newsletter masthead
March 22, 2019
AACR Annual Meeting 2019: Highlights from the Case CCC

AACR logo
The 2019 American Association for Cancer Research (AACR) Annual Meeting will take place Friday, March 29 through Wednesday, April 3 in Atlanta, GA. The Case Comprehensive Cancer Center (Case CCC) has compiled a list of posters, mini-symposium sessions and awards featuring Cleveland-based institutions including Cleveland Clinic, University Hospitals Cleveland Medical Center, Cleveland State University and Case Western Reserve University. We are excited to have many members and trainees participating. 

Special congratulations to Yorleny M. Vicioso, a graduate student in Reshmi Parameswaran's lab, who is the recipient of a travel award for her abstract, "A novel combination therapy for treating advanced drug resistant acute lymphoblastic leukemia."

We wish the best of luck to all presenters and attendees!  more>
Huang Receives Gift from the I'm Not Done Yet Foundation for AYA Sarcoma Research
A multi-disciplinary investigator team led by  Alex Huang, MD, PhD  at the Case Comprehensive Cancer Alex Huang Center and the Angie Fowler Adolescent and Young Adult (AYA) Cancer Institute at University Hospitals (UH) Rainbow Babies and Children's Hospital is determined to bring novel immune-based therapeutic options to pediatric and AYA patients suffering from osteosarcoma and other common aggressive sarcomas by providing concept-driving immunotherapeutic approaches.

A gift of $25,000 from the I'm Not Done Yet Foundation will allow investigators to focus on potential applications of existing cancer drugs currently only available to adults affected with multiple myeloma in clinical trials. more>
Defining the Link Between Inflammation and Cancer
A group of scientists led by Xiaoxia Li, PhD at Cleveland Clinic's Lerner Research Institute  defined a new link between inflammation, wound healing and tumor formation. The discovered pathway provides valuable insights into the study of cancers associated with inflammation.

"Our study is the first study to show that a proinflammatory cytokine can recruit a growth factor receptor to activate stem cells in support of tissue repair and tumorigenesis," said Dr. Li, member of the Hematopoietic and Immune Cancer Biology Program of the Case Comprehensive Cancer Center. more>
Cancer Center Seminar Series: "Optimizing Allogeneic Transplant for the Treatment of Acute Leukemia"
Mar 22, 12p | WRB Auditorium

Join us today at noon in the Wolstein Research Building Auditorium to hear John DiPersio, MD, PhD present, "Optimizing Allogeneic Transplant for the Treatment of Acute Leukemia."  Dr. DiPersio is the Virginia E. and Samuel J. Goldman Professor of Medicine,  Chief of the Division of Oncology and Director of the  Siteman Cancer Center at  Washington University School of Medicine. His research focuses on fundamental and translational aspects of leukemia and stem cell biology. These studies include identification of genetic abnormalities in human leukemias, understanding processes involving stem cell and leukemia cell trafficking, and clinical and translational programs in both leukemia/myelodysplastic syndrome and stem cell transplantation.

View a list of upcoming seminars>

The Seminar Series  will  be
available to view via live stream. While we highly encourage you to attend in person to interact with our speakers and receive CME credit, we understand that may not always be possible. Presentations will not be recorded for later viewing, but you may watch the seminar in real time and ask questions via chat.  Watch live at noon>
CDMRP Webinar Series
Next Webinar: March 25, 2019

The Congressionally Directed Medical Research CDMRP logo Programs (CDMRP) presents a webinar series on types of funding opportunities offered and strategies to increase the success of applications submitted to different CDMRP programs.

The next webinar is titled, "Clinical Research and Clinical Trial Funding Opportunities" and will take place Monday, March 25 will highlight the difference between clinical research and clinical trials, key planning considerations for prospective human subject research (e.g. regulatory requirements), and application elements considered in peer and programmatic review of clinical research/trials.

Previous webinars about funding opportunities and strategies for success can be viewed on their website along with a list of upcoming webinars.
Save the Dates! Upcoming VeloSano Fundraising Events for Team Case CCC

Wednesday, April 10
Join us for happy hour at TOLI!
12117 Mayfield Rd
Cleveland, OH 44106

Friday, April 12
Make your own ice cream sundae for $5
WRB Lobby
Join Team Case CCC for "The Race" 2019
May 12, 2019 | Legacy Village
The Race is a 5K and one mile walk/run charity event
that empowers children and their families to make a difference in the lives of those touched by breast cancer by raising awareness and money for innovative breast cancer research. The Race has been held each Mother's Day for the past fifteen years, attracting approximately 1,500 people last year. To date, The Race, with help from friends, business associates and corporate sponsors, has raised over $1,250,000 for the fight against breast cancer. Proceeds from this year's event benefit the Case Comprehensive Cancer Center.

Participate in the 16th annual event as we work to eradicate breast cancer in our lifetime! Bring your family and make it a Mother's Day to remember. Race participants will receive t-shirts and everyone can enjoy refreshments, clowns, bounce house, laser tag, face painting and more. Prizes will be given away throughout the morning.  Join the team>
ASH Award Programs
Deadlines Vary

Multiple awards are available through the American Society of Hematology (ASH). ASH would like  to 
ASH logo
call your attention to a significant change to the Scholar Award Program. Below are brief program descriptions with links to each award. Awards are designed to support those further along in their experience, from fellows to mid-career level hematologists.

The ASH Medical Educators Institute (MEI) is designed to build skills and position junior faculty and senior fellows for successful careers as clinician educators and mentors to future generations of hematologists. The institute consists of three core activities: a  Workshop  at ASH, a  Webinar series  and Mentorship.
Application Deadline: March 31, 2019

Previously, the Scholar Award offered two competitive levels: the Fellow Award and the Junior Faculty Award. Now there are three levels:  the Fellow Award, the Fellow to Faculty Award and the Junior Faculty Award. Previous Junior Faculty applicants may be eligible again. Eligibility has expanded from 10 years of research experience to 13 years of research experience after the terminal degree. 
LOI Deadline: May 1, 2019

ASH Bridge Grant
The ASH Bridge Grant is open to ASH members who have applied for an NIH R01 grant or equivalent and were scored, but not funded. This award is intended to help sustain recipients' research and contribute to their retention in hematology investigation while they reapply.
Deadline: May 1, 2019
Brain Cancer Research Investigator Grant
Deadline: April 1, 2019

Applications are invited for B*CURED's annual Brain Cancer Research Investigator Grant. The one year, $50,000 award is presented to a clinical doctor or research scientist whose primary focus is brain cancer research. Clinical as well as translational projects (in both adult and pediatric brain cancer research) with significant clinical promise will be considered.

Applicant Requirements
Applicants must be faculty at a research institution in North America who are: 
  • Undertaking clinical or translational research, with the intention of applying for R01 NIH funding or the equivalent within 5 years, or
  • Undertaking innovative research to bridge from bench to animal research or to acquire preclinical data from animal models. 
  • Applicants will compose an outstanding research proposal (5 pages maximum) that demonstrates relevance, sound methodological design, and feasibility. 
  • Formal involvement of a biostatistician is required for all clinical trial proposals, but is not required for pre-clinical or translational science proposals. 
ACS Physician Training Awards in Cancer Prevention
Deadline: April 1, 2019

The American Cancer Society's Physician Training Awards in Cancer Prevention are awarded to institutions to support physician 
ACS logo
training  in accredited preventive medicine residency programs that provide cancer prevention and control research and practice opportunities. Awards are made for 4 years in the total amount of $300,000 based on an average of $50,000 per resident training year. 

Cleveland Clinic launches Center for Clinical Artificial Intelligence
Crain's Cleveland Business - Mar 7, 2019
The center will "translate AI-based concepts into clinical tools that will improve patient care and advance medical research," said Cleveland Clinic's Aziz Nazha, MD, director of the new center, associate medical director for AI and member, Case CCC.

Going bald for cancer fundraiser: How St. Baldrick's makes a difference
WKYC - Mar 8, 2019
"We need to find even better treatments and better outcomes for patients," says Alex Huang, MD, PhD in the video highlighting the annual "Shave It Off" event that raises funds for childhood cancer research. Huang is program director of pediatric hematology and oncology at University Hospitals Cleveland Medical Center, professor of pediatrics at CWRU School of Medicine and a member of the Case CCC's Hematopoietic and Immune Cancer Biology Program.

The importance of leaders to invite constructive criticism from others
Oncology Times - Mar 5, 2019
Brian Bolwell, MD, FACP writes about the necessity of growth mindset in his latest contribution to Oncology Times. Dr. Bolwell is Chairman of the Taussig Cancer Institute and Deputy Director for Cleveland Clinic at the Case CCC.
NIH BULLETIN - Notices and Funding Opportunities
Notice of Change to Evaluation of Plans for 'Training in Methods for Enhancing Reproducibility' in NIGMS Training Grant Funding Opportunity Announcements

Notice to Clarify that NIGMS Will Not Accept Applications to Support Scientific Courses through PA-18-648 "Support of Conferences and Scientific Meetings (R13 Clinical Trial Not Allowed)"

Notice of Pre-Application Webinar for PAR-19-219 "Maximizing Access to Research Careers (MARC) (T34)"

Notice of Change in the Number of Trainee Slots on NHGRI T32 Postdoctoral Training Program in Genomic Medicine Research

Notice of Special Interest (NOSI): Computational and Statistical Methods to Enhance Discovery from Health Data

Requests for Applications

Program Announcements

Fri, Mar 22
Hematology and Oncology Grand Rounds
Kirsten Boughan, DO, Assistant Professor, Medicine, CWRU
"Treatment Strategies in PCNSL"
8a Wearn 137

Taussig Cancer Institute Grand Rounds
8a CA5-120

Cancer Center Seminar Series 
John DiPersio, MD, PhD
Virginia E and Samuel J Goldman Professor of Medicine 
Chief, Division of Oncology Deputy Director
Siteman Cancer Center Washington University School of Medicine
" Optimizing Allogeneic Transplant for the Treatment of Acute Leukemia "
12p WRB Auditorium

NCCN Annual Conference
Timothy Gilligan, MD, MS
"Staging of Testicular Cancer: Germ Cell Tumors"
3:25p Orlando, FL
Mon, Mar 25
Genomic Medicine Institute
Masahiro Hitomi, MD, PhD
"PTEN in Cell Fate Decision; Case of Neural Stem Cell"
12p NE1-205

Cancer Center Research Chalk Talk
Youwei Zhang, PhD
1p WRB 3-136
Tues, Mar 26
CWRU SOM Staff Toolkit Session
12p BRB 105

Cancer Imaging Monthly Meeting
1:30p WRB 1-422D
Thurs, Mar 28
Developmental Therapeutics Journal Club
9a N E 6-218

Molecular Biology and Microbiology Seminar
Andrew Mack
1p SOM W203
Fri, Mar 29
Taussig Cancer Institute Grand Rounds
8a CA5-120

AACR Annual Meeting 2019
Mar 29-April 3
Atlanta, GA

Cancer Center Seminar Series
John T. Schiller, PhD
NIH Distinguished Investigator
Center for Cancer Research
National Cancer Institute
"HPV VLPs: Nature Nanoparticles for Cancer Prevention and Treatment"
12p WRB Auditorium
Mon, April 1
Genomic Medicine Institute
Abby Bifano, PhD
Biological Safety Officer
Lerner Research Institute
Cleveland Clinic
Christine McDonald, PhD
IBC Chair
Lerner Research Institute
Cleveland Clinic
"Everything You've Always Wanted to Know About IBC Compliance, but Were Afraid to Ask"
12p NE1-205

Cancer Center Research Chalk Talk
1p WRB 3-136

Tumor Immunology and Immunotherapy Meeting
Suparna Mazumder, PhD
Cleveland Clinic
4p WRB 1-422D
Weds, April 3
Molecular Biology and Microbiology Virology Journal Club
12p WRT 206
Thurs, April 4
Developmental Therapeutics Journal Club
9a NE6-218

Molecular Biology and Microbiology Virology Journal Club
Ivelisse Resto Garay
Popkin Lab
1p SOM W203
Fri, April 5
Taussig Cancer Institute Grand Rounds
8a CA5-120

Cancer Center Seminar Series
William Grady, MD, AGAF
Assistant Professor, Pharmacology
Case Western Reserve University
"Mitochondrial Fission: Structure, Function and Cancer Implications"
12p WRB Auditorium

Deadline: Open

Deadline: Open

Deadline: Open
Case Comprehensive Cancer Center