result in major grant applications and significant publications in high impact journals. Review eligibility and application instructions provided by the Office of Research Administration>

AACR-MPM Oncology Charitable Foundation Transformative Cancer Research Grants
LOI Deadline: May 5, 2019

The AACR-MPM Oncology Charitable Foundation AACR logo Transformative Cancer Research Grants are an exciting new funding initiative to stimulate "high-risk, high-reward" research from early- to mid-career investigators. This novel grant mechanism is intended to promote and support creative, paradigm-shifting cancer research that might not be funded through conventional channels. It is expected that these grants will catalyze significant scientific discoveries that will advance our understanding of cancer and have a potentially transformative impact on future clinical practice.

The grants provide $400,000 over a two-year period for expenses related to the research project. View eligibility criteria and application instructions>
IN THE NEWS
Newly Published Study Shows DecisionDx-Melanoma Prognostic Test Accurately Identified Risk for Patients with Melanoma of the Head and Neck
AP News - Feb 7, 2019
"Tumors of the head and neck region can pose clinical challenges for traditional prognostic methods such as the SLN biopsy procedure," said lead author Brian Gastman, MD, Cleveland Clinic surgeon and member of the Case CCC's Hematopoietic and Immune Cancer Biology Program.

Prostate Cancer: To Treat or Not to Treat?
US News - Apr 9, 2019
For men with non-aggressive prostate cancer, active surveillance is a viable option. Eric A. Klein, MD, chairman of the Glickman Urological and Kidney Institute at Cleveland Clinic and member, Case CCC, comments. 
NIH BULLETIN - Notices and Funding Opportunities
Notices
Guidance on Salary Limitation for Grants and Cooperative Agreements FY 2019

Notice of Change to Activity Codes allowed for Administrative Supplement for Research on Bioethical Issues (Admin Supp Clinical Trial Optional) PA-19-217

Notice of Special Interest for Administrative Supplements for Research on Sexual and Gender Minority (SGM) Populations (Admin Supp Clinical Trial Optional)

NHLBI Limitations on Clinical Trial Applications Submitted to the NIH Parent (R01 Clinical Trial Required) Funding Opportunity Announcement (FOA)Requests for Applications

Notice of Correction to NOT-RM-19-001 Request for Information (RFI): Institutional Accountability to Promote Inclusive Excellence

Requests for Applications
Limited Competition: Interdisciplinary Complementary and Integrative Health Clinical Research Training (T90/R90 Independent Clinical Trial Not Allowed)(RFA-AT-19-010)
Deadlines: June 26, 2019, January 24, 2020

HEAL Initiative: Early Phase Pain Investigation Clinical Network - Specialized Clinical Centers (U24 Clinical Trial Not Allowed)(RFA-NS-19-036)
Deadline: June 3, 2019
IN THIS ISSUE
EVENTSevents
Fri, Apr 19
Research ShowCASE

*No Cancer Center Seminar Series; Series will resume Apr 26*

Nutrition and Center for Proteomics & Bioinformatics
Cynthia Ogden, PhD
Epidemiologist and Analysis Branch Chief
National Health and Nutrition Examination Survey (NHANES) Division
National Center for Health Statistics
Center for Disease Control and Prevention
"The Epidemiology of Obesity"
12p SOM BRB 105
Mon, April 22
Wolstein Research Building Faculty Meetings with Dr. Stan Gerson
12 WRB 3-136

Genomic Medicine Institute
Ignacio "Nacho" Mata, PhD Assistant Staff, Genomic Medicine Institute, Cleveland Clinic 
"Beyond Euro-centric medical research in Parkinson's disease: the LARGE-PD consortium"
12p NE1-205 
Tues, April 23
Cancer Imaging Monthly Meeting
Anirban Sen Gupta, PhD
Professor, Biomedical Engineering
CWRU
1:30p CA5-120
Thurs, April 25
Developmental Therapeutics Journal Club
9a N E 6-218

Keri Lab Bake Sale for VeloSano
11a-2p BRB Lobby

Molecular Biology and Microbiology Seminar
Fengchun Ye
Karn Lab
CWRU
1p SOM W203

Prostate Cancer Working Group Seminar and Journal Club
Jonathan Shoag, MD
Urologic Oncology Fellow
Cornell University
"Repurposing Drugs for Prostatic Disease: Using clinical data to identify drugs with activity against the prostate"
3p NE1-206
Fri, April 26
Taussig Cancer Institute Grand Rounds
8a CA5-120

Cancer Center Seminar Series
Shaun Stauffer, PhD
Director, Center for Therapeutics Discovery
Cleveland Clinic 
Member, Developmental Therapeutics Program
Case Comprehensive Cancer Center
" Using Structure-Based Design to Target Protein-Protein Interactions within the Mixed-Lineage Leukemia (MLL)-COMPASS Complex for Cancer Therapy"
12p WRB Auditorium

GvHD National Symposium
Cleveland Airport Marriott
Mon, April 29
Genomic Medicine Institute
Ignacio "Nacho" Mata, PhD
Assistant Staff
Genomic Medicine Institute
"Beyond Euro-centric Medical Research in Parkinson's Disease: the LARGE-PD Consortium"
12p NE1-205

Cancer Center Research Chalk Talk
Satish Viswanath, PhD
Assistant Professor, Department of Biomedical Engineering, School of Medicine, Case School of Engineering
Assistant Professor, Department of Radiology, School of Medicine
Member, Cancer Imaging Program,
Case Comprehensive Cancer Center
1p WRB 3-136
Weds, May 1
Cancer Center Scientific Series
Research Innovation Fund
John Wang, PhD
Eckhard Jankowsky, PhD Reshmi Parameswaran, PhD 
Hung-Ying Kao, PhD
Sichun Yang, PhD
8:30a Breakfast, WRB 1-422D 
9a Presentations, WRB Auditorium
Thurs, May 2
Developmental Therapeutics Journal Club
9a NE6-218

Molecular Biology and Microbiology Virology Journal Club
1p SOM W203

2019 Great Lakes Breast Cancer Research Symposium
Columbus, OH
Details
Fri, May 3
Taussig Cancer Institute Grand Rounds
8a CA5-120

*No Cancer Center Seminar Series*

2019 Great Lakes Breast Cancer Research Symposium
Columbus, OH
Details

$5 Ice Cream Sundae Bar VeloSano Fundraiser for Team Case CCC
1-3p BRB Lobby

19th Annual Jerome I. Kleinerman, MD Lecture in Pulmonary Pathobiology
Philip T. Cagle, MD
Professor of Pathology
Weill Medical School of Cornell University
S. Donald Greenberg Chair and Director, Pulmonary Pathology 
Houston Methodist Hospital
" Approach to the Lung Cancer Biopsy for Molecular Testing in the Context of the New Guidelines"
4p WRB Auditorium
ADDITIONAL UPCOMING SYMPOSIUMS & EVENTS

prev-funding
PREVIOUSLY ANNOUNCED OPPORTUNITIES

Deadline: Open

Deadline: Open

Deadline: Open
Case Comprehensive Cancer Center