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July 12, 2019
MESSAGE FROM THE DIRECTOR
Dr. Stan Gerson Stan Gerson, MD
Director, Case Comprehensive Cancer Center
Can't Miss Case CCC TED Talks on July 25
The time has come once again for us to come together as a center at our Annual Scientific Retreat in less than two weeks. Members, fellows, post-docs and trainees have the opportunity to enjoy each other's company, hear updates from leadership, discuss research findings across the spectrum from colleagues and participate in program-specific breakout sessions.
 
New this year, we have opened a portion of our retreat to the community with engaging TED-style talks from three prominent researcher leaders from each of our affiliated institutions. These talks will take place beginning at 5pm on Thursday in the ballroom at Tinkham Veale University Center. While I know you will enjoy each of these talks, I hope you will invite others to take the opportunity to hear from them as well.

Leadership 101
Deputy Director for Cleveland Clinic for the Case CCC, Brian Bolwell, MD will kick off Thursday's talks Bowell, Brian discussing leadership. As Chairman of the Taussig Cancer Institute, his leadership comes from more than just the roles he takes on, but in his commitment to personal development and sharing his experiences in retrospect so that each of us can excel in the research and/or patient care we steward. Bolwell oversees a staff of over 140 physicians, has authored hundreds of articles and abstracts concerning bone marrow transplantation, lymphoma and other hematologic malignancies, and has taken on several roles in editing, reviewing and writing as you'll often see his op-ed features in Oncology Times.

From Healing and Hospitals to Healthy at Home
Peter Pronovost, MD, PhD, FCCM joined University Hospitals in October 2018 as Chief Clinical
Transformation Officer and is  Clinical Professor of anesthesiology and critical care medicine at CWRU. He is a world-renowned champion of patient safety, critical care physician, prolific researcher and thought leader, informing US and global health policy. Pronovost's scientific work leveraging checklists to reduce catheter-related bloodstream infections has saved thousands of lives and earned him high-profile accolades, including being named one of Time magazine's 100 most influential people in the world, receiving a coveted MacArthur Foundation "genius grant" in 2008 and regularly recognized as one of the most influential executives and physician executives in healthcare. The life-saving intervention has been implemented state by state across the US. Today, reducing catheter infections that used to kill as many people as breast or prostate cancer by 80 percent compared to 1999 before the "To Err is Human" report was published.

How Holographic Visualization Will Disrupt Our World
Professor of radiology and biomedical engineering, Mark Griswold, PhD is a member of our Cancer Imaging Program. Griswold received a Medal for Excellence in Health Science Innovation in 2014, chaired the International Society for Magnetic Resonance in Medicine Annual Meeting Program in 2016 and his continued research in   magnetic resonance fingerprinting,  an innovative approach to imaging data, aims to allow quicker and more accurate detection of developing diseases such as cancer, multiple sclerosis or heart trouble. He is frequently called upon as an expert in imaging and his knowledge of Microsoft's HoloLens mixed-reality glasses in use at CWRU to allow students to explore the human body in various health scenarios through life-size transparent holograms in a way that traditional cadavers don't allow.

Thursday's program is open to all and the full retreat agenda is available for those members, fellows, post-docs and trainees registered for the two-day event. We look forward to seeing you there!
MEMBER/CENTER HIGHLIGHTS
Join Team Case CCC for VeloSano 6: Cheer, Volunteer, Donate or Ride!

We're just one week away from our team adorning their colorful jerseys and mounting their bikes at the 6th VeloSano Bike to Cure Weekend! To-date, Team Case CCC has 81 members who are committed to cancer research, prevention, treatment and cures and have  raised $39,808 and counting. We've grown by 6 members and raised $7,434 in the past week!

While it's not too late to commit to riding with us, you can also get involved by volunteering for our cheer station or donating to any rider or the team as a whole to show your support!
Keeping Do-It-Yourself Gene Science Safe: CWRU team will provide policy recommendations
While federal and professional regulatory systems monitor genetic-editing experiments in university and corporate labs, most research conducted outside of these settings lacks formal oversight. 

Now, two Case Western Reserve University faculty members have received a two-year grant to provide regulatory recommendations for gene-editing research conducted in non-traditional settings. The aim of this $160,000 grant from the National Human Genome Research Institute at the National Institutes of Health is to protect the public while encouraging creativity and innovation that could benefit many people.

The grant recipients are Distinguished University Professor and Arthur E. Petersilge Professor of Law, Max Mehlman, and Associate Professor of Genetics and Genome Sciences, Ronald Conlon, MD, a member of the Case Comprehensive Cancer Center. more>
NCCN Annual Conference: Call for Abstracts
The National Comprehensive Cancer Network (NCCN) is now accepting abstracts for consideration to be presented during the NCCN Annual Conference: Improving the Quality, Effectiveness, & Efficiency NCCN logo of Cancer Care™ General Poster Session at the Rosen Shingle Creek in Orlando, Florida on Friday, March 20 and Saturday, March 21, 2020. NCCN welcomes original abstracts from investigators in the general oncology community. Submissions will be accepted from academic institutions, teaching and community hospitals, or industry. Both NCCN and non-NCCN institutions may participate.

Research may fall into the general categories below:
  • Clinical Oncology (all phases)
  • Pre-Clinical Oncology
  • Epidemiology/Risks/Prevention
  • Correlative/Genomic
  • Best Practices in Implementation and Use of Clinical Practice Guidelines
  • Quality Improvement
  • Outcomes and Health Services Research
  • Bioinformatics/Information Technology Sciences
View submission requirements and instructions>
MARK YOUR CALENDARS
Biomedical Innovation and Entrepreneurship Club Networking and Happy Hour
July 17, 2019 | 4-6p
The Biomedical Innovation and Entrepreneurship Club at CWRU meets the third Wednesday of each month. Graduate students, medical students and post-docs are welcome to join this month's discussion and networking happy hour from 4-6pm on July 17th at the CWRU Sears Think[box].

This month's event will feature Bob Sopko, Director of LaunchNET who will share what LaunchNET and Sears Thihnk[box] can do to help with all your entrepreneurial needs. For more information, please contact cvmp@case.edu.
DEPArray(TM) Technology Luncheon Seminar
July 22, 2019 | 12:30p
Discover the DEPArray NxT(TM), a revolutionary system for isolation of single cells or pure cell populations from solid tumor, liquid biopsy and FFPE specimens, even for samples with low cellularity. By resolving sample heterogeneity, it enables the full power of NGS analysis for any sample type, eliminating background noise. View the event invitation>

On Monday, July 22, 2019, Raimo Tanzi, PhD, Chief Market Development Officer of Menarini Silicon Biosystems will visit Case Western Reserve University and present on how DEPArray(TM) Technology Enables Automated, Precise, and Pure Target-Cell Recovery at 1pm in the Wolstein Research Building conference room 3-136. Lunch will begin at 12:30pm. RSVP today>
Case Comprehensive Cancer Center Annual Scientific Retreat
Later this month, our entire center will come together - one of the few times a year we have the opportunity to do so - to collaborate and enjoy each other's company at the center's Annual Scientific Retreat July 25 and 26.

The retreat agenda is now available with TED-style talks from prominent Cleveland research leaders, a reception, keynote, scientific presentations and breakout sessions for programs that you won't want to miss!   Register for retreat today>
Registration Now Open: Artificial Intelligence in Oncology Symposium
Oct 24, 2019 | Tinkham Veale University Center

On October 24, the Case Comprehensive Cancer Center will host the inaugural Artificial Intelligence in Oncology Symposium: Advancements in Policy at Case Western Reserve University.

The symposium will bring together experts in AI and machine learning  as well as clinical, industry and federal agency experts in pathology, radiology, oncology and immuno-oncology to speak on research developments, regulatory policy, reimbursement and ethics surrounding AI.

Symposium Highlights:
  • Focused panel discussions
  • Networking opportunities
  • Exhibitions available throughout the day
Be sure to register by August 30, 2019 to secure our discounted early bird registration. A discounts for students and trainees who wish to attend is available. We look forward to seeing you in October!  Save your seat>
Innovators in AYA Cancer: Driving Science and Policy toward a Brighter Future for Teens and Young Adults with Cancer
Nov 14-15, 2019 | Tinkham Veale University Center
Registration will be opening soon for the Case Comprehensive Cancer Center's AYA Oncology Symposium taking place November 14-15, 2019 at Tinkham Veale University Center at Case Western Reserve University! Sign up to receive updates>
FUNDING OPPORTUNITIES
*NEW* Opportunities for Pilot Projects from American Cancer Society IRG Awards
LOI Deadline: Aug 5, 2019
Full Application Deadline: Aug 19, 2019

The Case Comprehensive Cancer Center, with funds
Case CCC logo
from its American Cancer Society Institutional Research Grant, will provide seed money to foster cancer research by junior faculty who have no current national grant support of their own. Investigators in the CWRU School of Medicine, University Hospitals of Cleveland and Cleveland Clinic Lerner College of Medicine as well as in other schools and colleges affiliated with Case Western Reserve University are eligible. Grants, not to exceed $30,000, will be awarded to investigators who intend to gather preliminary data to be used in seeking future and independently funded programs. A portion of ACS IRG funds is set aside for special interest awards in adolescent and young adult (AYA) cancers.

Award Description
  • Pilot funding for  CANCER-RELATED research with a basic, clinical, prevention and control, behavioral, health services or epidemiological focus.
  • Up to $30,000 award.
  • Applications accepted for general cancer-related projects and for special interest projects in adolescent-and-young-adult cancer research.
Apply to be a CTSC KL2 Scholar!
Deadline: Aug 12, 2019

Qualified candidates are being offered an opportunity to apply to an innovative career  development program whose purpose is to  train clinician investigators
CTSC logo
interested  in  multidisciplinary clinical research. 

The CTSC KL2 program is designed to train the nation's future leaders in clinical and translational research, and is part of the NIH Roadmap aimed at "re-engineering the clinical research enterprise." Scholars embark on a 4-year program of intensive training in multidisciplinary team-based, patient-oriented clinical research, combining an innovative curriculum with mentored research experiences. View eligibility requirements and application instructions>
Building Capacity to Reduce Tobacco Inequities in the South and Midwest
Deadline: Aug 29, 2019

The Robert Wood Johnson Foundation (RWJF) has released a call for proposals to successfully reduce tobacco-related disparities we need to empower leaders from those communities most harmed by tobacco. RWJF seeks to support and engage black community members, persons of lower socioeconomic status, and rural residents in the South and Midwest in order to increase their ability to advocate for stronger, locally or regionally driven tobacco-control and prevention policies and practices. This funding stream will support up to six, two-year projects with the possibility of a second round of funding. The total available funding for this round is $4 million, and individual project budgets should not exceed $1.5 million. The foundation is  interested in and encourages applications that include regranting to support community-based organizations or efforts.

An applicant webinar will be held on Friday, July 17 at 2pm ET. 
View eligibility and selection criteria and application information>
Blood Cancer Discoveries Grant Program
LOI Deadline: Sept 3, 2019

The Leukemia & Lymphoma Society (LLS), the Mark Foundation for Cancer Research (MFCR), and The Paul G. Allen Frontiers Group (PAFG) are proud to announce the Blood Cancer Discoveries Grant Program (BCDG), a new grant program designed to encourage basic research, technological innovation, and informatics pipeline development that can lead to an understanding of blood cancer disease mechanisms, the development of improved methods for detecting and monitoring cancer progression, and the identification of novel therapeutic targets.

The program will support projects for 3 years with up to $750,000, not to exceed $250,000 per year. Letters of intent are due September 3, 2019 by 3pm ET with full applications to follow by invite-only.  View award description and application information>
IN THE NEWS
Oncology Times - June 5, 2019
Case CCC's Deputy Director for Cleveland Clinic, Brian Bolwell, MD asks, "Why are leadership skills relatively uncommon in medicine?" in his latest article in Oncology Times.

University Hospitals Doctor Explains Myeloid Leukemia, Outlook for Carrasco
WCPN ideastream - July 9, 2019
Glenn Forbes speaks with Case CCC member Benjamin Tomlinson, MD about chronic myeloid leukemia and found that the prognosis for the unique leukemia is much better now than 20 years ago.
NIH BULLETIN - Notices and Funding Opportunities
Notices
Notice of New NIH-Designated Data Repository: NHGRIs Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL)

Request for Information (RFI): Guidance on Current Education Curricula for Health Care Professionals Regarding Pain and Opioid Misuse and Use Disorder

Notice of Intent to Publish a Funding Opportunity Announcement for HIV-associated Non-Communicable Diseases Research at Low- and Middle-Income Country Institutions

Funding Opportunities
Maximizing the Scientific Value of Existing Biospecimen Collections: Scientific Opportunities for Exploratory Research (R21 Clinical Trial Not Allowed)
Deadlines: October 8, 2019, August 7, 2020, March 8, 2021
IN THIS ISSUE
EVENTSevents
Fri, July 12
Center of Excellence Retreat in Lymphoid Malignancies Research
Contact Becky Habecker to RSVP at habeckb@ccf.org
8a-4:30p Intercontinental

Cleveland Clinic Cholangiocarcinoma Symposium
Taussig Cancer Center
Details
Tues, July 16
Cancer Impact Lecture
Mohamed Abazeed, MD, PhD
1p NE1-205
Tues, July 17
Biomedical Innovation 
and Entrepreneurship  Club Discussion and networking happy hour
4-6p Sears Think[box]
Thurs, July 18
Developmental Therapeutics Journal Club
9a NE6-218

Molecular Biology and Microbiology Virology Journal Club
1p SOM W203
Fri, July 19
VeloSano Bike To Cure Weekend
Tues, July 23
Cancer Impact Lecture
Xiaorong Gu, PhD
1p NE1-205
Thurs, July 24
Developmental Therapeutics Journal Club
9a NE6-218

Molecular Biology and Microbiology Virology Journal Club
1p SOM W203

Case CCC Annual Scientific Retreat
Details
2:30p Tinkham Veale University Center

Case CCC TED Talks at the Annual Scientific Retreat
Brian Bolwell, MD
Peter Pronovost, MD, PhD, FCCM
Mark Griswold, PhD
5p Tinkham Veale University Center
Fri, July 25
Case CCC Annual Scientific Retreat
7:45a Corporate College East
ADDITIONAL UPCOMING SYMPOSIUMS & EVENTS
prev-funding
PREVIOUSLY ANNOUNCED OPPORTUNITIES

Deadline: Open

Deadline: Open

Deadline: Open
Case Comprehensive Cancer Center