April 2, 2021
Member/Center Highlights
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American Association for Cancer Research Virtual Annual Meeting Part I: Highlights from the Case CCC
AACR
The 2021 American Association for Cancer Research (AACR) Annual Meeting is taking place virtually in two parts. The AACR Virtual Annual Meeting Part I will be held April 10-15 and Part II will be held May 17-21. The AACR Annual Meeting program covers the latest discoveries across the spectrum of cancer research—from population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy—and highlights the work of the best minds in research and medicine from institutions all over the world.
The Case Comprehensive Cancer Center (Case CCC) has compiled lists of presentations, posters and more from Cleveland-based institutions and wish the best of luck to all presenters! We encourage you to sign up for the meeting and block time to hear some of the exciting research presentations and support your colleagues.
Sharifi honored with AACR achievement award for discoveries in cancer research
The Case Comprehensive Cancer Center extends congratulations to Cleveland Clinic's Nima Sharifi, MD, as he has been selected as the 2021 recipient of the American Association for Cancer Research (AACR) Waun Ki Hong Award for Outstanding Achievement in Translational and Clinical Cancer Research.

In the award announcement, AACR highlights that Dr. Sharifi "has made significant contributions to cancer research through his focus on the role of androgen synthesis in advanced castration-resistant prostate cancers." He was selected for his work into how a genetic variant enables prostate cancer cells to evade first-line treatment and leads to aggressive disease.

Dr. Sharifi is director of the Center for Genitourinary Malignancies Research at Lerner Research Institute and the Kendrick Family Endowed Chair for Prostate Cancer Research at Cleveland Clinic. He also leads the Case Comprehensive Cancer Center's GU Malignancies Program and is a professor in the Department of Molecular Medicine. He will present a featured award lecture during Part II of the AACR's 2021 Virtual Annual Meeting in May.
Rodeo Therapeutics Corp. sold to Amgen Inc.
From The Daily: Drug-development startup Rodeo Therapeutics Corp., founded by two leading researchers from Case Western Reserve University School of Medicine and a third scientific partner, has been sold to Amgen Inc., a publicly-traded international biopharmaceutical company. Under terms of the agreement, Amgen, based in Thousand Oaks, California, will acquire all outstanding shares of Rodeo for $55 million, plus "future contingent milestone payments potentially worth up to an additional $666 million in cash," the companies announced Wednesday.

The company was created based on discoveries published in the peer-reviewed journal Science by three scientific founders: Sanford Markowitz, MD, PhD and Stan Gerson, MD, both of Case Western Reserve, and Joseph Ready, of the University of Texas Southwestern.
Dr. Lee on patient and caregiver familiarity with complementary and integrative therapies
Richard T. Lee, MD, Director of Supportive & Integrative Oncology at University Hospitals Seidman Cancer Center and the Helen Moss Foundation - Schoff Family Professor of Integrative Oncology at Case Western Reserve University recently spoke with Oncology Tube about a single-institution study published in JCO Oncology Practice regarding patient and caregiver familiarity with available complementary and integrative medicine services.
Mt. Sinai Health Care Foundation awards $1M grant to Case Western Reserve University School of Medicine
From The Daily: The Mt. Sinai Health Care Foundation—continuing Mt. Sinai Medical Center’s century-old tradition of caring for Northeast Ohio—has expanded its commitment to the region through a $1 million challenge grant to Case Western Reserve University School of Medicine. With this grant, the Mt. Sinai Health Care Foundation has provided over $31 million in lifetime support for Case Western Reserve.

The grant will benefit the Dean’s Catalytic Fund, designed to provide resources for the school’s leader to invest in new opportunities to advance medicine, such as emergency student scholarship support, bridge funding to advance promising early-stage research, and recruitment and retention of exceptional faculty. In this instance, Interim Dean Stan Gerson, MD will use Mt. Sinai’s support to inspire additional philanthropic commitments for recruitment of the next chair of the school’s department of pharmacology.
Open roles at the Case Comprehensive Cancer Center
Join our team! The Case Comprehensive Cancer Center (Case CCC) is currently seeking qualified candidates for the following staff roles:


The Gastrointestinal (GI) Cancer Genetics Program at The Case Comprehensive Cancer Center, with affiliates University Hospitals Cleveland Medical Center and Cleveland Clinic, also invites applications for tenure track/tenured faculty positions at the level of Assistant, Associate or Full Professor.

Applications are also welcomed for a faculty position at the level of Assistant or Associate with a cancer disparities research agenda that builds upon our efforts to address cancer disparities in our catchment area, with a particular focus on determinants of disparities due to race/ethnicity, socioeconomic circumstance, and/or residence in rural communities. 
What's Coming Up
Mark Your Calendar
Cancer Center Seminar Series
Friday, April 9, 2021, 12p via Zoom
There is no Cancer Center Seminar today, Friday, April 2.

Our series returns on Friday, April 9 with Susan Mazanec, PhD, RN presenting, "Preparing Family Caregivers for their Complex Role: A Call to Action for Researchers and Clinicians" on behalf of the Cancer Prevention Control & Population Research Program at noon via Zoom.

Dr. Mazanec is an assistant professor at the Frances Payne Bolton School of Nursing at Case Western Reserve University and a member of the Case CCC's Cancer Prevention Control & Population Research Program.
Cancer Center Seminar Series
Friday, April 16, 2021, 12p via Zoom
On Friday, April 16, Mikhail Shapiro, PhD, will present, "Talking to Cells: Biomolecular Engineering for Non-Invasive Imaging and Control of Cellular Function" on behalf of the Cancer Imaging Program.

Dr. Shapiro is Professor of Chemical Engineering and Investigator at Heritage Medical Research Institute, California Institute of Technology.
Clinical Research Retreat
May 5, 2021, 5-7p | Virtual
Registration is now open for the Spring Clinical Research Retreat! This retreat will focus on cancer imaging in clinical trials.

Anant Madabhushi, PhD will present, "Artificial Intelligence in Radiology: Decision Support tools for the Oncologist" and Nikhil Ramaiya, MD will present, "Role of Imaging in Cancer Clinical Trials and Beyond" during the retreat.
Save the Date! Annual Scientific Retreat
July 22-23, 2021 | Virtual
The 2021 Annual Scientific Retreat for members and trainees is scheduled for July 22-23!

As you may know, this is one of the few times a year our entire center is able to enjoy the company of one another and collaborate.

Registration information, agenda and retreat logistics will be posted in this weekly newsletter and distributed via email to members closer to the retreat.
VeloSano 8 Bike to Cure Weekend
September 10-12, 2021

We are looking ahead with optimism to VeloSano 8 (2021), with a goal of providing opportunities to reunite our VeloSano community in a variety of safe and meaningful ways!

VeloSano is offering options for anyone to participate in any way they are most comfortable - whether riding with us during "Bike to Cure" weekend September 10-12; riding virtually, or by choosing your own activity to participate anytime, anywhere as a Virtual Fundraiser.

The Case Comprehensive Cancer Center, Team Case CCC, will be joining VeloSano again this year and providing complimentary registration and jerseys for its riders. Please contact team captains Caroline El Sanadi or Mary Wright for the registration waiver or code with any questions!
Additional Upcoming Events
AACR
AACR Annual Meeting 2021
April 10-15 and May 17-21, 2021 | Virtual
The AACR Annual Meeting program covers the latest discoveries across the spectrum of cancer research—from population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy—and highlights the work of the best minds in research and medicine from institutions all over the world.

Regular abstracts and the meeting itinerary planner are now available.
Cell-Based Therapies and Tissue Engineering Short Course
May 19-20, 2021
The Skeletal Research Center and the Department of Biology of Case Western Reserve University are pleased to present the twentieth annual short course entitled: “Cell-Based Therapies and Tissue Engineering”, running from May 19 through May 20, 2021.

Registration is now open. The 2021 program is here. To download a flyer, please click here.

Who Should Attend:
This course is intended for graduate students, post-graduate students and health science professionals who are interested in tissue engineering and regenerative medicine approaches with emphasis on translational research principles and protocols used or being modeled for direct clinical use.
2021 Race for the Place
June 6, 2021 | Virtual
Race for the Place in support of The Gathering Place, takes place the first Sunday in June on National Cancer Survivors Day. The Race, a 5K and 1 Mile walk, is a wonderful celebration of cancer survivors and an opportunity to raise money to support the free programs and services provided at The Gathering Place to help children, teens, adults, individuals, families and friends cope while on the cancer journey.

Registration is now open!
NCCN Policy Summit
June 15, 2021 | Virtual
Save the date for the next National Comprehensive Cancer Network (NCCN) policy summit: Defining the "New Normal" - 2021 and the State of Cancer Care in America Following 2020, held virtually Tuesday, June 15, 2021.

NCCN has also scheduled policy summits for September and December of this year. NCCN's recording of their February webinar, "Elevating Cancer Equity: Recommendations to Reduce Racial Disparities in Access to Guideline Adherent Cancer Care" is also now available for public viewing.
AACI Clinical Research Innovation 13th Annual Meeting
July 13-15, 2021 | Virtual
Registration is now open for the 13th Annual AACI CRI Meeting, Adapting Clinical Trials Offices for 2021 and Beyond which will be held virtually July 13-15. The program will provide panel discussions with content experts and breakout sessions for our members and abstract winners and runners-up will be acknowledged in poster sessions.

Abstract Deadline March 15
The CRI Steering Committee is currently soliciting abstracts for the CRI meeting. Abstracts inform meeting attendees about clinical trials office challenges and solutions implemented at AACI cancer centers.

More information, including the program and registration, is now available on the CRI meeting website.
Funding Opportunities
Deadlines vary by award
Available award: $75,000 for one year
LOI Deadline: April 2, 2021

Available award: Up to $120,000 for one year
Deadline: April 16, 2021

Available award: $75,000 for 18 months
Deadline: April 16, 2021

Available award: $180,000 for 18 months
Deadline: April 16, 2021
Available award: $50,000
Deadline: May 15, 2021

Available award: $50,000
Deadline: May 15, 2021

Available award: $25,000 for one year
Applications accepted and awarded on a rolling basis

Proposals are accepted on a rolling basis subject to fund availability

Available award: up to $150,000
Proposals are accepted on a rolling basis
The MDS Foundation, Inc.’s Young Investigator Grant provides an investigator, aged 40 years or less, the opportunity to initiate, continue or complete a project that focuses on either basic or clinical management into the causation, epidemiology, molecular biology, cytogenetics, morphology, prognosis and treatment of the Myelodysplastic Syndromes. The Young Investigator Grant is a two-year research grant in the amount of $100,000, paid in two equal installments to the awardee’s institution.
In The News
Cleveland.com - March 19, 2021
“This adds a layer of precision that even a skilled surgeon can’t have every single time,” said Andrew Sloan, MD, director of the Brain Tumor and Neuro-Oncology Center and the Center for Translational Neuro-Oncology at UH’s Neurological Institute and the Seidman Cancer Center. Dr. Sloan is a member of the Case CCC.
The Scientist - April 1, 2021
A group led by Peter Scacheri, PhD added further evidence that ecDNAs may play a pivotal role in reorganizing the transcriptional control of cancer genomes. Dr. Scacheri is a member of the Case CCC's GI Cancer Genetics Program.
From The NIH
ICYMI: Notice of Changes to NIH Biosketches, Other Support page
To support strong collaboration between Federal research agencies, NIH has made every effort to align the Biographical Sketch (Biosketch), Other Support format page, and Application Form Instructions with the guidance issued by the Office of Science and Technology Policy Joint Committee on the Research Environment. As a result, NIH has released a notice (NOT-OD-21-073) that outlines updates to application forms and instructions to support applicants and recipients' need to provide full transparency and disclosure of all research activities, foreign and domestic. The updated form and instructions will be required for use for applications and Research Performance Progress Reports (RPPRs) submitted for due dates on or after May 25, 2021.
We want to alert you that the changes to the Other Support requirements are significant and much more than simply a change in format. You should review the new template and take some time to read NIH’s FAQ page about the Other Support requirements.

Above all, you should work with your department administrator to update your Other Support documentation now, so that you have it readily available if it is requested by the Cancer Center research administration team for an upcoming progress report or grant proposal. If you have any questions about the new Other Support page and your own department administrator cannot assist, we are happy to help you update or create yours before you’re hit with a deadline! Please reach out to casecccfinance@case.edu and let us know if you have questions or need assistance.
NCI supports NIH Effort to End Structural Racism in Biomedical Research
On March 1, Francis S. Collins, MD, PhD director of the National Institutes of Health, launched a new initiative designed to end structural racism in biomedical research called UNITE. In his statement, Dr. Collins committed NIH to instituting new ways to support diversity, equity, and inclusion, and identifying and dismantling any policies and practices that may harm our workforce and our science.

As part of this initiative NIH has issued a Request for Information seeking input on practical and effective approaches to improve and strengthen racial equity, diversity, and inclusion across all facets of the biomedical research enterprise, both within NIH and the external community, and expand research to eliminate or lessen health disparities and inequities.

On behalf of NIH, we invite you to share your perspective and recommendations as we thoughtfully consider our proactive approach to address racial and health inequities in biomedical research. Comments can be submitted through the submission website and must be received by April 9, 2021.

Please read NCI’s statement, in support of ending structural racism in biomedical research in its entirety.

As we continue to support NIH with the UNITE initiative and further develop our own initiatives to help combat this systemic issue at NCI, we will continue to update you and invite the communities’ input and recommendations.
Weekly NIH Funding Opportunities and Notices
Notices











Funding Opportunities

Deadline(s): June 25, 2021; March 1, 2022; February 1, 2023

Deadline(s): June 25, 2021; March 1, 2022; February 1, 2023

Deadline(s): June 25, 2021; March 1, 2022; February 1, 2023
COVID-19 Funding Opportunities and Notices
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