July 2, 2020
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From the Director
Second Annual TED-style Talks on July 23, 2020
Stan Gerson, MD
Director, Case Comprehensive Cancer Center
The time has come once again for us to come together as a center at our Annual Scientific Retreat in just a few weeks. Though it will look different this year in our virtual format, our members, fellows, post-docs and trainees have the opportunity to be enriched by guest speakers, hear updates from Cancer Center leadership and participate in program-specific breakout sessions to help shape future research projects in our abridged retreat.

Again this year, we have opened a portion of our retreat to our broader community with engaging TED-style talks from three prominent leaders of research and advocacy. These talks will take place beginning at 12 pm on Thursday, July 23 and will be broadcast live on the university’s S1 streaming channel simultaneously from a members-only Zoom meeting. These three leaders in their fields will share their insights from decades of experience cultivating community, challenging the status quo, and always seeking to better humankind.

While I know you will enjoy each of these talks, I hope you will invite others to take the opportunity to hear from them as well.
Associate Director for Data Sciences, Case Comprehensive Cancer Center

"GO TEAM! How Team Science Creates Scientific Impact"
Vice Chairman, Department of Pediatric Surgery,
University Hospitals

"Antifragility Initiative"
Founder & CEO, MTN Strategies
Founder & Strategic Advisor, The Gathering Place

"What is your why?"
Member/Center Highlights
Case CCC Annual Scientific Retreat: Developing Team Science
J. Alan Diehl, PhD
Deputy Director and Chief Operating Officer, Case CCC
Big science wins often develop in the background of collaborative teams consisting of laboratories with diverse but complementary research expertise and interests. Among the advantages of developing teams with common scientific goals, is a synergism that arises from unique perspectives. As a result of this synergism, scientific teams make high impact discoveries and develop resources that create a cohesive scientific community.
Koroukian receives American Cancer Society Flatiron Health Real-World Data Impact Award
The Case Comprehensive Cancer Center extends congratulations to Siran Koroukian, PhD, as she was awarded one of three Real-World Data Impact Awards from the American Cancer Society (ACS) and Flatiron Health.

Dr. Koroukian, an associate professor of population and quantitative health sciences at Case Western Reserve University School of Medicine, is already funded by the ACS and will receive additional funding and access to Flatiron's national de-identified oncology datasets. She will, "conduct a retrospective cohort study using the clinical and genomic data to evaluate patterns of genomic testing and targeted therapy in patients with metastatic colorectal cancer to assess the impact of patient and practice characteristics on receipt of these services. These findings will help identify new opportunities to improve the quality and equity of cancer care in patients with advanced colorectal cancer," according to the award announcement .

Dr. Koroukian is director of the Case Comprehensive Cancer Center's Population Cancer Analytics Shared Resource and a member of the Cancer Prevention, Control, & Population Research Program.
Invitation for 5th Annual Cancer Disparities Symposium Planning Committee*
The Case Comprehensive Cancer Center has begun planning for the 5th Annual Cancer Disparities Symposium to be held in March 2021. The Symposium will be organized by Erika Trapl, PhD, Associate Director for Community Outreach and Engagement, and Jennie Cullen, PhD, MPH, Associate Director for Cancer Population Sciences. Dr. Trapl and Dr. Cullen welcome Case CCC members to volunteer to serve on the Symposium Planning Committee. Please fill out this brief form.

*Please note, if you attempted to fill out the form last week but were unable to access it without CWRU credentials, it should be accessible to you now.
Cancer Center Members Shift Research Activities in Response to COVID-19 Pandemic
When the COVID-19 pandemic started, researchers at the Case Comprehensive Cancer Center immediately created plans to shift activities towards combating this deadly disease.
Anthony Berdis
Zheng-Rong Lu
The Future of Regenerative Medicine is Here
The Master of Science in Regenerative Medicine & Entrepreneurship (RGME) at Case Western Reserve University is the first two-year master's level program in Ohio focused on Regenerative Medicine and Entrepreneurship. Students enrolled in the RGME program will have access to cutting-edge clinical and research facilities along with small biotechnology companies within the network of the National Center for Regenerative Medicine (NCRM). Program faculty and guest lecturers are leaders in the field of regenerative medicine and cell-based therapy development from a mix of nationally ranked, medical research powerhouses including Case Western Reserve University, Cleveland Clinic, University Hospitals, MetroHealth Medical Center, Louis Stokes Cleveland VA Medical Center and the Ohio State University.
RGME students are trained in academic, commercial and clinical settings to support cellular manufacturing, biotechnology innovation, legal compliance, financial analysis, venture capital, and business development activities, all while taking advantage of our strengths across the disciplines of regenerative medicine as a whole.
NCCN offering recorded webinars from 2020 Virtual Annual Conference
The National Comprehensive Cancer Network (NCCN) is providing many of their programs as live and/or recorded webinars available free of charge on the NCCN Continuing Education Portal, including a webinar series from the 2020 Virtual Annual Conference.
Case CCC COVID-19 Resource Hub
As the COVID-19 outbreak progresses, the Case Comprehensive Cancer Center (Case CCC) has centralized COVID-19 related news, resources and funding opportunities for our cancer center community. Content is updated regularly.

To have a cancer-focused resource added to the page, please email  cancer@case.edu.
What's Coming Up
Mark Your Calendar
Virtual VeloSano 2020
July 23-24, 2020

VeloSano is more than a fundraising event. It's more than simply a bike ride, and this year, it has gone virtual! VeloSano is a movement with the goal of bringing an entire community together to help one another. The Case Comprehensive Cancer Center (Case CCC) is honored to participate for its sixth year in a row. Together, our team of Case CCC employees and friends are once again joining the movement to raise money for the cause. Team Case CCC is made of passionate individuals who are committed to cancer research, prevention, treatment, and cures! 100% of the money we raise will support lifesaving cancer research in Northeast Ohio's top-tier hospitals and research institutions.

Virtual VeloSano has no fundraising minimums or registration fees and "riders" are able to track their participation in their favorite activity such as biking, hiking, swimming, even gardening any time between now and October 1. VeloSano's signature "Bike to Cure" weekend will still take place virtually, complete with a streaming Kickoff Party and more!

Although we won't be able to unite in person, the need to fund cancer research remains more important than ever. We look forward to seeing our team's virtual participation through photos and videos on social media using hashtag #TeamCaseCCC or tags to @caseccc as we train and rally together remotely. Our continuing goal is to bring sustainable funding to cancer research by enlisting the passion and energy of thousands of people who wish to give back…including YOU! We raised nearly $94,000 last year and our team's participation has collectively brought more than $1,500,000 back to the Case CCC for funding of 31 pilot research projects. We are truly grateful for your commitment to the cause and hope you will join or support our efforts this year!
Don't Forget to Register: Virtual Annual Scientific Retreat
July 23-24, 2020

The Case Comprehensive Cancer Center invites all members and trainees to join us Thursday, July 23 and Friday, July 24, 2020 for our annual scientific retreat! This year's retreat will be held virtually.

Thursday's events are scheduled from 12-2:30pm including TED-style talks from prominent Cleveland researchers and a cancer center update from Director Stan Gerson, MD. All are welcome to attend Thursday's session, though registration is required to receive virtual access.

Friday's member and trainee session will begin at 12:00 pm with a keynote presentation from Timothy Rebbeck, PhD, the Vincent L. Gregory, Jr. Professor of Cancer Prevention at the Harvard T.H. Chan School of Public Health and the Dana-Farber Cancer Institute.

Dr. Rebbeck is founding director of the Zhu Family Center for Global Cancer Prevention at the Harvard TH Chan School of Public Health and leads the Cancer Outreach and Engagement activities for the Dana-Farber Harvard Cancer Center. He will present, "Confronting Cancer Health Disparities: From Cells to Society."

Following a short break, members will then gather in Zoom breakout sessions for their assigned research programs for discussion of initiatives, collaborations and cancer center support of projects through pilots and shared resources.

Please note there will not be a trainee virtual breakout session on Friday, however a bench-to-bedside retreat is being planned for the Spring 2021. More information is forthcoming.

Retreat registration is now open. Please contact Mary Wright at maw143@case.edu) with any questions.
Registration Opening Soon: Artificial Intelligence in Oncology Symposium 2020
October 19-20, 2020

The second annual Artificial Intelligence in Oncology Symposium will bring together experts in AI and machine learning as well as clinical, industry and federal agency experts in pathology, radiology, drug discovery, and ethics and policy to speak on research developments, regulatory policy, reimbursement and ethics surrounding AI in oncology. For the health and safety of all attendees, this year's symposium will take place virtually.

The symposium will feature four focused sessions, with speakers and panel discussions providing unique perspectives on how AI and machine learning are impacting the major areas of radiology, pathology and -omics in the contexts of precision medicine approaches for characterizing tumors and predicting therapeutic response.

Beyond the science, attendees are invited to view a poster session from some of brightest rising stars in the field of AI in oncology.

Geraldine McGinty, MD, MBA, FACR will present the symposium plenary, "Fostering a Strong Ecosystem for AI in Medical Imaging." Dr. McGinty is an internationally recognized expert in imaging economics, Chair of the American College of Radiology Board of Chancellors and Chief Strategy and Contracting Officer at Weill Cornell Medicine in New York City.

Additional keynotes in drug discovery, ethics & policy and pathology will be delivered by Russ Altman, MD, PhD of Stanford University, Aashima Gupta, MS of Google, Vinay Prasad, MD, MPH of the University of California, San Francisco, and Yinyin Yuan, PhD of the Institute of Cancer Research, London. Learn more about AIO 2020 speakers.
Additional Upcoming Events
AACR Virtual Meeting: COVID-19 and Cancer
July 20-22, 2020
This special AACR conference will focus on the presentation of emerging data in basic, clinical, and epidemiologic research related to COVID-19 and cancer. The program will feature a mix of keynote lectures and other invited presentations, short talks from highly rated abstracts, virtual posters, and forums that include panels of experts from various fields. It is anticipated that this must-attend virtual event will attract participants from across the international research community.
12th Annual AACI Clinical Research Innovation (CRI) Meeting
July 7-8, 2020
Registration is now open for the 12th Annual AACI CRI Meeting, Cancer Clinical Research: Focus on the Future.

Registration for the two-day, virtual meeting is free for AACI cancer center members and sustaining members. AACI is working to ensure that the online meeting, scheduled for July 7-8, will still deliver the innovative, quality education that its members have enjoyed at prior CRI annual meetings.

More information, including the program and registration, is now available on the CRI meeting website.
Funding Opportunities
Deadline: August 1, 2020
To improve the discovery and advancement of innovative cancer therapeutics, the Case Comprehensive Cancer Center (Case CCC) has initiated a Drug Discovery Initiative and is providing seed funding toward the development of novel cancer therapeutics. To access funding, investigators must participate in the decennial Case CCC Drug Discovery Census. All therapeutic approaches and modalities are welcome! Projects at all stages are welcome! BE COUNTED! The Census is simple to complete and open to all Case CCC Members. Applications will be accepted until August 1, 2020.

Award Description
  • Awards will be milestone-based and project-specific.
  • Our aim is to select a number of projects for seed funding and to continue to support projects that achieve key milestones.
  • Total funds committed to this RFA are $250,000.
  • Note that projects proposing small-molecule approaches will be considered for additional funding opportunities.
Applications Open January 2021
METAvivor funds research that specifically addresses the mechanistic understanding, diagnosis, and/or treatment of metastatic breast cancer. All individuals with a clinical doctoral degree or with a doctoral degree who are actively engaged in areas of metastatic breast cancer research and treatment are eligible to apply.

METAvivor Research Award
  • Up to 2 years
  • $250,000 award for established investigator

METAvivor Early Career Investigator Award
  • Up to 2 years
  • $100,000 award available to early career applicants

METAvivor funds research focused on treating established breast cancer metastases to improve outcomes for stage IV metastatic breast cancer patients. They do not fund research that that seeks to prevent or diagnose breast cancer metastasis, or that is focused on improving quality of life.
In The News
News 5 Cleveland - June 22, 2020
"We have to perhaps change our behavior, we have to remind people that the virus is still out there and everybody still has a chance to fight this, to be a hero in their community, to block new infections and save people’s lives. We also have to remember that the virus can be controlled and that the chains of transmission can be blocked," said Mark Cameron, PhD, associate professor in the School of Medicine at Case Western Reserve University and member of the Case Comprehensive Cancer Center's Hematopoietic and Immune Cancer Biology Program.
The Daily - July 2, 2020
A team of researchers led by Paul Tesar, PhD have discovered a potential treatment for developed a potential treatment method for Pelizaeus-Merzbacher disease (PMD), a fatal neurological disorder that produces severe movement, motor and cognitive dysfunction in children, resulting from genetic mutations that prevent the body from properly making myelin, the protective insulation around nerve cells. Dr. Tesar is a member of the Case Comprehensive Cancer Center's GI Cancer Genetics and Molecular Oncology Programs.
From The NIH
Weekly NIH Funding Opportunities and Notices

Funding Opportunities

Standard Dates Apply

Standard Dates Apply

Standard Dates Apply

Standard Dates Apply

Deadlines: September 3, 2020; September 3, 2021

Deadline: September 14, 2020
COVID-19 Funding Opportunities and Notices
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