Gmail users: to ensure you're always viewing the entire newsletter, check at the bottom of the email to see if the newsletter has been "clipped" and click "view entire message" if so.
|
|
Stan Gerson, MD
Director, Case Comprehensive Cancer Center
|
|
Trapl appointed Associate Director for Community Outreach and Engagement
|
I am pleased to announce the appointment of
Erika Trapl, PhD as Associate Director (AD) for Community Outreach and Engagement for the Case Comprehensive Cancer Center (Case CCC). This newly created role will oversee the broad interests and approaches taken by the Case CCC in all aspects of developing community-oriented engagements that have a goal of reducing the burden of cancer throughout our catchment area. Through Dr. Trapl’s leadership, the cancer center will focus on a very ambitious agenda through our members, research programs and community links to establish and coordinate best practices in cancer risk reduction, cancer prevention education and cancer screening, with special attention to vulnerable populations. We will encourage catchment-related research by our investigators for those cancers and risks that are viewed as excessive in our region.
|
|
Erika will chair the
Community Advisory Board and expand that group to include representation from social service entities, health departments and other representatives of our rural communities and regional cities including Lorain, Akron and Canton.
Erika is well suited for this Associate Director role. She has served as Co-Program Leader of the Case CCC’s
Cancer Prevention, Control and Population Research Program since 2019 and has been a cancer center member since 2013. She is an associate professor of population and quantitative health sciences and in February, was
named Director of the
Prevention Research Center for Healthy Neighborhoods (PRCHN) at Case Western Reserve University, having served as Associate Director since its inception in 2009. Erika is trained in epidemiology with a focus on health behavior and statistical methodology. She has successfully facilitated and collaborated with large, multidisciplinary teams, including research teams, that have engaged community partners for most of her career.
|
|
Garcia named Division Chief, Solid Tumor Oncology at University Hospitals Seidman Cancer Center
|
|
|
|
Please join us in congratulating
Jorge A. Garcia, MD, FACP, as he has been named the new Division Chief of Solid Tumor Oncology and the George & Edith Richman Distinguished Scientist Chair at University Hospitals (UH) Seidman Cancer Center, effective April 1.
In this newly created position, Dr. Garcia will develop clinical programs and recruit and develop faculty for GU, GI, breast, lung, head/neck, and melanoma/sarcoma cancer. He will manage clinical trials and mentor junior faculty in developing research proposals and organizing and executing efforts for solid tumor oncology research.
|
|
Dr. Garcia is joining UH after spending more than 15 years at the Cleveland Clinic as a staff physician and member of the Department of Hematology/Oncology and Urology at the Taussig Cancer Institute and Glickman Urological & Kidney Institute. Dr. Garcia also served as The Kerscher Family Chair for Clinical Prostate Cancer Research and director of the advanced prostate cancer research program. Dr. Garcia was an associate professor of medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, concentrating his primary clinical and translational research activities on prostate, kidney and bladder cancers, with a special focus on developmental therapeutics.
He also served as the Chair of the Scientific Protocol Review Committee (PRMC) and, more recently, as the medical director of the clinical research office (CRO) at the
Case Comprehensive Cancer Center.
|
|
From the NIH: Responding to Frequent Questions on Flexibilities Related to NIH Funding and COVID-19
|
|
|
|
Dr. Mike Lauer, National Institutes of Health (NIH) Deputy Director for Extramural Research, provides updates for the research community on flexibilities NIH is providing the community due to the COVID-19 public health emergency.
|
|
COVID-19, your research program at CWRU and upcoming events across the Case Comprehensive Cancer Center
|
|
Case Western Reserve University (CWRU) has
moved to remote course delivery as of last week, in addition to
campus restrictions pertaining to on-campus meetings, gatherings, and conferences. CWRU has also transitioned every possible university function to remote operation to protect the health of the campus community during this rapidly expanding outbreak.
The Case Comprehensive Cancer Center (Case CCC) is continuing to establish virtual meetings where possible and maintain a
current calendar of events as meetings across our partner institutions are postponed, canceled, or made available virtually. At this time,
Case CCC Shared Resources are providing services in a manner that prioritizes safety of facility staff.
The Office of Research and Technology Management has also asked researchers to be prepared for the impact of the Novel Coronavirus might be on their research in various scenarios.
Latest information pertaining to research restrictions is available on the
CWRU Health Updates webpage.
|
|
Recommended Reading: COVID-19 Challenges Basic Researchers
|
|
"As COVID-19 cases have continued to surge, federal agencies such as the Centers for Disease Control and Prevention have called for vigilant social distancing and quarantining to stop the spread. At cancer centers, that has left scientists engaged in basic research facing difficult decisions about which experiments to continue, while securing supplies and creating contingency plans for a complete shutdown," writes the American Association for Cancer Research in a recent article.
The
Case Comprehensive Cancer Center's (Case CCC) Associate Director for Basic Research,
Ruth Keri, PhD shares how researchers at the Case CCC are working in shifts, focused on essential experiements. "We are able to continue to do research, but we don't know how much longer that will happen," says Keri. "We take each day as it comes."
|
|
Join Team Case CCC in VeloSano 2020!
|
The Case Comprehensive Cancer Center (Case CCC) is honored to make its sixth appearance in
VeloSano, a year-round fundraising initiative and "Bike to Cure" weekend to support lifesaving cancer research. Our continuing goal is to bring sustainable funding to cancer research by enlisting the passion and energy of thousands of people who wish to give back... including
YOU! We raised nearly $94,000 in 2019 and every dollar goes directly toward cancer research. In our six years of participation, more than $1,000,000 of VeloSano fundraising totals have come back to the Case CCC to award researchers as pilot funding for cancer research projects.
|
|
The Case CCC will provide complimentary registration fees and jerseys again this year. Contact team captains
Caroline El Sanadi or
Mary Wright for the registration fee waiver code to sign up! While registration is complimentary, all riders are responsible for meeting the minimum fundraising commitment associated with the
distance they ride. Fundraising can begin as soon as you register to ride and continues through October 1, 2020.
Registration is open now and information about volunteering for our cheer station and supporting our team through sponsorship will be available soon!
|
|
Mon, Mar 30
Pathology Defense
Ryan Gimple, Rich Lab
"Analysis of Epigenetic Landscapes Identifies Functional Therapeutic Vulnerabilities in Glioblastoma"
|
|
Weds, April 1
Cancer Microbiome Focus Group
|
|
Fri, April 3
Cancer Center Seminar Series
Angela Ting, PhD
|
|
Mon, April 6
Cancer Center Research Chalk Talk
Pathology Defense
Sahar Mazhar, Narla Lab
"The Role of Germline PP2A Disruption in Cancer Predisposition: Challenges of Using Established Tools to Study PPA2 Inhibition"
|
|
Tues, April 7
Cancer Center Special Seminar
Berkley Gryder, PhD
National Cancer Institute
"Targeting Core Regulatory Transcription Factor Addiction in Cancer"
|
|
Fri, April 10
Cancer Center Special Seminar
Jing Wang, MD, PhD
University of Colorado School of Medicine
"The Interplay between Immunology and Cancer with a Focus on B Cell Lymphoma and Head and Neck Cancer"
|
|
 |
Cancer Center Seminar Series
March 27, 12p
This week's cancer center seminar features
Stanley Huang, PhD presenting, "Stress Sensing and Metabolism of Macrophages in Tumor Immunity" at 12 pm today.
Dr. Huang is assistant professor of pathology at Case Western Reserve University School of Medicine and a member of the Case Comprehensive Cancer Center's Hematopoietic and Immune Cancer Biology Program.
His laboratory focuses on translational immunometabolism deciphering (1) how environmental cytokines, nutrient changes, unusual mediators and cellular signaling control and/or dictate macrophage development and fate in the tumor microenvironment; and (2) systematic interactions between innate immune cells and inflammatory diseases. Ultimately, the goal of his research is to harness and/or exploit the specific metabolic circuits to control immune cell responses and to provide better therapeutic efficacy for controlling cancer and other chronic diseases.
Due to
institutional health restrictions, the seminar will be available virtually via Zoom for the remainder of the series. Attendees will be muted upon entry and are encouraged to submit questions via chat or audio when appropriate.
Note: for best audio quality, we highly advise connecting to audio by phone using the toll number.
|
|
|
|
Cancer Center Seminar Series
April 3, 12p
Dr. Ting is associate staff at Cleveland Clinic Lerner Research Institute and associate professor of molecular medicine and genetics and genome sciences at Case Western Reserve University School of Medicine.
Dr. Ting's research interests focus on epigenetic alterations in human cancers. The Ting laboratory has pioneered next-generation sequencing based DNA methylome assay and analysis and successfully applied these tools for studying genome-wide changes in DNA methylation patterns in prostate, colon and bladder cancers. Her group also leverages other genomic data types, including RNA-seq, polyadenylation site sequencing, and ChIP-seq to help contextualize findings in DNA methylation changes.
A member of the Case Comprehensive Cancer Center's GU Malignancies program, Dr. Ting will present, "DNA Methylation at the Intersect of Chromatin Structure and Transcriptome Diversity."
|
|
|
|
|
Core Facilities and Shared Resources Symposium
April 28, 2020
Opening remarks from Provost Ben Vinson III will begin at 8:30 am. This opportunity for networking and discovery will feature:
- plenary talks from CWRU faculty from various schools/colleges
- breakout sessions celebrating how our cores create a continuum of discovery across multiple disciplines and providing administrative technical assistance about running a Core
- poster sessions showing the work our facilities make possible
Please note: at this time, the event is still welcoming registration as organizers explore options for potentially hosting the program remotely.
|
|
|
|
Call for Abstracts and Registration: Cancer Stem Cell Conference 2020
August 4-6, 2020
Tinkham Veale University Center
The Case Comprehensive Cancer Center and the National Center for Regenerative Medicine invite you to submit an abstract and register for CSC 2020!
Now in its fourth year, CSC 2020 will feature renowned thought leaders in the field of cancer stem cell research. This conference is guaranteed to offer cutting-edge keynote presentations from a variety of niches within the field. Join world-class investigators for this three-day summit and network with scientists and clinicians advancing cancer stem cell research and therapeutic applications.
The
Cancer Stem Cells Conference call for abstracts affords an exciting opportunity to highlight cancer stem cell focused research, providing a forum to showcase basic research, as well as novel technologies and translational therapeutic strategies. Basic science, clinical and translational researchers, as well as trainees, are invited to
submit abstracts by 5 pm EST, Friday, May 29, 2020.
Symposia topics include, but are not limited to: developmental biology, immune interaction, microenvironment, cellular metabolism, epigenetic regulation, druggable targets and emerging technologies.
|
|
|
|
|
Save The Date: Great Lakes Breast Cancer Symposium 2020
October 4-6, 2020
Tinkham Veale University Center, CWRU
As host site for the 2020 Great Lakes Breast Cancer Symposium, the Case Comprehensive Cancer Center encourages you to mark your calendar for the symposium taking place October 4-6, 2020.
The symposium highlights ongoing basic, translational, clinical and population studies addressing the biological mechanisms, management and prevention of breast cancer. Researchers from participating institutions will share their exciting work with a goal to develop cross-institutional collaborations.
This year's event features two keynote speakers:
- Carlos Arteaga, MD, Director of the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center
- Helen Piwnica-Worms, PhD, Professor of Experimental Radiation Oncology at the University of Texas MD Anderson Cancer Center
|
|
|
|
Additional Upcoming Events
|
|
|
POSTPONED:
AACR Annual Meeting
April 24-29, 2020
San Diego Convention Center
|
The American Association for Cancer Research (AACR) Board of Directors has made the difficult decision, after careful consideration and comprehensive evaluation of currently available information related to the novel coronavirus (COVID-19) outbreak, to terminate the AACR Annual Meeting 2020, originally scheduled for April 24-29 in San Diego, California. A rescheduled meeting is being planned for later this year.
|
|
|
|
Inaugural Tee Off 4 Cancer Golf Classic
June 27, 2020
Mallard Creek Golf Club
|
The 2020 Tee Off 4 Cancer Golf Classic will take place Saturday, June 27 at Mallard Creek Golf Club in Columbia Station, Ohio. Proceeds benefit the labs of Drs.
Vinay Varadan at the Case Comprehensive Cancer Center and
Danny Welch at the University of Kansas Cancer Center.
Players may join the classic for $95 which includes golf, range balls, lunch and dinner, plus beer, water, soda and sports drinks throughout play. Sponsorship packages are also available.
|
|
|
|
New Funding Opportunities at the Case CCC
In addition to extending deadlines for many open funding opportunities, the Case Comprehensive Cancer Center recently released the following awards:
Available award: $50,000
Deadline: April 17, 2020
Available award: $50,000
Deadline: May 8, 2020
Available award: $50,000
Deadline: May 8, 2020
|
|
Deadline: May 26, 2020
The AACR-Bayer Stimulating Therapeutic Advances through Research Training (START) Grants will provide support to postdoctoral or clinical research fellows, combines research experiences in both an academic and industry setting, following a research timeline that will be of greatest benefit to the proposed work.
The training provided through this grants program will be invaluable to young investigators, by allowing fellows to attain a comprehensive research experience that will make them highly desirable to potential employers in either academic research or the pharmaceutical industry. Likewise, academic research centers and industry will benefit from the introduction of such dual-trained individuals into the field.
Each fellowship provides a
three-year grant of $225,000 to support the salary and benefits of the fellow while working on a mentored cancer research project. Research projects may be clinical or translational in nature and must have direct applicability and relevance to clinical translation and development in solid tumors and hematologic malignancies. Proposals focused on clinical research are highly encouraged. Applicants must plan to spend one year on site at a Bayer facility.
|
|
The Department of Defense and its Congressionally Directed Medical Research Programs (CDMRP) have announced program details and application instructions for the following fiscal year 2020 programs. Deadlines and eligibility vary.
|
|
- Virtual Cancer Center Director Award
- Career Development Award
- Idea Award
- Impact Award
- Behavioral Health Science Award
- Translational Team Science Award
- Career Development Award
- Clinical Translational Research Partnership Award
- Concept Award
- Idea Development Award
- Investigator-Initiated Translational Research Award
- Early Investigator Research Award
- Physician Research Award
|
|
Today - Mar 13, 2020
Cleveland Clinic medical oncologist
Halle Moore, MD explains how individuals currently receiving immune-suppressive treatment and those with active cancer are at higher risk for infection. Dr. Moore is a member of the
Case CCC's Cancer Prevention, Control & Population Research Program.
|
|
The Daily - Mar 23, 2020
Students from the
Case Western Reserve University School of Medicine are stepping up as volunteers to answer calls from the public related to the coronavirus pandemic.
Case CCC member
Heidi Gullett, MD, MPH is one of several faculty organizing the impressive effort at local community health centers.
|
|
Weekly NIH Funding Opportunities and Notices
|
Notices
Funding Opportunities
Deadline: June 16, 2020
Deadline: June 23, 2020
Deadline: June 23, 2020
|
|
Use the button below to submit all your news, events, announcements and communications requests to the Case CCC Marketing and Communications team!
|
|
|
|
|
|
|
