April 9, 2021
Member/Center Highlights
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American Association for Cancer Research Virtual Annual Meeting Part I: Highlights from the Case CCC
The 2021 American Association for Cancer Research (AACR) Annual Meeting is taking place virtually in two parts. The AACR Virtual Annual Meeting Part I will be held April 10-15 and Part II will be held May 17-21. The AACR Annual Meeting program covers the latest discoveries across the spectrum of cancer research—from population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy—and highlights the work of the best minds in research and medicine from institutions all over the world.
The Case Comprehensive Cancer Center (Case CCC) has compiled lists of presentations, posters and more from Cleveland-based institutions and wish the best of luck to all presenters! We encourage you to sign up for the meeting and block time to hear some of the exciting research presentations and support your colleagues.
Open now: Annual Scientific Retreat Registration, Call for Abstracts
The 2021 Annual Scientific Retreat for members and trainees is scheduled for July 22-23, 2021 and will again be virtual due to university gathering restrictions. This year's retreat features an expanded agenda that mirrors our prior in-person retreats, highlighting research across each of our scientific programs.

Just Announced: TED-style Talk Speakers
Diana Bilimoria
KeyBank Professor and Professor and Chair, Department of Organizational Behavior, Weatherhead School of Management, Case Western Reserve University
Daniel Spratt
Vincent K. Smith Chair in Radiation Oncology,
University Hospitals Seidman Cancer Center
(effective May 1, 2021)
Serpil Erzurum
Chief Research & Academic Officer, Cleveland Clinic
Zihai Li

We are also looking forward to a keynote presentation from Zihai Li, MD, PhD on Friday, July 23. Dr. Li is the founding director of the Pelotonia Institute for Immuno-Oncology and the Klotz Chair in Cancer Research at The Ohio State University.

Call for Abstracts
All students, postdocs and fellows conducting cancer research are invited to submit abstracts for two opportunities to present their research during the retreat: 1) poster presentation and 2) oral presentation. Cancer Center leadership will review abstracts based on the relationship to cancer, novelty, significance of findings and clarity.
Colorectal cancer relapse predicted by immune cell infiltration
From Cleveland Clinic Lerner Research Institute: A research team led by Stephanie Schmit, PhD, MPH, Genomic Medicine Institute, has found that immune cell infiltration of colorectal cancer (CRC) tumors can predict disease relapse in patients who undergo surgery with curative intent. Published in OncoImmunology, the findings may help lead to more targeted post-operative surveillance strategies, which ultimately would improve prognosis for CRC patients at high risk for relapse. Dr. Schmit is a member of the Case Comprehensive Cancer Center's Cancer Prevention, Control & Population Research Program.
Robust immune biomarker predicting survival in HPV-positive head and neck squamous cell carcinoma identified
From University Hospitals: Quintin Pan, PhD and colleagues at University Hospitals (UH) Seidman Cancer Center have identified biomarker immunoglobulin J polypeptide (IGJ), uniquely expressed in plasma cells, predicts early disease-specific mortality among HPV-positive patients with HNSCC. The team published its findings recently in the Journal for ImmunoTherapy of Cancer. Dr. Pan, Deputy Director of Research at UH Seidman Cancer Center and Co-Leader of the Case Comprehensive Cancer Center's Molecular Oncology Program, says he hopes these findings will help inform decisions about which HNSCC patients should be candidates for the treatment de-escalation strategies currently under investigation for HPV-positive patients
TCR repertoire sequencing offered by the Center for Immunotherapy and Precision Immuno-Oncology
We are pleased to announce the upcoming launch of TCR repertoire sequencing as a core service offered by the Discovery Laboratory of the Center for Immunotherapy and Precision Immuno-Oncology (CITI).

The Discovery Lab provides state-of-the-art TCR-beta sequencing right here in Northeast Ohio. These services permits investigators to characterize TCR diversity and identify operative TCR receptors in diseases. In partnership with our Immunomonitoring Lab (IML) we empower investigators to conduct studies that are aimed at dissecting immunity in a wide range of settings.

The services provided by the Discovery Laboratory and Immunomonitoring Lab of CITI are available to scientists, clinicians, and investigators at Cleveland Clinic, Case Comprehensive Cancer Center, Case School of Medicine, UH/Seidman Cancer Center, and industry collaborators. CITI will partner with you to design analytic plans. For information about the services in TCR sequencing lab please click here or send an email to CITIIML@ccf.org.
Open roles at the Case Comprehensive Cancer Center
Join our team! The Case Comprehensive Cancer Center (Case CCC) is currently seeking qualified candidates for the following staff roles:

The Gastrointestinal (GI) Cancer Genetics Program at The Case Comprehensive Cancer Center, with affiliates University Hospitals Cleveland Medical Center and Cleveland Clinic, also invites applications for tenure track/tenured faculty positions at the level of Assistant, Associate or Full Professor.

Applications are also welcomed for a faculty position at the level of Assistant or Associate with a cancer disparities research agenda that builds upon our efforts to address cancer disparities in our catchment area, with a particular focus on determinants of disparities due to race/ethnicity, socioeconomic circumstance, and/or residence in rural communities.
What's Coming Up
Mark Your Calendar
Cancer Center Seminar Series
TODAY, Friday, April 9, 2021, 12p via Zoom
Our series continues today with Susan Mazanec, PhD, RN presenting, "Preparing Family Caregivers for their Complex Role: A Call to Action for Researchers and Clinicians" on behalf of the Cancer Prevention Control & Population Research Program at noon via Zoom.

Dr. Mazanec is an assistant professor at the Frances Payne Bolton School of Nursing at Case Western Reserve University and a member of the Case CCC's Cancer Prevention Control & Population Research Program.
Cancer Center Seminar Series
Friday, April 16, 2021, 12p via Zoom
Next week's Cancer Center Seminar will feature, Mikhail Shapiro, PhD presenting, "Talking to Cells: Biomolecular Engineering for Non-Invasive Imaging and Control of Cellular Function" on behalf of the Cancer Imaging Program.

Dr. Shapiro is Professor of Chemical Engineering and Investigator at Heritage Medical Research Institute, California Institute of Technology.
Clinical Research Retreat
May 5, 2021, 5-7p | Virtual
Registration is now open for the Spring Clinical Research Retreat! This retreat will focus on cancer imaging in clinical trials.

Anant Madabhushi, PhD will present, "Artificial Intelligence in Radiology: Decision Support tools for the Oncologist" and Nikhil Ramaiya, MD will present, "Role of Imaging in Cancer Clinical Trials and Beyond" during the retreat.
Save the Date! Annual Scientific Retreat
July 22-23, 2021 | Virtual
The 2021 Annual Scientific Retreat for members and trainees is scheduled for July 22-23! As you may know, this is one of the few times a year our entire center is able to enjoy the company of one another and collaborate.

Registration for the retreat is now open and trainees are encouraged to submit abstracts by Friday, May 14, 2021.
Register today for VeloSano 8!
Bike to Cure Weekend | September 10-12, 2021

We are looking ahead with optimism to VeloSano 8 (2021), with a goal of providing opportunities to reunite our VeloSano community in a variety of safe and meaningful ways!

VeloSano is offering options for anyone to participate in any way they are most comfortable - whether riding with us during "Bike to Cure" weekend September 10-12; riding virtually, or by choosing your own activity to participate anytime, anywhere as a Virtual Fundraiser.

The Case Comprehensive Cancer Center, Team Case CCC, will be joining VeloSano again this year and providing complimentary registration and jerseys for its riders. Please contact team captains Caroline El Sanadi or Mary Wright for the registration waiver or code with any questions!
Additional Upcoming Events
AACR Annual Meeting 2021
April 10-15 and May 17-21, 2021 | Virtual
The AACR Annual Meeting program covers the latest discoveries across the spectrum of cancer research—from population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy—and highlights the work of the best minds in research and medicine from institutions all over the world.

Regular abstracts and the meeting itinerary planner are now available.
Cell-Based Therapies and Tissue Engineering Short Course
May 19-20, 2021
The Skeletal Research Center and the Department of Biology of Case Western Reserve University are pleased to present the twentieth annual short course entitled: “Cell-Based Therapies and Tissue Engineering”, running from May 19 through May 20, 2021.

Registration is now open. The 2021 program is here. To download a flyer, please click here.

Who Should Attend:
This course is intended for graduate students, post-graduate students and health science professionals who are interested in tissue engineering and regenerative medicine approaches with emphasis on translational research principles and protocols used or being modeled for direct clinical use.
2021 Race for the Place
June 6, 2021 | Virtual
Race for the Place in support of The Gathering Place, takes place the first Sunday in June on National Cancer Survivors Day. The Race, a 5K and 1 Mile walk, is a wonderful celebration of cancer survivors and an opportunity to raise money to support the free programs and services provided at The Gathering Place to help children, teens, adults, individuals, families and friends cope while on the cancer journey.

Registration is now open!
NCCN Policy Summit
June 15, 2021 | Virtual
Save the date for the next National Comprehensive Cancer Network (NCCN) policy summit: Defining the "New Normal" - 2021 and the State of Cancer Care in America Following 2020, held virtually Tuesday, June 15, 2021.

NCCN has also scheduled policy summits for September and December of this year. NCCN's recording of their February webinar, "Elevating Cancer Equity: Recommendations to Reduce Racial Disparities in Access to Guideline Adherent Cancer Care" is also now available for public viewing.
AACI Clinical Research Innovation 13th Annual Meeting
July 13-15, 2021 | Virtual
Registration is now open for the 13th Annual AACI CRI Meeting, Adapting Clinical Trials Offices for 2021 and Beyond which will be held virtually July 13-15. The program will provide panel discussions with content experts and breakout sessions for our members and abstract winners and runners-up will be acknowledged in poster sessions.

Abstract Deadline March 15
The CRI Steering Committee is currently soliciting abstracts for the CRI meeting. Abstracts inform meeting attendees about clinical trials office challenges and solutions implemented at AACI cancer centers.

More information, including the program and registration, is now available on the CRI meeting website.
Funding Opportunities
Deadlines vary by award
Available award: Up to $120,000 for one year
Deadline: April 16, 2021

Available award: $75,000 for 18 months
Deadline: April 16, 2021

Available award: $180,000 for 18 months
Deadline: April 16, 2021
Available award: $50,000
Deadline: May 15, 2021

Available award: $50,000
Deadline: May 15, 2021

Available award: $25,000 for one year
Applications accepted and awarded on a rolling basis

Proposals are accepted on a rolling basis subject to fund availability

Available award: up to $150,000
Proposals are accepted on a rolling basis
The NCCN Oncology Research Program (ORP) is organized to obtain funding to support scientifically meritorious research studies (clinical trials) at NCCN Member Institutions.

There are currently three open requests for proposals:

Submit by Monday, April 19, 2021

Submit LOIs by Monday, May 3, 2021

Submit LOIs by Friday, May 14, 2021
LOI Deadline: April 29, 2021
The Kidney Cancer Association is accepting applications for its 4 Young Investigator Awards (YIAs), 2 Advanced Discovery Awards (ADAs), and (New!) Psychosocial Focus Award.

Three types of grants are available:
  • Two $500,000 Advanced Discovery Awards
  • Four $75,000 Young Investigator Awards
  • One $75,000 Psychosocial Focus Award
In The News
Washington Post - March 30, 2021
Given the many choices available online, Ted Teknos, MD advises consumers to look for thermometers that have been tested “in a rigorous clinical setting with appropriate comparisons to core temperatures.” Dr. Teknos is Deputy Director for University Hospitals at the Case CCC.
Medium - March 31, 2021
Mark Cameron, PhD, associate professor at the School of Medicine, discussed whether society has learned some of the important lessons from the COVID-19 pandemic—particularly given the human tendency to ignore history. Dr. Cameron is a member of the Case CCC.
From The NIH
Weekly NIH Funding Opportunities and Notices
COVID-19 Funding Opportunities and Notices
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