newsletter masthead
August 16, 2019
MEMBER/CENTER HIGHLIGHTS
Remembering Anne Duli
Last month, we notified members of our cancer center
Anne Duli photo
community of the passing of Anne Duli, our friend,  champion and  former Associate Director for Administration and Finance following a long battle with breast cancer.

Anne's life was truly a blessing to all she encountered. A memorial service will be held for Anne tomorrow, Saturday, August 17 at 11 am at Harkness Chapel on the Case Western Reserve University campus. Please join us in celebrating her life full of love, laughter and kindness.
Director Stan Gerson Elected to National Academy of Inventors as Senior Member
The National Academy of Inventors (NAI) has named 54 academic inventors to the Spring 2019 class of NAI Senior
Members, including  Stan Gerson, MD, Director of the Case Comprehensive Cancer Center (Case CCC).

NAI Senior Members are active faculty, scientists 
and  administrators from its Member Institutions who have demonstrated remarkable innovation producing technologies that have brought, or aspire to bring, real impact on the welfare of society. They also have proven success in patents, licensing and comm ercialization.

Gerson, who is also Director of the National Center for Regenerative Medicine at Case Western Reserve University, holds 16 U.S. patents for stem cells and drug discovery, and his research focuses on the relationship between stem cells, DNA and cancer. These discoveries have led to two agents in cancer clinical trials across the nation.

Under Gerson's leadership last year, the National Cancer Institute designated the Case CCC "exceptional," the highest rating possible. The Center, which serves the cancer research and clinical needs of more than four million people in Ohio and beyond, is one of only a handful of 50 such entities to earn an exceptional rating after extensive review of its programs.

"Stan's innovative research and ability to mentor up-and-coming cancer researchers makes him an ideal choice for the NAI Senior Member class," said Pamela B. Davis, MD, PhD, Dean the School of Medicine and Senior Vice President of Medical Affairs at Case Western Reserve University. "His patents will continue to drive us forward in providing new therapies for patients across Cleveland and throughout the world." Read the full release>
Now Available: Case CCC TED Talks at the Annual Scientific Retreat
At the opening of our Annual Scientific Retreat this year, we welcomed three prominent research leaders from each of our affiliated institutions to present engaging TED-style talks.

Leadership 101 | Brian Bolwell, MD
Leadership 101 | Brian Bolwell, MD

Each of these leaders provided remarkable insight and passion for breaking ground in new areas, leading by collaboration and always seeking to better mankind. Recordings of each presentation are now available for viewing at your convenience. We hope you enjoy the presentations as much as we did and look forward to providing similar talks in the future. Watch the talks>
MARK YOUR CALENDARS
Cancer Center Special Seminar
August 22, 3p | WRB 2-136

Please join us on Thursday, August 22 in conference room 2-136 of the Wolstein Research Building for a special seminar from Patricia Thompson, PhD, professor of pathology and Deputy Director of Research, Stony Brook Cancer Center, School of Medicine, Stony Brook University.

Dr. Thompson leads a nationally prominent research program that has focused on the evolution of molecular and cellular changes that occur during the development of colorectal and breast cancer. Her research is concentrated primarily on the discovery and validation of biomarkers that help identify individuals at greatest risk for cancer recurrence, to enable more precise and effective methods to treat cancer patients. She  will present, "Advancing a Path for Cancer Prevention with Clinical Trials of Non-steroidal Anti-inflammatory Drugs."
Next Month: Cancer Center Seminar Series Returns for the 2019-2020 Academic Year
September 13, 12p | WRB Auditorium

Our interdisciplinary seminar series addresses cutting-edge clinical, translational, and basic research topics in cancer. Held weekly on Fridays at 12 pm in the Wolstein Research Building Auditorium, 1-413, attendees are able to interact with our speakers and receive CME credit for the educational activity.

Our series returns Friday, September 13, 2019 with Abhishek Chakraborty, PhD presenting, " Exploiting Dioxygenase Dysfunction to Target Cancer" on behalf of the GU Malignancies Program. Dr. Chakraborty is Assistant Staff, GU Malignancies Research Center at Cleveland Clinic Lerner Research Institute.

We look forward to seeing you each week as the academic year begins again. View the seminar series schedule>
Early Bird Registration: Artificial Intelligence in Oncology Symposium
Oct 24, 2019 | Tinkham Veale University Center
On October 24, the Case Comprehensive Cancer Center will host the inaugural Artificial Intelligence in Oncology Symposium: Advancements in Policy at Case Western Reserve University.

The symposium will bring together experts in AI and machine learning  as well as clinical, industry and federal agency experts in pathology, radiology, oncology and immuno-oncology to speak on research developments, regulatory policy, reimbursement and ethics surrounding AI.

Keynote Presentation
Sohrab Shah, PhD, Chief of Computational  Oncology
at Memorial Sloan Kettering Cancer Center will present a keynote entitled, "Co-evolution of Malignant and Immure Cells in High Grade Serous Ovarian Cancer" at the symposium.

Symposium Highlights:
  • Focused panel discussions
  • Networking opportunities
  • Exhibitions available throughout the day
Be sure to register by August 30, 2019 to secure our discounted early bird registration. A discount for students and trainees who wish to attend is available. We look forward to seeing you in October!  Save your seat>
Early Bird Registration and Call for Abstracts: Innovators in AYA Cancer
Nov 14-15, 2019 | Tinkham Veale University Center
November 14-15, 2019 the Angie Fowler Adolescent and Young Adult (AYA) Cancer Research Initiative of the Case Comprehensive Cancer Center will present  Innovators in AYA Cancer: Driving Science and Policy toward a Brighter Future for Teens and Young Adults with Cancer at Case Western Reserve University.

This symposium will engage physicians, practitioners, advocacy organizations, patients and survivors, their families and caregivers in a conversation about the steps being taken to improve outcomes and address challenges specific to cancer in the AYA population.

Call for Abstracts
Innovators in AYA Cancer will feature a poster session and Rising Star oral presentations. All students, postdocs, residents, fellows and faculty conducting research in AYA cancer are invited to submit abstracts. A committee will review abstracts based on the relationship to AYA cancers, novelty, significance of findings and clarity. Monetary prizes will be awarded. The deadline to submit abstracts is Friday, October 18, 2019.  View abstract submission instructions>

Be sure to register by October 18, 2019 to secure our discounted early bird registration. A discount for students and trainees who wish to attend is available. We look forward to seeing you in November! Save your seat>
Call for Abstracts: 4th Annual Cancer Disparities Symposium
March 6, 2020 | Tinkham Veale University Center

The Case Comprehensive Cancer Center Office of Cancer Disparities Research will present the 4th Annual Cancer Disparities Symposium: Cultivating Science and Community Engagement to Address Cancer Health Disparities on March 6, 2020. 

The symposium  will feature keynote presentations by renowned  disparities  researchers and community leaders, a poster session highlighting academic research and community programs, networking session and an all-attendee forum.

Call for Abstracts
The 4th Annual Cancer Disparities Symposium is a premier event for presenting cutting-edge cancer disparities science and related community programs and services. The Office of Cancer Disparities Research will divide abstracts into two tracks: Scientific Research and Community Programs and Services. Scientific Research abstracts are encouraged from multidisciplinary researchers that are focused on various aspects of health disparities and/or community-focused science. Community programs and service abstracts are encouraged from organizations that provide programs and services that benefit the community. Meritorious abstracts will be selected for oral presentation. Abstracts must be submitted electronically by 5 pm EST on Tuesday, December 3, 2019. Learn more>

Further registration details will be released soon! Sign up for updates>
FEATURED PROFILE: STAFF
April Firstencel,  Protocol Review & Monitoring Committee (PRMC)  Manager, OnCore Administrator
Throughout her working life, April Firstencel has worked in research labs, taught in public schools and the Cleveland Museum of Natural History and has now  been a part of the Case  Comprehensive Cancer Center for nearly 10 years! April initially joined the Case CCC team as the registration/results reporting coordinator for clinicaltrials.gov and the NCI Clinical Trials Reporting Program (CTRP) databases. She now has two vital roles in the Case CCC's Clinical Research Office (CRO): PRMC Manager and OnCore Administrator.

As PRMC Manager, April coordinates and oversees the PRMC, serving as a resource for PRMC chairs, members, reviewers, faculty and staff. She reviews all new study submissions, helps investigators and research staff with the development and submission of documents, determines appropriate levels of review, and coordinates reviewer assignment and PRMC meetings. April also manages and coordinates functions such as accrual monitoring and protocol prioritization efforts, and development and revision of standard operating procedures and protocol templates.

As  OnCore Administrator, April oversees all activities related to the OnCore Clinical Trials Management System, including registration and training of users, quality of database entries, data reporting and troubleshooting. She also works closely with Forte, the company that developed OnCore, on federal regulatory requirements and future enhancements through focus groups and conferences.

In her free time, April enjoys hiking the national parks and creating art from fabric. If you've somehow made it this far without meeting April, you can find her on the second floor of the WRB!
FUNDING OPPORTUNITIES
Open Funding Opportunities at the Case Comprehensive Cancer Center

The Case Comprehensive Cancer Center is 
Case CCC logo
currently  accepting applications for the following additional  funding opportunities. Click each opportunity for award descriptions, funding criteria and application instructions.

Opportunities for Pilot Projects from American Cancer Society IRG Awards
EXTENDED LOI Deadline: Monday, August 26, 2019
2020 Harrington Prize for Innovation in Medicine
Deadline: August 27, 2019

Nominations are now open  for  the 2020 Harrington Prize  for Innovation in Medicine.

Presented by the American Society for Clinical Investigation and the Harrington Discovery Institute at University Hospital, part of The Harrington Project for Discovery & Development, the prize honors a physician-scientist who has moved science forward with notable achievements in innovation, creativity and potential for clinical application.

This annual prize includes:
  • An unrestricted $20,000 honorarium
  • The Harrington Prize Lecture, delivered at the 2020 AAP/ASCI/APSA Joint Meeting
  • Lecture at the 2020 Harrington Discovery Institute Scientific Symposium
  • A personal essay, published in the Journal of Clinical Investigation
Submit nominations through August 27, 2019.
Patient Engagement and Cancer Genome Sequencing (PE-CGS) Network Cancer Moonshot RFAs and Pre-Application Webinars 
Deadline: October 30, 2019

Applications are being accepted for two new funding opportunity announcements (FOAs)  in support of the Patient Cancer Moonshot Logo Engagement and Cancer Genome Sequencing (PE-CGS) Network  of the  Cancer Moonshot . The overall purpose of the PE-CGS Network is to promote and support direct engagement of cancer patients and post-treatment cancer survivors as participants in cancer research. The Network will also use such approaches for rigorous cancer genome sequencing programs addressing important knowledge gaps in the genomic characterizations of tumors.

A pre-application webinar featuring FAQs will take place  September 25, 2019 at 1pm ET. Click here to register.

The two FOAs in support of this Network are:
  • Several U2C Research Centers (RFA-CA-19-045) centered on addressing unique research knowledge gaps in the genomic characterizations of tumors.
  • One U24 Coordinating Center ( RFA-CA-19-046), which will facilitate trans-network collaborative activities.
To learn more including details on research interests, eligibility, budget and how to apply, please visit each of the FOA pages included above. Applications are due October 30, 2019, by 5:00 pm.
IN THE NEWS
How quantum-inspired algorithms could help doctors detect cancer earlier
How quantum-inspired algorithms could help
 doctors detect cancer earlier

CWRU's The Daily - July 15, 2019
"Quantum inspired" algorithms led to dramatic improvements in the application of CWRU's pioneering technique, magnetic resonance fingerprinting (MRF), allowing for scans that are 30% more precise in measuring identifiers of disease and produced as much as three times faster than leading existing techniques. CWRU radiology professor and director of MRI research Mark Griswold, PhD explains the advantages of the algorithms. Dr. Griswold is a member of the Case CCC's Cancer Imaging Program.

The Pathologist - August 13, 2019
Anant Madabhushi, PhD is a leader in artificial intelligence and co mputational pathology, but how did his journey begin and how does he balance so many interests?
NIH BULLETIN - Notices and Funding Opportunities
Notices
NHLBI Announces Availability of Frequently Asked Questions (FAQs) for RFA-HL-20-017, "Cardiovascular Developmental Biology Data Resource Center (U01 - Clinical Trial Not Allowed)"

NHLBI Announces Availability of Frequently Asked Questions (FAQs) for RFA-HL-20-015, "Pediatric Cardiac Genomics Consortium (U01 - Clinical Trial Not Allowed)"

Notice of Correction to the Companion Program Announcement Cited in PA-19-118, Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)

Funding Opportunities
Leveraging Cognitive Neuroscience to Improve Assessment of Cancer Treatment-Related Cognitive Impairment (R21 Clinical Trial Optional)(PAR-19-339)
Deadlines: October 9, 2019; June 10, 2020; October 14, 2020; June 9, 2021; October 13, 2021; June 8, 2022

Leveraging Cognitive Neuroscience to Improve Assessment of Cancer Treatment-Related Cognitive Impairment (R01 Clinical Trial Optional)(PAR-19-340)
Deadlines: October 9, 2019; June 10, 2020; October 14, 2020; June 9, 2021; October 13, 2021; June 8, 2022
IN THIS ISSUE
EVENTSevents
Fri, Aug 16
State of Chronic Disease Disparities in the African American Community Conference
8a Beachwood DoubleTree
Sat, Aug 17
State of Chronic Disease Disparities in the African American Community Conference
9a Beachwood DoubleTree

Memorial Service for Anne Duli
11a Harkness Chapel
Mon, Aug 19
WRB Faculty Meeting with Stan Gerson
3:30p WRB
Tues, Aug 20
Cancer Impact Lecture
Babal Jha, PhD, THOR
1p NE1-205
Thurs, Aug 22
Developmental Therapeutics Journal Club
9a NE6-218

5th Annual Cleveland Breast Cancer Summit - Hands-on Workshop
7:30a Cleveland Clinic Lutheran Hospital Castele Learning Center

Molecular Biology and Microbiology Virology Journal Club
1p SOM W203

Cancer Center Special Seminar
Patricia Thompson, PhD
"Advancing a path for Cancer Prevention with Clinical Trials of Non-steroidal Anti-inflammatory Drugs"
3p WRB 2-136
Fri, Aug 23
5th Annual Cleveland Breast Cancer Summit
Details
7a Intercontinental

UH Seidman Cancer Center Grand Rounds
Daniel Petrylak, MD
Professor of Medicine (Medical Oncology) and Urology, Yale Cancer Center
8a Wearn 137
Tues, Aug 27
Cancer Impact Lecture
Yogen  Saunthararajah
1p NE1-205
Thurs, Aug 29
Developmental Therapeutics Journal Club
9a NE6-218

Molecular Biology and Microbiology Virology Journal Club
1p SOM W203
ADDITIONAL UPCOMING SYMPOSIUMS & EVENTS
prev-funding
PREVIOUSLY ANNOUNCED OPPORTUNITIES

Deadline: Open

Deadline: Open

Deadline: Open
Case Comprehensive Cancer Center