A new five-year, $1.8 million award will allow  Zihua Gong, MD, PhD to work to better understand the mechanisms of resistance of PARP inhibitors (PARPi) that induce cell death in BRCA1 and BRCA2-deficient cancer cells associated with breast and ovarian cancer. Assistant staff in the Department of Cancer Biology at Lerner Research Institute, assistant professor of molecular medicine at CWRU and member of the Case CCC's Molecular Oncology Program, Gong and his team will continue to investigate protein regulations that mediate cancer cell's sensitivity to PARPi. more>

The Biden Cancer Initiative has outlined its priorities for 2019 and will focus on creating action through its working groups: Clinical Trial Design and Enrollment, Data Sharing, Data Standards, Patient Navigation, Prevention and Access to Care. Below is a video from the Initiative that features key experts - including Case CCC director Dr. Stan Gerson who is a member of the Data Sharing Working Group - and reminds us of the importance of creating a more cohesive, comprehensive and timely approach to cancer prevention, detection, diagnosis, research, and care. As Dr. Gerson says in the video, "Vice President Biden realizes he's not asking us to discover more faster. He's asking us to use our information better."  If you have comments and suggestions on how we can achieve this, especially in data sharing, please send along to Dr. Gerson at  [email protected] . 

Ending cancer as we know it

NCI's 2019 Plans: A conversation with the director

Jan 25, 12p | Your smartphone or computer

Join the National Cancer Institute for a live social media event with NCI Director Ned Sharpless, MD discussing NCI's budget and plans for Fiscal Year 2019 with Elizabeth Jaffee, MD, National Cancer Advisory Board Chair, and Dafna Bar-Sagi, PhD, Board of Scientific Advisors Chair.

Jan 25, 12p | WRB Auditorium

Today's seminar features  guest speaker 

James Connor, PhD  presenting  "Iron and GBMs: Genetics, metabolism and sex. " Dr. Connor is visiting from Penn State University where he is Distinguished Professor of neurosurgery, neural and behavioral sciences and pediatrics. He is also Vice Chair of Neurosurgery Research and Director for the Center for Aging and Neurodegenerative Diseases. Dr. Connor has a long-standing interest in brain iron metabolism. His research group was among the first to demonstrate the importance of iron in brain

development and for its particular role in myelination.

Click here for a list of upcoming seminars.

The Steven G. AYA Cancer Research Fund is hosting their 10th annual "Take A Bite Out of AYA Cancer" fundraiser on Saturday, January 26, 2019.  In honor of the anniversary, all attendees will be entered to win an iPad! The fund fuels AYA cancer research here in NE Ohio, wellness and social support programs, as well as advocacy and education.

What: Dinner, beer, wine, dancing, & raffles!

When: 7-11:30p

Where: St. Demetrios Cultural Center, 22909 Center Ridge Road, Rocky River, OH 44116

Tickets: $45,  click here to purchase.

The Department of Biochemistry invites you to hear  Celeste Simon, PhD present "Hypoxia, metabolism and tumor progression" on Thursday, January 31 in the BRB Auditorium. Dr. Simon is  Scientific Director of the Abramson Family Cancer Research Institute and Professor in the department of cell and developmental biology at the University of Pennsylvania Perelman School of Medicine. Her laboratory studies cancer cell metabolism, tumor immunology, metastasis, and cellular responses to oxygen deprivation. A reception will follow in the BRB lobby.

Mar 1, 2019 | Tinkham Veale University Center

Molly Gallogly, MD, PhD

Dr. Gallogly is a Paul Calabresi Scholar in the Case Comprehensive Cancer Center 's Clinical Oncology Research Career Development Program (CORP).  Her research project investigates the efficacy and mechanisms of two cellular therapies (extracorporeal photopheresis and mesenchymal stem cell infusion) for the treatment of steroid-refractory and high-risk graft vs. host disease. Dr. Gallogly is a member of the Hematopoietic and Immune Cancer Biology Program of the Case CCC, and Assistant Professor in the Division of Hematology and Oncology at CWRU School of Medicine.