News and Updates from the Case Comprehensive Cancer Center
March 13, 2020
Member/Center Highlights
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Message from the Associate Director for Cancer Disparities Research
Monica Webb Hooper
Monica Webb Hooper, PhD
"When we talk about health disparities, we have to deal with the real issues." -Yvonka M. Hall, Executive Director, Northeast Ohio Black Health Coalition

On March 6, 2020, over 250 people convened in the state-of-the-art Tinkham Veale University Center on the Case Western Reserve University campus for the 4th Annual Cancer Disparities Symposium “Cultivating Science and Community Engagement to Address Cancer Health Disparities." Cultivation is about promoting, fostering, nourishing, and working to make something better. This exemplifies what has occurred over the past four years in the Case Comprehensive Cancer Center (Case CCC) – our collective efforts to advance health disparities science have cultivated academic efforts to enhance our understanding of cancer-related disparities, and emphasized the importance of community engagement as a key component. 
The presentations from each of our speakers served to educate, motivate, and inspire us all, providing models to carry forward. We welcomed researchers, clinicians, health professionals, community outreach groups, patient advocates, trainees, and key stakeholders from community-based organizations, local government, private foundations, and commercial businesses – across 14 states. We shared ideas and formed new connections. The energy in the room was persistent and engaging – and the concluding panel discussion challenged us to think deeper about both science and community.
Continue reading this message
View symposium photo gallery
COVID-19 (Novel Coronavirus), your research program at CWRU and upcoming events across the Case Comprehensive Cancer Center
As spring break comes to a close today, Case Western Reserve University has moved to remote delivery of education commencing Wednesday, March 18 following class closures Monday and Tuesday (March 16-17) and issued restrictions pertaining to on-campus meetings, gatherings, and conferences. As of this time, other campus operations, including research, will continue.

The Case Comprehensive Cancer Center is working to establish virtual meetings where possible and maintain a current calendar of events as meetings across our partner institutions are postponed, canceled, or made available virtually.

The Office of Research and Technology Management has also asked researchers to be prepared for the impact of the Novel Coronavirus might be on their research in various scenarios.
CWRU Health Updates
Coronavirus and your research program
AI reveals differences in appearance of cancer tissue between racial populations
From The Daily: Scientists at Case Western Reserve University are using Artificial Intelligence (AI) to reveal apparent cellular distinctions between black and white cancer patients, while also exploring potential racial bias in the rapidly developing field of AI.

Their most recent published research asserts that AI analysis of digitized images of cancer tissues reveals critical variations between black and white male prostate cancer patients. The work also suggests the new population-specific information—in addition to image detail on tissue slides also analyzed by computers—could substantially improve care for black patients with prostate cancer.
“On one level, we’re simply trying to understand and answer this question: Are there biological differences in the disease, in the cancer, that are a function of your ethnicity or your race?” said Anant Madabhushi, MS, PhD the F. Alex Nason Professor II of Biomedical Engineering at Case Western Reserve and senior author on a study published March 5 in Clinical Cancer Research, a journal of the American Association for Cancer Research. “In other words, is there something else going on that can’t be explained by other disparities? The answer appears to be, ‘yes.’”
Read more in The Daily
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Join Team Case CCC in VeloSano 2020!
The Case Comprehensive Cancer Center (Case CCC) is honored to make its sixth appearance in VeloSano, a year-round fundraising initiative and "Bike to Cure" weekend to support lifesaving cancer research. Our continuing goal is to bring sustainable funding to cancer research by enlisting the passion and energy of thousands of people who wish to give back... including YOU! We raised nearly $94,000 in 2019 and every dollar goes directly toward cancer research. In our six years of participation, more than $1,000,000 of VeloSano fundraising totals have come back to the Case CCC to award researchers as pilot funding for cancer research projects.
The Case CCC will provide complimentary registration fees and jerseys again this year. Contact team captains Caroline El Sanadi or Mary Wright for the registration fee waiver code to sign up! While registration is complimentary, all riders are responsible for meeting the minimum fundraising commitment associated with the distance they ride. Fundraising can begin as soon as you register to ride and continues through October 1, 2020.

Registration is open now and information about volunteering for our cheer station and supporting our team through sponsorship will be available soon!
Learn more about VeloSano 7 and joining or supporting Team Case CCC
What's Coming Up
Mon, Mar 16
Cancer Center Research Chalk Talk
Sarah Markt, ScD, MPH
1p WRB 3-136

WRB Faculty Meetings with Stan Gerson
3:30p WRB
Tues, Mar 17
Cancer Drug Discovery and Resistance
3p Zoom
Thurs, Mar 19
Molecular Biology and Microbiology Seminar
1p Monitor calendar for event updates
Fri, Mar 20
Cancer Center Seminar Series
Omar Mian, MD, PhD
12p Zoom
Details
Mon, Mar 23
Cancer Center Research Chalk Talk
You-Wei Zhang, PhD
1p WRB 3-136

Thurs, Mar 26
Molecular Biology and Microbiology Seminar
1p Monitor calendar for event updates
Fri, Mar 27
Cancer Center Seminar Series
Stanley Huang, PhD
12p Zoom
Case CCC Calendar
LRI Calendar
Mark Your Calendar
CANCELLED : Cancer Center Seminar Series
March 13, 12p

This week's cancer center seminar has been cancelled due to our guest speaker's institutional travel restrictions.

Our series will resume virtually on Friday, March 20 due to institutional restrictions.

CME credit will still be available for those who attend seminars live via Zoom. If you are unfamiliar with Zoom, click here to view instructions and support topics. Contact Kelsey Kirsch for more information.
View the Seminar Series schedule
Cancer Center Seminar Series
March 20, 12p
Zoom ID 115 070 942


Next week's cancer center seminar will be presented by Omar Mian, MD, PhD.

Dr. Mian is associate staff at Cleveland Clinic Taussig Cancer Institute and assistant professor of medicine, at Case Western Reserve University School of Medicine. He is also a Member of the Case Comprehensive Cancer Center's GU Malignancies Program.

He will present, "Subtype Speciation and Convergent Evolution of Small Cell/Neuroendocrine Carcinoma" on behalf of the GU Malignancies Program.
Core Facilities and Shared Resources Symposium
April 28, 2020
Linsalata Alumni Center, CWRU

Case Western Reserve University will host a campus-wide symposium on core facilities and shared resources on Tuesday, April 28, 2020. This year's symposium, "Stronger Together" will highlight the ways in which our Cores are the foundation for interdisciplinarity and the nexus of team science.

Opening remarks from Provost Ben Vinson III will begin at 8:30 am. This opportunity for networking and discovery will feature:
  • plenary talks from CWRU faculty from various schools/colleges
  • breakout sessions celebrating how our cores create a continuum of discovery across multiple disciplines and providing administrative technical assistance about running a Core
  • poster sessions showing the work our facilities make possible
Register for the core facilities symposium
Call for Abstracts and Registration: Cancer Stem Cell Conference 2020
August 4-6, 2020
Tinkham Veale University Center

The Case Comprehensive Cancer Center and the National Center for Regenerative Medicine invite you to submit an abstract and register for CSC 2020!

Now in its fourth year, CSC 2020 will feature renowned thought leaders in the field of cancer stem cell research. This conference is guaranteed to offer cutting-edge keynote presentations from a variety of niches within the field. Join world-class investigators for this three-day summit and network with scientists and clinicians advancing cancer stem cell research and therapeutic applications. 

The Cancer Stem Cells Conference call for abstracts affords an exciting opportunity to highlight cancer stem cell focused research, providing a forum to showcase basic research, as well as novel technologies and translational therapeutic strategies. Basic science, clinical and translational researchers, as well as trainees, are invited to submit abstracts by 5 pm EST, Friday, May 29, 2020.

Symposia topics include, but are not limited to: developmental biology, immune interaction, microenvironment, cellular metabolism, epigenetic regulation, druggable targets and emerging technologies.
Learn more and register for #CLECSC2020
Save The Date: Great Lakes Breast Cancer Symposium 2020
October 4-6, 2020
Tinkham Veale University Center, CWRU

As host site for the 2020 Great Lakes Breast Cancer Symposium, the Case Comprehensive Cancer Center encourages you to mark your calendar for the symposium taking place October 4-6, 2020.

The symposium highlights ongoing basic, translational, clinical and population studies addressing the biological mechanisms, management and prevention of breast cancer. Researchers from participating institutions will share their exciting work with a goal to develop cross-institutional collaborations.

This year's event features two keynote speakers:
  • Carlos Arteaga, MD, Director of the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center
  • Helen Piwnica-Worms, PhD, Professor of Experimental Radiation Oncology at the University of Texas MD Anderson Cancer Center
Sign up to receive symposium updates
Additional Upcoming Events
POSTPONED: NCCN 2020 Annual Conference
March 20-22, 2020
Orlando, FL

The annual gathering of leading oncology professionals to discuss latest cancer research and guidelines has been postponed out of concern for vulnerable populations.
Read the full notice from the NCCN
POSTPONED: AACR Annual Meeting
April 24-29, 2020
San Diego Convention Center
The American Association for Cancer Research (AACR) Board of Directors has made the difficult decision, after careful consideration and comprehensive evaluation of currently available information related to the novel coronavirus (COVID-19) outbreak, to terminate the AACR Annual Meeting 2020, originally scheduled for April 24-29 in San Diego, California. A rescheduled meeting is being planned for later this year.
Read the full notice from AACR
The Race
May 10, 2020
Legacy Village
The Race is a 5K and one mile walk/run charity event that empowers children and their families to make a difference in the lives of those touched by breast cancer by raising awareness and money for innovative breast cancer research. The Race has been held each Mother's Day for the past sixteen years and to date, The Race, with help from friends, business associates and corporate sponsors, has raised over $1,250,000 for the fight against breast cancer. Proceeds from this year's event will once again benefit the Case Comprehensive Cancer Center.

Participate in the 17th annual event as we work to eradicate breast cancer in our lifetime! Bring your family and make it a Mother's Day to remember. Race participants will receive t-shirts and everyone can enjoy refreshments, clowns, a bounce house, laser tag, face painting and more.
Check out The Race and sign up to participate
Inaugural Tee Off 4 Cancer Golf Classic
June 27, 2020
Mallard Creek Golf Club
The 2020 Tee Off 4 Cancer Golf Classic will take place Saturday, June 27 at Mallard Creek Golf Club in Columbia Station, Ohio. Proceeds benefit the labs of Drs. Vinay Varadan at the Case Comprehensive Cancer Center and Danny Welch at the University of Kansas Cancer Center.

Players may join the classic for $95 which includes golf, range balls, lunch and dinner, plus beer, water, soda and sports drinks throughout play. Sponsorship packages are also available.

Event details and registration
Funding Opportunities
Lung Cancer Research Foundation Funding Opportunities
Deadlines Vary

The Lung Cancer Research Foundation (LCRF) is accepting applications for the following opportunities:

Pilot Grant Program
The LCRF Pilot Grant Program supports high-risk, high-reward research projects investigating a wide variety of topics related to lung cancer.These awards provide a maximum of $150,000 in funding over a period of two years to early- and mid-career investigators.

Research Grant on Disparities in Lung Cancer
To help address inequities and related challenges and with support from the Stavros S. Niarchos Foundation for Charity in memory of Kathryn Louloudis, LCRF is funding several research projects focused on overcoming disparities in lung cancer. These awards provide a maximum of $150,000 over a period of two years to investigators of any career level.
Clinical Cancer Research Career Pathway Grants in Symptom Management
Deadline: April 22, 2020

Conquer Cancer, the ASCO Foundation, and Rising Tide Foundation for Clinical Cancer Research (RTFCCR) have partnered to establish the Conquer Cancer – Rising Tide Foundation for Clinical Cancer Research Career Pathway Grants in Symptom Management to support research in symptom management and build the next generation of clinical researchers in this field.

Each grant pair includes annual funding for the young physician scientist ($100,000/year) and annual funding for a mentor ($15,000/year). Each grant may be awarded for a maximum term of up to four years.

The goal of the Career Pathway Grants in Symptom Management is to recruit and retain individuals committed to conducting symptom management research. This unique grant program will support young physician scientists at a critical time in their academic careers – when they transition from training to principal investigators and begin to set up labs of their own. Through this grant program, these individuals will become leaders in academic research and inspire future generations of physician scientists.
View previously announced funding opportunities
In The News
Facing A Pancreatic Cancer Diagnosis? Get A Virtual Second Opinion
Parma Observer - Mar 1, 2020
 “The data are clear that pancreatic surgery is best performed at high-volume centers to receive the best possible outcome," Jordan Winter, MD says. “However, many patients don't have the resources, connections or geographic proximity to find a specialist. We believe that pancreatic cancer is not only a medical urgency, but a psychologic and emotional emergency. Patients need access to a specialist quickly to get their questions answered and expedite evaluation and treatment."
Artificial intelligence could help tailor game-changing prostate cancer treatment
News 5 Cleveland - Mar 6, 2020
Rates of prostate cancer have long been higher among African American men than white men, and new artificial intelligence research from a biomedical engineering professor at Case Western Reserve University could help tailor treatment to account for cellular differences between black and white prostate cancer patients.
From The NIH
Weekly NIH Funding Opportunities and Notices
Notices
Reminder: FORMS-F Grant Application Forms & Instructions Must be Used for Due Dates On or After May 25, 2020- New Grant Application Instructions Now Available

NIH LATE APPLICATION POLICY Due to Public Health Emergency for United States for 2019 Novel Coronavirus (COVID-19)

General Frequently Asked Questions (FAQs) - Proposal Submission and Award Management Related to COVID-19

Notice of Special Interest (NOSI): Advancing Head and Neck Cancer Early Detection Research (AHEAD)

Funding Opportunities

Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)(PA-20-135)

Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)(PAR-20-131)
Standard Dates Apply

Gastrointestinal (GI) and Microbiome Explorers: Development of Swallowable Smart Pills or Devices for Precision Nutrition, Microbiome and Digestive Disease Applications (R21/R33 Clinical Trial Required)(PAR-20-133)
LOI Deadlines: May 18, 2020; May 8, 2021

Development of Wearable Smart Devices for Continuous Monitoring of Circulating Nutrients, Metabolites and Hormones (R21/R33 Clinical Trial Required)(PAR-20-134)
LOI Deadlines: May 18, 2020; May 8, 2021

Core Infrastructure Support for Cancer Epidemiology Cohorts (U01 Clinical Trial Not Allowed)(PAR-20-136)
Deadlines: April 7, 2020; November 9, 2020; April 9, 2021; November 9, 2021; April 7, 2022; November 9, 2022
View this week's bulletin
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