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February 8, 2019
Join Team Case CCC in VeloSano 2019!

The  Case Comprehensive Cancer Center (Case CCC) is honored to once again participate in VeloSano,  a year-round fundraising initiative and "Bike to Cure" weekend to support lifesaving cancer research.

Our continuing goal is to bring sustainable funding to cancer research by enlisting the passion and energy of thousands of people who wish to give back...including YOU! Case CCC's 2018 team was one of the top ten teams in VeloSano this year. This is the center's fifth year participating and in those five years, more than $1,000,000 of VeloSano fundraising totals over the past have come back to the Case CCC to award to researchers as pilot funding for cancer research projects.  

Registration fees and jerseys will be provided by the Case CCC again this year. Contact team captains Caroline El Sanadi or Mary Wright for the registration fee waiver code to sign up!
Madabhushi Co-authors New Breast Cancer Diagnosis Guidelines
On behalf of the College of American Pathologists, Anant Madabhushi, MS, PhD joined other expert researchers to produce a paper that developed new pathology guidelines for accurate testing for breast cancer diagnosis.

Dr. Madabhushi is the F. Alex Nason Professor II
of b iomedical engineering and professor of pathology, radiation oncology, radiology and urology in the School of Medicine at Case Western Reserve University. He is also Director of the Center for Computational Imaging and Personalized Diagnostics within the Case School of Engineering and member of the Case CCC 's Cancer Imaging Program.

The paper, "Quantitative Image Analysis of Human Epidermal Growth Factor Receptor 2 Immunohistochemistry for Breast Cancer" can currently be read through the  Archives of Pathology online .
Plecha Named "Radiologist of the Year" at University Hospitals
Associate Professor of Radiology at Case Western
Photo: @CleMammoEd
Reserve University School of Medicine and Director of Breast Imaging at University Hospitals Cleveland Medical Center, Donna Plecha, MD was honored for her contributions and named, "Radiologist of the Year" for 2018. Dr. Plecha is a member of the Case CCC's Cancer Imaging Program.
Cancer Center Seminar Series: "Cell-matrix adhesion: Molecular basis, signaling and diseases"
Feb 8, 12p | WRB Auditorium

Chuanyue Wu, PhD is today's  guest seminar
speaker. He will be presenting, "Cell-matrix adhesion: Molecular basis, signaling and diseases"  at noon in the WRB Auditorium. Dr. Wu is professor of pathology and Lombardi and Shinozuka Experimental Pathology Research Chair at the University of Pittsburgh School of Medicine. Integrin-mediated cell-matrix adhesion is a fundamental process that controls a variety of processes including cell proliferation, differentiation, migration and survival. Dr. Wu's research focuses on the molecular basis of cell-matrix adhesion, signaling mechanisms and its functions in development and diseases such as cancer. He will discuss some of his team's recent work on the functions of Kindlin-2, a protein that is critically involved in cell-matrix adhesion and signaling.

NEW! The Seminar Series  will  be
available to view via live stream. While we highly encourage you to attend in person to interact with our speakers and receive CME credit, we understand that may not always be possible. Presentations will not be recorded for later viewing, but you may watch the seminar in real time and ask questions via chat. 
Comprehensively Characterize the Tumor Microenvironment in Spatial
Context with Imaging Mass Cytometry
Feb 28, 2p | WRB Auditorium

Have an interest in the ability to simultaneously investigate the expression pattern of multiple proteins within the context of preserved tissue architecture? Attend this seminar to learn more about the Hyperion™ Imaging System.

Tal Varsano, PhD, MScPharm from Fluidigm will discuss the advantages of using heavy metal tagged markers and CyTOF technology to simultaneously visualize the expression of these proteins. This technology can be applied to a broad range of projects in many aspects of cancer research. more>
Reserve Your Spot for the 3rd Annual Cancer Disparities Symposium
Mar 1, 2019 | Tinkham Veale University Center

The Office of Cancer Disparities Research at the  Case Comprehensive Cancer Center   invites you to join the national movement of cancer disparities research, collaboration and programming at the 3rd Annual Cancer Disparities Symposium on March 1, 2019. 

Registration includes access to all symposium sessions, materials, breakfast, lunch, refreshments during breaks and free covered parking.  Reserve your spot today!

Disparities Banner 2019-final

Why you should attend:
  • Network with national thought leaders
  • Learn about cancer disparities research efforts and and funding opportunities
  • Develop academic-community partnerships
Plenary Address
Eliseo J. Pérez-Stable, MD , Director, National Institute on Minority Health and Health Disparities (NIMHD), National Institutes of Health (NIH), will discuss cancer disparities research trends and funding opportunities. 
Distinguished Scientist Keynote
Rick Kittles, PhD, Associate Director of Health Equities at City of Hope, will give a research-focused presentation on cancer disparities research. 

Continuing Research Education Credits (CREC)
Attendees are eligible to receive six (6) continuing research education credits.

NEW! Continuing Education Contact Hours in Health Education (CECH)
Attendees are eligible to receive six (6) advanced-level CECH credits.
GvHD Symposium
April 26, 2019 | Cleveland Airport Marriott

Registration is now open for the 8th Annual Graft vs. Host Disease Symposium to take place Friday, April 26 at the Cleveland Airport Marriott. 

This unique conference, which focuses on cutting edge research and new treatments, consists of two tracks: one designed for physicians and other health care professionals, and one for bone marrow transplant (BMT) survivors, their families and their caregivers.

The Meredith A. Cowden Foundation in collaboration with the Case Comprehensive Cancer Center, University Hospitals Seidman Cancer Center, and Cleveland Clinic Taussig Cancer Institute created the National GvHD Health Symposium in 2010 to raise awareness about Graft vs. Host Disease (GvHD), to promote research to further our understanding of its cause, and to review cutting edge approaches to prevention and treatment.

Over 1,400 people have attended this event, which provides an opportunity for attendees to interact with some of the world's leading authorities on GvHD, a complication that affects over 60% of bone marrow transplant patients. more>
Great Lakes Breast Cancer Symposium
May 2, 2019 | Columbus, OH

Registration is now open for the Great Lakes Breast Cancer Research Symposium (GLBCRS) to take place Thursday, May 2, 2019 at the Grand Event Center in Columbus, OH.  GLBCRS will highlight ongoing basic, translational, clinical and population studies addressing the biological mechanisms, management and prevention of breast cancer. Researchers from participating institutions will share their exciting work with a goal to develop cross-institutional collaborations.

Submit an Abstract
The deadline to submit an abstract for this symposium is Friday, March 1, 2019.
Gena Richmann, MEd, Education Program Manager
After nearly six years in the Department of Biomedical Engineering as an Undergraduate Student Affairs Coordinator, Gena joined the Case Comprehensive Cancer Center in November 2018 to support the Cancer-focused Summer Undergraduate Research (CanSUR) Program. In her role, she develops, directs and manages the CanSUR program.

Gena earned her master of arts in higher education administration from The University of Toledo, where she also holds a bachelor's degree in communications and marketing.

Reach out to Gena for more information on the new CanSUR program, including opportunities to mentor selected scholars or find her on the 3rd floor of the WRB to introduce yourself! more>
Sontag Foundation Distinguished Scientist Awards
Deadline: Mar 13, 2019

The Distinguished Scientist Award (DSA) s eeks 
to provide career and research support to early career scientists who demonstrate outstanding promise for making scientific and medical breakthroughs in the field of brain cancer research.

Recipients of the award are inspired individuals with projects that show potential to generate new knowledge relating to causes, cure or treatment of primary brain tumors/brain cancer. Applicants are carefully considered and selected by The Sontag Foundation and its independent Scientific Advisory Board based on the scientific merit of the proposed project, career trajectory, peer and mentor references and an onsite research facility visit.

The award provides $600,000 in funding over a four-year period. Over that time, recipients also receive additional support from the Foundation through its vast network of scientists in the field primarily through the Foundation's annual Scientific Retreat. more>
DOD/CDMRP FY19 Breast Cancer Research Program Awards
LOI Deadlines Vary: Mar 12-14, 2019

The Department of Defense and its Congressionally CDMRP logo Directed Medical Research Programs (CDMRP) have announced program details and application instructions for the fiscal year 2019 Breast Cancer Research Program (BRCP).

Awards range from $450,000 to $10 million over 4 years.  Letter of intent/preproposal due dates vary by award in the second full week of March with full applications to follow.

Oncology Times - Feb 5, 2019
In his contribution to Oncology Times, Deputy Director for Cleveland Clinic, Brian J. Bolwell, MD writes about the two types of foresight he sees as key characteristics of servant leadership.

How Tennis and Maple Syrup Made Me a Better Doctor
Studies in Empathy Podcast - Jan 15, 2019
Associate professor of medicine and member of the Case CCC's GU Malignancies Program, Timothy Gilligan, MD is interviewed in a new podcast from Cleveland Clinic.
NIH BULLETIN - Notices and Funding Opportunities
Notice of Availability of Competitive Supplements/Revisions for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndromE) Project (Competitive Supplement/Revision Clinical Trial Optional)

Notice of Expiration of Funding Opportunity Announcements PAR-19-168 and PAR-19-169 "Biology of Bladder Cancer (R01, R21 Clinical Trial Optional)"

Program Announcements
Biology of Bladder Cancer (R01 Clinical Trial Optional)(PAR-19-183)
Open Date: May 5, 2019

Biology of Bladder Cancer (R21 Clinical Trial Optional)(PAR-19-184)
Open Date: May 16, 2019

Requests for Applications
Investigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Trial Readiness (R21 Clinical Trial Not Allowed)(RFA-OD-19-015)
Deadline: Mar 14, 2019

Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed)(RFA-OD-19-016)
Deadline: Mar 14, 2019

Clinical Trials Development for Co-Occurring Conditions in Individuals with Down syndrome: Phased Awards for INCLUDE (R61/R33 Clinical Trials Required)(RFA-OD-19-018)
Deadline: Mar 14, 2019
Fri, Feb 8
Taussig Cancer Institute Grand Rounds
8a CA5-120

UH Seidman Cancer Center Grand Rounds
8a Lerner Tower 2060

Cancer Center Seminar Series
Chuanyue Wu, PhD
Professor of Pathology
Lombardi and Shinozuka Experimental Pathology Research Chair
University of Pittsburgh School of Medicine
"Cell-matrix adhesion: Molecular basis, signaling and diseases"
12p WRB Auditorium
Mon, Feb 11
Shared Resources Directors Meeting
12p WRB 1422D

Cancer Center Research Chalk Talk
1p WRB 3-136

Genomic Medicine Institute
Kenan Onel, MD, PhD
Professor, Genetics and Genomics Sciences
Associate Director, Tisch Cancer Institute for Clinical Cancer Genetics and Precision Oncology
Icahn School of Medicine at Mount Sinai
"From genomic questions to clinical answers in cancer"
3p NE1-205
Weds, Feb 13
PRCHN Seminar Series
Jim Spilsbury, Phd
Associate Professor, Department of Population and Quantitative Health Sciences, CWRU
12p BioEnterprise Corporation

Molecular Biology and Microbiology Seminar - Virology Journal Club
Braulio Llorens
12p WRT 206
Thurs, Feb 14
Developmental Therapeutics Journal Club
9a N E 6-218

Molecular Biology and Microbiology Seminar
Angelica Cruz-Lebron
Stephanie Swedik
Levine Lab, CWRU
1p SOM W203

Races for Research Beer Dinner
Proceeds to benefit the Research Institute for Children's Health at Case Western Reserve University
6:30p TownHall Ohio City
Fri, Feb 15
Taussig Cancer Institute Grand Rounds
8a CA5-120

Cancer Center Seminar Series: Olof Pearson Guest Speaker
John C. Byrd, MD
Distinguished University Professor
D. Warren Brown Chair of Leukemia Research
Senior Adviser for Cancer Experimental Therapeutics
The Ohio State University Comprehensive Cancer Center
"Targeted therapies for leukemia"
12p WRB Auditorium
Mon, Feb 18
Genomic Medicine Institute
Stetson Thacker
Eng Lab
"Constitutional PTEN mutation alters alternative splicing in the brain, contributing to an autism phenotype"

Iris Smith, PhD
Eng Lab
"Conformational dynamics and allosteric regulation landscape of germline PTEN mutations associated with autism and cancer"
12p NE1-205

Cancer Center Research Chalk Talk
David Wald
1p WRB 3-136

WRB Faculty Meeting with Stan Gerson
3:30p WRB
Tues, Feb 19
Cancer Drug Discovery and Resistance
Shideng Bao, PhD
Assistant Professor, Stem Cell Biology and Regenerative Medicine, Cleveland Clinic
3p WRB 1422D
Thurs, Feb 21
Developmental Therapeutics Journal Club
9a N E 6-218

Molecular Biology and Microbiology Seminar
Zach Troyer
Tilton Lab
1p SOM W203
Fri, Feb 22
Taussig Cancer Institute Grand Rounds
8a CA5-120

Cancer Center Seminar Series
H. Charles Manning, PhD
Director, Vanderbilt Center for Molecular Probes
Professor, Radiology, Chemistry, Biomedical Engineering, Neurosurgery, and Chemical and Physical Biology
Vanderbilt Ingram Professor of Cancer Research
VU Institute of Imaging Science
"PET tracers to advance precision cancer medicine"
12p WRB Auditorium

Deadline: Open

Deadline: Open

Deadline: Open
Case Comprehensive Cancer Center