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January 11, 2019
Applications Open for Cancer-focused Summer Undergraduate Research (CanSUR) Program
The Cancer-focused Summer Undergraduate Research (CanSUR) program is now accepting applications. 
The new program plans to welcome 32 undergraduates per year for a 10-week experience that will equip scholars for an exciting career in cancer research.

Selected scholars from colleges and universities across the country will be matched with a mentor and participate in a unique, hands-on research experience that will prepare them for the next stage of their careers. Scholars will receive a stipend for the summer; additional housing and travel allowances are available.

Applications will be accepted through February 1, 2019. Learn more about the program and how to apply.
Department of Defense Awards Gupta Nearly $1M to Study Prostate Cancer Drug Resistance
As part of their Idea Award program, the Department of Defence has awarded  Sanjay Gupta, PhD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center a total of $962,000 over three years to investigate drug resistance mechanisms in prostate cancer. The program aims to improve quality of life by decreasing the impact of cancer on active duty service members and their communities.
Gupta will use the award and clinically-approved drugs to develop a safe, efficacious and cost-effective combination therapy for castrate-resistant prostate cancer (CRPC). Gupta is the Carter Kissell Professor and Research Director in the Department of Urology, a research scientist at the Louis Stokes VA Medical Center and a member of the  Case Comprehensive Cancer Center.  more>
Reminder: Athymic Shared Resource Fee Change
The  Athymic Animal and Preclinical Therapeutics Shared Resource has increased prices for the following services effective January 1, 2019:
  • NSG (NOD/SCID/IL2Rgamma): $70
  • NCR nu/nu: $50
  • NOD/SCID: $60
  • Cage day care charge: $1.25
Cancer Center Seminar Series: "Personalized cancer vaccines for hematologic malignancies: A new treatment paradigm"
Jan 11, 12p | WRB Auditorium

The Case Comprehensive Cancer Center's Seminar Series resumes today at 12p in the WRB Auditorium with guest speaker David Avigan, MD presenting "Personalized cancer vaccines for hematologic malignancies: A new treatment paradigm." This seminar is presented by the Hematopoietic and Immune Cancer Biology Program.

Dr. Avigan's research interest lies in the field of tumor immunotherapy and its incorporation into bone  marrow transplantation. His active projects include the
development of dendritic cell tumor fusions  to be used as tumor vaccines in a clinical trial for  patients with
breast cancer now in progression.  He has also been exploring the number of immune reconstitution post-transplant and studying the  impact of cytokine therapy with IL-2 and GM-CSF on this process. He is currently leading a new trial  in the use of post-transplant Her2Neu antibody therapy, assessing its impact on persistent residual  disease. One group is investigating novel approaches to allogeneic transplantation including the use  of non-myeloablative approaches.

Biochemistry Seminar Series presents the Merton F. Utter Distinguished Lecturer:
"Hypoxia, Metabolism, and Tumor Progression"
Jan 31, 4p | BRB 105 Auditorium

The Department of Biochemistry invites you to hear  Celeste Simon, PhD present "Hypoxia, metabolism and tumor progression" on Thursday, January 31 in the BRB Auditorium. Dr. Simon is  Scientific Director of the Abramson Family Cancer Research Institute and Professor in the department of cell and developmental biology at the University of Pennsylvania Perelman School of Medicine. Her laboratory studies cancer cell metabolism, tumor immunology, metastasis, and cellular responses to oxygen deprivation. A reception will follow in the BRB lobby.
Register Today for the 3rd Annual Cancer Disparities Symposium
Mar 1, 2019 | Tinkham Veale University Center
Disparities Banner 2019-final

The Office of Cancer Disparities Research at the  Case Comprehensive Cancer Center  
invites you to attend the 3rd Annual Cancer Disparities Symposium on March 1, 2019. 


Registration is currently OPEN for this symposium. Click here for registration information.

2019 Symposium Highlights
  • Eliseo J. Pérez-Stable, MD, Director, National Institute on Minority Health and Health Disparities (NIMHD), National Institutes of Health (NIH), will discuss cancer disparities research trends and funding opportunities. 
  • Rick Kittles, PhD, Associate Director of Health Equities at City of Hope, will give a research-focused presentation on cancer disparities research. 
  • An entire afternoon session is devoted to research aligned with abstract submissions; this includes oral presentations from selected abstracts, plus a poster session.
  • The audience for this symposium is diverse in background and field, allowing attendees to interact, network, and expand their knowledge and opportunities for collaboration.
Seed Sprint Pilot Grants
Deadline: Jan 18, 2019

The Case CCC encourages responses to the 
Provost's initiative for Seed Sprint grants for new ideas. Academic, co-curricular and administrative/operational proposals are being accepted for these small, short-term grants. Proposals should support the Provost's effort to build new relationships across schools and disciplines.

Ohio Cancer Research Seed Money Grants
Deadline: March 4, 2019

Grants awarded by Ohio Cancer Research (OCR) are Ohio Cancer Research Logo made to support research activities broadly related to cancer and leukemia.  With the support of people all over Ohio, progressive and innovative ideas are given a chance to help in the fight. OCR's seed money projects often give a researcher the preliminary data needed to secure major funding from other sources.

The organization seeks to fund research that will lead to continued support at the national level. Targeted to junior faculty (full professors not eligible to apply), applicants must be independent and within six (6) years of their first independent research position.

The number of grants awarded is dependent upon available funds.  OCR is offering up to $30,000 per year for two years through this competition.

Review grant application details here or call 614.224.1127 for additional information.
CTSC Core Utilization Pilot Grants
Deadline: Feb 1, 2019

The Clinical and Translational Science Collaborative (CTSC) of Case Western Reserve University Core Utilization Pilot Award Program supports investigator use of eligible Core facilities at our partner institutions. This program is designed to collect preliminary data that will lead to extramural sponsored grant funding and/or publications in peer-reviewed journals. Awards up to $10,000 are available.  This program is intended to promote the use of technologies and expertise afforded by identified Core Facilities available at all partner institutions.

Proposals are accepted on a rolling basis and must be submitted by 11:59 PM on the first day of every month (if the first falls on a weekend or holiday, the deadline is extended to the next working day).  more>
Sex differences identified in deadly brain tumors
Science Daily - January 2, 2019
For decades, scientists have recognized that more males get cancer and die of the disease than females. This is true for many types of cancer, including the deadly brain tumor glioblastoma. Now, a team of researchers led by Washington University School of Medicine in St. Louis has identified distinct molecular signatures of glioblastoma in men and women that help explain such underlying disparities in patients' response to treatment and survival. Cleveland Clinic researcher Justin Lathia, PhD and CWRU's  Jill Barnholtz-Sloan, both leaders in the Case CCC, contributed to the research.

CWRU's The Daily - January 9, 2019
"The structures of individual receptor pieces were known, but how they fit together was a mystery. Our study identified a novel interface that bridges the two major functional units of the receptor," says Sichun Yang, PhD a senior author on the study and member, Case CCC.
NIH BULLETIN - Notices and Funding Opportunities
Notice of Information: Updates and clarifications of several components of the Challenge competition posted within the Federal Register

NIH Policy for Review and Resubmission of New Investigator R01 Applications

Fri, Jan 11
Taussig Cancer Institute Grand Rounds
8a CA5-120

Cancer Center Seminar Series
David Avigan, MD
Chief, Section of Hematological Malignancies and Bone Marrow Transplantation,  Beth Israel Deaconess Medical Center
Professor of Medicine, Harvard Medical School
"Personalized cancer vaccines for hematologic malignancies: A new treatment paradigm"
12p WRB Auditorium
Mon, Jan 14
Shared Resources Directors' Meeting
12p WRB 1422D
Tues, Jan 15
Cancer Drug Discovery and Resistance
Mei Zhang, PhD
Asst. Professor, Biomedical Engineering, CWRU
3p WRB 1422D
Weds, Jan 16
Molecular Biology and Microbiology Seminar
Virology Journal Club
Frederick Kizito, Karn Lab, CWRU
12p WRT 206
Thurs, Jan 17
Developmental Therapeutics Journal Club
9a N E 6-218

Molecular Biology and Microbiology Seminar
Uri Mbonye, Karn Lab, CWRU
1p SOM W203
Fri, Jan 18
Taussig Cancer Institute Grand Rounds
8a CA5-120

Cancer Center Seminar Series
Kurt Ribisl, PhD
Professor and Chairman, Department of Health Behavior
Gillings School of Global Public Health
University of North Carolina at Chapel Hill
Lineberger Comprehensive Cancer Center
"The demise of cigarettes and the ride of e-cigarettes: Fixing our flawed response"
12p WRB Auditorium
Mon, Jan 21
Case Western Reserve University and Case Comprehensive Cancer Center Closed for Martin Luther King Jr. Day
Tues, Jan 22
Cancer Imaging Monthly Meeting
Susann Brady-Kalnay, PhD
1:30p WRB 1422D
Thurs, Jan 24
Developmental Therapeutics Journal Club
9a N E 6-218

Molecular Biology and Microbiology Seminar
Skowronski Lab, CWRU
1p SOM W203
Fri, Jan 25
Taussig Cancer Institute Grand Rounds
8a CA5-120

Cancer Center Seminar Series
"Iron and GBMs: Genetics, metabolism and sex"
James Connor, PhD
Distinguished Professor of Neurosurgery, Neural and Behavioral Sciences and Pediatrics
Vice Chair of Neurosurgery Research
Director, Center for Aging and Neurodegenerative Diseases
Penn State University
12p WRB Auditorium

Deadline: Open

Deadline: Open

Deadline: Open
Case Comprehensive Cancer Center