June 11, 2021
Director's Message
Case Comprehensive Cancer Center 2020 Annual Report
Friends,

I am pleased to present Case Comprehensive Cancer Center's 2020 annual report, Passion, Patience & Perseverance: Navigating a Challenging Year. In these pages, you'll read about how our teams collaborated and continued our work as one of the nation's top cancer centers during this difficult time. Please feel free to share these stories with your networks and send us your feedback. We would love to hear from you.
Thank you for your continued support!

Stan Gerson, MD
Director, Case Comprehensive Cancer Center
Member/Center Highlights
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University Hospitals first in Cleveland to offer alternative prostate cancer biopsy technique
From University Hospitals: The University Hospitals (UH) Urology Institute is the first in Northeast Ohio to use a new technique to diagnose prostate cancer. The method allows the urologist to obtain a prostate biopsy with a much lower risk of introducing bacteria than the traditional transrectal ultrasound-guided method which has been used for the past 30 years.

The new technique is called the PrecisionPoint™ Transperineal Access System (PPTAS) in conjunction with MRI-guided fusion technology. It optimizes cancer detection and can be used in an office setting under local anesthesia or with sedation. It is the first FDA-cleared device allowing free-handed transperineal biopsy of the prostate.

Urologic oncologist Jonathan Shoag, MD, is the first physician in Greater Cleveland to use PrecisionPoint. He said, “This new technique may be the future of prostate cancer diagnosis.” Dr. Shoag is involved with a randomized clinical study to yield the highest level of evidence to evaluate the tradeoffs of transperineal MRI-targeted biopsy. Dr. Shoag is a member of the Case Comprehensive Cancer Center's Population and Cancer Prevention Program.
Health Education Campus (HEC) continuing to expand student and faculty presence
The Case Western Reserve University School of Medicine is preparing to get back to the business of education at the Health Education Campus! Our presence at the HEC has been slowly expanding since January, and we will welcome the entering medical school classes for the University Program, the Medical Science Training Program and the Cleveland Clinic Lerner College of Medicine's 5-year physician investigator pathway at the beginning of July. Soon after, the rising second-year medical students will also resume their studies on campus.

Coming back to the HEC reminds us of the value of our educational community, where we can engage in person and develop a sense of connection not possible during the pandemic. We look forward to welcoming students to the HEC and anticipate great energy when we can gather together to learn and talk about medicine. The Sheila and Eric Samson Pavilion will return to pre-pandemic access levels beginning July 1; here's what you need to know.
Graft versus Host Disease (GvHD) Virtual Symposium Series
The Meredith A. Cowden Foundation, in collaboration with the Case Comprehensive Cancer Center, University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute, created the GvHD National Symposium in 2010 to raise awareness about Graft vs. Host Disease (GvHD), to promote research to further our understanding of its cause, and to review cutting edge approaches to prevention and treatment. Due to COVID-19 restrictions and potential risks for symposium participants who may already be immunocompromised, the 2021 in-person meeting has been postponed and a series of short virtual symposia will be held to continue to serve the community.

The first event will take place Friday, July 30 at 10 am EST. This free, 2-hour event will consist of a clinical presentation “Recent Advances in the Management of Acute GvHD” by John Levine, MD from Mount Sinai, followed by a patient-centered Q&A panel hosted by the GvHD planning committee.
Case CCC administration seeking Data/Business System Analyst
We're hiring! The Case Comprehensive Cancer Center (Case CCC) is seeking a Data Coordinator/Analyst to provide ongoing support for the federally mandated reporting requirements of the Cancer Center Support Grant (CCSG) of the Case Comprehensive Cancer Center. This individual will be responsible for a variety of tasks in translating business and operational requirements into SQL-based database reports, standardized operational procedures, and workable IT and administrative solutions. The Coordinator/Analyst will collect, organize, and report on Cancer Center data including, but not limited to, information about Cancer Center members’ grants, publications, events, internal funding, and community outreach. They will also assist in developing better data coordination and management procedures, managing and creating reports for existing databases, and providing recommendations for strategic improvements to the Cancer Center’s data organization.
What's Coming Up
Mark Your Calendar
Register Today for the Annual Scientific Retreat
July 22-23, 2021 | Virtual
The 2021 Annual Scientific Retreat for members and trainees is scheduled for July 22-23! As you may know, this is one of the few times a year our entire center is able to enjoy the company of one another and collaborate.

This year's virtual retreat features an expanded agenda that mirrors our prior in-person retreats, highlighting research across each of our scientific programs.

The retreat will begin Thursday with an address from Director Stan Gerson, MD, followed by TED-style Talks from Diana Bilimoria, PhD, Daniel E. Spratt, MD, and Serpil Erzurum, MD. Registration for the retreat is now open.
Zihai Li
Keynote
Zihai Li, MD, PhD will present the retreat keynote on Friday, July 23. Dr. Li is the founding director of the Pelotonia Institute for Immuno-Oncology and the Klotz Chair in Cancer Research at The Ohio State University.
Register today for VeloSano 8!
Bike to Cure Weekend | September 10-12, 2021
We are looking ahead with optimism to VeloSano 8 with a goal of providing opportunities to reunite our VeloSano community in a variety of safe and meaningful ways!

VeloSano is offering options for anyone to participate in any way they are most comfortable - whether riding with us during "Bike to Cure" weekend September 10-12; riding virtually, or by choosing your own activity to participate anytime, anywhere as a Virtual Fundraiser.

The Case Comprehensive Cancer Center, Team Case CCC, will be joining VeloSano again this year and providing complimentary registration and jerseys for its riders. Please contact team captains Caroline El Sanadi or Mary Wright for the registration waiver or code with any questions!
Save the Date: Great Lakes Breast Cancer Symposium
October 25-26, 2021 | Virtual
Save the date for the Great Lakes Breast Cancer Symposium, to be held virtually October 25-26, 2021!

This annual symposium highlights ongoing basic, translational, clinical and population studies addressing the biological mechanisms, management and prevention of breast cancer. Researchers from participating institutions will share their exciting work with a goal to develop cross-institutional collaborations.

Though this event is happening virtually, attendees will experience the conference using Whova, our official web-based conference app, to view presentations and ask questions in real-time, as well as network with others behind the scenes.
Helen Piwnica Worms
Keynote
Helen Piwnica-Worms, PhD, will deliver a keynote at the symposium. Dr. Piwnica-Worms is Professor, Department of Experimental Radiation Oncology, Division of Radiation Oncology and Senator AM Aiken Jr. Distinguished Chair at University of Texas MD Anderson Cancer Center.

Registration and call for abstracts for this symposium will open June 2021.
Save the Date: 2021 Artificial Intelligence in Oncology Symposium
November 8-9, 2021 | Virtual
The 2021 Artificial Intelligence in Oncology Symposium: Precision Medicine and Cancer Disparities will bring together experts in AI and machine learning as well as clinical, industry and federal agency experts in pathology, radiology, drug discovery, ethics and policy to speak on research developments, and health disparities surrounding AI in oncology.

For the health and safety of all attendees, this year's symposium will again take place virtually. Registration for the symposium is not yet open.
Additional Upcoming Events
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Summer Vitals Lecture Series
June-August, 2021 | Virtual
The Office of Diversity and Inclusive Excellence in the Case Western Reserve University School of Medicine is hosting “2021 Summer Vitals,” a virtual lecture series about health disparities and the effects of COVID-19. Lectures include:

Tuesday, June 29, 7–7:45 am
  • The Asian American and Pacific Islander Experiences of Racism During COVID-19

Wednesday, July 21, 5–5:45 pm
  • The Effects of COVID-19 on Women in the Academy

Wednesday, Aug. 25, 12–12:45 pm
  • Health Disparities in Latinx and COVID-19
Women in Data Science (WiDS) Cleveland
June 30, 2021 | Virtual 1:15-4:45p ET
The Cleveland Institute for Computational Biology (CICB) and the Department of Population and Quantitative Health Sciences (PQHS) are excited to host the first annual Women in Data Science (WiDS) Cleveland event on Wednesday, June 30, from 1:15 pm - 4:45 pm.

The Global Women in Data Science (WiDS) initiative aims to inspire and educate data scientists worldwide, regardless of gender, and to support women in the field.

WiDS Cleveland is an independent event organized by the WiDS Cleveland team as part of the annual WiDS Worldwide conference organized by Stanford University and an estimated 150+ locations worldwide, featuring outstanding women doing work in the field of data science. All genders are invited to attend all WiDS Worldwide conference events.

The inaugural WiDS Cleveland 2021 will be held virtually via the Gather.town platform as a casual gathering providing an opportunity to hear about the latest data science-related research in a number of domains, learning how leading-edge companies are using data science for success, and connecting with potential mentors and collaborators in the field. All are invited to attend.

AACI Clinical Research Innovation 13th Annual Meeting
July 13-15, 2021 | Virtual
Registration is now open for the 13th Annual AACI CRI Meeting, Adapting Clinical Trials Offices for 2021 and Beyond which will be held virtually July 13-15. The program will provide panel discussions with content experts and breakout sessions for our members and abstract winners and runners-up will be acknowledged in poster sessions.

More information, including the program and registration, is now available on the CRI meeting website.
Midwest Melanoma and High Risk Skin Cancer Symposium
July 16, 2021 | Live Stream 8a-1:15p ET
This half day CME accredited symposium is specifically designed to provide those who have skin cancer management interests the latest advances in prevention, surveillance, and local-regional and systemic therapies.

This activity will bring together an audience of medical oncologists, radiation oncologists, surgeons, dermatologists, nurses, and other health care providers to discuss management of these patients.

Click here to view the symposium agenda. Registration includes access to presentations for 3 months after program.
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NCI Drug Development Workshop Series: How to Advance A Therapeutic Candidate from Bench to Bedside
July 23, 2021 - December 10, 2021
This workshop being sponsored by the Developmental Therapeutics Program at the NCI will entail a series of 10 webinar-based lectures held Friday afternoons (12-2:30 pm ET) July 23, 2021 through December 10, 2021. The goal of this workshop is to provide researchers with an interactive setting in which they will gain an understanding of product development considerations for anti-cancer therapeutics, to facilitate successful translation from preclinical to clinical studies.

This workshop is specifically designed for researchers who are interested in learning about key activities that are needed to take their discoveries from the lab to the clinic. Junior faculty and trainees are encouraged to attend.

Workshop topics will encompass key IND-enabling activities and milestones, regulatory considerations, as well as contemporary first-in-human trial design, available NCI translational resources, insights from the private sector for entrepreneurial purposes, and case studies. Each session includes facilitated questions and answers (Q&A) to engage audience in the discussion.

Session recordings will be made available to the public at the registration site. Registration is not required for accessing the recordings. Please note that while you may register for one or multiple sessions, attendance for all sessions is encouraged to gain the maximal learning and benefit.

8th Annual Genetics Education Symposium
September 30, 2021 | Live Stream 8a-4:45p ET
This accredited program, presented by Cleveland Clinic’s Genomic Medicine Institute (GMI) and the Center for Personalized Genetic Healthcare (CPGH), will provide the opportunity to review the latest advances in genetics and genomics. GMI and CPGH will provide state-of-the-art information to healthcare providers treating patients with hereditary cancer syndromes.

Expert Cleveland Clinic and guest faculty will present case- and research-based presentations highlighting the integration of genetics and genomics into clinical practice.

Invited are practitioners and healthcare professionals seeking to learn the latest developments in medical genetics, especially providers in Hematology/Oncology, Genetics, Internal Medicine and Subspecialties, Pediatrics, and Nursing. Trainees and students with an interest in expanding their knowledge of genomic medicine and related topics are also encouraged to attend.

Funding Opportunities
Gabrielle's Angel Foundation for Cancer Research invites the Case Comprehensive Cancer Center to nominate two applicants for their junior faculty grant program. The Case CCC may nominate one researcher who is conducting mainstream or conventional research and one who is conducting complementary or integrative research.

Internal Selection Process:
Investigators should submit Letter of Intent (one page, template available) and an NIH-style biosketch through this InfoReady application form by Friday, July 9, 2021.

Case Comprehensive Cancer Center leadership will review all applicants. Selected nominees will work with their department research administrators and the Case CCC to submit full applications to the sponsor before August 27, 2021.
Conquer Cancer, the ASCO Foundation and Pfizer Global Medical Grants are collaborating to offer a research grant funding opportunity to promote the advancement of scientific knowledge concerning equitable care of metastatic breast cancer patients. This research grant program will employ data-driven frameworks to define and address inequities in the delivery of care and outcomes for patients of color with metastatic breast cancer.
With the generous support from VeloSano Bike to Cure 2020, the Case Comprehensive Cancer Center (Case CCC) is providing seed funding for innovative and impactful proposals that will generate key data for larger, nationally competitive multi-investigator/team grants (MPI R01, P01, U01, SPORE, etc.). The Case CCC has recently undertaken a reorientation of its scientific programs, and this award will provide funds for each of our six scientific programs. Program Leaders will select the award aligned to their program, and therefore will not serve as project PI. Projects must be focused on the establishment or support of a collaborative effort by a team of 2 or more independent investigators from the case Case CCC research program. The goal is to submit a federal team science grant application.
In The News
Spectrum News 1 - June 8, 2021
President and Scientific Director of University Hospitals Seidman Cancer Center, Theodoros Teknos, MD said UH is the only hospital system in the state that has a lab on-site where CAR T therapy products are being generated for clinical trials. Dr. Teknos is Deputy Director for University Hospitals at the Case CCC.
Mirage News - June 9, 2021
The National Center for Regenerative Medicine, a leader in cellular manufacturing and regenerative medicine, formally added The MetroHealth System as an institutional member following a vote by the organization’s board of governors last month.
From The NIH
National Cancer Institute Requests for Information: Enhancing Cancer Health Disparities Research and Diversity and Inclusion in the Cancer Research Workforce
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The National Cancer Institute (NCI) Equity and Inclusion Program seeks actionable recommendations to enhance cancer health disparities research and diversity and inclusion in the cancer research workforce through the following two Requests for Information (RFIs).

Jennifer Cullen, PhD, MPH (jxc1650@case.edu) and Erika Trapl, PhD (erika.trapl@case.edu) are coordinating a response on behalf of the Case Comprehensive Cancer Center, and welcome your feedback and comments.


Weekly NIH Funding Opportunities and Notices
Funding Opportunities

First application due date: July 7, 2021. NCI ESI MERIT Award Extension requests are due during the penultimate award year, either on March 1, July 1, or November 1. 
COVID-19 Funding Opportunities and Notices
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