Case CCC News - August 9, 2019

August 9, 2019

MEMBER/CENTER HIGHLIGHTS

Team Case CCC Crosses $60,000 Raised for VeloSano 2019

The rides may be over, but our team's fundraising efforts aren't! Currently, Team Case Comprehensive Cancer Center sits in the Top 15 teams for VeloSano 6 fundraising with over $60,000 raised, but we have until October 1 to make contributions to this year's goal. Thank you to all who have contributed thus far and to all of our riders for coming together for the cause. VeloSano photographers and riders captured some awesome shots from the event - check out our favorites in our Facebook photo album!

MARK YOUR CALENDARS

Remembering Anne Duli

Last month, we notified members of our cancer center

community of the passing of Anne Duli, our friend, champion and former Associate Director for Administration and Finance following a long battle with breast cancer.

Anne's life was truly a blessing to all she encountered. A memorial service will be held for Anne on Saturday, August 17 at 11 am at Harkness Chapel on the Case Western Reserve University campus. Please join us in celebrating her life full of love, laughter and kindness.

Cancer Center Special Seminar

August 12, 2p | WRB 3-136

All are welcome to join us on Monday, August 12, 2019 in the Wolstein Research Building conference room, 3-136 at

2pm for a guest seminar featuring Boaz Tirosh, PhD. Dr. Tirosh is the David Eisenberg Chair in Pharmacy at the Institute for Drug Research, School of Pharmacy at The Hebrew University of Jerusalem.

Dr. Boaz will present, "Pharmacological Induction of Selective Endoplasmic Reticulum Retention as a Novel Strategy for Cancer Therapy."

Cancer Center Special Seminar

August 22, 3p | WRB 2-136

Please join us on Thursday, August 22 in conference room 2-136 of the Wolstein Research Building for a special seminar from Patricia Thompson, PhD, professor of pathology and Deputy Director of Research, Stony Brook Cancer Center, School of Medicine, Stony Brook University.

Dr. Thompson leads a nationally prominent research

program that has focused on the evolution of molecular and cellular changes that occur during the development of colorectal and breast cancer. Her research is concentrated primarily on the discovery and validation of biomarkers that help identify individuals at greatest risk for cancer recurrence, to enable more precise and effective methods to treat cancer patients. She will present, "Advancing a Path for Cancer Prevention with Clinical Trials of Non-steroidal Anti-inflammatory Drugs."

Next Month: Cancer Center Seminar Series Returns for the 2019-2020 Academic Year

September 13, 12p | WRB Auditorium

Our interdisciplinary seminar series addresses cutting-edge clinical, translational, and basic research topics in cancer. Held weekly on Fridays at 12 pm in the Wolstein Research Building Auditorium, 1-413, attendees are able to interact with our speakers and receive CME credit for the educational activity.

Our series returns Friday, September 13, 2019 with

Abhishek Chakraborty, PhD presenting on behalf of the GU Malignancies Program. Dr. Chakraborty is Assistant Staff, GU Malignancies Research Center at Cleveland Clinic Lerner Research Institute.

We look forward to seeing you each week as the academic year begins again. View the seminar series schedule>

7th Annual Genetics Education Symposium: Neurogenetics Across the Lifespan

Sept 12, 2019 | InterContinental Cleveland

Join the Genomic Medicine Institute on Thursday, September 12, 2019 for an engaging day that will meld cutting-edge research with advances in the diagnosis, management and treatment of genetic neurological conditions.

Neil Friedman, MBChB, staff physician and former director of the Center for Pediatric Neurosciences, will deliver the morning keynote address on spinal muscular atrophy. Other topics include autism, Alzheimer disease, psychological assessment in neurogenetic disorders and the ethics of neurogenetic testing.

The day will close with a presentation from Charis Eng, MD, PhD entitled, "Your Genes, Your Wine, Your Health," followed by a wine reception where attendees will have the opportunity to join together with their colleagues. Learn more and register today>

Early Bird Registration: Artificial Intelligence in Oncology Symposium

Oct 24, 2019 | Tinkham Veale University Center

On October 24, the Case Comprehensive Cancer Center will host the inaugural Artificial Intelligence in Oncology Symposium: Advancements in Policy at Case Western Reserve University.

The symposium will bring together experts in AI and machine learning as well as clinical, industry and federal agency experts in pathology, radiology, oncology and immuno-oncology to speak on research developments, regulatory policy, reimbursement and ethics surrounding AI.

Symposium Highlights:

Focused panel discussions
Networking opportunities
Exhibitions available throughout the day

Be sure to register by August 30, 2019 to secure our discounted early bird registration. A discount for students and trainees who wish to attend is available. We look forward to seeing you in October! Save your seat>

Innovators in AYA Cancer: Driving Science and Policy toward a Brighter Future for Teens and Young Adults with Cancer

Nov 14-15, 2019 | Tinkham Veale University Center

Registration will be opening very soon for the Case Comprehensive Cancer Center's AYA Oncology Symposium taking place November 14-15, 2019 at Tinkham Veale University Center at Case Western Reserve University! Sign up to receive updates>

Save the Date: 4th Annual Cancer Disparities Symposium

March 6, 2020 | Tinkham Veale University Center

The Case Comprehensive Cancer Center Office of Cancer Disparities Research will present the 4th Annual Cancer Disparities Symposium: Cultivating Science and Community Engagement to Address Cancer Health Disparities on March 6, 2020. The symposium will feature keynote presentations by renowned disparities researchers and community leaders, a poster session highlighting academic research and community programs, networking session and an all-attendee forum. Further details and a call for abstracts will be released soon! Sign up for updates>

FEATURED PROFILE: STAFF

Amy Egle, Department Assistant, Office of Cancer Disparities Research

In November of last year, Amy Egle joined the Case

Comprehensive Cancer Center administration team as the Department Assistant for the Office of Cancer Disparities Research (OCDR).

Amy oversees and coordinates activities and daily operations

for the OCDR. Her diverse responsibilities include facilitating communications, planning and organizing meetings as well as managing budgets and financial transactions for the office. Amy is also the administrator for the Associate Director for Cancer Disparities Research, Monica Webb Hooper, PhD.

Amy earned a bachelor's degree in music performance from Oberlin College and Conservatory and spent 20 years as a professional violinist and teacher. Prior to joining CWRU, Amy was a project management assistant for a Cleveland-based engineering firm. Visit her on the third floor of the Wolstein Research Building when she's not out representing the Office of Cancer Disparities Research in the community!

FUNDING OPPORTUNITIES

Open Funding Opportunities at the Case Comprehensive Cancer Center

The Case Comprehensive Cancer Center is

currently accepting applications for the following additional funding opportunities. Click each opportunity for award descriptions, funding criteria and application instructions.

Opportunities for Drug Discovery Pilot Projects

Open until 5 projects awarded

Opportunities for Pilot Projects to Utilize the Integrated Microbiome Core

Open until 6 projects awarded

Opportunities for Pilot Projects from American Cancer Society IRG Awards

EXTENDED LOI Deadline: Monday, August 26, 2019

Collaborative Program Grant for Multidisciplinary Teams (RM1)

Internal LOI Deadline: September 17, 2019

This funding opportunity announcement (FOA) is designed to support highly integrated research teams of three to six PD/PIs to address ambitious and challenging research questions that are important for the mission of NIGMS and are beyond the scope of one or two investigators. Collaborative program teams are expected to accomplish goals that require considerable synergy and managed team interactions. Project goals should not be achievable with a collection of individual efforts or projects. Teams are encouraged to consider far-reaching objectives that will produce major advances in their fields.

Review grant details and information regarding application consideration on the Office of Research Administration's website>

Alex's Lemonade Stand Foundation Crazy 8 Initiative

LOI Deadline: October 1, 2019

The Crazy 8 Initiative Award will fund research into innovative and rigorous approaches that directly address the Alex's Lemonade Stand Foundation logo

most intractable issues in pediatric cancer research today. This award is designed to coalesce cross-disciplinary cores of scientists working collaboratively in order to accelerate the pace of new cure discovery. The proposal should address a topic that is responsive to at least one of the four pediatric cancer research themes listed above. Successful applications will address one or more of the eight disciplines that formed the basis of the Crazy 8 initiative: embryonal brain cancers, high grade gliomas, fusion positive sarcomas, fusion negative sarcomas, leukemias, neuroblastoma, big data, catalyzing clinical trials.

Investigations may involve the exploration of a novel scientific hypothesis or the development of new model systems, tools or technologies that have the potential for significant impact on the field of childhood cancer. Collaboration and data sharing are a priority for this research program. We expect successful applications to propose multidisciplinary teams with a very clear plan for collaboration that would empower the study of big ideas that would not be easily addressable otherwise. Childhood cancer research applicants are encouraged to bring new, necessary expertise into the field. Awards will be judged on scientific soundness, significance and the potential for impact on improving the lives of children with cancer.

Letters of intent must be submitted by 11:59 pm ET on October 1, 2019. View the full RFA>

American Lung Association Awards

Deadlines Vary

The American Lung Association recently released the

following funding opportunities:

2020 Lung Cancer Discovery Award

2-year, $200,000 award for highly meritorious research projects with the potential to:

Significantly improve and transform diagnostic and therapeutic paradigms;
Foster innovation, use novel approaches; and/or
Accelerate progress in lung cancer research that improves patient care and helps save lives.
LOI Deadline: Wednesday, October 3, 2019

2020 Innovation Award

2-year, $125,000 award intended to support highly promising investigators with stellar track records of accomplishment, who have the potential to advance the field of lung disease science.

Deadline: Thursday, December 12, 2019

2020 Catalyst Award

2-year, $100,000 mentored award meant to support outstanding investigators on the path to independence for research into the mechanisms of lung disease and general lung biology. Preference is given to projects that are novel; innovative in design/approach; utilize modern technologies; and incorporate a multidisciplinary collaborative training plan.

Deadline: Thursday, December 12, 2019

IN THE NEWS

A year of biomedicine breakthroughs

K AIMRC Innovations - July 28, 2019

"[AI] is already reshaping medicine," says Anant Madabhushi, PhD professor of biomedical engineering at CWRU and director of the university's Center for Computational Imaging and Personalized Diagnostics, pointing to emerging technologies that are awaiting regulatory approval.

Cleveland Clinic, University Hospitals ranked among best in nation

WKYC - July 30, 2019

U.S. News & World Report's annual hospital rankings is giving the Cleveland Clinic and University Hospitals high marks. The clinical partners provide patient care as part of the Case Comprehensive Cancer Center.

Physician leaders call for action to create a new generation of physician-scientists

EurekAlert! - July 31, 2019

Lead author Mukesh K. Jain, MD, Chief Academic Officer at University Hospitals Cleveland Medical Center, Vice Dean of University Hospitals Affairs at Case Western Reserve University School of Medicine, said, "The need to take action is now," as the proportion of U.S. doctors engaged in research has dwindled since the 1980s. Dr. Jain is a member of the Case CCC's Hematopoietic and Immune Cancer Biology Program.